Animal Physiology 341 Name(s) ________________________

Laboratory: Endocrine Physiology

Case Study

A 36-year-old man presented to the emergency room complaining of heart palpations and
extreme anxiety, which he stated began approximately 18 months ago. He also stated that he
has lost a significant amount of weight, despite an extreme increase in his appetite. In
addition, he complained of heat intolerance. The physical exam revealed an enlarged thyroid
gland. Laboratory results are as follows:

Basal metabolic rate: +30 % above normal

Plasma glucose: normal
Iodine uptake: above normal

1. What is the pathology or hormone imbalance?

2. Which of the following should be administered in order to treat the patients disorder?
Briefly explain your choice.

a) propylthiouracil (PTU)
b) thyroxine
c) thyroid-stimulating hormone (TSH)
d) thyrotropin-releasing hormone (TRH)

3. What should the physician be concerned about when prescribing the chosen treatment?