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IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO.

5, MAY 2014 2407

Capacitively Loaded Circularly Polarized


Implantable Patch Antenna for ISM Band
Biomedical Applications
Changrong Liu, Student Member, IEEE, Yong-Xin Guo, Senior Member, IEEE, and Shaoqiu Xiao, Member, IEEE

AbstractA single-fed miniaturized circularly polarized and stored physiological data in biomedical telemetry [1], [2].
microstrip patch antenna is designed and experimentally demon- An inductive link is a short-range communication channel re-
strated for industrial-scientific-medical (2.42.48 GHz) biomedical quiring a coil antenna of the external device to be in close prox-
applications. The proposed antenna is designed by utilizing the
capacitive loading on the radiator. Compared with the initial imity to the IMD. On the other hand, communications via far-
topology of the proposed antenna, the so-called square patch field radio-frequency (RF) telemetry have advantages, such as
antenna with a center-square slot, the proposed method has the achieving longer distances and high data rates. In this connec-
advantage of good size reduction and good polarization purity. tion, research is oriented toward RF-linked implantable medical
The footprint of the proposed antenna is 10 10 1.27 mm . devices [2][20]. An implantable antenna is the key component
The simulated impedance, axial ratio, and radiation pattern
are studied and compared in two simulation models: cubic skin
of RF-linked IMDs, as many challenges arise when designing
phantom and Gustav voxel human body. The effect of different implantable antennas that need to meet requirements, such as
body phantoms is discussed to evaluate the sensitivity of the small size, wide operating bandwidth, sufficient radiation effi-
proposed antenna. The effect of coaxial cable is also discussed. ciency, and patient safety.
Two typical approaches to address the biocompatibility issue for In [2][4], the guidance of designing and testing an im-
practical applications are reported as well. The simulated and
plantable antenna is made in detail. Many research groups
measured impedance bandwidths in cubic skin phantom are 7.7%
and 10.2%, respectively. The performance of the communication [2][12] have widely utilized planar inverted-F antennas
link between the implanted CP antenna and the external antenna (PIFAs) to design implantable antennas because of the
is also presented. simple structure and compact size of PIFAs. In [13], an
Index TermsCircularly polarized antenna, communication implanted H-shaped cavity slot antenna embedded in the
link, implantable antenna, industrial scientific medical (ISM), link human arm at 2.45 GHz was proposed. A novel differentially
margin, small antenna, square patch antenna. fed dual-band implantable antenna was proposed in [14] for
a fully implantable neuro-microsystem. In [15], a low-profile
coplanar-waveguide (CPW)-fed implantable monopole antenna
I. INTRODUCTION was designed without superstrate. Open slots are introduced in

I MPLANTABLE medical devices (IMDs) have the capa- [16] to obtain a wide bandwidth and good size reduction for
bility to communicate wirelessly with an external device. designing implantable antennas. In [17], the effect of the human
These IMDs are receiving great attention for obtaining real time head on the transmission of RF signals in the medical implant
communications service (MICS) band (402405 MHz) between
the loop antennas that were placed in free space and implanted
Manuscript received July 16, 2013; revised February 04, 2014; accepted in the human head have been studied for medical applications.
February 05, 2014. Date of publication February 20, 2014; date of current In [18], a miniature conformal antenna was designed for the
version May 01, 2014. This work was supported in part by the National realization of a complete implantable device. Dipole antennas
Natural Science Foundation of China under Grants 61372012 and 61271028,
in part by the National Research Foundation, Singapore under the grant were studied for implantable antennas in [19], [21], and [22].
award number NRF-CRP10-2012-01, and in part by the Fundamental Various frequency bands are approved for medical implants.
Research Funds for the Central Universities. These bands include Medical Device Radio Communication
C. Liu is with National University of Singapore Suzhou Research Institute,
Suzhou, Jiangsu Province, China, 215123, the Department of Electrical and Service (MedRadio, 401406 MHz [3][11], [14][18]) and
Computer Engineering, National University of Singapore, Singapore 117576, industrial scientific medical (ISM) (433434.8 MHz [7], [14],
Singapore, and also with the School of Physical Electronics, University of [16]; 902928 MHz [7]; 2.42.48 GHz [5], [10][13], [16],
Electronic Science and Technology of China, Chengdu 610054, China (e-mail:
changrongliu@hotmail.com).
[18][20]; and 5.7255.875 GHz). The formerly known MICS
Y.-X. Guo is with the Department of Electrical and Computer Engineering, band (402405 MHz) is most commonly used for medical-im-
National University of Singapore, Singapore 117576, Singapore and also plant communications. Other frequency bands have also been
with the National University of Singapore Suzhou Research Institute, Suzhou,
Jiangsu Province 215123, China (e-mail: eleguoyx@nus.edu.sg).
suggested for implantable device biotelemetry. In [21] and
S. Xiao is with the School of Physical Electronics, University of Elec- [22], the capsule antenna and implantable antenna were de-
tronic Science and Technology of China, Chengdu 610054, China (e-mail: signed at the wireless medical telemetry services (WMTS)
xiaoshaoqiu@uestc.edu.cn).
Color versions of one or more of the figures in this paper are available online
band (13951400 MHz).
at http://ieeexplore.ieee.org. Communications via far-field RF-linked telemetry can be
Digital Object Identifier 10.1109/TAP.2014.2307341 hindered by the effects of multipath distortion. In view of

0018-926X 2014 IEEE. Personal use is permitted, but republication/redistribution requires IEEE permission.
See http://www.ieee.org/publications_standards/publications/rights/index.html for more information.
2408 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014

wireless-access applications, the circularly polarized radia-


tion property is desirable, since the reduction of multipath
and improvement of bit-error-rates can be achieved with the
use of circular polarization instead of linear polarization.
Few research groups have studied circularly polarized (CP)
implantable antennas. In [21], a conformal antenna for the
ingestible biotelemetric capsule system was studied. The offset
conformal meandered dipole was designed with polarization
diversity. A miniaturized cross dipole CP receiver antenna was
also presented.
In this paper, a novel miniaturized capacitively loaded CP
microstrip patch antenna is designed at the operating frequency
of 2.4 GHz. A method of capacitive loading on the radiator
was first used to design a CP implantable antenna. Details
of the antenna design and experiment results are presented Fig. 1. Geometry of an implantable patch antenna with a center square slot.
and discussed. The performance of the communication link
between the implanted CP antenna and the external antenna is
also presented.

II. CIRCULARLY POLARIZED IMPLANTABLE


PATCH ANTENNA DESIGN
To realize a small-size CP microstrip patch antenna, many
techniques have been developed. These include employing Fig. 2. Cubic skin phantom geometry for the design of an implantable antenna.
shorting pins/walls [23], cutting slots in the radiator patch
[24][32], or the ground plane [32][34], embedding tails
along the edge [35], loading metamaterial structures [36], or
transforming the patch antenna into a wire mesh and then
squeezing it in according fashion [37]. Besides these, induc-
tive/capacitive loading on patch [38], [39] is an effective way
to lower the resonance frequency. In [38], a novel capacitively
loaded microstrip loop resonator is developed with smaller size
and a higher Q factor. A miniaturized low-profile monopole
antenna was presented in [39], where the antenna achieved high
gain with omnidirectional and vertically polarization by using
the approach of inductive, top loaded, and inplane capacitive
couplings appropriately.
In this paper, we propose a compact implantable CP patch
antenna with capacitive loading to achieve better impedance
matching and capacitive coupling for effective size reduction. Fig. 3. Simulated reflection coefficients with different sizes of the center square
slot.
We first studied the characteristics of an implantable microstrip
patch antenna with a center square-slot, which is an initial
configuration and starting point of the proposed antenna. We
Fig. 2 shows the cubic skin phantom model. The distance from
then designed a compact capacitively loaded CP implantable
the side of the structure to the edge of the skin is 4 cm at both
patch antenna based on the study of the initial configuration
sides. The distance from the top of the superstrate to the edge
that the patch antenna would have good size reduction and
of the skin is 4 mm, and the distance from the bottom of the
good impedance matching with the suitable size of a center
substrate to the edge of the skin is 20 mm. The skin electrical
square slot.
properties ( 38, 1.44 S/m [40]) at 2.4 GHz were used
in the one-layer skin simulation model. The size of this cube is
A. Characteristics of an Implantable Microstrip Patch
. The Ansoft High Frequency Structure
Antenna With a Center Square Slot
Simulator (HFSS) was used for the design and analysis.
The initial topology of the implantable antenna shown in Fig. 3 shows the simulated reflection coefficients values with
Fig. 1 was designed on a two-layer Rogers 3010 substrate different lengths of the center square slot. We can see from
with dielectric constant of 10.2, a thickness of 25 mil for Fig. 3 that the resonant frequency of the regular microstrip patch
each layer, and a loss tangent of 0.003. The position antenna 0 mm) is about 4.23 GHz with a half wavelength
of feed is centered on in the -axis. Both the size of the in the multilayer substrate. The resonant frequency will shift
patch and ground are fixed to 9.5 9.5 mm and 10 10 mm, down from 4.23 to 3.07 GHz when is increased from 0 to
respectively. The feeding position is fixed at (3.7 mm, 0 mm). 6 mm. The impedance matching of the antenna with a center
LIU et al.: CAPACITIVELY LOADED CIRCULARLY POLARIZED IMPLANTABLE PATCH ANTENNA 2409

Fig. 4. Simulated real and imaginary input impedances with different sizes of
the center square slot.

square slot is better than that of a regular microstrip patch an-


tenna. From Fig. 4, the input impedance, including real and
imaginary parts of impedance, will increase quickly when is
increased from 0 to 6 mm.
As for typical compact microstrip patch antennas with center
square slots on the radiators operating in the free-space envi-
ronment, the excited patch surface current path will be longer
Fig. 5. Geometry of the proposed CP implantable antenna.
for the antenna with a center square slot than for the regular-size
square microstrip antenna. A patch with a center square slot of
increasing side length will make its minimum input impedance
inside the patch quickly increase. Therefore, an impedance
transformer was utilized to obtain good impedance matching
[29][31].
In this condition, the resonant frequency will shift down and
input impedance will increase with an increased length of the
center square slot. Caused by the initial large imaginary part of
input impedance, good impedance matching can be achieved
without an impedance transformer. The center square slot is
employed to have effective size reduction and good impedance
matching for an implantable microstrip patch antenna. Note that
the initial configuration of the implantable antenna has linear
polarization, and CP operation can be easily achieved by pro-
truding a pair of perturbation elements at the inner edge of the Fig. 6. Simulated reflection coefficient and AR of the proposed implantable
patch antenna with a center-square slot. antenna.

TABLE I
B. Compact-Implantable CP Microstrip Patch Antenna With DETAILED DIMENSIONS IN MILLIMETERS
Capacitive Loading
Based on the study of the initial topology that the patch
antenna would have good size reduction and good impedance
matching with a suitable size of a center square slot, a com-
pact capacitively loaded implantable CP patch antenna was
designed, as shown in Fig. 5. With the capacitive loading [38]
on the three sides of the patch, the patch size can be reduced
with fixed operation frequency. The capacitive couplings at
the center of the patch are to enhance the capacitive effect.
Moreover, slits 16 are employed to lengthen the current path,
thus lowering the resonant frequency. For simplicity, slits 14 fundamental resonant mode into two near-degenerate
have identical dimensions and slits 5 and 6 have identical orthogonal modes with equal amplitudes and 90 phase differ-
dimensions. CP operation was achieved (shown in Fig. 6) by ence. Table I shows the detailed dimensions. The cubic skin
protruding a pair of perturbation elements 1 and 2 with the phantom that is given in Fig. 2 is used to optimize the proposed
same dimensions of (shown in Fig. 5) to split the antenna.
2410 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014

Fig. 7. Three types of implantable microstrip patch antenna cases.

Fig. 9. Photograph of the fabricated implantable antenna

Fig. 8. Comparison reflection coefficients of different antenna cases.

TABLE II
SIMULATED RESULTS OF DIFFERENT ANTENNA CASES

Fig. 10. Illustration of the measurement setup.

III. MEASUREMENT RESULTS AND DISCUSSIONS


Fig. 6 shows the simulated impedance bandwidth that the
A. Reflection Coefficient and Communication Link
proposed antenna covers from 2.36 to 2.55 GHz ( 7.74%)
for a reflection coefficient of less than 10 dB and the AR Fig. 9 shows the fabricated antenna with its superstrate.
bandwidth that is covered from 2.44 to 2.48 GHz ( 1.63%) The antenna was measured by using a homogeneous mixture
for axial ratio (AR) 3 dB. The simulated results mean that solution proposed in [12]. The recipe is 58.2% deionized
the lowering in the center frequency can correspond to an water, 36.7% Triton X-100 (polyethylene glycol mono phenyl
antenna size reduction of about 72% by using the proposed ether) and 5.1% Diethylene glycol butyl ether (DGBE). In the
design in place of the regular implantable CP microstrip patch measurement, a similar volume of skin material was chosen to
design at a fixed operating frequency. The simulated peak demonstrate the design concept.
gain is 22 dBi at 2.45 GHz. The main polarization of this -parameters were carried out by Rohde & Schwarz ZVA50
proposed antenna is right-handed circular polarization (RHCP) vector network analyzer (VNA). Fig. 10 illustrates the commu-
with cross-polarization discrimination (XPD) 22 dB at the nication link of Tx and Rx. In this study, a dipole antenna is
main radiation direction. designed as an external antenna to demonstrate the polarization
For the purpose of analyzing the effect of capacitive loading, property of the proposed antenna. Fig. 11 shows the simulated
capacitive coupling and slits, antennas with different cases and measured -parameters. It can be seen from Fig. 11 that the
(shown in Fig. 7) were simulated and compared as shown measured of the proposed antenna is less than 10 dB in
in Fig. 8. Note that the CP property was not optimized for the frequency range from 2.41 to 2.67 GHz (10.2%). The reso-
simplicity. Table II lists the detailed simulated results. We nant frequency shift could be the air gap between the substrate
can see from Table II that the resonant frequency would shift and superstrate. Besides this, the difference could be due to
down with additional loading, while impedance matching and the fabrication tolerance. The dipole antenna has an impedance
impedance bandwidth remain nearly unchanged. bandwidth of 8.06% (2.382.58 GHz). The communication
LIU et al.: CAPACITIVELY LOADED CIRCULARLY POLARIZED IMPLANTABLE PATCH ANTENNA 2411

Fig. 11. Measured -parameters of the proposed antenna and external antenna. Fig. 13. Reflection coefficients of the proposed antenna simulated in one-layer
skin and voxel human body.

Fig. 14. Simulation models: (a) one-layer skin phantom; (b) three-layer tissue
phantom: case 1, and (c) three-layer tissue phantom: case 2.

Fig. 14 is simulated and compared to evaluate the effect of


implant positions of the implantable antenna. Note that three-
layer geometry consists of skin, fat, and muscle tissues. The
Fig. 12. The 3D Gustav voxel human body used for the implantable antenna dielectric properties of three tissues are taken from [40]. Based
design in a human chest.
on the simulated results shown in Fig. 15, it is seen that
the resonant frequency of the proposed antenna would have
link of the proposed antenna and the dipole antenna was mea- a significant shift to a higher frequency when the antenna was
sured when the dipole was placed at and 90 , respec- implanted in a fat layer.
tively. Note that the distance of Tx and Rx is 200 mm. The After discussing this in three-layer planer geometries, we
CP purity of the proposed antenna can be calculated by com- simulated the proposed antenna in the CST human body with
paring the communication link levels for two orthogonal po- different implant depths. The simulated results shown in Fig. 16
larizations. We can obtain good polarization purity at around also demonstrate that the implant depth could affect the
2.5 GHz . resonant frequency shift. Moreover, the polarization property
was affected in the human body, as can be seen in Fig. 16,
B. Comparative Analysis of Radiation Performance where the resonant frequency points of two orthogonal modes
To study the design in a realistic environment, the proposed are not close to each other. Better polarization
antenna is evaluated within the Gustav voxel human body. purity can be optimized by the turning pair of perturbation
Fig. 12 shows the 3D Gustav voxel human body used for the elements 1 and 2 to achieve near-degenerate orthogonal modes.
implantable design in a human chest. Numerical analyses are The total resonant frequency can be optimized by turning the
performed using the CST Microwave Suite [41]. Note that the resonant length. In this part, we just turned the perturbation
implant depth of the proposed antenna is 4 mm. elements 0.8 mm) and implant depth 3 mm)
The simulated impedance, axial ratio (AR) are studied and to obtain better polarization property, as shown in Fig. 17.
compared in two simulation models: cubic skin phantom and The frequency with good circular polarization is 2.46 GHz.
Gustav voxel human body. The respective results are shown in Fig. 18 shows the simulated radiation patterns of the proposed
Fig. 13. As shown in Fig. 13, the resonant frequency point is antenna in the human body at 2.46 GHz. The cross-polarization
shifted from 2.45 to 2.66 GHz. The reasons why the resonant discrimination (XPD) is over 20 dB at 2.46 GHz over a wide
frequency of the proposed antenna that was simulated in the range of the beam width (14 dB at ). The realized gain in
human body was shifted from 2.45 to 2.66 GHz could be: 1) the one-layer skin phantom is 22 dBi at 2.45 GHz, while the
the implant depth would affect the resonant frequency point; realized gain in the Gustav human body model is 20.4 dBi
2) the cubic skin phantom shown in Fig. 2 is not very accurate at 2.46 GHz. Table III shows the specific absorption rate (SAR)
for the 2.4-GHz ISM band application; 3) the asymmetry of distribution of the proposed antenna embedded in the human
the human body would affect the polarization property. The body. When the proposed antenna is assumed to deliver 1 W,
proposed antenna in the three simulation models shown in the simulated maximum 1-g and 10-g average SAR values are
2412 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014

Fig. 17. Performance of the proposed antenna with 0.8 mm, 3 mm


in the human body.

Fig. 15. Performances of the proposed antenna with different simulation


models: (a) reflection coefficients comparison and (b) AR comparison.
Fig. 18. Radiation patterns of the proposed antenna simulated in the voxel
human body at 2.46 GHz.

TABLE III
SIMULATED MAXIMUM SAR (INPUT POWER 1 W), AND MAXIMUM INPUT
POWER FOR SATISFYING THE SAR STANDARD IN THE HUMAN BODY

implanted in other positions, the proposed antenna is embedded


in four different body phantoms as below:
1) Phantom 1: skin phantom ;
2) Phantom 2 [19]: three-layered phantom
Fig. 16. Performance of the proposed antenna with different implant depths. ;
3) Phantom 3 [18]: cylinder muscle phantom
;
213 and 26.6 W/kg, respectively. Therefore, the allowed trans- 4) Phantom 4 [20]: scalp phantom .
mitter power values are 7.51 and 75.2 mW to satisfy the 1-g and Fig. 19 shows the detailed body phantoms (2, 3, and 4).
10-g SAR regulation, respectively [42], [43]. In [44], the output Fig. 20 reports the simulated results with different phantoms.
power of the transmitter is 14 dBm ( 0.04 mW), which is The resonant frequencies of 2.45, 2.60, 2.40, and 2.40 GHz
much lower than the allowed transmitter power. SAR should were found for the skin, three-layered, muscle, and scalp
not be a concern in this condition. phantoms, respectively. The resonant frequency shift is mainly
due to the change of relative dielectric constant, especially in
C. Effect of Different Phantoms the three-layered phantom as the relative dielectric constant of
To evaluate the sensitivity of the proposed antenna, whether fat is very small compared with other tissues. Similar resonant
it could be used in other specific biomedical applications or be frequencies are obtained between muscle and scalp phantoms.
LIU et al.: CAPACITIVELY LOADED CIRCULARLY POLARIZED IMPLANTABLE PATCH ANTENNA 2413

Fig. 19. Cross view of different body phantoms: (a) the three-layered phantom,
(b) the cylinder muscle phantom, and (c) the scalp phantom.

Fig. 21. Description of different models: (a) case 1, (b) case 2, (c) case 3, and
(d) case 4.

Fig. 20. Performances of the proposed antenna with different dielectric prop-
erties: (a) reflection coefficients comparison and (b) AR comparison.

Moreover, the proposed antenna embedded in muscle and scalp


phantoms can still maintain good impedance matching and
circular polarization, as shown in Fig. 20(b). The results show
that the proposed antenna can be optimized for other specific Fig. 22. Performances of the proposed antenna with different cases: (a) reflec-
tion coefficients comparison and (b) AR comparison.
biomedical applications.

D. Effect of Coaxial Cable Case 4) The whole implant device consists of an im-
Referring to [18], four different simulation models are listed plantable antenna, biocompatible housing, and
in Fig. 21 to evaluate the feeding coaxial cable effect. other electronics, as shown in Fig. 21(d); the other
Case 1) The coaxial cable is in direct contact with the skin, electronics are set as perfect electric conductors
as shown in Fig. 21(a). (PEC) in HFSS.
Case 2) A biocompatible material (Silastic MDX4-4210 Simulated reflection coefficients for the four different cases
biomedical-grade base elastomer ( 3.3, are shown in Fig. 22. The results indicate that small coupling
0.01 S/m, thickness 0.05 mm) [45] shell sur- exists between the currents flowing on the external metal of the
rounds the cable and ground plane, as shown in cable and the body phantom [18]. The impedance matching of
Fig. 21(b). the proposed antenna in all of the simulation models is good. AR
Case 3) The length of coaxial cable is reduced to 1 mm, as performance in case 4 means that the packaging of the entire im-
shown in Fig. 21(c). plant system would have a little effect on the polarization prop-
2414 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014

TABLE IV
PERFORMANCE COMPARISONS FOR FOUR TYPES OF SIMULATION MODELS
AT 2.45 GHz

Fig. 23. Two approaches to address the biocompatibility issue for practical ap-
plications: (a) proposed antenna with biocompatible material and (b) proposed
antenna with encased biocompatible material.

erty. Table IV shows the radiation performance of the proposed


antenna in the different models. The realized gain was improved
with packaging, but AR and XPD were degraded. The proposed
antenna can be further optimized for final real applications.
The measurement setup shown in Fig. 10 did not consider the
effect of reflected signals. It should be more accurate if the pro-
posed antenna is tested in the chamber environment as reported
in [20]. After the discussions about the cables effect, we think
that the test has demonstrated the antennas performance.
Fig. 24. Performances of the proposed antenna with different materials: (a)
reflection coefficients comparison and (b) AR comparison.
E. Biocompatible Insulation
In this design, Rogers RO3010 is used as a substrate and su-
perstrate. However, implantable antennas need to be biocompat- material should be taken into consideration for practical antenna
ible with the surrounding tissue, since Rogers RO3010 is not a designs [4], [46]. We can see from Fig. 25 that the thinner the
biocompatible material. There are two typical approaches to ad- encased biocompatible material is, the less the frequency shifts.
dress the biocompatibility issue for practical applications. One When the thickness of encased biocompatible material is 0.05
is to design antennas directly on biocompatible materials, such or 0.01 mm, good polarization purity can also be achieved even
as macor, teflon, and ceramic alumina [4]; the other one is to en- if the resonant frequency has a little shift. The proposed antenna
case the implantable antenna with a thin layer of low-loss bio- with an encased biocompatible coating needs to be reoptimized
compatible coating [45]. This discussion is based on the simu- to enable ISM band operation.
lation model shown in Fig. 2.
For the first approach [shown in Fig. 23(a)], Rogers RO3010 IV. COMMUNICATION LINK
10.2) is replaced by biocompatible alumina ce- Assuming far-field communication, the link power budget
ramic 9.8). Fig. 24 shows that the resonant frequency is can be described in terms of [13]
shifted from 2.45 to 2.5 GHz. This is reasonable, since the rel-
ative dielectric constant of alumina ceramic is a little smaller Link margin dB Link Required
than that of RO3010. For further realistic applications, biocom-
patible metals, such as silver palladium (Ag/Pd), can be used in- (1)
stead of copper to achieve the antenna structure on the biocom-
patible materials. In further study, the proposed antenna with where is the transmit power, is the transmit antenna gain,
biocompatible materials can be optimized to the desired reso- is the path loss (free space), is the receive antenna gain,
nant frequency. and is the noise power density.
The other one is to encase the proposed implantable antenna According to the free-space reduction in signal strength with
with a thin layer of low-loss biocompatible coating as shown the distance between the transmitter and receiver, the path loss
in Fig. 23(b). A biocompatible material Silastic MDX4-4210 can be calculated as
biomedical-grade base elastomer ( 3.3, 0.01 S/m) [45]
is used here to evaluate the coating effect. (2)
Note that the thickness of encased biocompatible material
may affect the antenna performance, and encased biocompatible where is the distance between the Tx and Rx.
LIU et al.: CAPACITIVELY LOADED CIRCULARLY POLARIZED IMPLANTABLE PATCH ANTENNA 2415

TABLE V
PARAMETERS OF THE LINK BUDGET

Fig. 25. Performances of the proposed antenna with/without encasing silicone:


(a) reflection coefficients comparison and (b) AR comparison.

Fig. 26. Simulated link margin of the proposed CP implantable antenna.

Consider the impedance mismatch loss


V. CONCLUSION
(3)
This paper presents a compact implantable CP microstrip
where is the appropriate reflection coefficient. patch antenna for the 2.45-GHz ISM band. First, the character-
As for the proposed antenna, note that the antenna operates istic of an implantable microstrip patch antenna with a center
at 2.46 GHz with good circular polarization (shown in Fig. 17), square slot was studied. A center square slot is employed to
while at 2.46 GHz is 8.3 dB. The impedance mis- have effective size reduction and good impedance matching
match loss of the transmitter and implantable antenna could not for the implantable microstrip patch antenna. Second, a com-
be neglected. The impedance mismatch loss is 0.695 dB at pact capacitively loaded CP implantable patch antenna was
2.46 GHz. designed. The simulated impedance, AR, and radiation pattern
For the Rx antenna, we could consider one exterior linear- are studied and compared in two simulation models: cubic skin
polarized (LP) dipole antenna with a realized gain of 2.15 dBi phantom in HFSS and Gustav voxel human body in CST. The
and another exterior CP antenna with a realized gain of 2.15 cubic skin phantom model was used for the numerical and ex-
dBi. Note that the Tx antenna has circular polarization, and the perimental analysis. This simple model can significantly reduce
polarization mismatching losses are 0 dB and 3 dB when the optimization time. After the proposed antenna in different
the Rx antenna has circular polarization and linear polarization, body phantoms is discussed, the proposed antenna can still
respectively. The impedance mismatch loss of the receiver and contain good impedance matching. Resonant frequency shift
Rx antenna is neglected in this condition. The link margin can and polarization property can be re-optimized with specific
be calculated by using the parameters listed in Table V [13]. real biomedical applications. Finally, the proposed antenna was
Fig. 26 shows the detailed link margin with distance. To make embedded in a Gustav voxel human body to study the design
wireless communication possible, the link margin should be in a realistic environment. The proposed antenna can achieve
better than 0 dB. According to the simulated results, it is pos- good polarization purity by turning the perturbation elements
sible to use wireless communications when the distance of Rx and implant depth, as shown in Fig. 17. In addition, the SAR
and Tx is less than 10 m when the Rx antenna is with CP and distribution and radiation patterns are presented. The proposed
less than 7 m when the Rx antenna is with LP. antenna was measured in a one-layer skin environment, and
2416 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014

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[36] Y. Dong, H. Toyao, and T. Itoh, Compact circularly-polarized patch Yong-Xin Guo (SM05) received the B.Eng. and
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55, no. 7, pp. 14221426, Mar. 2013. of Hong Kong, Hong Kong, China, in 2001.
[38] J. H. Song and M. J. Lancaster, Capactively loaded microstrip loop He was with the Institute for Infocomm Research,
resonator, Electron. Lett., vol. 30, no. 18, pp. 14941495, 1994. Singapore, as a Research Scientist, from 2001 to
[39] J. Oh and K. Sarabandi, Low profile, miniaturized, inductively cou- 2009. He joined the Department of Electrical and
pled capacitively loaded monopole antenna, IEEE Trans. Antennas Computer Engineering (ECE), National University
Propag., vol. 60, no. 3, pp. 12061213, Mar. 2012. of Singapore (NUS), as an Assistant Professor in
[40] S. Gabriel, R. W. Lau, and C. Gabriel, The dielectric properties of bi- 2009 and was promoted to Associate Professor with tenure in 2013. He is also
ological tissues, Phys. Med. Biol. pp. 22312293, Oct. 2004. [Online]. Director of Center for Microwave and Radio Frequency at the Department
Available: http://niremf.ifac.cnr.it/tissprop/, (1996) of Electrical and Computer Engineering, NUS. Concurrently, he is a Senior
[41] CST Microwave Suite Ver. 2012.08 CST Voxel human body model, Investigator at the National University of Singapore Suzhou Research Institute
2013. [Online]. Available: http://www.cst.com (NUSRI), Suzhou, China, and Director of Center of Advanced Microelectronic
[42] IEEE Standard for Safety Levels With Respect to Human Exposure to Devices, NUSRI. He has authored or coauthored 137 international journal pa-
Radio Frequency Electromagnetic Fields, 3 kHz to 300 GHz, IEEE pers and 152 international conference papers. So far, his publications have been
Standard C95.1-1999, 1999. cited more than 1189 times and the H-index is 22 (source: Scopus). He holds
[43] IEEE Standard for Safety Levels With Respect to Human Exposure to one granted U.S. patent and four filed U.S. provisional patents. His current
Radiofrequency Electromagnetic Fields, 3 kHz to 300 GHz, IEEE Stan- research interests include microstrip antennas for wireless communications,
dard C95.1-2005, 2005. implantable/wearable antennas and body channel modeling for biomedical
[44] J. Jung, S. Zhu, P. Liu, Y. E. Chen, and D. Heo, 22-pJ/bit applications, wireless power and RF energy harvesting, microwave circuits,
energy-efficient 2.4-GHz implantable OOK transmitter for wire- and monolithic-microwave integrated-circuit modeling and design.
less biotelemetry systems: In vitro experiments using rat skin-mimic, Dr. Guo is the General Chair for 2015 IEEE MTT-S International Microwave
IEEE Trans. Microw. Theory Tech., vol. 58, no. 12, pp. 41024111, Workshop Series on Advanced Materials and Processes for RF and THz Appli-
Dec. 2010. cations (IMWS-AMP 2015), Suzhou, China. He was the General Chair for IEEE
[45] T. Karacolak, R. Cooper, J. Butler, S. Fisher, and E. Topsakal, In Vivo MTT-S International Microwave Workshop Series 2013 on RF and Wireless
verification of implantable antennas using rats as model animal, IEEE Technologies for biomedical and Healthcare Applications (IMWS-Bio 2013)
Antennas Wireless Propag Lett., vol. 9, pp. 334337, 2010. in Singapore. He served as a Technical Program Committee (TPC) Co-Chair
[46] F. Merli, B. Fuchs, J. R. Mosig, and A. K. Skrivervik, The effect for the IEEE International Symposium on Radio Frequency Integration Tech-
of insulating layers on the performance of implanted antennas, IEEE nology (RFIT2009). He has been a TPC member and session chair for numerous
Trans. Antennas Propag., vol. 59, no. 1, pp. 2131, Jan. 2011. conferences and workshops. He has also been on the editorial boards of the In-
ternational Journal of RF and Microwave Computer-Aided Engineering, and
International Journal of Microwave Science and Technology. He is serving as an
Associate Editor for IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS
(AWPL). He was a recipient of the Young Investigator Award in 2009, National
University of Singapore. He received the 2013 Raj Mittra Travel Grant Senior
Researcher Award.

Changrong Liu (S12) was born in Jiangsu, China,


in 1986. He received the B.E degree in electronic
information science and technology and the M.E. Shaoqiu Xiao (M05) received Ph.D. degree in elec-
degree in radio physics from University of Elec- tromagnetic field and microwave engineering from
tronic Science and Technology of China (UESTC), the University of Electronic Science and Technology
Chengdu, China, in 2008 and 2011, respectively, of China (UESTC), Chengdu, China, in 2003.
where he is currently pursuing the Ph.D. degree in In 2004, he joined UESTC as an Assistant
radio physics. Professor. From 2004 to 2006, he worked for the
From 2010 to 2011, he was a Visiting Student in the Wireless Communications Laboratory, National
Department of Electrical and Computer Engineering, Institute of Information and Communications Tech-
NUS, Singapore. Since 2012, he has been a Visiting nology of Japan (NICT), Singapore, as a Researcher
Scholar at the National University of Singapore, Singapore. His main research with the focus on the planar antenna and smart an-
interests include LTCC-based millimeter-wave antenna array design; circularly tenna design and optimization. From 2006 to 2010,
polarized beam-steering antenna array; and implantable antennas for biomedical he worked for UESTC as an Associate Professor and now he is working for
applications, including wireless data telemetry and power transfer. UESTC as a Professor. His current research interests include planar antenna and
Mr. Liu is a reviewer of IEEE ANTENNAS AND WIRELESS PROPAGATION phased array, microwave passive circuits, and time-reversal electromagnetics.
LETTERS. He was the recipient of the Best Student Paper Award at the 2011 He has authored/coauthored more than 160 technical journals, conference
National Conference on Microwave and Millimeter Waves, Qingdao, China. papers, books, and book chapters.

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