Alabang-Zapote Road, Pamplona 3, Las Pias City, Metro Manila 1740,

PHILIPPINESwww.perpetualdalta.edu.ph +63(02) 871-06-39

MECHANISM OF INDICATION AND NURSING

DRUG SIDE EFFECTS
ACTION CONTRAINDICATION RESPONSIBILITY
Generic Name: Produces analgesia by Temporary relief of BODY AS A WHILE: 1. Monitor S&S of:
Acetaminophen, unknown mechanism, mild to moderate pain. Negligible with hepatotoxicity, even
Paracetamol perhaps by action on recommended dosage; with moderate
peripheral nervous Hypersensitivity to rash acetaminophen doses,
Brand Name: system. acetaminophen or ACUTE POISONING: especially in
Panadol, Tylenol Reduces fever by direct phenacetin; use with Anorexia, nausea, individiuals with poor
action on alcohol. vomiting, dizziness, nutrition or who have
hypothalamus heat- lethargy, diaphoresis, ingested alcohol over
Classification: regulating center with chills, epigastric or prolonged periods;
CNS Agent; consequent peripheral abdominal pain, poisoning, usually
Nonnarcotic Analgesic; vasodilation, diarrhea; onset of from accidental
Antipyretic sweating, and hepatotoxicity ingestion or suicide
dissipation of heat. elevation of serum attempts, potential
Unlike aspirin, transaminase (ALT, abuse from
Dosage/Frequency: acetaminophen has AST) and psychological
500 mg little effect on platelet thrombocytopenic dependence
PO Q6 for pain aggregation, does not purpura, hepatotoxicity (withdrawal has been
affect bleeding time, in alcoholics, renal associated with
and generally damage restless and excited
produces no gastric responses).
bleeding.

41
 Alabang-Zapote Road, Pamplona 3, Las Pias City, Metro Manila 1740,
PHILIPPINESwww.perpetualdalta.edu.ph +63(02) 871-06-39

MECHANISM OF INDICATION AND NURSING

DRUG SIDE EFFECTS
ACTION CONTRAINDICATION RESPONSIBILITY
Generic Name: Produces analgesia by Temporary relief of BODY AS A WHILE: 1. Monitor S&S of:
Acetaminophen, unknown mechanism, mild to moderate pain. Negligible with hepatotoxicity, even
Paracetamol perhaps by action on recommended dosage; with moderate
peripheral nervous Hypersensitivity to rash acetaminophen doses,
Brand Name: system. acetaminophen or ACUTE POISONING: especially in
Panadol, Tylenol Reduces fever by direct phenacetin; use with Anorexia, nausea, individiuals with poor
action on alcohol. vomiting, dizziness, nutrition or who have
hypothalamus heat- lethargy, diaphoresis, ingested alcohol over
Classification: regulating center with chills, epigastric or prolonged periods;
CNS Agent; consequent peripheral abdominal pain, poisoning, usually
Nonnarcotic Analgesic; vasodilation, diarrhea; onset of from accidental
Antipyretic sweating, and hepatotoxicity ingestion or suicide
dissipation of heat. elevation of serum attempts, potential
Unlike aspirin, transaminase (ALT, abuse from
Dosage/Frequency: acetaminophen has AST) and psychological
500mg little effect on platelet thrombocytopenic dependence
PO Q4 for fever aggregation, does not purpura, hepatotoxicity (withdrawal has been
affect bleeding time, in alcoholics, renal associated with

42
 Alabang-Zapote Road, Pamplona 3, Las Pias City, Metro Manila 1740,
PHILIPPINESwww.perpetualdalta.edu.ph +63(02) 871-06-39

and generally damage restless and excited

produces no gastric responses).
bleeding.

MECHANISM OF INDICATION AND NURSING

DRUG SIDE EFFECTS
ACTION CONTRAINDICATION RESPONSIBILITY
Generic Name: An antibiotic that Infections caused by GI: diarrhea, nausea, 1. Assess bowel pattern
Amoxicillin and combines amoxicillin susceptible beta- vomiting before and during
Clavulanate Potassium and clavulanic acid. It lactamase-producing SKIN: Rash, urticarial treatment as
(Co-amoxiclav) destroys bacteria by organisms: lower OTHER:Candidal pseudomembranous
disrupting their ability respiratory tract vaginitis; moderate colitis may occur.
Brand Name: to form cell walls. infections, acute increases in serum ALT, 2. Report hematuria or
Augmentin, Clavulin Clavulanic acid blocks bacterial sinusitis, AST; oliguria as high doses
the chemical defense, community acquired glomerulonephritis; can be nephrotoxic.
known as beta- pneumonia, otitis agaranulocystosis (rare) 3. Assess respiratory
Classification: lactamase that some media, sinusitis, skin status.
Antiinfective; bacteria have against and skin structure 4. Observe for
Beta-lactam antibiotic; penicillin. infections and UTI. anaphylaxis.
Aminopenicillin 5. Ensure that the
Co-amoxiclav is active
Combination shares patient has adequate
against bacterial
toxic potential of fluid intake during
infections that have
any diarrhea attack.

43
 Alabang-Zapote Road, Pamplona 3, Las Pias City, Metro Manila 1740,
PHILIPPINESwww.perpetualdalta.edu.ph +63(02) 871-06-39

Dosage/Frequency: become resistant to ampicillin. 6. Note: Generalized,

625 mg 1 tab amoxicillin. Hypersensitivity to erythematous,
BID x 7 days penicillin; infectious maculopapular rash is
mononucleosis. not due to
hypersensitivity. It is
usually mild, but can
be severe. Report
onset of rash to
physician, since
hypersensitivity
should be ruled out.

MECHANISM OF INDICATION AND NURSING

DRUG SIDE EFFECTS
ACTION CONTRAINDICATION RESPONSIBILITY
Generic Name: Induces peristaltic To relieve constipation Systemic effects not 1. Evaluate periodically
Bisacodyl contractions by direct in patients with spinal reported. patients need for
stimulation of sensory cord damage. Mild cramping, nausea, continued use of
Brand Name: nerve endings in the diarrhea, fluid and drug; bisacodyl
Bisacolax, Deficol, colonic wall. Acute surgical electrolyte disturbances usually produces 1 or
Dulcolax abdomen, nausea, (especially potassium 2 soft formed stools
vomiting, abdominal and calcium) daily.
cramps, intestinal 2. Monitor patients
Classification: receiving concomitant

44
 Alabang-Zapote Road, Pamplona 3, Las Pias City, Metro Manila 1740,
PHILIPPINESwww.perpetualdalta.edu.ph +63(02) 871-06-39

Gastrointestinal agent; obstruction, fecal anticoagulants.

Stimulant Laxative impaction; use of Indiscriminate use of
rectal suppository in laxative results in
presence of anal or decreased absorption
Dosage/Frequency: rectal fissures, of vitamin K.
2 suppository STAT ulcerated hemorrhoids,
proctitis

45