Pharmacological

CLASSIFICATION
OF
DRUGS
with
Doses and
Preparations
 Pharmacological
CLASSIFICATION
OF DRUGS
with
Doses and
Preparations
THIRD EDITION

KD Tripathi
MD
Ex-Director-Professor and Head of Pharmacology
Maulana Azad Medical College and associated
LN and GB Pant Hospitals
New Delhi

JAYPEE BROTHERS
MEDICAL PUBLISHERS (P) LTD
New Delhi
Published by
Jitendar P Vij
Jaypee Brothers Medical Publishers (P) Ltd
EMCA House, 23/23B Ansari Road, Daryaganj
New Delhi 110 002, India
Phones: +91-11-23272143, +91-11-23272703, +91-11-23282021, +91-11-23245672
Fax: +91-11-23276490, +91-11-23245683 e-mail: jaypee@jaypeebrothers.com
Visit our website: www.jaypeebrothers.com

Branches
2/B Akruti Society, Jodhpur Gam Road, Satellite, Ahmedabad 380 015
Phones: +91-079-30988717, +91-079-26926233 e-mail: jpamdvd@rediffmail.com
202 Batavia Chambers, 8 Kumara Krupa Road, Kumara Park East
Bangalore 560 001, Phones: +91-80-22285971, +91-80-22382956, +91-80-30614073
Tele Fax: +91-80-22281761 e-mail: jaypeemedpubbgl@eth.net
282 IIIrd Floor, Khaleel Shirazi Estate, Fountain Plaza
Pantheon Road, Chennai 600 008, Phones: +91-44-28262665, +91-44-28269897
Fax: +91-44-28262331 e-mail: jpchen@eth.net
4-2-1067/1-3, Ist Floor, Balaji Building, Ramkote
Cross Road, Hyderabad 500 095, Phones: +91-40-55610020, +91-40-24758498
Fax: +91-40-24758499 e-mail: jpmedpub@rediffmail.com
1A Indian Mirror Street, Wellington Square, Kolkata 700 013,
Phones: +91-33-22456075, +91-33-22451926 Fax: +91-33-22456075
e-mail: jpbcal@cal.vsnl.net.in
106 Amit Industrial Estate, 61 Dr SS Rao Road, Near MGM Hospital
Parel, Mumbai 400 012, Phones: +91-22-24124863, +91-22-24104532, +91-22-30926896
Fax: +91-22-24160828 e-mail: jpmedpub@bom7.vsnl.net.in
e-mail: jpmedpub@bom7.vsnl.net.in
KAMALPUSHPA, 38 Reshimbag, Opp. Mohota Science College
Umred Road, Nagpur 440 009, Phones: +91-712-3945220, +91-712-2704275
Fax: +91-712-2704275 e-mail: jpmednagpur@rediffmail.com

Pharmacological Classification of Drugs with Doses and Preparations

2006, KD Tripathi

All rights reserved. No part of this publication should be reproduced, stored in a retrieval system,
or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise,
without the prior written permission of the author and the publisher.
This book has been published in good faith that the material provided by author is original. Every
effort is made to ensure accuracy of material, but the publisher, printer and author will not be held
responsible for any inadvertent error(s). In case of any dispute, all legal matters to be settled under
Delhi jurisdiction only.

First Edition : 1986

Second Edition : 1990
Third Edition : 2006

ISBN 81-8061-790-4

Typeset at JPBMP typesetting unit

Printed at Gopsons Papers Ltd., A-14, Sector 60,Noida
 Preface

A systematized listing of drugs according to their primary

actions, characteristics and/or clinical uses is the first step
to learn about them. The mental exercise to prescribe a drug
for a patient starts with identifying the class of drugs to
be prescribed and then selecting the specific member most
appropriate for that patient according to its subclass/
group/individual characteristic. For example, the first
thing one decides is whether an analgesic or an
antihypertensive or an antibiotic is to be prescribed; then
proceeds to consider which type of analgesic (opioid/
nonopioid), or antihypertensive ( blocker/ACE inhibitor,
etc.), or antibiotic (-lactam/fluoroquinolone, etc.), and
which specific member is most suitable. On the other hand,
every drug is known by its class/subclass, e.g. furosemide
is a high-ceiling diuretic, glibenclamide is a sulfonylurea
antidiabetic. Thus, the importance of grouping and
compartmentalizing drugs cannot be over-emphasized. The
phenomenal increase in the number of drugs in recent
years has further underscored the need for drug
classifications.
However, drug classifications have been criticised for
being arbitrary and imperfect because of nonuniform
criteria often adopted and frequent lack of watertight
distinctions among drugs of different subgroups. Neverthe-
less, basing on pharmacological differences and applying
a practical approach, meaningful drug classifications can
be devised, as has been done in this booklet. The
continuing demand of previous editions of this booklet for
vi Preface
the past 20 years is a testimony to the utility of this
approach. The present edition has been thoroghly revised
and updated to include drugs marketed till Dec. 2005.
To be useful to medical/pharmacy students as well as
to practitioners, the doses (including pediatric doses
wherever relevant), frequency and route(s) of administra-
tion along with leading brand names of drugs and different
types of dosage forms (oral, parenteral, topical, etc.) are
listed distinctively after each class of drugs. Thus, essential
prescribing information has also been incorporated. Single
drug formulations are mainly mentioned. Combined drug
formulations find a place wherever important or relevant.
The listing of brand names is restricted to only 14 per
drug, and is not exhaustive. Synonyms and alternative
names of drugs and classes of drugs are also mentioned.
Two separate indices, one of nonproprietary (generic)
names and the other of proprietary (brand) names of drugs
have been provided for ready reference.
It is hoped that the booklet will coutinue to serve as
an aid to remembering drug names, knowing about them,
and prescribing them rationally. The cooperation and
encouragement of M/s Jaypee Brothers is thankfully
acknowledged.

New Delhi K.D. Tripathi

6th April 2006
 Explanatory Notes

1. The proprietary (brand) names appear in capital

letters. The information on dosage form(s) is printed in
maroon colour.
2. The doses and regimens are given in smaller type,
while nonproprietary (generic) names appear in bigger
type.
3. If no brand name of a drug is listed, it is not currently
marketed in India, or is marketed only in combinations.
This can be found out from the composition of the
combined formulation given.
4. If the route of administration is not specified, the drug
is administered only orally, and the dose mentioned is
the oral dose.
5. Drug doses mentioned without specifying frequency of
administration indicate the quantity for a single dose.
 Abbreviations

amp Ampoule
AP Action potential
BD Twice daily
BSA Body surface area
cap Capsule
Ch Child dose
cm Centimeter
CR Continuous release
Distab Dispersible tablet
DS Double strength
DTPA Diethylene triamine pentaacetic acid
e.c. Enteric coated
ER Extended release
ERP Effective refractory period
ext Extract
g Gram
GITS Gastrointestinal therapeutic system
hr hour
i.m. Intramuscular
inj Injection
IU International unit
i.v. intravenous
kg Kilogram
L Litre
LES Lower esophageal sphincter
liq Liquid
m Meter
max Maximum
x Abbreviations

mEq Milliequivalent
mg Milligram
min Minute
ml Millilitre
MR Modified release
MU Mega (million) unit
MW Molecular weight
g Microgram
OD Once daily
oint Ointment
Pot. Potassium
QID Four times a day
rDNA Recombinant deoxyribonucleic acid
s.c. Subcutaneous
s.l. Sublingual
Sod Sodium
SR Sustained release
susp Suspension
syr Syrup
tab Tablet
TCID50 Tissue culture infective dose 50%
TDS Three times a day
THFA Tetrahydrofolic acid
TTS Transdermal therapeutic system
U Unit
UV Ultra violet
yr Year (age)
ZE Zollinger-Ellison
 Contents

1. Drugs Acting on Autonomic Nervous System ....... 1

Cholinergic Drugs, Anticholinergic Drugs, Drugs Acting on
Autonomic Ganglia, Adrenergic Drugs, -Adrenergic Blocking
Agents, -Adrenergic Blocking Agents, Drugs used for
Glaucoma

2. Autacoids and Related Drugs .................................. 13

Histaminergic Agonists, H1-Antagonists, 5-Hydroxytry-
ptamine (5-HT) Antagonists, Drugs for Migraine,
Prostaglandins (PGs) and their Analogues, Antipyretic-
Analgesics and Nonsteroidal Antiinflammatory Drugs
(NSAIDs), Antirheumatoid Arthritis Drugs, Antigout Drugs

3. Drugs for Respiratory Disorders ............................. 23

Drugs for Cough, Drugs for Bronchial Asthma

4. Hormones and Related Drugs ................................. 30

Anterior Pituitary Hormones and Related Drugs, Thyroid
Hormone, Thyroid Inhibitors, Antidiabetic Drugs,
Corticosteroids, Androgens and Related Drugs, Estrogens and
Related Drugs, Progestins, Oral Contraceptives, Uterine
Stimulants, Uterine Relaxants

5. Drugs Acting on Peripheral (somatic)

Nervous System .......................................................... 47
Skeletal Muscle Relaxants, Local Anaesthetics

6. Drugs Acting on Central Nervous System ........... 51

General Anaesthetics, Preanaesthetic Medication, Sedative-
Hypnotics, Antiepileptic Drugs, Antiparkinsonian Drugs,
Antipsychotic Drugs, Antianxiety Drugs, Antidepressants,
Drugs for Mania and Manic-Depressive (Bipolar) Disorder,
Opioid Analgesics, Complex Action Opioids and Opioid
Antagonists, Central Nervous System Stimulants, Cognition
Enhancers
xii Contents
7. Cardiovascular Drugs ................................................ 66
Antihypertensive Drugs, Antianginal Drugs, Drugs for
Peripheral Vascular Diseases, Drugs for Congestive Heart
Failure, Antiarrhythmic Drugs

8. Drugs Acting on Kidney ........................................... 75

Diuretics, Antidiuretics

9. Drugs Affecting Blood .............................................. 78

Haematinics, Coagulants, Anticoagulants, Fibrinolytics,
Antifibrinolytics, Antiplatelet Drugs, Hypolipidaemic Drugs,
Plasma Expanders

10. Gastrointestinal Drugs .............................................. 88

Drugs for Peptic Ulcer, Antiemetics, Drugs for
Gastroesophageal Reflux Disease, Laxatives, Nonspecific
Antidiarrhoeal Drugs

11. Antibacterial Drugs .................................................... 97

Sulfonamides, Cotrimoxazole, Quinolones, Beta-Lactam
Antibiotics (Penicillins, Cephalosporins, Monobactams,
Carbapenems), Aminoglycoside Antibiotics, Tetracyclines,
Chloramphenicol, Macrolide Antibiotics, Lincosamide
Antibiotics, Glycopeptide Antibiotics, Oxazolidinone,
Polypeptide Antibiotics, Urinary Antiseptics, Antitubercular
Drugs, Antileprotic Drugs

12. Antifungal, Antiviral, Antiprotozoal and

Anthelmintic Drugs .................................................. 114
Antifungal Drugs, Antiviral Drugs, Antimalarial Drugs,
Antiamoebic Drugs, Drugs for Giardiasis, Drugs for
Trichomoniasis, Drugs for Leishmaniasis, Anthelmintics

13. Anticancer Drugs ...................................................... 126

Antineoplastic Drugs

14. Miscellaneous Drugs ...............................................130

Immunosuppressants, Chelating Agents, Locally Acting Drugs
on Skin and Mucous Membranes, Antiseptics and Disinfectants,
Ectoparasiticides, Vaccines, Antisera and Immuneglobulins

Index of Nonproprietary Names of Drugs ................. 145

Index of Proprietary (Brand) Names of Drugs .......... 162
Backcover
Pharmacological Classification of Drugs, with doses and
preparations, 3rd edition is a systematic and updated listing
of drug classifications to serve as an aid to remembering
drug names and quickly placing them in their appropriate
pharmacological/therapeutic category. Such a
systematized listing has become particularly relevant in
view of the introduction of a large number of new drugs.
Essential prescribing information, Viz. doses, routes and
frequency of administration and a limited number of
leading proprietary (brand) names along with dosage forms
of drugs has been provided to make it useful to both
medical/pharmacy students as well as professionals.