Академический Документы
Профессиональный Документы
Культура Документы
Kajjali is also one of the prime ingredients in dark in color. And at this moment, the juice
various Rasayoga (herbo-mineral was said to be saturated with impurities
formulations) and is used as a medicine from the impure Mercury. The juice was
separately.[6] taken out of the Khalva and the surface of the
The process of constant trituration of Mercury was washed with water and cleaned
Parada (mercury) and Gandhaka (sulphur) with cotton.
will eventually pack the Sulphur molecules in Fresh garlic juice was then added and
between the layers of Mercury molecules.[7] the trituration process continued. Ayurvedic
As the trituration continues, the compact texts stipulate that this step should be
placement of Sulphur becomes more fixed. repeated at least 7 times. In other words,
Thus, owing to this compact there should be at least 7 trituration cycles
structure, after oral administration of with fresh garlic juice.
Kajjalikalpa, the sustained release of active After that, Mercury is eventually
molecules takes place. Hence, also in clinical washed with warm water till a clear, mirror
practice, it is observed that timed release like surface is obtained. Then only, the
and sustained release theories of drugs Mercury could be assumed to be purified.
triturated with Kajjali are more than the The actual purification process of the
drugs administered without Kajjali. Mercury used for the study was done over a
MATERIALS AND METHODS period of 3 days comprising of 8 hours of
trituration daily.
Ingredients:
It is important to note that only
1. Shuddha Parada (Purified Mercury) purified Mercury can be employed in
2. Shuddha Gandhaka (Purified Sulphur) Ayurvedic treatment, as per the texts;
The ingredients were procured from because impure Mercury can be the cause of
Punarvasu Aushadhshala Pvt Ltd. Shiv Kamal various imbalances and hence lead to the
industrial estate, Shivanegaon, Pune, India advent of toxicity. (Fig. 1)
and all the materials were thoroughly Purification of Gandhaka (Sulphur)[9]
screened by rasashastra experts based on A wide mouth Ghata (earthen vessel)
the GrahyaLakshanas (characteristics) was taken and filled with Goghrita (Cows
mentioned in the classics. ghee), then the mouth of the vessel was
The study was conducted at Sinhgad covered by a cloth and tied by iron wire.
College of Pharmacy, Vadgaon (Bk), Pune Coarse powder of Gandhaka was spread
41. However, the SEM and the determination upon the cloth and closed with another
of the % of Mercury and Sulphur by AAS earthen vessel by placing upside down.
(Atomic Absorption Spectroscopy) were The edges of both the vessels were
carried out at Diya Labs, Mumbai. sealed with Multanimitti (Fullers earth). The
Purification of the Ingredients cloth was then smeared for ten minutes and
Purification of Parada (Mercury)[8] allowed to dry under sunlight. This Yantra
(apparatus) was kept inside a pit (1.5 feet)
The purification of Parada (Mercury) beneath the surface of the soil in such a way
was achieved using garlic juice. The impure that the brim of the vessel was at ground
Mercury, procured from the market by level. Empty spaces of the pit around the
Punarvasu Aushadhshalam Pvt Ltd, was apparatus were filled with soil. Cow dung
taken in a clean and dry khalva and fresh cakes were kept on the brim of the vessel
garlic juice was added. Quantity of which and set on fire.
should be sufficient to cover the entire
mercury surface. The Sulphur, after melting by fire,
flows down through the cloth into the vessel,
The Mercury was triturated in a slow which contained milk and ghee. After
and steady fashion till the garlic juice turned Svangasita (self cooling), the apparatus is
Available online at : http://ijapr.in Page 51
Int. J. Ayur. Pharma Research, 2014; 2(5): 50-57 ISSN: 2322 - 0910
taken out of the pit and Sandhibandhana rubbed for a specific time period (24 30
(seal) was opened carefully. Purified hours) till a fine black powder was obtained.
Gandhaka (in granule form) was collected This was done over a period of three days
from the bottom of the vessel and washed comprising of eight hours of rubbing
with hot water. (Fig. 2) continuously for each day.
Preparation of The Kajjali The process was stopped after three
Four types of Kajjali can be prepared days as the Kajjali was confirmed to have
in a ratio of weight of Mercury to weight of been formed. (Fig. 3 and Fig. 4)
Sulphur and these types are categorized into 2nd method: Modern (Grinding) Method
four different groups as per the ancient 500 g of purified Sulphur was taken in
Ayurvedic texts. They are as follows:- a Khalva and rubbed for 15 minutes and then
Group 1= 1:1 500g of purified Mercury was added and
Group 2= 1:2 rubbed for 45minutes till a coarse faint black
powder was obtained and the mixture was
Group 3= 1:3 ground in a mixer grinder for 30-60 seconds.
Group 4= 1:6 This procedure was repeated with an
Group 1: Samagunabalijarita Kajjali was interval of 10-15minutes till a black powder
taken for study. was obtained and rubbed for 12 hours in a
Khalva. (Fig. 5)
This group of Kajjali was choosen as it is the
most frequently used in Ayurvedic Note: For both the methods, the completion
treatment. of the process was confirmed when there
was no sign of Chandrika (shiny particles of
Within this group two methods of Kajjali Mercury) in the black powder obtained. This
preparation were tried. was checked by assessing the presence of
1st method: Traditional method shiny particles, if any, under sunlight.
(Rubbing) The general procedure and the timing have
350g of purified Mercury and 350 g of been tabulated below.
purified sulphur were taken in a Khalva and
PHOTOGRAPHS
Fig 9. Kajjali being prepared in grinder Fig 10. Kajjali being prepared in grinder