Nama : Windy Christine Sesa

Stambuk : N 101 12 020

Kelompok : II (Dua)
Angkatan : 2012
Tugas : 2 ( Journal Diagnostic)

WORKSHEET

Citation : The Validity of the Rapidly Diagnostic Tests for Early Detection
of Urinary Tract Infection

Are the results of diagnostic study valid?

Was there an independent, blind
comparison with a reference
(gold) standard of diagnosis?
Was the diagnostics test evaluated
in an appropriate spectrum of
patients (like those in whom it
would be used in practice)?
Was the reference standard applied
regardless of the diagnostic test
result?
Was the test( or cluster of tests)
validated in a second, independent
group of patients?

My Calculations

Micros. pyuria Totals

Present Absent
Dignostic Positive 41 8 49
test result (n=128) A b a+b
Negative 87 120 207
(n=128) C d c+d
Totals 128 128 256
a+c b+d a+b+c+d
Sensitivity = a/(a+c) = 41/(41+87)=41/128=32%

Specificity= d/(b+d) = 120/(8+120)=120/128=93,7%

LR+ = sensitivity/(1-specificity) = 32% / (1-93.7%)= 32%/6,3% = 5

LR- = 1-sensitivity)/specificity = (1-32%) / 93,7% = 68%/93,7% = 0,73

Positive predictive value (PPV) = a/(a+b) = 41/(41+8) = 41/49= 83,7%

Negative predictive value = d/(c+d)= 120/(87+120) = 120/207 = 58%

Pre test probability(prevalence)= (a+c)/(a+b+c+d) = (41+87)/

(41+8+87+120) = 128/256= 50%

Pre test odds = prevalence/(1-prevalence) = 50%/(1-50%)= 50%/50% = 1

Post test oods = (pre test odds) x LR = 1 x

Post test probability = (post test odds)/post test odds+1) =