Академический Документы
Профессиональный Документы
Культура Документы
AbstractA single-fed miniaturized circularly polarized and stored physiological data in biomedical telemetry [1], [2].
microstrip patch antenna is designed and experimentally demon- An inductive link is a short-range communication channel re-
strated for industrial-scientific-medical (2.42.48 GHz) biomedical quiring a coil antenna of the external device to be in close prox-
applications. The proposed antenna is designed by utilizing the
capacitive loading on the radiator. Compared with the initial imity to the IMD. On the other hand, communications via far-
topology of the proposed antenna, the so-called square patch field radio-frequency (RF) telemetry have advantages, such as
antenna with a center-square slot, the proposed method has the achieving longer distances and high data rates. In this connec-
advantage of good size reduction and good polarization purity. tion, research is oriented toward RF-linked implantable medical
The footprint of the proposed antenna is 10 10 1.27 mm . devices [2][20]. An implantable antenna is the key component
The simulated impedance, axial ratio, and radiation pattern
are studied and compared in two simulation models: cubic skin
of RF-linked IMDs, as many challenges arise when designing
phantom and Gustav voxel human body. The effect of different implantable antennas that need to meet requirements, such as
body phantoms is discussed to evaluate the sensitivity of the small size, wide operating bandwidth, sufficient radiation effi-
proposed antenna. The effect of coaxial cable is also discussed. ciency, and patient safety.
Two typical approaches to address the biocompatibility issue for In [2][4], the guidance of designing and testing an im-
practical applications are reported as well. The simulated and
plantable antenna is made in detail. Many research groups
measured impedance bandwidths in cubic skin phantom are 7.7%
and 10.2%, respectively. The performance of the communication [2][12] have widely utilized planar inverted-F antennas
link between the implanted CP antenna and the external antenna (PIFAs) to design implantable antennas because of the
is also presented. simple structure and compact size of PIFAs. In [13], an
Index TermsCircularly polarized antenna, communication implanted H-shaped cavity slot antenna embedded in the
link, implantable antenna, industrial scientific medical (ISM), link human arm at 2.45 GHz was proposed. A novel differentially
margin, small antenna, square patch antenna. fed dual-band implantable antenna was proposed in [14] for
a fully implantable neuro-microsystem. In [15], a low-profile
coplanar-waveguide (CPW)-fed implantable monopole antenna
I. INTRODUCTION was designed without superstrate. Open slots are introduced in
I MPLANTABLE medical devices (IMDs) have the capa- [16] to obtain a wide bandwidth and good size reduction for
bility to communicate wirelessly with an external device. designing implantable antennas. In [17], the effect of the human
These IMDs are receiving great attention for obtaining real time head on the transmission of RF signals in the medical implant
communications service (MICS) band (402405 MHz) between
the loop antennas that were placed in free space and implanted
Manuscript received July 16, 2013; revised February 04, 2014; accepted in the human head have been studied for medical applications.
February 05, 2014. Date of publication February 20, 2014; date of current In [18], a miniature conformal antenna was designed for the
version May 01, 2014. This work was supported in part by the National realization of a complete implantable device. Dipole antennas
Natural Science Foundation of China under Grants 61372012 and 61271028,
in part by the National Research Foundation, Singapore under the grant were studied for implantable antennas in [19], [21], and [22].
award number NRF-CRP10-2012-01, and in part by the Fundamental Various frequency bands are approved for medical implants.
Research Funds for the Central Universities. These bands include Medical Device Radio Communication
C. Liu is with National University of Singapore Suzhou Research Institute,
Suzhou, Jiangsu Province, China, 215123, the Department of Electrical and Service (MedRadio, 401406 MHz [3][11], [14][18]) and
Computer Engineering, National University of Singapore, Singapore 117576, industrial scientific medical (ISM) (433434.8 MHz [7], [14],
Singapore, and also with the School of Physical Electronics, University of [16]; 902928 MHz [7]; 2.42.48 GHz [5], [10][13], [16],
Electronic Science and Technology of China, Chengdu 610054, China (e-mail:
changrongliu@hotmail.com).
[18][20]; and 5.7255.875 GHz). The formerly known MICS
Y.-X. Guo is with the Department of Electrical and Computer Engineering, band (402405 MHz) is most commonly used for medical-im-
National University of Singapore, Singapore 117576, Singapore and also plant communications. Other frequency bands have also been
with the National University of Singapore Suzhou Research Institute, Suzhou,
Jiangsu Province 215123, China (e-mail: eleguoyx@nus.edu.sg).
suggested for implantable device biotelemetry. In [21] and
S. Xiao is with the School of Physical Electronics, University of Elec- [22], the capsule antenna and implantable antenna were de-
tronic Science and Technology of China, Chengdu 610054, China (e-mail: signed at the wireless medical telemetry services (WMTS)
xiaoshaoqiu@uestc.edu.cn).
Color versions of one or more of the figures in this paper are available online
band (13951400 MHz).
at http://ieeexplore.ieee.org. Communications via far-field RF-linked telemetry can be
Digital Object Identifier 10.1109/TAP.2014.2307341 hindered by the effects of multipath distortion. In view of
0018-926X 2014 IEEE. Personal use is permitted, but republication/redistribution requires IEEE permission.
See http://www.ieee.org/publications_standards/publications/rights/index.html for more information.
2408 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014
Fig. 4. Simulated real and imaginary input impedances with different sizes of
the center square slot.
TABLE I
B. Compact-Implantable CP Microstrip Patch Antenna With DETAILED DIMENSIONS IN MILLIMETERS
Capacitive Loading
Based on the study of the initial topology that the patch
antenna would have good size reduction and good impedance
matching with a suitable size of a center square slot, a com-
pact capacitively loaded implantable CP patch antenna was
designed, as shown in Fig. 5. With the capacitive loading [38]
on the three sides of the patch, the patch size can be reduced
with fixed operation frequency. The capacitive couplings at
the center of the patch are to enhance the capacitive effect.
Moreover, slits 16 are employed to lengthen the current path,
thus lowering the resonant frequency. For simplicity, slits 14 fundamental resonant mode into two near-degenerate
have identical dimensions and slits 5 and 6 have identical orthogonal modes with equal amplitudes and 90 phase differ-
dimensions. CP operation was achieved (shown in Fig. 6) by ence. Table I shows the detailed dimensions. The cubic skin
protruding a pair of perturbation elements 1 and 2 with the phantom that is given in Fig. 2 is used to optimize the proposed
same dimensions of (shown in Fig. 5) to split the antenna.
2410 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014
TABLE II
SIMULATED RESULTS OF DIFFERENT ANTENNA CASES
Fig. 11. Measured -parameters of the proposed antenna and external antenna. Fig. 13. Reflection coefficients of the proposed antenna simulated in one-layer
skin and voxel human body.
Fig. 14. Simulation models: (a) one-layer skin phantom; (b) three-layer tissue
phantom: case 1, and (c) three-layer tissue phantom: case 2.
TABLE III
SIMULATED MAXIMUM SAR (INPUT POWER 1 W), AND MAXIMUM INPUT
POWER FOR SATISFYING THE SAR STANDARD IN THE HUMAN BODY
Fig. 19. Cross view of different body phantoms: (a) the three-layered phantom,
(b) the cylinder muscle phantom, and (c) the scalp phantom.
Fig. 21. Description of different models: (a) case 1, (b) case 2, (c) case 3, and
(d) case 4.
Fig. 20. Performances of the proposed antenna with different dielectric prop-
erties: (a) reflection coefficients comparison and (b) AR comparison.
D. Effect of Coaxial Cable Case 4) The whole implant device consists of an im-
Referring to [18], four different simulation models are listed plantable antenna, biocompatible housing, and
in Fig. 21 to evaluate the feeding coaxial cable effect. other electronics, as shown in Fig. 21(d); the other
Case 1) The coaxial cable is in direct contact with the skin, electronics are set as perfect electric conductors
as shown in Fig. 21(a). (PEC) in HFSS.
Case 2) A biocompatible material (Silastic MDX4-4210 Simulated reflection coefficients for the four different cases
biomedical-grade base elastomer ( 3.3, are shown in Fig. 22. The results indicate that small coupling
0.01 S/m, thickness 0.05 mm) [45] shell sur- exists between the currents flowing on the external metal of the
rounds the cable and ground plane, as shown in cable and the body phantom [18]. The impedance matching of
Fig. 21(b). the proposed antenna in all of the simulation models is good. AR
Case 3) The length of coaxial cable is reduced to 1 mm, as performance in case 4 means that the packaging of the entire im-
shown in Fig. 21(c). plant system would have a little effect on the polarization prop-
2414 IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 62, NO. 5, MAY 2014
TABLE IV
PERFORMANCE COMPARISONS FOR FOUR TYPES OF SIMULATION MODELS
AT 2.45 GHz
Fig. 23. Two approaches to address the biocompatibility issue for practical ap-
plications: (a) proposed antenna with biocompatible material and (b) proposed
antenna with encased biocompatible material.
TABLE V
PARAMETERS OF THE LINK BUDGET
the measured results showed good agreement with the simu- [13] W. Xia, K. Saito, M. Takahashi, and K. Ito, Performances of an im-
lated results, including impedance bandwidth and polarization planted cavity slot antenna embedded in the human arm, IEEE Trans.
Antennas Propag., vol. 57, no. 4, pp. 894899, Apr. 2009.
property. [14] Z. Duan, Y. X. Guo, R. F. Xue, M. Je, and D. L. Kwong, Differen-
The feeding cable effect was discussed, as the measurement tially-fed dual-band implantable antenna for biomedical applications,
setup is unrealistic for real applications. Fig. 21 presents four IEEE Trans. Antennas Propag., vol. 60, no. 12, pp. 55875595, Dec.
2012.
different simulation models to evaluate the feeding coaxial [15] T. F. Chien, C.-M. Cheng, H.-C. Yang, J.-W. Jiang, and C.-H. Luo,
cable effect and packaging problem. The results indicate small Development of nonsuperstrate implantable low-profile CPW-fed ce-
coupling between the cable and the body phantom. Impedance ramic antennas, IEEE Antennas Wireless Propag. Lett., vol. 9, pp.
599602, 2010.
matching is good in all of the simulation models. AR perfor- [16] L. J. Xu, Y. X. Guo, and W. Wu, Dual-band implantable antenna with
mance in case 4 means that the packaging of the entire implant open-end slots on ground, IEEE Antennas Wireless Propag. Lett., vol.
system would have little effect on the polarization property. 11, pp. 15641567, 2012.
[17] Z. N. Chen, G. C. Liu, and T. S. P. See, Transmission of RF signals
The realized gain was improved with packaging, but AR and between MICS loop antennas in free space and implanted in the human
XPD should be optimized in further research. head, IEEE Trans. Antennas Propag., vol. 57, no. 6, pp. 18501854,
The biocompatibility issue should be addressed for im- Jun. 2009.
[18] F. Merli, L. Bolomey, J.-F. Zrcher, G. Corradini, E. Meurville, and
plantable antennas. Two typical approaches for practical A. K. Skrivervik, Design, realization and measurements of a minia-
applications were studied and compared. In the first approach, ture antenna for implantable wireless communication systems, IEEE
the needed operation frequency can be easily optimized. In the Trans. Antennas Propag., vol. 59, no. 10, pp. 35443555, Oct. 2011.
[19] H. Mizuno, K. Ito, M. Takahashi, and K. Saito, A helical folded dipole
other approach, the thickness of the biocompatible material for antenna for implantable communication devices, in Proc. IEEE An-
the coating would affect the resonant frequency and AR of the tennas Propag. Soc. Int. Symp., 2010, pp. 14.
proposed antenna. Thus, we should consider the thickness of the [20] R. Warty, M. R. Tofighi, U. Kawoos, and A. Rosen, Characterization
of implantable antennas for intracranial pressure monitoring: Reflec-
coating when using the second approach for biocompatibility. tion by and transmission through a scalp phantom, IEEE Trans. Mi-
Finally, the link margin for the proposed antenna and exte- crow. Theory Tech., vol. 56, no. 10, pp. 23662376, Oct. 2008.
rior CP/LP antennas is characterized to demonstrate its wireless [21] P. M. Izdebski, H. Rajagopalan, and Y. Rahmat-Samii, Conformal
ingestible capsule antenna: A novel chandelier meandered design,
communication ability. IEEE Trans. Antennas Propag., vol. 57, no. 10, pp. 900909, Apr.
2009.
[22] K. Gosalia, M. S. Humayun, and G. Lazzi, Impedance matching and
REFERENCES implementation of planar space-filling dipoles as intraocular implanted
[1] P. S. Hall and Y. Hao, Antennas and Propagation for Body-Centric antennas in a retinal prosthesis, IEEE Trans. Antennas Propag., vol.
Wireless Communications. Norwell, MA, USA: Artech House, 2006. 53, no. 8, pp. 23652373, Aug. 2005.
[2] A. Kiourti and K. S. Nikita, A review of implantable patch antennas [23] H. Wong, K. K. So, K. B. Ng, K. M. Luk, C. H. Chan, and Q. Xue,
for biomedical telemetry: Challenges and solutions, IEEE Antennas Virtually shorted patch antenna for circular polarization, IEEE An-
Propag. Mag., vol. 54, no. 3, pp. 210228, Jun. 2012. tennas Wireless Propag. Lett., vol. 9, pp. 12131216, 2010.
[3] J. Kim and Y. Rahmat-Samii, Implanted antennas inside a human [24] W. S. Chen, C. K. Wu, and K. L. Wong, Novel compact circularly
body: Simulations, designs, characterizations, IEEE Trans. Microw. polarized square microstrip antenna, IEEE Trans. Antennas Propag.,
Theory Tech., vol. 52, no. 8, pp. 19341943, Aug. 2004. vol. 49, no. 3, pp. 340342, Mar. 2001.
[4] P. Soontornpipit, C. M. Furse, and Y. C. Chung, Design of im- [25] K. Y. Lam, K.-M. Luk, K. F. Lee, H. Wong, and K. B. Ng, Small
plantable microstrip antennas for communication with medical circularly polarized U-slot wideband patch antenna, IEEE Antennas
implants, IEEE Trans. Microw. Theory Tech., vol. 52, no. 8, pp. Wireless Propag. Lett., vol. 10, pp. 8790, 2011.
19441951, Aug. 2004. [26] H. Iwasaki, A circularly polarized small-size microstrip antenna
[5] T. Karacolak, A. Hood, and E. Topsakal, Design of a dual-band im- with a cross slot, IEEE Trans. Antennas Propag., vol. 44, no. 10, pp.
plantable antenna and development of skin mimicking gels for contin- 13991401, Oct. 1996.
uous glucose monitoring, IEEE Trans. Microw. Theory Tech., vol. 56, [27] M. Elsdon, A. Sambell, S. C. Gao, and Y. Qin, Compact circular
no. 4, pp. 10011008, Apr. 2008. polarised patch antenna with relaxed manufacturing tolerance and
[6] N. Cho, T. Roh, J. Bae, and H.-J. Yoo, A planar MICS band an- improved axial ratio bandwidth, Electron. Lett., vol. 39, no. 18, pp.
tenna combined with a body channel communication electrode for body 12961298, Sep. 2003.
sensor network, IEEE Trans. Microw. Theory Tech., vol. 57, no. 10, [28] Nasimuddin, X. Qing, and Z. N. Chen, Compact asymmetric-slit
pp. 25152522, Oct. 2009. microstrip antennas for circular polarization, IEEE Trans. Antennas
[7] A. Kiourti and K. S. Nikita, Miniature scalp-implantable antennas for Propag., vol. 59, no. 1, pp. 285288, Jan. 2011.
telemetry in the MICS and ISM bands: Design, safety considerations [29] K. L. Wong and Y. F. Lin, Circularly polarised microstrip antenna
and link budget analysis, IEEE Trans. Antennas Propag., vol. 60, no. with a tuning stub, Electron. Lett., vol. 34, no. 9, pp. 831832, Apr.
8, pp. 35683575, Aug. 2012. 1998.
[8] C.-M. Lee, T.-C. Yo, F.-J. Huang, and C.-H. Luo, Dual-resonant [30] H.-M. Chen and K.-L. Wong, On the circular polarization operation
-shape with double L-strips PIFA for implantable biotelemetry, of annular-ring microstrip antennas, IEEE Trans. Antennas Propag.,
Electron. Lett., vol. 44, no. 14, pp. 837838, Jul. 3, 2008. vol. 47, no. 8, pp. 12891292, Aug. 1999.
[9] W.-C. Liu, S.-H. Chen, and C.-M. Wu, Bandwidth enhancement and [31] C. Liu, S. Xiao, Y. X. Guo, Y.-Y. Bai, M.-C. Tang, and B.-Z.
size reduction of an implantable PIFA antenna for biotelemetry de- Wang, Compact circularly-polarized microstrip antenna with sym-
vices, Microw. Opt. Technol. Lett., vol. 51, pp. 755757, Mar. 2009. metric-slit, Electron. Lett., vol. 48, no. 4, pp. 195196, Feb. 2012.
[10] C. J. Sachez-Fernadez, O. Quevedo-Teruel, J. Requena-Carrio, L. [32] J.-S. Row and C.-Y. Ai, Compact design of single-feed circularly
Incla-Sachez, and E. Rajo-Iglesias, Dual-band microstrip patch polarised microstrip antenna, Electron. Lett., vol. 40, no. 18, pp.
antenna based on short-circuited ring and spiral resonators for im- 10931094, Sep. 2004.
plantable medical devices, IET Microw., Antennas Propag., vol. 4, [33] H.-D. Chen, Compact circularly polarized microstrip antenna with
no. 8, pp. 10481055, 2010. slotted ground plane, Electron. Lett., vol. 38, no. 13, pp. 616617,
[11] C. Liu, Y. X. Guo, and S. Xiao, Compact dual-band antenna for im- 2002.
plantable devices, IEEE Antennas Wireless Propag. Lett., vol. 11, pp. [34] X. L. Bao and M. J. Ammann, Dual-frequency circularly-polarized
15081511, 2012. patch antenna with compact size and small frequency ratio, IEEE
[12] T. Yilmaz, T. Karacolak, and E. Topsakal, Characterization and Trans. Antennas Propag., vol. 55, no. 7, pp. 21042107, Jul. 2007.
testing of a skin mimicking material for implantable antennas oper- [35] X. Tang, K.-L. Lau, Q. Xue, and Y. Long, Design of small circularly
ation at ISM band (2.4 GHz2.48 GHz), IEEE Antennas Wireless polarized patch antenna, IEEE Antennas Wireless Propag. Lett., vol.
Propag. Lett., vol. 7, pp. 418420, 2008. 9, pp. 728731, 2010.
LIU et al.: CAPACITIVELY LOADED CIRCULARLY POLARIZED IMPLANTABLE PATCH ANTENNA 2417
[36] Y. Dong, H. Toyao, and T. Itoh, Compact circularly-polarized patch Yong-Xin Guo (SM05) received the B.Eng. and
antenna loaded with metamaterial structures, IEEE Trans. Antennas M.Eng. degrees in electronic engineering from Nan-
Propag., vol. 59, no. 11, pp. 43294333, Nov. 2012. jing University of Science and Technology, Nanjing,
[37] J. Oh and K. Sarabandi, A topology-based miniaturization of circu- China, in 1992 and 1995, respectively, and the Ph.D.
larly polarized patch antennas, IEEE Trans. Antennas Propag., vol. degree in electronic engineering from City University
55, no. 7, pp. 14221426, Mar. 2013. of Hong Kong, Hong Kong, China, in 2001.
[38] J. H. Song and M. J. Lancaster, Capactively loaded microstrip loop He was with the Institute for Infocomm Research,
resonator, Electron. Lett., vol. 30, no. 18, pp. 14941495, 1994. Singapore, as a Research Scientist, from 2001 to
[39] J. Oh and K. Sarabandi, Low profile, miniaturized, inductively cou- 2009. He joined the Department of Electrical and
pled capacitively loaded monopole antenna, IEEE Trans. Antennas Computer Engineering (ECE), National University
Propag., vol. 60, no. 3, pp. 12061213, Mar. 2012. of Singapore (NUS), as an Assistant Professor in
[40] S. Gabriel, R. W. Lau, and C. Gabriel, The dielectric properties of bi- 2009 and was promoted to Associate Professor with tenure in 2013. He is also
ological tissues, Phys. Med. Biol. pp. 22312293, Oct. 2004. [Online]. Director of Center for Microwave and Radio Frequency at the Department
Available: http://niremf.ifac.cnr.it/tissprop/, (1996) of Electrical and Computer Engineering, NUS. Concurrently, he is a Senior
[41] CST Microwave Suite Ver. 2012.08 CST Voxel human body model, Investigator at the National University of Singapore Suzhou Research Institute
2013. [Online]. Available: http://www.cst.com (NUSRI), Suzhou, China, and Director of Center of Advanced Microelectronic
[42] IEEE Standard for Safety Levels With Respect to Human Exposure to Devices, NUSRI. He has authored or coauthored 137 international journal pa-
Radio Frequency Electromagnetic Fields, 3 kHz to 300 GHz, IEEE pers and 152 international conference papers. So far, his publications have been
Standard C95.1-1999, 1999. cited more than 1189 times and the H-index is 22 (source: Scopus). He holds
[43] IEEE Standard for Safety Levels With Respect to Human Exposure to one granted U.S. patent and four filed U.S. provisional patents. His current
Radiofrequency Electromagnetic Fields, 3 kHz to 300 GHz, IEEE Stan- research interests include microstrip antennas for wireless communications,
dard C95.1-2005, 2005. implantable/wearable antennas and body channel modeling for biomedical
[44] J. Jung, S. Zhu, P. Liu, Y. E. Chen, and D. Heo, 22-pJ/bit applications, wireless power and RF energy harvesting, microwave circuits,
energy-efficient 2.4-GHz implantable OOK transmitter for wire- and monolithic-microwave integrated-circuit modeling and design.
less biotelemetry systems: In vitro experiments using rat skin-mimic, Dr. Guo is the General Chair for 2015 IEEE MTT-S International Microwave
IEEE Trans. Microw. Theory Tech., vol. 58, no. 12, pp. 41024111, Workshop Series on Advanced Materials and Processes for RF and THz Appli-
Dec. 2010. cations (IMWS-AMP 2015), Suzhou, China. He was the General Chair for IEEE
[45] T. Karacolak, R. Cooper, J. Butler, S. Fisher, and E. Topsakal, In Vivo MTT-S International Microwave Workshop Series 2013 on RF and Wireless
verification of implantable antennas using rats as model animal, IEEE Technologies for biomedical and Healthcare Applications (IMWS-Bio 2013)
Antennas Wireless Propag Lett., vol. 9, pp. 334337, 2010. in Singapore. He served as a Technical Program Committee (TPC) Co-Chair
[46] F. Merli, B. Fuchs, J. R. Mosig, and A. K. Skrivervik, The effect for the IEEE International Symposium on Radio Frequency Integration Tech-
of insulating layers on the performance of implanted antennas, IEEE nology (RFIT2009). He has been a TPC member and session chair for numerous
Trans. Antennas Propag., vol. 59, no. 1, pp. 2131, Jan. 2011. conferences and workshops. He has also been on the editorial boards of the In-
ternational Journal of RF and Microwave Computer-Aided Engineering, and
International Journal of Microwave Science and Technology. He is serving as an
Associate Editor for IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS
(AWPL). He was a recipient of the Young Investigator Award in 2009, National
University of Singapore. He received the 2013 Raj Mittra Travel Grant Senior
Researcher Award.