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Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing

Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Interferes with Hypersensitivity to Hypersensitivity Administer prescribed
Levofloxacin Fluoroquinolone antibiotic Tablets 250 - 500 microbial DNA fluoroquinolones, reactions, sometimes dose with a full glass of
mg synthesis. quinolone antibiotics, fatal, including water.
or any product anaphylactic/anaphylact
Brand Name: Indication: component. oid reactions, Administer without
Route: anaphylactic shock, regard to meals, but
Levaquin Oral/IV angioneurotic edema, administer with food if
and serum sickness GI upset occurs.
(postmarketing).
Frequency: Administer levofloxacin
Every 24 h for 7 2 h before or after
days magnesium or
aluminum antacids,
sucralfate, iron
supplement,
multivitamin with
minerals, or didanosine
chewable/buffered
tablets or oral solution.
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Inhibits protein Contraindicated with CV: Hypotension, Take oral drug with a
Clindamycin Lincosamide antibiotic 300 mg/ 1 cap synthesis in allergy to clindamycin, cardiac arrest (with full glass of water or
Pregnancy Category B Route: susceptible bacteria, history of asthma or rapid IV infusion) with food.
Oral causing cell death. other allergies,
Brand Name: tartrazine (in 75- and GI: Severe colitis, Take full prescribed
Cleocin Frequency: 150-mg capsules); including course of oral drug.
Indication: q6h hepatic or renal pseudomembranous Do not stop taking
Systemic administration: dysfunction; lactation. colitis, nausea, without notifying health
Serious infections caused by vomiting, diarrhea, care provider.
susceptible strains of abdominal pain,
anaerobes, streptococci, esophagitis, anorexia, You may experience
staphylococci, pneumococci jaundice, liver function these side effects:
Parenteral: Treatment of changes Nausea, vomiting (eat
septicemia caused by frequent small meals);
staphylococci, streptococci; Hematologic: superinfections in the
acute hematogenous osteom Neutropenia, mouth, vagina (use
yelitis. leukopenia, frequent hygiene
agranulocytosis, measures; request
eosinophilia treatment if severe).

Hypersensitivity: Report severe or watery


Rashes, urticaria to diarrhea, abdominal
anaphylactoid reactions pain, inflamed mouth or
Local: Pain following vagina, skin rash or
injection, induration and lesions.
sterile abscess after IM
injection,
thrombophlebitis after
IV use
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Possible increased Contraindicated with CNS: Dizziness, light- Take with meals if upset
Amlodipine besylate Calcium channel-blocker 10 mg/ 1 tab serum levels and allergy to amlodipine, headedness, stomach occurs.
Antianginal drug toxicity of impaired hepatic or headache, asthenia, fatig
Antihypertensive cyclosporine if taken renal function, sick ue, lethargy You may experience
Brand Name: Pregnancy Category C Route: concurrently sinus syndrome, heart these side effects:
Norvasc Oral block (second or third CV: Peripheral Nausea, vomiting (eat
degree), lactation. edema, arrhythmias frequent small meals);
Indication: headache (adjust
Angina pectoris due to Frequency: Use cautiously with Dermatologic: Flushing lighting, noise, and
coronary artery spasm OD CHF, pregnancy. , rash temperature; medication
(Prinzmetals variant angina) may be ordered).
GI: Nausea, abdominal
Chronic stable angina, alone discomfort Report irregular
or in combination with other heartbeat, shortness of
agents breath, swelling of the
hands or feet,
Essential hypertension, pronounced dizziness,
alone or in combination with constipation.
other antihypertensives
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Competitively blocks Increased effectiveness CNS: Dizziness, Take drug with meals.
Carvedilol Alpha- and beta-adrenergic 25 mg, 1 tab alpha-, beta-, and of antidiabetics; vertigo, tinnitus,
blocker beta2-adrenergic monitor blood glucose fatigue, emotional Do not stop taking drug
Antihypertensive receptors and has some and adjust dosages depression, paresthesias, unless instructed to do
Brand Name: Pregnancy Category C Route: sympathomimetic appropriately. sleep disturbances so by a health care
Coreg Oral activity at beta2- provider.
receptors. Both alpha Increased effectiveness CV: Bradycardia,
Indication: and beta blocking of clonidine; monitor orthostatic Avoid use of OTC
Hypertension, alone or with Frequency: actions contribute to patient for potential hypertension, CHF, medications.
other oral drugs, especially OD the BP-lowering severe bradycardia and cardiac arrhythmias,
diuretics effect; beta blockade hypotension pulmonary edema, You may experience
prevents the reflex hypotension these side effects:
Treatment of mild to severe tachycardia seen with Depression, dizziness,
CHF of ischemic or most alpha-blocking GI: Gastric pain, light-headedness (avoid
cardiomyopathic origin with drugs and decreases flatulence, constipation, driving or performing
digitalis,diuretics, ACE plasma renin activity. diarrhea, hepatic dangerous activities;
inhibitors Significantly reduces failure getting up and changing
plasma renin activity. positions slowly may
Left ventricular dysfunction Respiratory: Rhinitis, p help ease dizziness).
(LVD) after MI haryngitis, dyspnea

Unlabeled uses: Angina (25 Other: Fatigue, back


50 mg bid) pain, infections
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Decreases fever by Hypersensitivity Low fever with nausea, Assess patients fever or
Paracetamol Analgesic, Antipyretics 325 - 650 mg inhibiting the effects stomach pain, and loss pain: type of pain,
(Acetaminophen) of pyrogens on the intolerance to of appetite; location, intensity,
hypothalamus heat tartrazine (yellow dye Dark urine, clay-colored duration, temperature,
Indication: Route: regulating centers & #5), alcohol, table stools; or and diaphoresis.
Brand Name: Relief of mild-to-moderate Oral/IV by a hypothalamic sugar, saccharin Jaundice (yellowing of
Biogesic pain; treatment of fever. action leading to the skin or eyes) Assess allergic
sweating & Contraindicated with reactions: rash,
Frequency: vasodilatation. allergy to urticaria; if these occur,
Q4 or PRN acetaminophen drug may have to be
Relieves pain by discontinued.
inhibiting
prostaglandin Teach patient to
synthesis at the CNS recognize signs of
but does not have anti- chronic overdose:
inflammatory action bleeding, bruising,
because of its minimal malaise, fever, sore
effect on peripheral throat.
prostaglandin
synthesis. Tell patient to notify
prescriber for pain/
fever lasting for more
than 3 days
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Gastric-acid pump Hypersensitivity to CNS: headache, History:
Omeprazole Antacids, Anti reflux Agents 40 mg inhibitor: suppresses omeprazole or its dizziness, hypersensitivity to
& Anti Ulcerants Anti- gastric acid components. Use asthenia,vertigo,insomni omeprazole or any of its
secretory drug Route: secretion by specific cautiously with a,apathy,anxiety, paresth components; pregnancy,
Brand Name: Oral/IV inhibition of the pregnancy, lactation esias,dreamabnormalitie lactation
Prilosec hydrogen-potassium s Physical: skin lesions;
Indication: ATPase enzyme reflexes; urinary output;
Short-term treatment Frequency: system at the secretory Dermatologic: rash, abdominal examination;
of active duodenal OD surface of the gastric inflammation, respiratory auscultation
cancer Short-term treatment parietal urticaria pruritus Interventions:
of active benign gastric ,alopecia, dry skin 1. Administer before
ulcer Eradication meals.
of Helicobacter Pylori First- GI: diarrhea, 2. Administer antacids
line therapy for treatment abdominal pain, nausea, with, if needed.
of heartburn or symptoms vomiting, constipation, Have regular medical
of GERD dry mouth, tongue follow-up visits.
atrophy Report severe headache,
worsening of
Respiratory: URI symptoms, fever, chills
symptoms, cough
epistaxis
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Selective inhibition of -Lactating Mother - Nausea and Vomiting Check for doctors
Trimetazidine Anti-angina 35 mg/ 1 tab an enzyme of fatty -Pregnancy -Headache order
acid -oxidation: the -Edema Monitor blood pressure
Route: long-chain 3-ketoacyl and pulse rate before
Brand Name: Indication: Oral/IV CoA thiolase (3-KAT). and after giving the
Vastarel Acute angina attacks- This inhibition results meds.
prevent situation that may in: Reduction in fatty Notify prescribing signs
cause anginal attacks Frequency: acid oxidation; of heart failure such as
BID Stimulation of glucose swelling of hands and
oxidation. The feet or SOB.
coupling of glycolysis Advise patient of the
with glucose oxidation side effects of the drug
is improved and ATP
production
is further increased,
while cell acidosis and
Ca2+ overload are
limited. The increase
in total glucose
utilization has been
evidenced by studies
using 18FDG positron
emission tomography
(PET).
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Lowers glucose level -Hypoglycemia Drug has a more rapid
Insulin Glulisine Insulin 5 units by increasing -Hypokalemia onset and shorter
peripheral glucose -Injection site reaction duration of action than
Route: uptake and decreasing -Lipodystrophy regular human insulin.
Indication: Subcutaneous hepatic glucose -Pruritus Give within 15 minutes
Brand Name: Diabetes mellitus in adults. production. -Rash before or immediately
Apidra Usually used in regimens after a meal.
that include a longer-acting Frequency:
insulin or basal insulin Before meals When used in an
analog. external subcutaneous
infusion pump, dont
mix drug with any other
insulin or diluent.
Drug Classification/ Dose, Route, Mechanism of Action Contraindication Side Effects Nursing
Indication Frequency Responsibilities

Generic Name: Classification: Dosage: Lower blood glucose Hypoglycemia, -Hypoglycemia Instruct patient and
Insulin glargine Anti-diabetics, hormones 19 units by stimulating glucose allergy or -Hypokalemia family on
uptake in skeletal hypersensitivity. Use -Injection site reaction administration
Route: muscle and fat, cautiously during -Lipodystrophy technique.
Brand Name: Indication: Subcutaneous inhibiting hepatic stress and infection. -Pruritus Explain that this
Lantus Indicated in treatment of glucose production. -Rash controls hyperglycemia,
diabetes mellitus. but does not cure
Frequency: diabetes.
Before meals Instruct patient in
proper testing of blood
sugar and ketones.
Emphasized the
importance of diet and
regular exercise.
Instruct patient on signs
and symptoms of
hypoglycemia.
Diabetics should carry a
source of sugar incase
this happens.