P.-J.

Raugel

Rapid Food Analysis

and Hygiene Monitoring
Kits, Instruments and Systems

Springer
 TABLE OF CONTENTS

REGISTRED MARKS, TRADE MARKS AND SERVICE MARK XIX

INTRODUCTION ; xxi

FOOD ANALYSIS AND HYGIENE MONITORING KITS, INSTRUMENTS AND SYSTEMS XXIII

TRANSPLANTATION OF ALTERNATIVE METHODS INTO THE AGRO-FOOD INDUSTRIAL CONTEXT. XXIV

THE PRODUCTS ANDTHEIRCOMMERCIALLZATION IN EUROPE .-. XXV

PRODUCTS NOT DESCRIBED IN THIS BOOK (NDITB) XXVI

FIRST PART:
VALIDATION OF METHODS, KITS AND INSTRUMENTS BY
AOAC, AFNOR AND MICROVAL 1
AOAC 3

AOAC INTERNATIONAL, AOAC Research Institute, AOAC Europe -f 3

The AOAC International Official Methods Program 3
The AOAC Peer-Verified Methods Program 5
AOAC Research Institute Test Kit Performance Testing Program 6
Some AOAC International Publications , 10
AFNOR 11

AFNOR, the French Standard Association 11

Introduction 11
ProtocolsforComparison of an Alternative Method
with a Reference Method 12
Conditions of Experimentation 14
THE EUROPEAN MICROVAL PROJECT 16

A Eureka Project 16
Microval in June 1996 (Third Annual Meeting, Brussels) 16

SECOND PART:
DESCRIPTION OF PRODUCTS MANUFACTURED BY 42 GROUPS AND/OR COMPANIES.... 19

ABER INSTRUMENTS 21

Microcyte Portable Flow Cytometer ;.. 21

On-line Determination of Viable Cell Concentrations ..;.... 24
Commercialization of Aber Instruments Products in Europe 24
 Table of Contents

ADVANCED INSTRUMENTS 25

The Dairy and Food Division of Advanced Instruments 25

3 Fluorophos Tests Running on the Same Fluorometer 25
Microprocessor Controlled Detection of Water in Milk 29
Distribution of Advanced Instruments Products in Europe 30
AES LABORATOIRE 31

Some Microprocessor-Controlled Instruments Manufactured by

AES Laboratoire ..: 31
Commercialization of Products of AES Laboratoire in Europe 35
AROMASCAN : 36

Range of Systems for Aroma Sensing and Measurement

Manufactured by Aromascan 36
Commercialization of the Aromascan Products in Europe 38
BlOCONTROL 39

Microbiology Testing Systems Manufactured by Biocontrol Systems 39

Salmonella 1-2 Test Immunodiffusion Screening Method 39
Assurance Enzyme Immunoassays for Detecting Bacteria 44
Visual Immunoprecipitate (VIP) Assays .-. 46
Sample Preparations for Assurance and VIP Assays 48
Chromogenic Determination of Coliforms and E. Coli 49
Distributors of Biocontrol Products in Europe 52
BIOMERIEUX 53

The Bactometer System of Impedance Technology 53

The Vidas System of Automated Immunoanalysis 60
The Vitek Automated Identification System 79
Mini-API System and Identification Strips 82
Connections of the Bactometer, Vitek and Vidas Systems 85
Commercialization of bioMerieux Products in Europe. 85
BOEHRINGER MANNHEIM 86

Manufacturing Activity of Boehringer Mannheim Biochemica 86

Perid-TestTeststrips for Detection of H2O2 87
Test Combinations 88
The 35 Test Combinations Kits 92
AOAC International Validations 148
Commercialization of Boehringer Mannheim Products in Europe 149
CELSIS*LUMAC 150

The Celsis*Lumac Group 150

Instruments, Kits and Systems Manufactured by Celsis*Lumac 150
Principles of ATP-Bioluminescence Assays 152
ATP-Based Portable Contamination Monitoring Systems '. 153
Celsis Luminometers >.-.... 155
 Table of Contents XI

Celsis ATP Bioluminescence Based Reagent Systems Kits 155

Lumac Range of Luminometers ;.... 163
The 2-Place Lumac Filtration System 164
Lumac ATP Bioluminescence Based Reagent Systems Kits 164
Expertises of Lumac ATP Bioluminescence Based Systems 171
Celsis Digital System 175
Screening Raw Milk for Presence of Antibiotic Residues 176
Detection of Salmonella Using Immunochromatography 177
Commercialization of Celsis*Lumac Products in Europe 179
CHROMAGAR 181

Range of Manufactured Products ....... 181

Determination of Escherichia Coli and Other Coliforms 182
Detection and Enumeration of Staphylococcus Aureus 184
Commercialization of Chromagar Products in Europe 185
COKTECS DIAGNOSTICS 186

Range of Products Manufactured by Cortecs Diagnostics 186

Quantitation and/or Detection of Mycotoxins 187
Quantitation and/or Detection of Protein Additives 193
Qualitative Meat Species Testing 202
Commercialization of Cortecs Diagnostics Products in Europe 212
DIFFCHAMB.. .J. 213

The Diffchamb Group 213

Products Manufactured and/or Developed by the
Diffchamb Companies 213
Control of the Thermic Treatments 215
Immunoenzymatic Detection of Micro-Organisms Using Plates 217
Immunochromatographic Detection of Micro-Organisms Using Card... 223
Immunoenzymatic Detection of the Staphylococcal Enterotoxins 226
Immunoenzymatic Determination of Aflatoxin B, 231
Immunoenzymatic Determination of Gluten 234
Immunoenzymatic Detection of Histamine in Fish 238
Immunoenzymatic Dosage and/or Detection of Triazines.... 242
Automated system for Elisa Tests Management : 246
Commercialization of Diffchamb Products in Europe 247
DONWHITLEYSCIENTIFIC 248

Automated Impedance Microbiology : 248

Automatic Plater for Enumeration of Micro-Organisms 255
Commercialization of Products of Don Whitley Scientific in Europe 257
DYNAL -.. 258

The Company .". 258

Products Manufactured for Biomagnetic Separation 258
Principles of the Dynabeads for Microbiology 258
XII Table of Contents

Dynabeads Anti-E. Coli O157, Anti-Salmonella and Anti-Listeria 261

Performances Claimed by Dynal 264
AFNOR Validations of the Dynabeads for Microbiology 266
Expertises of the Dynabeads for Microbiology :, 269
Commercialization of the Dynal Products in Europe 271
EAC i 272

The Colorimetric Fresh Tester Method Developed by EAC 272

Distributor and Other Sellers of FTP Kits in Europe 274
EDITEK .-?: 275

Addresses f. 275
Ranges of Kits of Diagnostics Manufactured by Editek 275
Card Tests for On-Site Screening of Mycotoxins and Antibiotics 276
Immunodiagnostic Tests for Quantitative Results 278
Laboratory Screening of Antibiotics, Mycotoxins and Hormones 281
Raw Meat Species Identification 291
Commercialization in Europe of the Kits Manufactured by Editek 294
E.MERCK 295

Kits, Instruments and Systems for Food Analysis Manufactured by

L. Pro/UBA Department of E. Merck 295
Two Culture Methods for Bacteriological Analysis 296
The Bioquant Range of Enzymatic Kits ^. 301
Instruments for Chemical and Biochemical Analysis 313
Commercialization in Europe of the
I Food Analysis Kits and Instruments Manufactured by E. Merck 314
EURO-DlAGNOSTICA 315

Immunological Products Manufactured by Euro-Diagnostica 315

Microtiter Plates for the Detection of Drug Residues 315
Tube Test for On-Site Detection of p-Agonists 320
Immuno affinity Chromatography for Cleaning-Up Samples 321
Commercialization of the Euro-Diagnostica Kits in Europe 322
FARM-TEC 323

Test of Grain Germinative Capacity 323

Commercialization of the Farm-Tec Instruments 324
Foss ELECTRIC 325

Ranges of Products Manufactured by Foss Electric 325

The Multicomponent Infrared Analysers: Introduction 326
The Infrared Analysers of Milk and Dairy Products 328
A Multicomponent Infrared Analyser of Grain 335
A Multicomponent Infrared Analyser of Raw Meat 336
Fossomatic Range of Somatic Cell Counter in Raw Milk 338
Automatic Counting of Viable Bacteria in Raw Milk 342
 Table of Contents

Systems of Central Milk Testing 346

The EiaFoss Enzyme Immuno-Assay System 348
Commercialization of the Foss Electric Products in Europe 350
GEN-PROBE 351

The Gen-Probe Accuprobe Range of Assays 351

European Distributor of the Accuprobe Kits 358
GENE-TRAK SYSTEMS 359

The 7 Gene-Trak Assays 359

Samples Preparations and Enrichments 364
AFNOR Validations 367
AOAC International Validations '. 370
Expertises and In-House Evaluations of the Gene-Trak Assays 372
Gene-Trak System's Distributors in Europe 378
HUGHES WHITLOW 379

The Bioprobe System Manufactured by Hughes Whitlock for

Hygiene Control and Food Testing 379
Commercialization of the Bioprobe in Europe 384
HY-LABS -... 385

The Hy-Giene Monitors Manufactured by Hy-Labs 385

Distributor of the Hy Labs Kits in Europe 386
INCELTECHLH-SGI 387

Products Manufactured by Inceltech 387

Glucose and Lactate Analyzer with Biosensor: Microzym-L -s 387
Commercialization of Inceltech Products in Europe 389
INTERNATIONAL DIAGNOSTIC GROUP .; 390

Products Manufactured by International Diagnostic Group (IDG) 390

The Malthus System Developed by Malthus Instruments 390
Principles 391
The Malthus System 392
Performances of the Malthus System 397
Commercialization of the Products of IDG in Europe 406
MlLLIPORE 407
Development and Manufacturing Activities of Millipore 407
Membrane and Vacuum Systems of
Aqueous Samples' Preparation and Analysis 407
Detection of Viable Micro-Organisms in Aqueous Fluids 411
Direct Epifluorescent Filter Techniques (DEFT) 413
ColiSure: Detection of Coliforms in Drinking Water 415
Commercialization of Millipore Products in Europe ...' 418
XIV Table of Contents

NEOGEN 419

Kits for the Detection and the Determination of

Mycotoxins Manufactured by Neogen 419
AOAC Validation and Test of Performance 425
Distribution of the Kits of Neogen in Europe 427
NEWPORT SCIENTIFIC 428

Viscometers Manufactured by Newport Scientific 428

Distribution of the Rapid Visco Analysers in Europe 433
ORION DiAGNOsncA 434

4 Hygicult Agar-Slide Tests for Hygiene Control 434

Distribution of Orion Diagnostica Products in Europe 435
PERCEPTIVE INSTRUMENTS 436

Automatic Colony Counting System 436

Commercialization of Products of Perceptive Instruments in Europe 438
PERTEN INSTRUMENTS 439

The Percon Product Line of Spectrophotometers 439

The Determination of the Alpha-Amylase Activity 442
The Glutomatic System for Gluten Determination 446
The Single Kernel Characterization System 453
Commercialization of the Perten Instruments Products in Europe 455
PROMEGA 456
The Enliten Range of Bioluminescence-Based Kits for
Hygiene Control and Food Testing 456
3 Qualitative Tests for Controlling Hygiene 457
Detection of Living Yeasts and Molds 462
Measurement of Milk Microbial Quality 464
Distribution of the Enliten Range of Kits in Europe 467
QUALICON 468

Genetics-Based Products Manufactured by Qualicon 468

Basic Principles of the Bax PCR-Based Methods for
Screening Bacteria and Confirming Suspect Colonies 468
PCR-Based Method for Screening Pathogenic Bacteria 469
PCR-Based Method for Confirming Suspect Colonies 474
Automated Microbial Characterization System 477
Qualicon Products in Europe: Riboprinter for Typing Service 485
QALIFESCIENCES 486

The Iso-Grid System Developed by QA Life Sciences 486

Performances of Iso-Grid Methods Claimed by QA Life Sciences 493
AOAC International Validations of Iso-Grid Methods 495
Distribution of Qa Life Sciences Products in Europe 499
 Table of Contents XV

R-BlOPHARM 500

Products Manufactured by R-Biopharm 500

Immunoassays and Column for Analysis of Aflatoxins 503
Immunoassays and Column for Analysis of
Mycotoxins Other than Aflatoxins 507
Immunoassays and Column for Analysis of Anabolics/Hormones 514
Immunoassays for Analysis of Antibiotics 529
Immunoassays and Enzyme Binding Assay for Analysis of Vitamins 535
Immunoassays for Analysis of Seaweed-Toxins 541
Immunoassays for Analysis of Environmental Parameters 542
Assays for the Detection of Staphylococcus Aureus and Its Enterotoxins 543
Assays for the Detection of Cow's Milk 546
Immunoassayfor Analysis of Gluten 549
Immunoassay for Detection of Genera'iAspergillus and Penicillium 552
Commercialization of R-Biopharm Products in Europe 554
SARTORIUS 555

Products for Microbiological Testing of Foodstuffs and

Water Manufactured by Sartorius 555
Detection and Enumeration of Airborne Bacteriophages in Dairies 555
Commercialization of Sartorius Products in Europe 557
SCETI 558

Enzyme Immunoassay Kits Manufactured by Sceti 558

Quantitative Detection of Antibiotic and Sulfur 558
Detection of Okadaic Acid, Diarrhetic Shellfish Poison 563
Distributors of Sceti Products in Europe 564
SY-LAB 7. 565

The BacTrac Analysers Based on Automated Impedance 565

Principles 566
The Components of the BacTrac System 568
Applications : 569
Performances of the BacTrac System 578
Commercialization of the BacTrac System in Europe 580
SYNOPTICS 582

Automatic Colony Counting for Microbiology 582

Commercialization of Products of Synoptics in Europe 583
TECRA DIAGNOSTICS 585

Immunoassay Test Kits and Associated Products

Manufactured by Tecra Diagnostics 585
7 Tecra Visual Immunoassays (Via) Kits 586
Tecra Immunocapture System for Improving Isolation of Bacteria 606
Tecra Unique Using Immunoenrichment 609
Sample Preparation for Immunocapture and Unique 612
XVI Table of Contents

Commercialization of Tecra Diagnostics Kits in Europe 613

3 M MICROBIOLOGY 614

Principles and Apparatus of Petrifilms 614

Petrifilm Assay Procedures... 617
Petrifilms: Interpretation 619
AFNOR Validations of Petrifilms 623
AOAC International Validations of Petrifilms 632
NMKL Validations of Petrifilms 636
Expertises of the Petrifilm Aerobic, Coliform, E. Coli and
Yeast/Mould Count Plates 637
HEC Kit for Screening for Escherichia Coli Oi57:H7 644
Commercialization of 3M Microbiology Products in Europe 647
VICAM rC. 649

Ranges of Testing Systems Manufactured by Vicam 649

Immuno-Affinity Based Mycotoxins Testing Systems 649
Microbiological Tests Using Immunomagnetic Capture 656
Distributors of Vicam Products in Europe 664

THIRD PART:
QUOTED EXPERTS AND IMPORTANT JOURNALS USED IN THIS SURVEY 667

REFERENCES OF THE QUOTED EXPERTS 669

IMPORTANT JOURNALS USED I N THIS SURVEY 684

FOURTH PART:
2 4 8 COMMERCIAL SUBSIDIARIES, DISTRIBUTORS, SALES AGENTS AND
POINTS OF SALES IN 3 0 EUROPEAN COUNTRIES 687

AUSTRIA 689

BELGIUM 696

CROATIA 702

CYPRUS 703

CZECH REPUBLIC 705

DENMARK 709

ESTONIA 715

FINLAND 716

FRANCE 721

GERMANY 743
 Table of Contents XVII

GREEa 758

HUNGARY 763

ICELAND : 766

IRELAND 767

ITALY 770

LATVIA 782

THE NETHERLANDS 783

NORWAY 793

POLAND 797

PORTUGAL r....^. 801

ROMANIA 807

RUSSIA 808

SERBIA 811

SLOVAKIA , 812

SPAIN 814

SWEDEN 823

SWITZERLAND 829
j

TURKEY ^ 835

UKRAINE 839

UNITED-KINGDOM 841

INDEXES 869

PREFATORYNOTESTOTHE INDEXES 871

OFFICIAL APPROVALS, REVIEWS AND VALIDATIONS 872

METHODS, MATERIALS, TECHNIQUES AND INSTRUMENTS 873

ANALYTES, PARAMETERS, OTHER TARGETS OF THE ANALYSIS AND

COMPETITORS, COMPETITORS AND INTERFERENCES 888

PRODUCTS AND ENVIRONMENTS ANALYZED, MATRIXES .:. 906