CONTENTS

Page
No.
LIST OF ABBREBIATIONS, FIGURES AND TABLES i-vii

PREFACE 1-2

INTRODUCTION 3-5

REVIEW OF LIERATURE 6-24

GENERAL MATERIALS AND METHODS 25-33

CHAPTER I 34-52

Effects of environmental stressors (water and food deprivation,

pollutant) on the hypothalamic-pituitary-adrenal (HPA) axis of
laboratory mouse, Mus musculus
CHAPTER II 53-70

Evaluation of the effects of antineoplastic drug and herbicide on the

HPA axis
CHAPTER III 71-81

Effect of neuromodulator (Cannabis sativa leaf extract - Bhang) on the

HPA axis
CHAPTER IV 82-89

Evaluation of the xenobiotic effects of various stressors with special

reference to GST gene
SUMMARY AND CONCLUSION 90-98

REFERENCES 99-138

List of papers communicated/ accepted/ published/

presented
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