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ClinicalPearls,MemoryAids,
Mnemonics,andaFewSmiles
BryanL.Burke,Jr.,MD,FAAP
UniversityofArkansasforMedical
University of Arkansas for Medical
SciencesandArkansasChildrens
Hospital
Disclosures
Ihavenothingtodisclose.
Idohavesomethingstoconfess,butthismay
notbetheappropriatevenue
1
3/12/2012
HowPeopleThinkisInteresting
Somedoctorsexpressedconfusionovermy
requestforclinicalpearls,memoryaids,and
tf li i l l id d
mnemonics Idontthinkthatway.
Somedoctorswerethrilledtosharetheir
favoriteones Iusethemallthetime.
Agoodpsychologistcouldprobablyexplain
A good psychologist could probably explain
thedifferentthoughtpatterns.
Ifallintotheusethemallthetimecamp.
Memory AsTimeGoesBy
Memory
Itisfortunatethatourclinicalacumenimprovesin
direct proportion to our inability to remember what
directproportiontoourinabilitytorememberwhat
wejustread.
FromMurrayFeingold,MD,ProfessorofPediatricsat
BostonUniversityandPhysicianinChiefatthe
NationalBirthDefectsCenterinBostonandthe
Joseph F Kennedy Memorial Hospital for Children in
JosephF.KennedyMemorialHospitalforChildrenin
Boston.
2
3/12/2012
OneThingtoWhichDr.FeingoldCould
NotGetAccustomed
Certainacademictypeswho,althoughthey
h
haveneverbeenoutintherealworld,
b t i th l ld
continuallypuffontheirpipes,stareatthe
ceiling,andslowlybutpedanticallypontificate
andcriticizethephysicianinpractice.
Dr.FeingoldsThingsthatNever
Change
Quotinganarticlethatispoorlydocumented
b t
butagreeswithyourclinicalimpression.
ith li i l i i
Findingfaultwiththemethodologyor
statisticalanalysisofanarticlethatdoesnot
agreewithyourclinicalimpression.
You
Youaremorelikelytogetintotrouble
are more likely to get into trouble
clinicallywhenyoustartfeelingtooconfident
aboutyourdiagnosticabilities.
3
3/12/2012
TheNewLanguageofMedicine
Patientsarecustomersorconsumers.
Doctorsandnursesarehealthcareproviders.
Thesewordsdemeanpatients,doctors,and
nurses.
Thesewordsareeconomicandreductionistic.
Thesewordsendangertheessenceof
medicine.
TheNewLanguageofMedicine
Customersmustrelyoncaveatemptor let
th b
thebuyerbeware.
b
Suchasentimentfostersanadversarial
relationship notoneoftrust.
Makesamockeryofthebondbetweenthe
healer and the sick
healerandthesick.
4
3/12/2012
TheNewLanguageofMedicine
Patientderivesfrompatiens,tosufferorbearan
affliction.
affliction
Doctorderivesfromdocere,toteach.
Nursederivesfromnutrire,tonurture.
Thenewwordsignoretheessentialpsychological,
spiritual,andhumanisticdimensions thevery
thingsthatmakemedicineacallingandnotajob.
hi h k di i lli d j b
Essentially theperfectscreenfor
Essentially
ignorance
Question Howdothelungssound?
Answer
A E
Essentially,clear.
ti ll l
Essentiallyisusedmedicallyasascreenfor
uncertainty.
TheresponsetoDoyoulikeRazorbackfootball?
wouldneverbeEssentially,yes.,becauseboth
partieswouldbehearingandspeakingEnglish,
i ld b h i d ki E li h
withoutobfuscation.
NP Christy. English is Our Second Language NEJM 300:979,
1977.
5
3/12/2012
VitalSignsandThermodynamics
Patientswhoarereportedtonothavea
t
temperatureviolateabasiclawof
t i l t b i l f
thermodynamics.
Perhapsequivalenttopatientswhodonot
haveanelevatedtemperature.
PatientPresentationAdvice
Whenyoubegintopresentthephysical
examinationfindings,thefirstwordsoutof
i ti fi di th fi t d t f
yourmouthshouldbethepatientsvitalsigns.
Iftheywereunimportant,theywouldbe
calledinconsequentialsigns.
FromThomasDungan,PediatricCardiologist
g , g
atArkansasChildrensHospital,1977.Advice
giventomeasaJMS,duringaparticularly
poorpatientpresentationonmypart.
archildrens.org arpediatrics.org uams.edu
6
3/12/2012
PenicillinAllergyintheFirstYearofLife
Everychildlessthan1yearoldpurportedto
h
haveapenicillinallergyhadacaseof
i illi ll h d f
roseola.
FromJ.O.Cooper,anElDorado,Arkansas
GeneralPediatrician,early1960s,asrelayed
byDaleDildyMD,anACHGeneralPediatrician
y y ,
2011.
DealingwithUncertaintyWhile
MakingaDifficultDiagnosis
AlwaystellthepatientIdontknowthe
di
diagnosisyet.
i t
Tellsthetruth.
Conveysconfidencethatthediagnosiswillbe
found.
Conveyshope
Conveys hope incrediblyimportant.
incredibly important
FromNewtDildyMD,aNashville,Arkansas
familydoctor,early1960s.
7
3/12/2012
AbbreviationEngenderedConfusion
Dontswabachildssorethroatifthe
epidemiologyandclinicalsettingareviral.
id i l d li i l tti i l
10%arecarriersforGroupAStrepsoyoull
justbetreatingfolkswithaviralpharyngitis.
TheabbreviationinPenVK(PenicillinV
Potassium) oralpenicillin
Potassium) oral penicillin doesnotstand
does not stand
forviruskiller.
DanMcGee,again.
HoarsenessandSoreThroats
Neverswabthethroatofanyonewhoishoarse.
Hoarsenessandlaryngitisarealwayscausedby
H dl iti l db
viruses neverbyGroupAStrep.
Thepatientdoesntneedtocometotheoffice,pay
forthevisitandthethroatswab,payforthe
penicillin,andriskStevensJohnsonsyndrome.
TomEdTownsend,GeneralPediatricianand
T Ed T d G l P di i i d
ArkansasSeniorPediatrician,PineBluff,Arkansas,
1979.
8
3/12/2012
KeepingUpWiththeLiterature
KeepingUpWiththeLiterature The
CircleofAcademicLife
MedStudent Readsentirearticlebutdoes
notknowwhatanyofitmeans.
tk h t f it
Intern Usesjournalasapillowduringnights
oncall.
Resident Wouldliketoreadentirearticlebut
eats dinner instead
eatsdinnerinstead.
ChiefResident Skipsarticlesentirelyand
readstheclassifieds.
KeepingUpWiththeLiterature The
KeepingUpWiththeLiterature
CircleofAcademicLife
JuniorAttending Readsandanalyzesentire
articleinordertopimpmedicalstudents.
ti l i d t i di l t d t
SeniorAttending Readsabstractsandquotes
theliteratureliberally.
ResearchAttending Readsentirearticle,
reanalyzes statistics and looks up all
reanalyzesstatistics,andlooksupall
references,usuallyinlieuofsex.
9
3/12/2012
KeepingUpWiththeLiterature The
KeepingUpWiththeLiterature
CircleofAcademicLife
ChiefofService Readsreferencestoseeifhewas
cited anywhere
citedanywhere.
PrivateAttending Doesntbuyjournalsbutlooks
forarticlesthatmakeitintoTime orNewsweek.
Emeritusattending Readsentirearticlebutdoes
notunderstandwhatanyofitmeans.
TAILSforMicrocyticAnemia
Thalassemia
AnemiaofChronicDisease
IronDeficiency
Leadpoisoning
Sideroblasticanemia
FromChristineBarrettMD,ChiefResidentat
ArkansasChildrensHospital,2011.
10
3/12/2012
PMS&Nephritic/Nephrotic
PMS&Nephritic/Nephrotic Syndrome
withDecreasedComplementLevels
PMS Youaredepressedwhenyouhave
PMS
PMS.
Poststreptococcalglomerulonephritis
Membranoproliferativeglomerulonephritis
SystemicLupuswithnephritis.
ChristineBarrettMD,ChiefResidentat
ArkansasChildrensHospital 2011.
BestOpeningParagraphinaLetter
fromaConsultanttoaReferringMD
Thankyouverymuchforthereferralof___,indeed
a complicated patient who history reminds me of in
acomplicatedpatientwhohistoryremindsmeof,in
itscomplexity,ayoungmanwhomIhadthedutyof
caringforincollaborationwithoneofthe
endocrinologistsat___hospital.Hefinallysaidto
meIhavedecidedthatifwhenIdieIgotoheaven,
Godwillexplain
p ___tome.Ontheotherhand,ifI
,
gotohell,Godwillmakemetakecareof___.
SourcecannotberevealedbutIstillhavethe1993
letter BryanBurkeMD.
11
3/12/2012
TheSixHyposofNewbornMetabolic
Acidosis
Hypothermia
Hypoglycemia
Hypoxia
Hypoperfusion
Hypoantibioticemia
Hypoenzymosis
FromRobertArringtonMD,Arkansas
ChildrensHospitalNeonatologist,late1970s.
archildrens.org arpediatrics.org uams.edu
TheNineBloodVesselsInvolvedina
Nuchal Cord
Umbilicalvein,2umbilicalarteries,2external
j
jugularveins,2internaljugularveins,and2
l i 2i t lj l i d2
carotidarteries.
Bytheway,whatisatightnuchalcord?
Explanationofthepathophysiology.
Howthisexplanationhelps.
How this explanation helps
FromRobertArringtonMD,Arkansas
ChildrensHospitalNeonatologist,2005.
12
3/12/2012
AcuteTreatmentofHypokalemia
AcuteTreatmentofHypokalemia
SeeaBigKDrop
Calciumgluconate Kayexelate
Alb t l
Albuterol Diuretic(potassium
Di ti ( t i
Bicarbonate wasting)
Insulin Dialysis
Glucose
SOARtoEvaluateEars
See canyouseetheeardrum.Dowhatisneeded
to get a good view
togetagoodview.
Ossicles poorlyseenthedrumislikelybulging.
Wellseenitslikelyretracted.
Air ifpresentyouknowtheresaneffusionbecause
airandwaterareinterfacing.
Red
R d leastimportant.Brilliantredwithangry
l i B illi d ih
injection?Whiteoryellowduetopus?
BethSimpsonMD,GeneralPediatrician,Childrens
MercyHospitalinKansasCity,2011.
archildrens.org arpediatrics.org uams.edu
13
3/12/2012
SLUBI theoverlookedpartofthe
SLUBI
differentialdiagnosis
SLUBI Selflimitedundiagnosedbenign
illness.
ill
Lotsofweirdthingsjustgoawaywithoutus
everfiguringoutwhattheyare.Itsgoodto
haveanameforit.
ThomasNewmanMD,GeneralPediatrician
Thomas Newman MD General Pediatrician
andResearcherextraordinaire,Universityof
California SanFrancisco,2011.
TheSecretofLookingLikeaSmart
Doctor
Bethethirddoctortoevaluatethechild.
Generallytakesabout2weekstogettothethird
doctor.
95%ofkidsgetwellbythennomatterwhatyoudo,
sowhateveryoudoyoulllooksmart.
Forthatother5%,theylldeveloparash,cough,
fever,bloodydiarrheaorsomethingthatwilllead
youtothecorrectdiagnosis thusyouwilllook
smarterthanthefirst2docswhosawthechild.
14
3/12/2012
TheSecretofLookingLikeaSmart
Doctor
Thatswhywe(privatepracticepediatricians)so
frequently look better than the family practice or ER
frequentlylookbetterthanthefamilypracticeorER
docfromwhomthechildfirstsoughtcare.
Thatswhyacademiccenterssofrequentlylook
betterthanpediatriciansinprivatepractice bythe
timethepatientgetstheretheyareeitheraboutto
get well or so sick you can figure out what they have
getwellorsosickyoucanfigureoutwhattheyhave.
TomEdTownsend,GeneralPediatricianand
ArkansasSeniorPediatrician,PineBluffArkansas,
mid1980s.
TheMostUnderusedDiagnosticTool
Time.Ifthepatientisstable,watchthediseases
progress Inaddition
progress. In addition
RepeatingyourH&Palwaysrepresentsagood
investmentofyourtime.Newsymptomsandsigns
willoccur,orthepatientmayremembersomething
theyhadforgotten.Nothingelsewillgetyoutothe
right diagnosis as quickly and you wonttordera
rightdiagnosisasquickly,andyouwon order a
bunchoffoolexpensiveteststhatwonthelpthe
patientandmayharmthem.
Dr.Townsend,again.
15
3/12/2012
VITAMINSPApproachtoDecreased
VITAMINS
LevelofConsciousnes
LevelofConsciousnes
Vascular Intussusception 30%
I f ti
Infectious have decreased LOC as
havedecreasedLOCas
Toxins thefirstsign.
Accidents Neoplasm
Metabolic&Migraine SyncopeandSeizures
Psychiatric
From an article I cant find, read many years ago Bryan Burke.
TMP/SMXDosingandShakespeare
TMP/SMXDosingandShakespeare
WhoSaysIambicPentameterisDead?
ThecorrectdoseforliquidTMP/SMX One
t
teaspoontwiceadayforeverytenkilosyou
t i d f t kil
weigh.
Nevermorethatfourteaspoonstwiceaday,
asthatequalsanadultTMP/SMXDStablet.
BryanBurke,JuniorMedicalStudent,Arkansas
Bryan Burke Junior Medical Student Arkansas
ChildrensHospital,1977.
16
3/12/2012
CRASHF:TheDiagnosticSecretof
CRASH
KawasakiSyndrome
C Conjunctivitis
R Rash
A Adenopathy,cervical.
S Strawberrytongue.
H Handsandfeet,swollenandthenpeeling.
F Feverfor5days.
FromCarrieDrazbaMD,GeneralPediatrician
atRushChildrensHospital,Chicago,2011.
archildrens.org arpediatrics.org uams.edu
HomeDeliveryandWaterBirths
HomeDeliveryisforpizza.
WaterBirthsareforwhales.
FromMarilynEscobedoMD,Universityof
OklahomaNeonatologist,2011.
FromthesetwoopinionsaloneIcouldbe
convinced to vote for her for President such
convincedtovoteforherforPresident such
commonsenseisneededinWashington.
17
3/12/2012
Takayasu Disease=Pulseless
Disease=Pulseless Disease
ThereforewhenyouhaveTakayasuDisease,I
cantTakayupulse.
t T k l
FromDaleAlversonMD,Neonatologistatthe
UniversityofNewMexico 2011.
Hand&FingerAidforCyanoticHeart
Disease
Thumb one fortruncusarteriosus.
Twocrossedfingersfortranspositionofthegreat
T d fi f t iti f th t
arteries
Threefingersfortricuspidatresia.
FourfingersfortetralogyofFallot.
Fivefingerswigglingalongaroundfortotal
anomalouspulmonaryvenousreturn.
Multiplecontributors thefirstwasAnnKellamsMD,
GeneralPediatrician,UniversityofVirginia.
18
3/12/2012
SecretofSuccess
Itsnotyouraptitudebutyourattitudethat
d t
determinesyouraltitude.
i ltit d
RobertFiserMD,again.
Psychological/PsychiatricTherapy
Psychological/PsychiatricTherapy
HowtoExplainaTouchySubject
Ivemetafewpeoplewhoneededtherapy,butfar
more that could benefit from therapy
morethatcouldbenefitfromtherapy.
Youdontneed therapy(yourenotcrazy).
Youcouldbenefit fromtherapy(atrainedempathetic
listenertohelpyousortthroughyourproblems).
Makessomepatientsopentotherapywhootherwise
wouldnotbe.
ld b
FromChristopherFunesMD,OurLadyoftheLake
PediatricResidency,BatonRouge,LA 2011.(Most
beautifulresidencynameever.)
archildrens.org arpediatrics.org uams.edu
19
3/12/2012
HematuriaDifferential
HematuriaDifferential ABCDEFGKIJK
Anatomic:cysts/tumors Glomerulonephritis
Bl dd
Bladder:cystitis
titi Heme:bleeding
H bl di
Cancer:Wilmstumor diathesisorSSdisease
Drug:cyclophosphamide Infection:UTI
Exerciseinduced InJury
Factitious:Munchausen Kidneystonesor
hypercalciuria
ChronicCoughinInfants
ChronicCoughinInfants CRADLE
Cysticfibrosis Dyskineticcilia
Respiratoryinfections
R i t i f ti Lung,airway,and
L i d
pertussis,rings,slings, vascularmalformations,
andairwaythings larygnotracheomalacia,
Aspiration TEfistula, vocalcorddysfunction
GEreflux,swallowing Edema CHF.
disorder
20
3/12/2012
FineMotorDevelopmentandthe
Alphabet
Childrenlearntocopygeometricpatternsin
alphabeticalorder.
l h b ti l d
Circle,Cross,Square,Triangle,andDiamond
untilyougettothediamond,whichis
obviouslytwotriangles.
FromJudithAnnTheriot,MD
From Judith Ann Theriot MD Directorofthe
Director of the
GeneralPediatricClinicalResearchUnit,
UniversityofLouisville 2011.
ADDandTick
ADDandTickAssociatedInfectionsin
theSEareaoftheUSA
AllchildrenwithTickAssociatedInfectionsin
th SE
theSEareaoftheUnitedStatessufferfrom
f th U it d St t ff f
ADD AcuteDoxycyclineDeficiency.
FromRichardJacobsMD,Chairofthe
DepartmentofPediatrics,ArkansasChildrens
Hospital
p 2011.
21
3/12/2012
ArgyllRobinsonPupilofSyphiliticLues
Argyll RobinsonPupilofSyphiliticLues
LikeaLadyoftheNight accomodatingbut
notresponsive.
t i
Doyourememberwhataccomodationis?
Pupillaryconstrictionwhenfocusingonanear
object.Thesepupilsconstrictwith
accomodation but not in response to light
accomodationbutnotinresponsetolight.
StanfordShulmanMD,PediatricInfectious
Disease,NorthwestUniversity,Chicago,2011.
Definitionofa2yearold
Apsychoticdwarfwithagoodprognosis.
FromLenoreParksMD,GeneralPediatrician,
WakeForestUniversitySchoolofMedicine
2011.
22
3/12/2012
NAVELforFemoralAnatomy
Fromlateraltomedial:nerve,artery,vein,
emptyspace,lymphatics.
t l h ti
FromJimMarcinMD,PediatricIntensivist,
UniversityofCaliforniaatDavisinSacramento,
2011.
EstablishingRapportwithanAngry
Teenager
Askthemwhoseideaitwastocometoclinic.
A k
Acknowledgetheydonotwanttobethere.
l d th d t t t b th
Tellthemyoullgetthemoutasquicklyaspossible.
Askthemhowtheyseetheirparentsconcerns.
FromGeneShatzMD,AdolescentMedicine,Helen
DeVosChildrensHospitalinGrandRapids,MI
2011.
23
3/12/2012
DiGeorge SyndromeandCATCH
SyndromeandCATCH22
Congenitalheart(Rightsidedarch,conotruncal
defect ASD VSD)
defect,ASD,VSD)
Abnormalfacies
Thymicabsence
Cleftpalate
Hypocalcemia
Deletionat22q
FromAnnieChurchMD,ChiefofGeneralPediatrics,
UniversityofTennesseeatChattanooga 2011.
MUDPILESandIncreasedAnionGAP
Acidosis
Methanol Lacticacidosis
U
Uremia i Ethanolandethylene
Eth l d th l
Diabeticketoacidosis glycol
Paraldehydeand Salicyclates
propyleneglycol
Iron,isoniazid,
infection,inbornerrors
ofmetabolism
Annie Church again, the first of many with this response.
24
3/12/2012
FivePApproachtoFTT
Peeing chronicUTI,RTA,renaldamage.
Pooping CF,Hirschsprung,malabsorption.
Pumping CHF.
Pituitary cortisol,growthhormone
deficiency,hyperorhypothyroidism.
Parenting easilythebiggestcategory.
FromGregTrowbridge,GeneralPediatrician,
HelenDeVosChildrensHospital 2011.
NAACPsofEosinophilia
NAACPsofEosinophilia
Neoplasm
Allergy
Asthma
CortisolDeficiency
Parasites
FromGregTrowbridge,again.
25
3/12/2012
HowtoDecideifaPatientisReadyfor
Discharge
Ivealwaysfeltthatifyouwentintoa
h it l d ll d fi
hospitalandyelledfire,anyonewhocould
h ld
getupandleaveprobablydidntneedtobe
there.
Workswellevenonthoselessthan12months
oldifyouimaginetheycanwalk.
y g y
FromTomEdTownsend,MD,General
PediatricianandArkansasSeniorPediatrician
1978.
archildrens.org arpediatrics.org uams.edu
TheSecretofLife
Twotwins onealwaysoptimisticandhappy,
th th
theotheralwayspessimisticandsad.
l i i ti d d
RequiresmorethanIcanputonaslide,so
allowmetotellyouthestory.
FromTomEdTownsend,MD,General
Pediatrician and ArkansasSeniorPediatrician
PediatricianandArkansas Senior Pediatrician
themid1980s.
26