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102. Name and Address of the Institute/organisation where the project will be
implemented.
City : Kavali
Pin Code : 524201
State : Andhra Pradesh
Telephone No : 08626 -243930
Fax : 08626 -243930
E-mail : vitsaim1998@gmail.com
Mobile No : 9849172028
107. Co-Investigator : Dr. D. Prathyusha Reddi
Designation : Professor
Category : General
Institute Name : PBR Visvodaya Institute of
Technology and Science
Address :
City : Kavali
Pin Code : 524201
State : Andhra Pradesh
Telephone No : 08626 -243930
Fax : 08626 -243930
E-mail : vitsaim1998@gmail.com
Mobile No : 9849172028
201. Introduction
The proposal originates from the recent reports and the necessity of the
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Cancer is the second leading cause of mortality in developed countries after cardiovascular
disease. .
3
Currently, chemotherapy is the most important treatment for cancer and the ultimate goal
is to destroy the cancer cells without any harmful effect on the normal cells. Within the
past decade, advances in our understanding of the cell cycle have presented new targets
that may allow for the development of more selective chemotherapeutic agents agents
that target only cancer cells. Cancer chemotherapy has achieved significant success
through the discovery of various new drugs. However these drugs cannot completely
eliminate tumours in the human body and also show side effects and toxicity. Despite this,
the discovery of most potent anticancer agents had challenging issue in cancer
chemotherapy for the future generations.
In phenothiazines, the proton on the nitrogen atom was acidic. So large number of
phenothiazine analogues (Figure1) are expected through nitrogen atom either aliphatic
chain or hetero atoms cyclic chain. Some of the phenothiazines bearing pyrazole unit
and benzoyl unit (partial analogues of phenstatin with a phenothiazine) on the
nitrogen atom exhibit in vitro cytotoxic activity inhibiting the growth of HCT-116, LOX
IMVI, SK-MEL-5 cell lines and COLO-205, A498, and MCF7 cell lines.4- 6
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203. Objectives
Our objectives of the proposed project are:
204. Methodology:
1. Target population and sample size to be covered
NA
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NA
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From the present work, we will be engaged with development of biologically active
new heterocyclic systems such as isoxazoles, triazoles, and pyrazoles. Further all the
synthesized molecules are screened for different pharmacological activities including
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antitumor and anti tuberculosis activities. All the synthesized compounds will have
the commercialization capabilities.
NA
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A. Recurring
1) BUDGET FOR SALARIES/WAGES
Budget In Rupees
Designation& Monthly 1 year
st
2 year
nd
3 year
rd
Total
number of emoluments
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persons
Research 6,00,000 6,00,000 6,00,000 18,00,000
25,000
Associate Two (24) (24) (24) (72)
1,80,000 1,80,000 1,80,000
JRF- One 15,000 5,40,000
(12) (24) (24)
Lab Assistant- 1,20,000 1,20,000 1,20,000
10,000 1,20,000
One (12) (12) (12)
Total 3,00,000 3,00,000 3,00,000 9,00,000
2) Consumables
Budget In Rupees
Item Quantity 1st year 2nd year 3rd year Total
Microstrip patch 1No
1,50,000 1,50,000 57,000 3,57,000
antenna (10x10)
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110Nos
TR modules @Rs.
per
2,31,000/-
one TR
1,00,00,000 1,00,00,000 54,10,000 2,54,10,000
module
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In order to carry out the design and simulations of antenna and feeder network
a tailored versions of the RF software will be procured. This will be used during 1 st
year and later it can be used by the institute for future projects. Further, a network
analyzer/ a spectrum analyzer is required in the 2nd year to carry out the pattern/
spectrum measurements on the antenna, feeder network and TR modules. This need to
be imported and these instruments are not being manufactured in India.
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6. Whether PI would avail sabbatical leave for more than 6 months during the
project.If so, the name of the Co-PI.
No
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8. Whether staff salary as per DST/Host Institute norms; If salary as per norms of
host institute, certificate from host institute to be attached
Not Applicable
National
13 LabVIEW software (10-users Licence ) 6,00,000 1
Instruments
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ANNEXURE: 1
Experience:
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Professional achievements:
Honours:
Specific Contributions:
Lead the team for preparing the study report on realisation of Multi
Object Tracking Radar (MOTR)
A subscale version of Multi Object Tracking Radar was realised and
successfully commissioned.
Realised and commissioned C-band and S-band radars.
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Developed the abort and acceptance criteria and implemented the same
for Acoustic Emission monitoring during proof pressure testing of rocket
motor cases.
Developed a two-channel Acoustic Emission Monitoring system, which
can be used for weld monitoring.
Developed a source location algorithm to detect cracks in metallic
structures using acoustic emission technique.
Realized and commissioned state of the art Instrumentation systems for
performance testing of rockets and subsystems.
As Project Director, MOTR contributed significantly in realizing
Indigenous Multi Object Tracking Radar first time in India. The Radar is
commissioned and made successfully operational.
[2].Subba Rao S.V, Srinivasan K.V, Annamalai .M" Instrumentation for high
frequency signals form Acoustic Emission sources", National Symposium on
Instrumentation (NSI-11), Hyderabad, October 1-4, 1986.
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[8].Subba Rao S.V,Srinivasan K.V, Annamalai .M and Devaraju K.V.M, "A Real
Time Token Ring LAN for AE monitoring", 10 th International Acoustic
Emission symposium, Sendai, Japan, October 22-25, 1990.
[13]. Subba Rao S.V, Bhat M.R, Jayakumar.T. Guide To Non-Destructive Testing,
Publications of Indian Society for Nondestructive testing, 1994.
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[18]. Subba Rao S.V, Jayaseelan D., Satyanarayana. N, Visvanathan .K, "Acoustic
Emission monitoring of a long stored Rocket Motor Case", 14 th World
conference on NDT (14th WCNDT), New Delhi, December 22-28, 1996.
[20]. Subba Rao S.V, Jayaseelan .D,Madhusudhana Rao K., Murthy CRL,
"Modern Trends in AE Instrumentation", Fourth National Workshop on
Acoustic Emission (NAWACE-97), Mumbai, August 22-23, 1997.
[22]. Subba Rao SV, Proof Pressure Testing of PSLV/GSLV rocket motor
hardware- a review, ISRO Technical symposium, Bangalore, September
13,2001
[23]. Subba Rao S.V, Sensors, Signals conditioning and data Acquisition for
Acoustic Emission testing", Proceedings of fifth National workshop on
Acoustic Emission (NAWACE-2002), Hyderabad, October 18-19, 2002.
[24]. Subba Rao S.V, "Attenuation of Acoustic Emission signals in Maraging steel
hardware", National seminar on NDE-2003, Thiruvananthapuram, December
11-13, 2003.
[25]. Subba Rao S.V, Signals and Data acquisition for NDE, National Seminar
on NDE-2005, Kolkata, December 30-31, 2005.
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[30]. Subba Rao BV, Gopala Krishna J, SrinivasaBabu M, Subba Rao SV, Seshagiri
Rao V, Prasad MYS, Design considerations for realization of Multi Object
Trcking Radar (MOTR) for space applications Proceedings of Second IEEE
International conference on RF and signal processing systems (RSPS 2010),
KL University, Guntur, January 7-9, 2010.
[32]. Prasad MYS, Seshagiri Rao V, Subba Rao SV, Subba Rao BV, Requirements
of Indian Space Research Organisation for a Multi Object Tracking Radar
61st International Astronautical Congress(IAC 2010), Prague, Czech
Republic, 27 September-1 October, 2010.
[33]. Naga Prasanna B, PhaniSrinivas M, Subba Rao SV, Subba Rao BV, Design
of1X4 Microstrip Patch Antenna and evaluation of its Performance,
National Conference on signal processing and communications (SPCOMs
2011),Guntur, 1-2 April, 2011.
[34]. Subba Rao SV, Subba Rao BV, Prasad MYS, Seshagiri Rao V,
Configuration and design options to monitor GSO space debris by Multi
Object Tracking Radar of ISRO, 63rd International Astronautical
Congress(IAC 2012), Naples, Italy, 1-5 October, 2012.
[36]. Subba Rao BV, Gopala Krishna J, SrinivasaBabu M, Subba Rao SV, Seshagiri
Rao V, Prasad MYS, Design, development and qualification of MOTR
subscale system Proceedings of National conference on space debris
management and mitigation techniques, Bangalore, February 27-28,2014.
[39]. Raghu Kumar S, Velayudham K, Subba Rao SV, Seshagiri Rao V, Digital
Workflow Systems for ISRO A Systems Approach for e-Governance ISRO
seminar on computers and Information Technology (ISCIT-2015),
Thiruvananthapuram, March 19,2015.
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Academic Qualifications:
Experience
Publications List
ANNEXURE: 2
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