Figre 1: Phtmicrgraphs f sse taken frm prtal plaqe.

(a) Lw
pwer view shwing dct >150 , (b) High pwer view f the abve
shwing desqaman f epithelim and inamman (H and Estain),
and (c and d) Prtal plaqe, slid type lacking in biliary channels, high
and lw pwer view

Table 1: Age at peran, large bile dcts and DPM in srvivrs and pr
tcme grp
Factors Poor outcome (%) Survivors (%) Figre 2: Phtmicrgraphs shwing di erent degrees f brsis:
(a) Mild, (b) Mderate, (c and d) Severe (H and E stain)
Age at operaon (P=0.541) 89.6 days 66.8 days
Large bile ducts (>150 ) (P=0.021) 17 (26) 32 (70)
DPM (P=0.055) 13 (24) Nil
Fishers exact test with FreemanHalton extension two-tailed P = 0.055; DPM: Ductal plate
malformaon

Table 2: Degree f brsis amng the srvivrs and pr tcme grp

Outcome Fibrosis Fibrosis Fibrosis Total
score 1+ (%) score 2+ (%) score 3+ (%)
Survivors 8 (57) 5 (36) 1 (7) 14
Poor outcome 5 (9) 23 (43) 26 (48) 54
Total 13 28 27 68
Fishers exact test with FreemanHalton extension two-tailed P = 0.001

Table 3: Grade f BDP amng the srvivrs and pr tcme grp

Outcome BDP 1+ BDP 2+ BDP 3+ Total
mild (%) moderate (%) severe (%)
Survivors 4 (29) 7 (50) 3 (21) 14
Poor outcome 3 (5) 28 (52) 23 (43) 54 Figre 3: Phtmicrgraphs shwing varying grades f bile dctlar
Total 7 35 26 68 prliferan: (a) Mild, (b) Mderate, (c and d) Severe in lw and high
Fishers exact test with FreemanHalton extension two-tailed P = 0.035; BDP: Bile duct proliferaon pwer respecvely (H and E stain)
 Figre 5: Phtmicrgraphs f secns f liver taken frm cases f
Figre 4: Immnstaining fr cytkerat in ant ibdy fr shwing
dctal plate malfrman. (a) Irreglar clsters f misshapen and
t he degree f bile dct prliferat in. (a) Lw pwer view and
crvilinear bile dct s arranged arnd small arteriles. (b) High
(b) High pwer view f severe degree f dctlar prliferatin with
pwer view shwing misshapen dcts with vergrwth f nderlying
prminent fibrsis
cnnecve sse (H and E stains)
et al.

et al.

et al.

et al.
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