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Культура Документы
Pak Rudi berusia 60 tahun datang ke dokter dengan gejala cepat lelah, nafsu makan
berkurang, berkurangnya kandungan urin saat buang air kecil, otot kejang dan berkedut, dan
mengalami bengkak pada kaki mengidap gagal ginjal kronis. Ia berkonsultasi dengan dokter nya
tentang tindakan yang lebih baik untuk dilakukan kepada dirinya. Dokter menyarankan agar Pak
Rudi melakukan hemodialysis, sedangkan ia mendapatkan saran dari temannya untuk melakukan
transplantasi ginjal saja.
BACKGROUND QUESTION
FOREGROUND QUESTION
"Apakah transplantasi ginjal lebih efektif daripada hemodialysis untuk menangani gagal ginjal pak
Rudi?"
UNSUR PICO
TYPE OF QUESTION
Treatment/therapy
TYPE OF STUDY
Meta-analysis
KATA KUNCI
PEMILIHAN SITUS
http://www.ncbi.nlm.nih.gov/pubmed
HASIL PENCARIAN
Wyld, M., Morton, L.S., Hayen, A., Howard, K., Webster, A.C. (2012) A systematic review and
meta-analysis of utility-based quality of life in chronic kidney disease treatments. PLOS Medicine
9: 1-9.
ABSTRACT
BACKGROUND:
Chronic kidney disease (CKD) is a common and costly condition to treat. Economic evaluations of
health care often incorporate patient preferences for health outcomes using utilities. The objective
of this study was to determine pooled utility-based quality of life (the numerical value attached to
the strength of an individual's preference for a specific health outcome) by CKD treatment modality.
CONCLUSIONS:
For patients with late-stage CKD, treatment with dialysisis associated with a significant decrement
in quality of life compared to treatment with kidney transplantation. These findings provide
evidence-based utility estimates to inform economic evaluations of kidney therapies, useful for
policy makers and in individual treatment discussions with CKD patients.