Patho 108 Chapter 2 Critical Thinking Questions Fluid, Electrolyte, and Acid-Base Imbalances 1.) Very high hydrostatic pressure in the venule end of a capillary affects fluid by preventing the return of fluid from the interstitial compartment to the venous end. This increases blood pressure and can cause pulmonary edema, hypervolemia, CHF. 2.) A loss of plasma proteins affects the fluid shift in the capillaries because plasma proteins usually remain inside the capillary and rarely move through the semipermeable capillary membrane. Fewer plasma proteins in the capillary allows more fluid to leave and less to return to the venous end. 3.) When there is a high concentration of sodium ion levels, they promote accumulation of fluid in the interstitial compartment by increasing the ISF osmotic pressure and decreasing the return of fluid to the blood. This causes an increase in blood pressure and blood volume. 4.) The lymph nodes filter and if there is damage or inflammation in the area where a blood draw, injection or IV has occurred the fluid will build up and have no place to be filtered and go. This will create painful and life threatening edema in the arm. 5.) If there is poor circulation as well the gravity does not allow the excess fluid to circulate throughout the body. When lying down there is less gravitational pull of the fluid to the feet and legs and it allows for systemic circulation to occur. 6.) Excessive perspiration and fever creates a loss of sodium chloride which results in hyponatremia and hypochloremia and ending in dehydration. Respiratory alkalosis can occur from because of the increased respirations which cause a decrease in carbon dioxide or metabolic alkalosis is serum bicarbonate increases. 7.) Hyperparathyroidism parathyroid glands secrete PTH that helps the body maintain normal blood calcium levels. When the parathyroid gland(s) become overactive and secretes large amounts of PTH, the blood calcium levels increase. This can cause bone disease when calcium is reabsorbed from bone, bone density decreases which increases the risk of bone fractures. Renal failure can develop from such large levels of serum calcium because it impairs the kidney function by affecting the kidneys ability to filter the blood. Increased calcium levels increase blood pressure which puts more work on the heart. Vitamin D promotes calcium absorption in the gut and maintains adequate serum calcium levels for normal bone mineralization as well. 8.) When hydrogen ion levels increase, chemoreceptors stimulate the respiratory control center to increase the respiratory rate, which removes more carbon dioxide or acid from the body. This causes the body to retain more carbon dioxide and increases acid levels in the body. 9.) In a patient with low blood pressure, poor blow flow to the cells and increase in lactic acid, compensation by the lungs is inadequate because the lungs can only remove carbon dioxide, not other acids and they cannot produce bicarbonate, dialysis may be a treatment required to maintain the serum pH. The patient may experience rapid and deep respirations and the kidneys will excrete more acid and increase more bicarbonate absorption. 10.) It would be so dangerous because when breathing is suppressed the body holds CO2 in the body. The body tries to compensate by conserving HCO3 ions and eliminating H+ ions in the acidic urine. However if the kidneys have decreased function, then the H+ ions are not excreted through the urine.