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By Mohd Salman
What is Epilepsy?
Epilepsy is a neurological affliction in which a person experiences recurrent
seizures. Seizure can be defined as an abrupt rush in the electrical activity of brain
that causes a temporary disruption in communication between brain cells. A person
behaves very differently during a seizure and sometimes becomes unconscious.
There are mainly two kinds of seizures i.e. generalized seizures which affect the
entire brain and the partial or focal seizures which affect only one part of the brain.
Sometimes, it is difficult to diagnose a mild seizure that lasts for a few seconds.
There are numerous reasons for occurrence of seizure that include a high fever,
head trauma, very low blood sugar level, and alcohol withdrawal. Epilepsy is an
unexceptional disorder that affects 65 million people around the world. It can be
developed at any stage of life, but it is more common in young children and old
adults that too in males rather than females. As far as the treatment of epilepsy is
concerned, there is no cure for it but it can be controlled with certain medication
and strategies.
Symptoms of Epilepsy
The main symptom of epilepsy is seizures, although it differs from an individual to
individual on the basis of type of seizure.
Partial seizures
Generalized seizures
This affects the whole nervous system. Different kinds of generalized seizures are:
Clonic seizure- It leads to the repeated jerky movement of face, neck and
arm muscles.
Causes of Epilepsy
There are various causes of epilepsy but in many cases the cause can't be
determined. However, the possible causes are:
Vascular diseases
Cerebral hypoxia ( a condition of lack of oxygen in brain)
Alzheimers disease
Neurological diseases
Diagnosis of Epilepsy
Diagnosis of a disease is very important so that the medication of a patient can be
started on time to improve his/her health conditions. In case of epilepsy, patient's
medical history and symptoms help the doctor to decide which test will be helpful.
The patient undergoes various neurological tests and complete blood count test
with chemistry of blood. Blood tests are used to look for signs of infectious
diseases, kidney and liver function and glucose level in blood.
Treatment of Epilepsy
Treatment of epilepsy completely depends on individual's health, symptoms and
how well the individual is responding to therapy. The main treatment options for
an epileptic person are:
Antiseizure drugs - These are the drugs that can minimize or eliminate the
seizures. These drugs are absorbed by stomach and then reach to the brain through
bloodstream. These affect the neurotransmitter in such a way that reduces the
electrical activity in the brain. Doctors prescribe a single drug or a combination of
drugs depending on the class of seizures. Some commonly used ant seizure drugs
are levetiracetam, lamotrigine, topiramate, valproic acid, ethosuximide and
carbamazepine. These drugs are given in liquid, tablet or injectable form.
Vagus nerve stimulator - It is a device which is kept under the skin on the chest
that stimulates the nerve running through the neck. This helps in preventing the
seizures.
Brain surgery - The part of brain responsible for seizures is either removed or
altered. In most of the cases, a temporal lobe is removed and the process is known
as temporal lobectomy. It stops the seizure activity. Bleeding, infection and a bad
reaction to anesthesia are some of the common risks in a brain surgery.
Is Epilepsy Hereditary?
There are approximately 500 genes that relate to epilepsy. The probability of
inheriting this disease is quite low. The chances of developing epilepsy by the age
of 20 are 1% but it increases to 2-5% in case an individual's parent is epileptic.
There are certain rare conditions, such as tuberous sclerosis and neurofibromatosis
that can cause seizures. These conditions can be transmitted from one generation to
another.
Epilepsy doesn't affect the potential to have children but the antiepileptic drugs can
affect the unborn baby. So a woman on epilepsy medication should consult her
doctor before getting pregnant.
Epilepsy Facts and Statistics
65 million people have epilepsy worldwide in which United States include 3
million people.
The major cause of epilepsy is stroke in the people above 35 years of age.
For 6 out of 10 people, the cause of seizure cannot be determined.
More than half of the people with epilepsy who don't respond to medication
improve with a ketogenic diet.