ARTICLE ABOUT HEALTH

1 Causes of baldness, gray hair identified

A study of a rare genetic disease may have yielded a cure for hair graying
and baldness, after researchers unintentionally discovered the mechanisms
that give rise to the conditions.

Researchers have pinpointed the mechanisms that promote gray hair

and baldness.

Study co-author Dr. Lu Le, of the Harold C. Simmons Comprehensive Cancer

Center at the University of Texas Southwestern in Dallas, and colleagues set
out to investigate a disorder called neurofibromatosis type 1 (NF1), a genetic
condition whereby tumors grow on nerves.

The aim of the study was to discover the mechanisms behind tumor growth
in NF1. Instead, the researchers identified the processes responsible for hair
loss and graying, a discovery that could lead to new treatments for the
conditions.

The researchers recently reported their findings in the journal Genes and
Development.

According to the American Hair Loss Association, by the age of 35, around
two thirds of men in the United States will experience some degree of hair
loss, and of all those with the condition in the U.S., 40 percent are women.

When it comes to hair graying, a 2012 study found that around 6 to 23

percent of adults across the globe can expect to have at least 50 percent
gray hair coverage at the age of 50 years.

While hair loss and graying are considered by many as a normal part of
aging, for some, the conditions can be highly distressing. Dr. Le and
colleagues believe that their discovery could pave the way to new
treatments for hair graying and baldness.

Findings may lead to topical treatments

The team notes that studies had already determined that hair follicles
contain stem cells that play a role in hair production, and that a protein
called stem cell factor (SCF) is involved in hair pigmentation.
In their study, Dr. Le and team found that once stem cells move to the base
of hair follicles, a protein called KROX20 - better known for its role in nerve
development - is activated in skin cells that form hair shafts, known as hair
progenitor cells.

The researchers found that when KROX20 is activated, the hair progenitor
cells produce SCF, which they discovered is crucial for hair pigmentation.

In mice with skin cells that possessed both KROX20 and SCF, the researchers
found that the skin cells communicated with melanocyte cells to form
pigmented hairs. Melanocyte cells produce melanin, the pigment that gives
color to the skin, hair, and eyes.

When the researchers deleted SCF in the mice, the researchers

found that the rodents grew gray hairs, and these hairs turned
white with age. When KROX20-producing cells were erased, the
mice did not grow any hair.

The researchers say that their findings indicate that abnormalities in KROX20
and SCF play a significant role in hair loss and graying, though studies in
humans are required to confirm their results.

Still, Dr. Le and colleagues believe that their findings show promise for the
development of new therapies for baldness and hair graying.

2. People who sleep longer twice as likely to

develop dementia
Alzheimer's disease affects millions of Americans, and the numbers are
expected to grow. New research suggests there may be a link between
prolonged sleep and the risk of dementia.

New research suggests those who sleep for more than 9 hours each

night are at a higher risk of developing dementia.

Over 46 million people are living with dementia worldwide, and the number
is expected to almost triple by 2050.
In the United States, over 5 million people are currently estimated to have
Alzheimer's disease. The disease risk increases with age, as 1 in 3 seniors die
with Alzheimer's or another form of dementia.

The financial burden of the disease is also great. American families are
believed to spend over $5,000 yearly on caring for someone with
Alzheimer's, and the national economic burden is estimated at $236 billion.

A new, large-scale study suggests people with prolonged sleeping patterns

may have an increased risk of developing dementia.

The research was led by Dr. Sudha Seshadri, professor of neurology at

Boston University School of Medicine (BUSM), and the findings were
published in the journal Neurology.

Researchers examined data from the Framingham Heart Study (FHS). FHS is
a large cohort study that started in 1948 by enrolling 5,209 men and women
aged between 30 and 62 living in the town of Framingham, MA. The original
purpose of the study was to identify risk factors for cardiovascular disease.

Sleeping 9 hours or more linked to greater dementia risk

For this study, a large number of adults enrolled in the FHS were asked to
report how long they usually slept per night. The researchers then clinically
followed the participants for 10 years to see who developed Alzheimer's
disease and other forms of dementia.

BUSM researchers then examined the data collected on sleep duration and
calculated the risk of developing dementia.

The team found that people who sleep regularly for 9 hours or more
were twice as likely to develop Alzheimer's within 10 years,
compared with those who consistently slept less than 9 hours.

Additionally, as the study's lead author explains, education seems to be

playing a role in staving off the risk of dementia.

"Participants without a high school degree who sleep for more than 9 hours
each night had six times the risk of developing dementia in 10 years as
compared [with] participants who slept for less. These results suggest that
being highly educated may protect against dementia in the presence of long
sleep duration."

Dr. Sudha Seshadri

The study also found that people who slept longer seemed to have smaller
brain volumes. Being observational, the study cannot establish causality, but
the researchers suspect excessive sleep is probably a symptom rather than a
cause of the neuronal changes that come with dementia. As a consequence,
they speculate, reducing sleep duration is not likely to lower the risk of
dementia.

The authors believe the findings may inform future dementia and cognitive
impairment detection practices. Co-corresponding author Matthew Pase,
Ph.D., who is a fellow in the department of neurology at BUSM and
investigator at the FHS, weighs in on the significance of the findings.

"Self-reported sleep duration may be a useful clinical tool to help predict

persons at risk of progressing to clinical dementia within 10 years," he says.
"Persons reporting long sleep time may warrant assessment and monitoring
for problems with thinking and memory."

The sooner a patient is diagnosed with dementia, the more time they and
their families have to plan ahead and make crucial healthcare decisions.

3. Red meat: Good or bad for health?

Red meat contains numerous vitamins and minerals that are essential for a
healthful, balanced diet. In recent years, however, its reputation has been
severely blemished, with studies suggesting that red meat intake can
increase the risk of cancer and other diseases. But is it really that bad for us?
We investigate.

Intake of red meat in the U.S. has fallen dramatically over the past 4
decades.

Red meat is defined as any meat that comes from mammalian muscle. This
includes beef, lamb, pork, goat, veal, and mutton.

For many households, red meat is considered a food staple, with some of us
consuming beef, lamb, and pork in different variations on a daily basis.

Last year, the average person in the United States is estimated to have
consumed around 106.6 pounds of red meat. Although this might appear a
high intake, it is a significant reduction from the average 145.8 pounds
consumed per capita in 1970.
Over the past 10 years alone, red meat consumption has fallen by around 10
pounds per person, with 2014 seeing the lowest intake of red meat since
1960, at just 101.7 pounds per person.

But why are so many of us cutting down on red meat?

A shift toward plant-based foods

According to a 2016 Harris Poll, approximately 8 million adults in the U.S. are
vegetarian or vegan, with concerns about animal welfare being the driving
factor.

However, it seems that millions more of us are opting for plant-based foods
over meat-based products because we believe that they are more healthful.
The 2016 Harris Poll found that 37 percent of U.S. adults "always" or
"sometimes" eat vegetarian meals when eating out, with 36 percent of these
citing health reasons for their choice.

A number of studies have suggested that when it comes to health, a plant-

based diet is the way to go. In December 2016, a position paper from the
Academy of Nutrition and Dietetics claimed that a plant-based diet can lower
the risk of type 2 diabetes by 62 percent, as well as reduce the risk of heart
attack and stroke.

"If you could

4. Vitamin C can target and kill cancer stem cells,

study shows
Cancer is currently one of the top killers worldwide, and the number of
cancer cases is only expected to rise. Although there are a number of
therapies available, most of them are toxic and cause serious side effects.
New research examines the impact of the natural vitamin C on cancer cell
growth.

In a recent study, vitamin C proves effective in killing cancer stem-like

cells.

Cancer is the second leading cause of death and disease worldwide,

accounting for almost 9 million deaths in 2015, according to the World Health
Organization (WHO).
The global number of new cases of cancer are expected to grow by around
70 percent in the next 20 years.

In the United States, the National Cancer Institute (NCI) estimate that almost
40 percent of U.S. men and women will have developed cancer at one point
during their lives.

There are various treatment options available for cancer, but they are not
always effective; most of them are toxic, and they tend to have a variety of
side effects.

In some more aggressive cases, the cancer does not respond to treatment,
and it is believed that cancer stem-like cells are the reason why the cancer
comes back and metastasizes.

New research, published in the journal Oncotarget, examines the

effectiveness of three natural substances, three experimental drugs, and one
clinical drug in stopping the growth of these cancer stem cells (CSCs.)

The study was conducted by researchers from the University of Salford in

Manchester in the United Kingdom, and was led by Dr. Gloria Bonuccelli.

Vitamin C up to 10 times more effective than experimental drugs

In total, the researchers measured the impact of seven substances: the

clinical drug stiripentol, three experimental drugs (actinonin, FK866, and 2-
DG), and three natural substances (caffeic acid phenyl ester (CAPE), silibinin,
and ascorbic acid (vitamin C).)

The research focused on the bioenergetic processes of CSCs, which enable

the cells to live and multiply. The study aimed to disrupt the CSCs'
metabolism and ultimately prevent their growth.

Of all the substances tested, the team found that actinonin and
FK866 were the most effective. However, the natural products were
also found to prevent the formation of CSCs, and vitamin C was 10
times more effective than the experimental drug 2-DG.

Conclusion Article about health make us know what the advantage

and disadvantage. Healthy is the most important in our life.

ARTICLE ABOUT TRAVELLING

1. 5 Tips In Finding Hotel
You are planning a holiday abroad for your family, and want
everyone to have a good time. You surf the internet for hotel
descriptions, but from the pictures you see and what you read, all
hotels project a perfect image of themselves. How can you know
which one is better? You have never been there and knows nothing
of your destination. At the same time, you do not want a hotel room
to spend your budget. How do you choose?

Check Independent Hotel Rating

Well, the first step you can take is to visit the hotel to see the
search engine ratings from previous visitors. In order assessments
for every hotel, most agents ask for an assessment of previous
guests. Reading their comments will give you a fair idea of what to
expect from the hotel which is located in your destination. Make
sure to read some of the comments in order to get a fair picture.
Certain incidents described only a rare occurrence that may have
been corrected.

Hotel Chains and Facilities

Are they part of an international hotel chain? Most international

chains have strict standards attached and the default theme in all of
the chain. They may have the same amenities (health club, spa,
business center, etc.) are essential to maintain a high standard of
hotel. Other things you can look out for shuttle services including
concierge, to the city, airport transfers and laundry service is good.

Location

Perhaps one of the most important things when choosing a hotel is

the location. Hotels close to shopping center, train station or city
center level higher charge than those located elsewhere. Analyzing
maps of the area before you order to determine the nearest
shopping center or access to the train station that will provide you
with a lot of ease in moving around. Also, check with the hotel if
they have a large tour groups arrive at the same time. Hotel costs
are higher during periods of high occupancy, and do not have the
flexibility of late check-out. This is an important aspect that, if
ignored, can affect your tour itinerary and your impression of the
level of hotel hospitality.

Prices and Discounts

The hotel rates are a huge factor when it comes to choosing a hotel.
However, paying more does not always mean that you will receive
an equivalent level of service and standards. One way to maximize
the price will check if they are part of an alliance with airlines or car
rental companies, offering customers a discount for their allies.
Sometimes, credit card companies offer their cardholders exclusive
rate for special which can be very interesting. In addition, if it is
possible to use your frequent flyer points to redeem hotel
discounts, this could help reduce the cost of the hotel as well.

Boutique Hotel

Finally, apart from chain hotels, boutique hotels may be a good

alternative for a romantic place for couples or families looking for a
more typical of the theme. Many boutique hotels have less space
but offer value added services such as in-room spa bed, breakfast in
bed or even in-room massages. In the end, your choice of hotel
really depends on what you want from your holiday.

2. travel.
travel

Engineering the distance moved by a mechanical part, such as the stroke

of a piston

Collins Discovery Encyclopedia, 1st edition HarperCollins Publishers

2005
What does it mean when you dream about travel?

There are many possible meanings of travel dreams, including freeing

oneself of obstacles and restrictive circumstances. Dreaming about a
journey can be about our life journey, so how we feel about our dream
journey can reflect how we feel about our lives. A dream journey can also
symbolize something less comprehensive, such as some specific move we
have made in our lives. (See also Voyage).

The Dream Encyclopedia, Second Edition 2009 Visible Ink Press. All
rights reserved.

travel

(mechanical engineering)

The vertical distance of the path of an elevator or escalator as measured

from the bottom terminal landing to the top terminal landing.

McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright

2003 by The McGraw-Hill Companies, Inc.

travel, rise

Of an elevator, escalator, etc., the vertical distance between the bottom

terminal landing and the top terminal landing.

Travel

(dreams)

Many people dream of traveling in planes, cars, trains, or motor bikes.

Traveling seems to be one of the most common dream themes. It is
representative of our journey through life. These dreams could represent
your current movement toward goals or passage through life. Difficult
traveling conditions such as a dark road, a bad storm, or an accident in a
car or other vehicle may be symbolic of the difficulties that we experience
in our daily journey through life. Other times, dreaming about traveling to
a fun place and having a great time could be a form of compensation or
wish-fulfillment. This type of a dream can be an escape from our daily life
and form of transcendence into a beautiful dream world. If you are
constantly having dreams about traveling, take a closer look at the
current situations in your life. Are things going well, or are they more
difficult than you would like them to be? Are your dreams a form of
escapism and entertainment, or are they reassuring you that life is an
adventure and you must keep moving forward?
 3. Basic Tips While Travelling Abroad

Basic Tips While Travelling Abroad

Find tips about baggage, culture, making calls abroad and more...

With the progression in the tourism industry, travelling around the world
has become more affordable. As travelling has become an expression of
leisure and relaxation, people dont only travel for work or business.

Following are some helpful tips to plan well if you decide to travel to a
new country:

Your Identity

Only if you have a proof- identity, you can be known as a recognized

citizen of your home country. While you are travelling or if you are in
another country, you may be asked to present your proof- identity in an
unexpected situation. Hence it is advisable to always carry your passport
or driving license that can help to prove your recognition- citizenship, age,
etc.

Your Suitcases

Check with relevant consulates in your home country before you leave.
Know the right rules from the right source. Your flight operator can
answer queries such as restriction on luggage, what to carry, etc. Every
country is different in their rules and checking procedure. Some countries
do not allow perishable food items on flights. Get your facts clear.

Conclution article about travelling make us happy and knows the beauty
of the world
ARTICLE ABOUT SPORT

Could Basketball Ever Become the Most Popular Sport in

the World?
Josh Martin

Alvaro Barrientos/Associated Press

Much has changed on the global basketball scene since the original Dream Team stormed its way
to Olympic gold some 22 years ago.

The sport is now a fixture in most (if not all) of the countries on Earth. Last season, the NBA
boasted 92 international players hailing from 39 different countries and should feature more on
both counts this fall. Spain, from which five of those aforementioned 92 came, is once again the
epicenter of basketball's biggest event of the summer: the newly rebranded FIBA World Cup of
Basketball.

As far as basketball has come in recent decades, it still has a long way to go to catch up to the
world's pre-eminent sport: soccer. While FIFA's World Cup is a global phenomenon filled with
excitement and drama, with every match beamed into homes across the Seven Seas, FIBA's
version has yet to garner such broadcast clout (only Team USA games have been broadcast on
television domestically thus far).

While FIBA World Cup may never enjoy the same worldwide cachet as the FIFA World Cup,
there are a few signs that basketball is closing the gap on soccer's stronghold as the world's most
popular sport.

Sizing Up the Competition

Matthias Schrader/Associated Press

To be sure, basketball has got its work cut out for it. By just about any measure of popularity
from revenue to viewership to social mediasoccer's lead would seem nigh on insurmountable.
According to the consulting firm A.T. Kearney, basketball, as represented by the NBA,
constituted about 6 percent of the global sports market in terms of revenue generated in 2009, at
2.7 billion Euros. Soccer, on the other hand, swallowed a staggering 43 percent of the market,
with a take of 19.5 billion Euros.

Much has changed in the last five years, though, particularly for basketball.

According to collective bargaining guru Larry Coon, the NBA's latest increase in its salary cap
points to a projected basketball-related income (BRI) of $4.75 billion for the league in 2014-15.
That number could jump considerably in the years to come, thanks in large part to the flood of
revenue that's expected to flow from the NBA's upcoming renewal of its national television
pacts.

For the moment, then, that leaves the NBA slightly behind the English Premier League in total
revenue. According to BBC News' Bill Wilson, the EPL broke the 3 billion markwhich
translates to right around $5 billionfor the first time ever in 2013-14.

Unlike the NBA in basketball, the EPL isn't the only billion-dollar conglomeration in the soccer
world. According to Deloitte, Germany's Bundesliga, Spain's La Liga, Italy's Serie A, France's
Ligue 1, Brazil's Campeonato Brasileiro Serie A and the Russian Premier League all checked in
above $1 billion in revenue as of 2012-13.

And that's not including the 22 other soccer leagues around the worldincluding MLS and the
second-division groups in England, Spain, France, Germany, Italy and Japanthat rake in more
money than does basketball's second-biggest association, Spain's Liga ACB, which brought in
just under 107 million Euros (i.e., a shade over $140 million) in 2011-12, per Spanish outlet
AS.com's Alfredo Matilla and Juan Jimenez (via Wikipedia).

Conclution about article sport : sport good for body and health

ARTICLE ABOUT CULINARY

New Culture & Food

It's often useful to understand or get to know different cultures, traditions

and beliefs of a foreign place. For example, some Arab countries have
preferred dress codes.

A translation dictionary can always help you to learn the language around
you. It's usually appreciated if you can also speak simple words like Thank
you', 'Hello', etc with the locals.
When it comes to food, try to eat healthy meals and not just junk. Most
places offer a variety of options such as restaurants, bars, fast food places
and take-aways which cater for all budgets.

Guide books often contain information about eating out such as where to
go, how much to tip etc...

Communication

Communicating while travelling or settling aboard is one of the important

things that you could be doing. Today, with the advent of the latest
technologies many calling services offer you cheap international call rates
. Hence it's convenient to keep in touch with people. Some countries even
have the benefit of free calling, discounts and offers. So it is easier to stay
in contact with your family or organize a business call while you are
travelling.

Places Around You

Discovering new places is exciting, relaxing and it keeps you occupied

during your free time. Contact a travel agency or a travel planner to guide
you. The internet is a good source to help you with information. Local
newspapers and magazines often have special offers and travelling tips
too.

Conclution : culinary food we can meet in all over the world with many
variation

ARTICLE ABOUT FASHION

1.Curly Hair Care Tips

Curly hair care tips. Curly hair have different types. Big curly hair, curly
frizzy curls up like a sausage that is very circular. Because various types of
this, curly hair has a lot of problems because every person has a curly
pattern that is different.

According YouBeauty, experts do not know clearly why there are many
types of hair. Curly hair care tips too different. But definitely, the shape of
your hair follicle curly-haired, has a bag of curly hair and also hair protein
(keratin) that exist in the base of the hair will affect your hair type. All
hair types will grow twisted, whatever your hair type. Will get curly hair if
its wave number is growing.

Curly hair care tips

Keep the humidity

The owners of curly hair is highly recommended to maintain the hair
moisture. In order for curly hair more smooth and gentle to use a deep
conditioning treatment twice a month. If your hair is dry, do not wash too
often, try to only twice a week.

Be careful Drying
You must be careful to handle curly hair. Avoid using too coarse towel
when drying your hair or wrap your hair with a towel to absorb the excess
water wash.

"Curly hair must be dried slowly, but if your schedule is too dense for it,
wipe with a soft towel and make sure your hair does not fall apart when
rubbed," advises celebrity stylist Kristan Serafino. "If curly hair is touched
with the rough - or worse combed - will cause your natural curly hair
matted instead."

Citing Conectique, you should dry the hair with your fingers, with or
without a fan. The result will make the hair become more organized and
flexible.

Do not touch
When using curl enhancer products like cream, gel or mousse, follow the
pattern of your hair curly, rotate from the middle to the ends of your hair,
advice Serafino. "When hair is dry, then you should apply new silicone
serum on the ends of your hair to soften curly pattern and make it more
shiny," he added.

Once laid out, do not touch your hair again because the more you play,
your hair will actually grow tangled. Thus curly hair care tips, may be
useful for you.

4. Tips to Pick the Ladys Tote

In picking a ladies pack, there must not be constantly simple. Ladies have
their own particular thought and it can be shape, shading, value, and even
shop or the spot that they can purchase. The following are a few tips that I
pick as the reference which may help the individuals who feel confound to
pick a tote.

Shape. Watch your need to pick the right purse. It doesnt entirely
different as you do when you pick sweater in a frosty climate as opposed
to pick night robe. In this way, when you underscore the purse for going to
work, dont pick the sack that equivalent to wedding gathering satchel.

Shading. Each purse more often than not has more than more shading.
Ladies look all the more fascinating about the dark tote in light of the fact
that it is by all accounts more charming and lavish. The dark shading
makes the client turn out to be simple in consolidating with their dress. In
any case, it cant close the likelihood that alternate hues will make the
magnificence and the extravagant of the tote likewise discharged.

Cost. The sack with a high cost is normally has the higher quality. Be that
as it may, that discernment wont generally be correct. You have to
investigate the pack well and dont hang the quality simply taking into
account the cost. There must be numerous excellent purses which
accompany a low cost.

Shop. These days, online shop has got a higher fame instead of logged off
shop. It ready to comprehend in light of the fact that picking a purse in
online shop is dependably be less demanding than disconnected from the
net shop. Yet, you have to guarantee the quality when make a go at
shopping there. Each of us realize that the item in online shop might be
seen from its shading and its shape. While, we cant touch it so the nature
of its material still be strange. Along these lines, be cautious.

5. Fashion Trends for Jewelry 2011

Fashion Trends for Jewelry by: Robert Salvatore A continuing trend that
drives designers picks for fashion colors is the consumers drive for
individuality, fashion, and escapism. People in the market are looking for
jewelry that will make them more fashionable. Sometimes people can go
for a more adventurous and daring piece of jewelry, and sometimes people
can accessorize with subtle jewelry. Whatever the choice is for the day, no
one can go wrong with putting on some few fabulous jewels. If one wants
to pull out an adventurous look, luckily the latest industry predictions for
Spring 2011 show that designers have opted for colors on the opposite
side of the color spectrum. This spring is in it for vivid, bright, and lively
colors. So how can anyone go wrong throwing on a amethyst ring, or a
aquamarine one. Even a black diamond ring can throw off anyones outfit.
Colors are in for this spring. Citrine earrings, blue topaz earrings,
aquamarine earrings, pink sapphires, and smoky topaz earrings can really
brighten up your wardrobe, and you will definitely fall into this seasons
latest trend. Gems are also always enriched with deep and vivid colors,
and at CoutureLineX all of these mentioned colors and jewelry are
available. Remember bright colors are going to make you pop, and there is
no problem looking dazzling this spring. Another popular trend this
season, are the neutral colors that play the backbone for all other colors
to play on. These nude hues leave an honest vibe that makes anyone
relaxed, calm, and approachable. Even gold is trending in this style. Any
type of gold chain, ring, or earrings, can give someone a relaxed style, and
also look very trendy for this season. Smoky Topaz earrings would be a
great example to following this trend, and can be viewed at CoutureLineX.
This light brown gives a haze to ones look, looking fresh and ready for
spring! You can also mix up your look with a garnet and diamond mixed
earring, giving you a fresh look, which is parallel to the neutral colors
giving off this season. Going for a subtler look? No one can go wrong
having a white diamond ring. A regular diamond can give off your
presence in a classy and even a flirtatious way. If diamonds are not your
thing, throw on a classic pearl necklace. Every one should have at least
one pearl necklace in their jewelry box. Having a simple necklace around
your neck wont do you wrong either.
conclution: fashion is the part of our life, fashion make us more confident
and make adorable style.