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Why branded generics
matter in emerging markets
The genesis of branded generics in emerging markets is a pragmatic
response to some hard local market realities. Historically,
pharmaceutical companiesmuch as they do in developed
economieshave attempted to enforce intellectual property
(IP) rights in these regions as their economies became more
globally integrated. From the start, however, big pharma players
often had to compete against generic versions of their own
medications, which in many developed countries are protected
by law. The Indian market, for example, is inundated with
copycat generic drugs and low-cost chemically similar versions
due to historically weak patent laws and government-induced
pricing controls.3
These market conditions, coupled with The favorable margins of branded generics
lower consumer disposable income levels can provide room for a meaningful amount
and the inability of emerging market of promotional spending. Our research
governments to afford novel medications4 shows that emerging market healthcare
at developed country prices, helped to foster providers trust branded generic products the
a new, branded generics product segment. same way they rely on other novel medications
because they have been in use for a long
Just how well do branded generics measure timein some cases for decades. And given
up against branded and pure generic products the often-global reputations of the MNCs,
from a profitability perspective? The there is also an element of intrinsic trust
popularity of branded generics over pure in both the quality of branded generics and
generic products also varies by country with the companies that sell them.
branded ones enjoying a higher price leading
to more favorable margins when compared
to pure generics. In India, branded generics
and originator (off patent) brands dwarf
pure generic products, whereas in many
developed markets such as the United Kingdom
and United States, unbranded generics make
up about half the overall category total.
Branded generics typically offer higher
margins than either over-the-counter (OTC)
or pure generic offerings.
4 | Five Branded Generics Strategies to Master for Global Pharmaceuticals in Emerging Markets
5
Key success factors
with branded generics
in emerging markets
While the branded generics play in emerging markets offers
pharma players opportunities to expand, success is not certain.
To improve the odds, MNCs should consider the following five
winning elements of successful branded generics strategies.
Key Success
Factors with
Bolster the sales force Engage in portfolio
Branded Generics
with multi-channel marketing
engagement in Emerging Physician engagement and
Create trust and recognition Markets brand equity are critical for
among healthcare providers success
Recalibrate regulatory
affairs
Ability to file for the fastest route
for approval to outpace generics
Know how to navigate
government relationships
6 | Five Branded Generics Strategies to Master for Global Pharmaceuticals in Emerging Markets
1. emerging markets, pharmacies are owned
and operated by individuals and thus
offer a less predictable order horizon than
However, MNCs could be at a disadvantage
here, since theyunlike some local producers
can face stricter reporting standards
Establish sustained pharmacy chains. Even where there are
large pharmacy chains, such as in Latin
regarding their accounts payable terms.
7
Research and development Another recent development is the practice with establishing local R&D capabilities.
The announcement in December 2011 that of enrolling ever-larger patient populations Many other factors can play into this equation,
Merck planned to establish a new research from emerging markets for clinical trials. including nationalistic protectionism, which
and development (R&D) headquarters in Doing so can help to speed up patient promotes investments in local technologies
China as part of a $1.5 billion investment recruitment, which appears to have been by blocking the entry of MNCs and negative
over five years represents a milestone in an operational obstacle for clinical stage popular perceptions of government officials
MNC attempts to establish an integrated development. Due to lower treatment rates caused by their pricing, payment and
presence in the emerging market landscape. in emerging markets, the ability to find coverage decisions that focus on containing
As most MNCs move into China, this strategy more eligible patients has often attracted healthcare costs.
can be interpreted two ways. First, it allows drug developers (and the contract research
companies to gain access to an educated local organizations they use) to these geographies Local talent
workforce, enabling them to dial up discovery to perform Phase II and III clinical trials.
Since both MNCs and local branded generic
functions at a lower cost. And second, This practice can also help to speed up
manufacturers invest heavily in emerging
establishing the company as a net investor the approval process with emerging market
markets, the war for talent is a key success
in an emerging market can boost its influence regulatory authorities, because many sub-
factor. However, this pervasive demand for
with local governments, which almost always mission packages are mandated to include
talent can make the cost of hiring individuals
act as monopsony players (i.e., a single clinical outcomes data for local populations.
with the right skill sets disproportionately
buyer with multiple sellers) in countries However, MNCs should consider striving
expensive. In some cases, this trend has
that lack a healthy commercial insurance for full transparency in such trials which
actually reversed net immigration flows to
segment. The case of China in particular, can help to avoid the potentially negative
developed markets.
is a good example, where drugs developed perception that they are taking advantage
locally often enjoy a semi-official fast track of local populations, whose protections
Talent acquisition costs are also increasing
for reimbursement by local authorities that from negative outcomes may be lower than
steadily, bringing the fully-loaded cost of
may save them years in the process. those in developed markets. This issue is
a pharma sales rep in China, for example,
exemplified by claims made by an African
closer to developed country levels. In some
While pharmaceutical industry R&D has government concerning clinical trial
Eastern European countries and Russia, it
traditionally been a slow process, in India recruitment for an antibiotic tested by
is a common practice to hire physicians as
the adoption of reverse pharmacology has a large global pharma company, and led
sales reps, because doctors can often earn
provided production efficiency gains, helped to a major public relations issue that was
multiples of their government-paid salaries.
manufacturers to test generic drugs more drawn out over many years.
quickly and thus helped to increase the Continuing education, training and sustainable
speed to market. The ability to bring relevant Becoming involved locally can actually
career paths in a MNC remain important
products quickly to market at low price enhance a big pharma players image in
attributes in the war for local talent. However,
points has been instrumental for domestic the eyes of local healthcare providers,
MNCs may be slowly losing this edge to
players in shaping the Indian market on positioning it as a progressive and innovative
local branded generic manufacturers, which
their terms. company that supplies high quality products.
historically have attempted to lure talent
However, companies should consider
away from big pharma companies once people
weighing the costs and benefits associated
complete their initial training and gain
hands-on multi-national commercialization
experience. Now, the local players offer
similar perks and career paths as well.
In general, rates of attrition seem to be
Partner with local players uncharacteristically high in emerging markets,
Successful MNCs often create partnerships with local companies with deeper since companies do not shy away from
expertise in the local market and perhaps more support from the local stealing trained talent from anyone, anywhere.
government. Bayer HealthCare, for example, recently launched a joint venture
with Cadila, one of Indias largest privately held pharmaceutical companies.
These ventures are also often designed to establish a new base for expansion
into other emerging markets. In 2009, GSK signed an agreement with Indias
Dr. Reddys to develop and market selected products across a variety of
emerging markets.8
8 | Five Branded Generics Strategies to Master for Global Pharmaceuticals in Emerging Markets
2. The ability to create strong brand equity
by engaging in portfolio marketing is a key
factor for success with branded generics in
Leveraging a portfolio of products can allow
companies to benefit from synergies as they
execute their strategy and develop a market
Engage in portfolio emerging markets. The strength of the sales
and marketing organization and its capabilities
presence. Engaging in portfolio marketing
can generate efficiencies by enabling field
marketing in terms of field sales, promotions, market
research and medical services can play a
sales teams to promote multiple products
with physicians, further improving their
critical role in creating such brand equity. ability to succeed in this competitive market
with a branded generic. The MNCs know-
Physician engagement and the creation of how regarding the specific therapies and
brand equity can be even more important the market can further improve their speed
for the success of the branded generic when to market, thus building their local brand
the original drug has been off-patent for equity. Novartis business in India is a perfect
some time and other generics have already example of this approach, as most of the
been launched in the market. investment has been focused on creating
awareness of diseases among local populations
Companies with a branded generics portfolio in rural settings under an umbrella brand,
tend to have divisions focused on certain Arogya Parivar, which means good family
therapies. This can foster the opportunity health in Hindi.
for them to increase their depth in a specific
therapy by conducting focused market Promotional activities can help MNCs
research and to develop a good understanding maintain the relevance of branded generic
of a markets medical needs, which in turn offerings in a market, and doing upfront
can help them to gain recognition among portfolio lifecycle planning and taking steps
physicians. For example, Sandoz remains to understand target segment needs can
the leader in tuberculosis therapy in India place the MNC in a strong commercial
because it has the most relevant portfolio, position with its branded generic offerings.
which it markets as a comprehensive package.
9
3. The regulatory affairs department of a
MNC typically plays a different role when
dealing with branded generics in emerging
In many markets, established relationships
are an important element of regulatory
affairs performance and it is not unusual
Recalibrate markets than it does generally in developed
countries. In fully industrialized economies
for former government officials and/or
regulators to join the ranks of local or
regulatory affairs the regulatory affairs function primarily
focuses on providing guidance about a new
multi-national companiesa practice
common in India. MNCs are often required
products labeling and seeks to optimize the to navigate these cultural norms and
ability to promote products on a post-approval manage the risks to which they may be
basis while ensuring full compliance. In exposed concerning their governing compliance
emerging markets, on the other hand, the policies, while at the same time being clear
ability to accelerate the companys go-to- when it comes to intent and desired outcomes.
market capability by moving the branded
generic application dossier through multiple Overall, MNCs that play in the branded
bureaucratic hurdles is a key capability that generic space often benefit from a versatile
regulatory affairs personnel must master. regulatory affairs function that can enable
Turkey, for example, can be a difficult market smooth and agile go-to-market performance.
for pharma players due to its challenging
regulatory environment, which causes a
significant backlog in the registration process
typically from 18 to 36 months.10 Likewise,
the strong influence of the Chinese
government and the uncertainty around
future healthcare regulatory reforms make
China a complex market for MNCs.
Give back
Non-profit engagements can offer a way for pharmaceutical players to build
brand strength in emerging markets that is consistent with their corporate
philosophy of improving healthcare. Contributing to the local economy or
infrastructure can help build goodwill and winning over a customer base that
recognizes a companys brand. It also can become a vehicle to elevate the
corporate image to attract and retain local talent who feel particularly proud
about working for the company.
10 | Five Branded Generics Strategies to Master for Global Pharmaceuticals in Emerging Markets
4. In-person, face-to-face interactions remain
a core strategy for marketing products to
providers in emerging markets. Many MNCs
A multi-channel marketing strategy leveraging
newly adopted channels (such as digital
access) has the potential to reach a broader
Bolster the are investing in sales reps, who play a vital
role in product education and relationship
audience to deliver core branded generics
messaging. One key goal of this strategy
sales force with building. However, as emerging markets
grow and an increasing number of individuals
is instilling trust and recognition among
health care providers and consumers for
11
5. In many emerging markets, the contracting
or tendering process is an area of focus for
MNCs. As a result, cultivating effective
deal with the potential inconsistencies that
can arise when customers have low levels
of influence over the prices they pay. One
Enhance contracting contracting capabilities is a strategy that
can help MNCs win the branded generics
often-valuable discounting strategy involves
offering incentives for purchases across
capabilities game. Currently, the emerging market
tendering process is typically low-tech
an MNCs portfolio of products, which can
help companies sell both patented and off-
and reactive rather than proactive. In patent drugs and MNCs can incorporate as
many markets, the individuals in charge appropriate in the local market. MNCs can
of contracting and tendering processes gain market share and potentially create
simply use Microsoft Excel spreadsheets positive prescribing spillover for off-patent
to track historical bid prices, and decision- drugs, which is often difficult to execute in
makers lack ready access to data or the a low transparency market.
tools they need to drive actionable insights.
Tenders, typically the main source of high-
In order to compete with local players in India volume sales opportunities-often gain even
such as Ranbaxy and Dr. Reddys, MNCs more importance in the overall commercial
could benefit from viewing contracting and plan. As a consequence, identifying tenders
tendering as a commodities game involving by investing in third-party aggregating
a robust and dynamic pricing capability, rather services or by establishing data-sharing
than one focused on brands. Additionally, relationships with distributors may be
the tendering process for off-patent essential to finding profitable opportunities
products includes the additional complexity in this product segment. MNCs are largely
of dealing with generic competitors whose dropping out of this game (e.g., in Brazil)
price points are generally unknown. Preparing and where they continue to play (e.g.,
multiple bidding scenarios can help MNCs China), the pressure is intensifying.
12 | Five Branded Generics Strategies to Master for Global Pharmaceuticals in Emerging Markets
13
Conclusion
Branded generics in emerging markets present a viable avenue
for potential growth for big pharma players, but companies need
to understand the often-unique challenges they face in pursuing
this opportunity. With the increasing pressure on government
budgets and cost containment, the window of opportunity that
the branded generics present may not stay open for long. Therefore,
MNCs should consider exploring and pursuing a select combination
of the strategies discussed in this publication with a sense
of urgency.
Five Branded Generics Strategies to Master for Global Pharmaceuticals in Emerging Markets
End notes
1 Credit Suisse Global Investment Returns 9 Novo Nordisk to Reach 2500 Children in
Yearbook 2010, Elroy Dimson, Paul Marsh, India with Free Insulin and Diabetes Care,
Mike Staunton, Jonathan Wilmot. Novo Nordisk Press Release, September 7,
2 IMS Health, The Global Use of Medicines: 2011.
Outlook Through 2016, July 2012, Page 3. 10 Country Report; Turkey, Steve
3 India: Good Endings, Good Beginnings, Kretschmer, Pharmaceutical Market Europe,
Pharmaceutical Executive, September 2011. May 2011.
4 Drugs that offer benefits that are 11 Digital Channels Reaching Doctors in
differentiated from those offered by other China, Anne ORiordan, Kher Tean Chen,
products in the market. Accenture, December 21, 2011.
15
About the authors Contact us About Accenture
Kristina Gilbert is a senior executive in Kher Tean Chen () is a senior Accenture is a global management consulting,
Accentures Management Consulting executive in Shanghai, China. technology services and outsourcing company,
practice. Kristina brings over 14 years kher.tean.chen@accenture.com with 257,000 people serving clients in
of experience consulting with global Life more than 120 countries. Combining
Sciences clients on strategy, new commercial Marcelo Duerto is a senior manager based unparalleled experience, comprehensive
models and emerging markets growth in Buenos Aires, Argentina. capabilities across all industries and business
opportunities, including building commercial marcelo.v.duerto@accenture.com functions, and extensive research on the
capabilities for new markets, customers, worlds most successful companies, Accenture
and go-to-market approaches. She is based Sriram Shrinivasan is a senior executive in collaborates with clients to help them
in Philadelphia, Pennsylvania. Mumbai, India. become high-performance businesses and
kristina.l.gilbert@accenture.com governments. The company generated net
sriram.shrinivasan@accenture.com revenues of US$27.9 billion for the fiscal
year ended Aug. 31, 2012. Its home page is
Arda Ural is a senior manager in Accentures www.accenture.com.
Life Sciences Strategy practice. Prior to The authors would like to thank
joining the firm, he was a VP Strategic Olivier Jarry3xBL Consulting
Marketing at Becton Dickinson (BD) and for contributing to this article. Life Sciences Practice
served as the SVP Marketing & Sales for a Accentures Life Sciences practice is
start-up biotechnology company Eyetech dedicated to helping companies rethink,
(later acquired). He started his career at reshape or restructure their businesses
Pfizer In Turkey and over 10 years had to deliver better patient outcomes and
global and US commercial responsibilities. drive shareholder returns. We provide
Arda is based in New Jersey. consulting, outsourcing and technology
arda.ural@accenture.com around the globe in all strategic and
functional areaswith a strong focus
on R&D, Sales & Marketing and the Supply
Myriam E. Lopez is a senior manager
Chain. We have a long history of working
in Accentures Management Consulting
hand in hand with our clients to improve
practice. She brings over 12 years of
their performance across the entire Life
Life Sciences experience in industry and
Sciences value chain. Accentures Life
consulting. Myriam has focused on helping
Sciences practice connects more than
organizations with the creation of their
10,000 skilled professionals people in over
growth strategy, market expansion approach,
50 countries who are personally committed
emerging markets penetration plan, and
to helping our clients achieve their business
capabilities development roadmap. She has
objectives and deliver better patient
led the global launch of several medical device
outcomes for people around the world.
products. Myriam is based in New Jersey.
myriam.e.lopez@accenture.com