Mechanism of Nursing

Name of Drug Indication Contraindication Side Effect

Actions responsibilities
Generic Name:
Isosorbide dinitrate It relaxes vascular Dinitrate: Treatment Contraindicated with Frequent: Assessment:
smooth muscle with and prevention of allergy to nitrates, Headache, >History: Allergy to
Brand Name: a resultant decrease angina pectoris severe anemia, head Dizziness, Weakness, nitrates, severe
Isoket in venous return and trauma, cerebral Nausea, Flushing, a anemia, GI
decrease in arterial hemorrhage, drop in blood hypermobility, head
Classification: BP, which reduces hypertrophic pressure that occurs trauma, cerebral
Antianginal left ventricular cardiomyopathy, when moving from a hemorrhage,
workload and narrow-angle lying down or sitting hypertrophic
Dosage: decreases myocardial glaucoma, postdural position to sitting or cardiomyopathy,
Injection: 0.5 mg/ml oxygen hypotension standing, which pregnancy, lactation
consumption. results in dizziness Physical: Skin color,
Route: Use cautiously with and lightheadedness T, lesions;
I.V pregnancy, lactation, (postural orientation, reflexes,
acute MI, CHF. hypotension), affect; P, BP,
Increased heart rate orthostatic BP,
(tachycardia), baseline ECG,
Decreased heart rate peripheral perfusion;
(bradycardia), R, adventitious
Allergic skin sounds; liver
reactions, Fainting. evaluation, normal
output; CBC, Hgb

> Give sublingual

preparations under
the tongue or in the
buccal pouch;
discourage the
patient from
swallowing.
>Create a nitrate-free
period to minimize
tolerance.
> Keep life support
equipment readily
available if overdose
occurs or cardiac
condition worsens.
> Gradually reduce
dose if anginal
treatment is being
terminated; rapid
discontinuation can
lead to problems of
withdrawal.