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Credence

Genomics
decode your future

Credence Genomics
A pioneer in Genomic research and
diagnostics in Sri Lanka.
The first and the only Next Generation
Sequencing service provider in Sri Lanka.
Aims to deliver novel, rapid approaches to
DNA sequencing for Genomic research and
diagnostics using Next Generation
Sequencing.

Credence Technology Platform

Ion Torrent PGM From Life Technologies, USA

DNA Sequencing
DNA Sequencing is the process of determining
the precise order of nucleotides within a DNA
molecule.

Conventional Sequencing

Manual Sequencing & Sanger Sequencing


a DNA molecule is sequenced only once
Slow, Expensive and Less Reliable

Next Generation Sequencing (NGS)


Parallelize the sequencing process, producing
thousands or millions of sequences simultaneously
from one or many genes.
NGS

DNA Sequence
read
simultaneously
many times
during a test

Sanger
Sequencing

DNA Sequence
read only once
during a test

Faster, Cheaper and More Reliable Results

Next Generation Sequencing (NGS)


Parallelize the sequencing process, producing
thousands or millions of sequences simultaneously
from one or many genes.

Gene Panel Tests

Next Generation Sequencing (NGS)


It also enables detection of one or more bacteria or
fungi present in blood or body fluids in one go.

Metagenomic Tests

Credence Products

BactFast
FungiFast
CredenceCarrier
CredenceNBS
CredenceTumour
CredenceBreast
CredenceColoRectal

BactFast

FungiFast

BactFast
A culture independent test for ALL known BACTERIA in
any biological sample.
Tests for >1500 bacteria
Detects the presence of multiple different types of
bacteria and their relative abundance
Results available in two levels (genus level or species
level) within in 24 hours
No more Long waits or Culture failures
Test Sample: Blood or Any Body Fluids

FungiFast
A culture independent test for ALL known FUNGI in any
biological sample.
Tests for >500 Fungi
Detects the presence of multiple different types of fungi
and their relative abundance
Results available within in 24 hours
No more Long waits or Culture failures
Test Sample: Blood or Any Body Fluids

CredenceCarrier
A gene panel test that tests 325 genes
responsible for 853 inherited disorders
simultaneously.
can be used for
Carrier screening at any time: eg Before Marriage
Diagnostic testing when a child is affected with a
condition that can not be diagnosed with conventional
tests.
Test Sample: Blood

CredenceNBS
A gene panel test that tests 28 genes
responsible for 46 metabolic disorders
simultaneously.
can be used for
Newborn Screening
Diagnostic testing when a child is affected with a
suspected metabolic disorder.
Test Sample: Blood

CredenceTumour
A gene panel test that tests 50 genes that drive
cancer and are pharmacogenomic targets for
tailoring cancer therapy.
ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR,
ERBB2, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAS, GNAQ,
HNG1a, HRASM, IDH1, JAK3, IDH2, KDR, KIT,KRAS,MET,MLH1, NOTCH1,
NPM1, NRAS, PDFGRA, PTEN, TEPN11, RB1,RET,SMAD4,SMARCB1,SMO, SRC,
STK11,TP53, VHL

can be used to personalize cancer therapy


Test Sample: Tumour Tissue (Fresh or FFPE)

CredenceBreast
A gene panel test that tests 18 genes that are
responsible for inherited predisposition to
breast cancer.
ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, MRE11A, MUTYH, NBN,
NF1, PALB2, PTEN, RAD50, RAD51C, RAD51D, STK11 and TP53

can be used to personalize prevention

Test Sample: Blood

CredenceColoRectal
A gene panel test that tests 13 genes that are
responsible for inherited predisposition to
colorecal cancer.
APC,BMPR1A, CDH1, CHEK2, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN,
SMAD4, STK11, TP53

can be used to personalize prevention

Test Sample: Blood

Credence Products

BactFast
FungiFast
CredenceCarrier
CredneceNBS
CredenceTumour
CredenceBrest
CredenceColoRectal

BactFast

FungiFast

credencegenomics.com

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