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Group 5
Tutor :
dr. H. Achmad Azhari, DAHK
Members:
1. Armiko Bantara (702013010)
2. Istiqomah Maximiliani (702014057)
3. Aisyah Azani (702014066)
4. Dwi Puspita Sari (702014001)
5. Ardiansyah Wijaya (702014080)
6. Vonny Alfanda (702014085)
7. Viena Aprilia (702014029)
8. Tharisa Kurnia (702014043)
9. Muhammad Aiman (702014017)
10. Ghinafahriyah Delihefian (702014073)
11. Ahmad Reyhan (702014063)
MEDICAL FACULTY
MUHAMMADIYAH PALEMBANG UNIVERSITY
2017
PREFACE
Thanks to Allah SWT for helping and give us chance to finish this
Scenario B tutorial report on the 21st blok timely. Shalawat and salam always be
with our prophet Muhammad SAW and his family, friends, and followers until the
end of time.
We recognize that this tutorial report is far from perfect. Therefore we
expect constructive criticism and suggestions, in order to refine the next tasks.
In completing this tutorial task, we got a lot of help, guidance and advice.
On this occasion we would like to express our respect and gratitude to:
1. dr. Achmad Azhari, DAHK, as a tutor of group 5
2. All of the members who involved in the making of this report
May Allah SWT give a reward for all the charity given to all those who
have supported us and hopefully this tutorial report, useful for us and the
development of science. May we always be in the protection of Allah SWT.
Amen.
Author
i
TABLE OF CONTENT
PREFACE ................................................................................................................. 1
TABLE OF CONTENT ............................................................................................ 2
CHAPTER I INTRODUCTION
1.1 Issue Background .......................................................................................... 3
1.2 Purpose and Objectives ................................................................................. 3
BAB II DISCUSSION
2.1 Tutorial Data ................................................................................................ 4
2.2 Case Scenario ............................................................................................... 4
2.3 Clarification of Terms .................................................................................. 6
2.4 Identification of Problem .............................................................................. 7
2.5 Analysis and Synthesis of Problem .............................................................. 9
2.6 Hypothesis .................................................................................................... 40
2.7 Conceptual Framework ................................................................................ 40
BIBLIOGRAPHY ...................................................................................................... 41
ii
CHAPTER I
INTRODUCTION
Growth and Development & Geriatric Block is the 21st Block in the
seventh semester of the Competency Based Curriculum System Doctor
Education Faculty of Medicine, Muhammadiyah Palembang University. One
of the learning strategies of Competency Based Curriculum system is Problem
Based Learning (PBL). Tutorial is the implementation of Problem Based
Learning (PBL) method. In the tutorial students are divided into small groups
and each group is guided by a tutor / lecturer as a facilitator to solve the
existing case. On this occasion a case study of scenario B is presented which
presents the case; Ana, 10 months old girl, visited the outpatient clini RSMP
with recurrent diarrhea with her mother. She suffered from diarrhea almost
once a month since she was 4 months old. The length of diarrhea was 7 to 10
days. Her mother said that her daughters appetite was like usual. Ana is not
having fever, cough, cold and hard to breathe now.
Anas weight was never weighed (she was never taken to Public Health
Center). Highest weight was unknown. Ana was given exclusive breastfeeding
just until 3 months of age. Since her age was 3 months, she was given only
regular formula milk 6 times a day @90 cc until now. After her age was 4
months. She was given instant porridge as a complementary feeding (MP ASI)
2 times a dat @1/2 sachet (1 sachet is 80 kcal). She also was given cooked
rice (tajin) 2-3 times a day @50 cc since her age was 4 months.
3
CHAPTER II
DISCUSSION
4
months. She was given instant porridge as a complementary feeding (MP ASI)
2 times a dat @1/2 sachet (1 sachet is 80 kcal). She also was given cooked
rice (tajin) 2-3 times a day @50 cc since her age was 4 months.
Immunization History: BCG 1 time but DPT, polio, hepatitis dan measles
vaccines were never given.
Growth history: image attachment of ANAs KMS
Development history: Ana can only sit with help
Medication history: Ana was never got treatment
Physical examination:
General status: the child is not looking thin, round cheeks, pale, apathetic,
whiny, weight 5.5 kg, length 60 cm, head circumference 43 cm, upper arm
circumference 12 cm.
Vital Sign: HR 112x/minute, RR: 32x/minute, T: 36,5C
Spesific Status:
Head:
- No dismorphic face
- Round cheeks
- Easy revoked sheer yellowish red head hair
- Wistfull eyes
- Look and cry at the examiner
- Look towards when her name was called
Thorax: no ribs (piano sign)
Abdomen: bloated
Extremities:
5
- Edema in the four extremities
- No anatomy abnormalities to both legs and feet
- No baggy pants
Skin: there is skin skin abnormalities (dermatosis) in the buttocks and groin
Neurologicus status:
- normal movements, motoric muscle strenght 4
- Normal physiological reflexes
- Normal clonus and tone
- No uncontrollable movements
- No pathological reflexes
6
thoraco-clavicula ligament
7. Dismorphic face One or more aspect of the persons face are
abnormal in some way
8. Yellowish Red head The hair is hipopigmented vary in color from
hair a reddish yellow to gray or even white
9. Baggy Pants Skin disorders where the patient looks like
wearing loose pants due to loss of fat reserves
under the skin
10. Dermatosis A noninflammatory skin disorder
7
weight was 2800 grams. Birth length was 49 cm. Head circumference
was 33 cm.
7. Immunization History: BCG 1 time but DPT, polio, hepatitis dan
measles vaccines were never given.
8. Growth history: image attachment of ANAs KMS
9. Development history: Ana can only sit with help
10. Medication history: Ana was never got treatment
11. Physical examination:
General status: the child is not looking thin, round cheeks, pale,
apathetic, whiny, weight 5.5 kg, length 60 cm, head circumference 43
cm, upper arm circumference 12 cm.
Vital Sign: HR 112x/minute, RR: 32x/minute, T: 36,5C
12. Spesific Status:
Head:
- No dismorphic face
- Round cheeks
- Easy revoked sheer yellowish red head hair
- Wistfull eyes
- Look and cry at the examiner
- Look towards when her name was called
Thorax: no ribs (piano sign)
Abdomen: bloated
Extremities:
- Edema in the four extremities
- No anatomy abnormalities to both legs and feet
- No baggy pants
Skin: there is skin skin abnormalities (dermatosis) in the buttocks and
groin
13. Neurologicus status:
- Normal movements, motoric muscle strenght 4
- Normal physiological reflexes
- Normal clonus and tone
8
- No uncontrollable movements
- No pathological reflexes
9
c. Malabsorption (Deficiency of Disaccharides)
d. Endocrinopathy (Tiroxicosis, Addison's disease)
e. Neoplasm
f. Other causes (milk allergy, chron disease, immune
deficiency, water laxative)
Sumber:
(Subagyo dan Santoso, 2012)
10
b. What is the determinology of diarrhea almost once a month since
she was 4 months old and the lengsht of diarrhea was 7 to 10 days?
Answer:
Ana has a chronic diarrhea.
Based on the duration, diarrhea are divided into:
1) Acute diarrhea
Acute diarrhea is a bowel movement with increasing
frequency and consistency of soft or fluid stools and is suddenly
coming and lasting in less than 2 weeks.
2) Persistent diarrhea
Persistent diarrhea is diarrhea lasting 15-30 days, is a
continuation of acute diarrhea or a transition between acute and
chronic diarrhea.
3) Chronic diarrhea
Chronic diarrhea is diarrhea that comes and goes, or lasts
long with non-infectious causes, such as gluten-sensitive disease
or decreased metabolic disorders. The duration of chronic
diarrhea is more than 30 days. According to (Suharyono, 2008),
chronic diarrhea is diarrhea that is chronic or persistent and lasts
more than 2 weeks.
Source:
Suharyono, 2008
c. What is the pathophisiology of recurrent diarrhea in this case?
Answer:
11
2. Her mother said that her daughters appetite was like usual. Ana is
not having fever, cough, cold and hard to breathe now.
a. What is the meaning of her daughters appetite was like usual?
Answer:
Her daughters appetite was like usual means that there is no
problems with her appetite. The problem may caused by other causes
such as the lack ammount of compsumption or the metabolism
disorder.
b. How is the correlation between appetite like usual with the
complaints?
Answer:
The complaints is not caused by her appetite.
c. What is the meaning of ana is not having fever, cough, cold and
hard to breathe now?
Answer:
The meaning is the diarrhea that happened to Ana is not caused
by infectious factors.
3. Anas weight was never weighed (she was never taken to Public
Health Center). Highest height was unknown.
a. What is the meaning of Anas weight was never weighed and her
height was unknown?
Answer:
Anas family is not a KADARZI family. Keluarga Sadar Gizi
(KADARZI) is a family that is able to recognize, prevent and
overcome the nutritional problems of each member. A family is
called KADARZI if it has a good nutritional behavior that is
characterized by at least:
1. Weigh the weight regularly.
2. Provide breast milk (breast milk) only to infants from birth to
age 6 months (exclusive breastfeeding).
3. Eat the variaton food
4. Using iodized salt.
12
5. Drink nutritional supplements (TTD, high doses of Vitamin A
capsules) as recommended.
Source:
(DEPKES, 2012)
b. How about normal weight and height in infant aged 10 months?
Answer:
Based on Z-score growth chart;
Age:10 months
a. Weight : 8,2 kg
b. Lenght : 71,5 cm
c. Head circumference : 44,4 cm
Based on NCHS;
13
c. How is the normal growth and development of a 10-months-old
baby?
Answer:
The normal growth and development of a 9-12 months baby;
1. Can stand alone without help
2. Can walk guided
3. Imitate sound
4. Repeat the sound he heard
5. Learn to declare one or two words
6. Understand simple command or prohibition
7. Show great interest in exploring the surroundings, eant to touch
anything and put things into his mounth
8. Participating and games
Some milestones of child development that must be know
(developmental milestone is the level of development that must be
achieved by a child at a certain age) :
child 9-10 month :
1. Pointing with the index finger
2. Holding objects with thumb and forefinger
3. crawl
4. sound dadadada
Source:
Soetjiningsih, 2012
Synthesis:
Age Rough Fine motor Personal- Language
motoric and adaptive Social
2 weeks Head shifted - Recognize Alert to the bell
to the right the face
ang left
2 months Shrugs on his Follow the Smile as a Cooing
stomach object past the response Looking for a sound
14
center line source using the eyes
4 months Raise hands Looking for See the Laughing and crying
stomach objects hand
not found Raking grasp
headlag if Start
pulled from playing
supine with toys
sleeping
position
6 months Sitting alone Move objects Can feed Babble
from hand to yourself
hand Holding
the bottle
9 months Start learing start pincer Can waved Say bye-bye and
to stand up grasp bye-bye Mama, but not
Can sit alone bring together 2 play pat-a- spesific
blocks cake Say 2 syllables
15
According to the Decree of the health minister of the Indonesia
Republic number: 747 / menkes / sk / vi / 2007 on operational
guidelines of nutritionally conscious families in Desa Siaga, the
recommendation to weigh baby weight are the following;
16
Colostrum, produced in low quantities in the first few days
postpartum, is rich in immunologic components such as secretory
IgA, lactoferrin, leukocytes, as well as developmental factors such as
epidermal growth factor. The macronutrient composition of human
milk varies within mothers and across lactation but is remarkably
conserved across populations despite variations in maternal
nutritional status. The macronutrient composition of mature, term
milk is estimated to be approximately 0.9 to 1.2 g/dL for protein, 3.2
to 3.6 g/dL for fat, and 6.7 to 7.8 g/dL for lactose (Ballard et al,
2013).
The most abundant proteins are casein, -lactalbumin,
lactoferrin, secretory immunoglobulin IgA, lysozyme, and serum
albumin.Non-protein nitrogen-containing compounds, including urea,
uric acid, creatine, creatinine, amino acids, and nucleotides,
comprise ~25% of human milk nitrogen. And many micronutrients
vary in human milk depending on maternal diet and body stores
including vitamins A, B1, B2, B6, B12, D, and iodine. Also, Human
milk contains numerous growth factors that have wide-ranging
effects on the intestinal tract, vasculature, nervous system, and
endocrine system (Ballard et al, 2013).
Human milk is a dynamic, multi-faceted fluid containing
nutrients and bioactive factors needed for infant health and
development. Its composition varies by stage of lactation and
between term and preterm infants. While many studies of human
milk composition have been conducted, components of human milk
are still being identified. Standardized, multi-population studies of
human milk composition are sorely needed to create a rigorous,
comprehensive reference inclusive of nutrients and bioactive factors.
Nevertheless, knowledge of human milk composition is increasing,
leading to greater understanding of the role of human milk in infant
health and development (Ballard et al, 2013).
17
Benefits:
1. Lactose
As an energy-producing source, as a major carbohydrate, it
increases the absorption of calcium in the body, stimulating the
growth of lactobacilli bifidus.
2. Protein
Has a function for the regulator and builder of the baby's body.
3. Fat
Serves as a major heat / energy hazard, decrease the risk of heart
disease at a young age.
4. Vitamin A
Vitamins are very useful for the development of infant vision.
5. Iron
Substances that help the formation of blood to prevent the baby
from less blood or anemia.
6. Taurine
Neotransmitters are good for brain development of children.
7. Lactoferrin
Inhibits the development of candida and bacterial
staphylococcal fungi that harm the health of the baby.
8. Lisozyme
18
Very useful to reduce dentis caries and malocclusion and can
break down the walls of harmful bacteria.
9. Colostrum
10. Important substances that contain many nutrients and substances
of the baby's body from disease attack.
11. AA and DHA
Substances obtained from changes in omega-3 and omega-6 that
work for fetal and infant brain development.
19
from sudden infant death syndrome (SIDS). In a 2009 German
study, exclusive breastfeeding at one month of age halved the
risk of SIDS, and partial breastfeeding at one month of age also
reduced the risk. Being exclusively breastfed in the last month
of life fur- ther reduced the risk of SIDS, as did being partially
breastfed
c. Mortality
Not breastfeeding significantly increases a childs risk of
dying in infancy. In both developed and developing countries,
breastfeed- ing and human milk protects against post-neonatal
death.In developing countries infants who are not breastfed
have higher rates of diarrhea and respiratory diseases, both of
which are main causes of infant death. A cohort case study in
Ghana found a marked dose response of increasing risk of
neonatal mortality with increasing delay in initiation of
breastfeeding from 1 hourto day 7.
d. Weight
Not breastfeeding increases a childs risk of being both
overweight and obese. The estimated percentage of 6-11
year old U.S. chil- dren considered to be obese has more
than quadrupled to 19% since 1960. Infants who have never
been breastfed are at higher risk for later childhood obesity
than infants who have ever been breastfed.
e. Temperature and Respiratory Regulation
Bottle feeding puts an infant at risk for physiological
instabil-ity. Oxygen saturation and body temperature
were found to be significantly lower in preterm infants who
were bottle fed versus those who were directly breastfed.
f. Necrotizing Enterocolitis
Not breastfeeding significantly increases an infants risk of
nec- rotizing enterocolitis (NEC). NEC occurs in 3-10% of
20
VLBW infants and rarely in compromised term infants. It is
associated with an increased morbidity and mortality,
including growth and neurodevelopmental impairment,
infection and increased need for central line placement.
g. Pain
Not breastfeeding increases the infants response to pain.
An analysis of eleven studies demonstrates that both
breastfeeding and human milk are pain relieving. Neonates
who were swaddled or received a pacifier exhibited more
crying times (proportion and duration) and increased heart
rates when compared to breastfeed- ing infants. Pain scores
were significantly worse (more pain) for infants who were
not breastfeeding.
21
e. What are the effects of the infant was given formula milk?
Answer:
We must restrict the formula milk feeding because it will bring
the Jellife triage that are diarrhea due to infection, moniliasis in the
mouth and marasmus. The situation is caused because the bottle is
less hygiene cleaned up, bottle milk tends to dilute, thus reducing the
nutritional value.
5. After her age was 4 months. She was given instant porridge as a
complementary feeding (MP ASI) 2 times a dat @1/2 sachet (1 sachet
is 80 kcal). She also was given cooked rice (tajin) 2-3 times a day @50
cc since her age was 4 months.
a. What is the meaning of she was given instant porridge as a
complementary feeding when she was 4 months?
Answer:
It means that breastfeeding was not given exclusively.
b. How to feed children by age?
Answer:
Pattern of giving the breast milk and complementary feeding;
22
Example of Daily Menu;
23
c. How is the caloric needs based on age?
Answer:
Ideal weight: 8,5 kg
Caloric Needs:
Ideal Weight x RDA cased on height age= caloric needs
8,5x 100 =850 kkal
24
Cooked rice water composition
It contains 7-10% protein, low calcium, glucose and other minerals.
(Silvia, 2010)
25
b. How to assess APGAR Score on newborns?
Answer:
Interpretation:
7-10 = Normal
4-6 = Mild
0-3 = Severe
26
IDAI, 2017
8. Growth history: image attachment of ANAs KMS
27
a. How is the interpretation of growth history?
Answer:
At the age of 0-2 months the growth rate pattern follows the
normal growth curve (SD 0), on month 3 to month 9 growth rate
Can only sit but with the help rough motoric development
disorder
10. Medication history: Ana was never got treatment
a. How is the interpretation of medication hisory?
Answer:
Anas parent never take ana to take a treatment may caused by many
factors; knowledge factor, socioeconomic factor and caring factor.
11. Physical Examination
General status: the child is not looking thin, round cheeks, pale,
apathetic, whiny, weight 5.5 kg, length 60 cm, head circumference 43
cm, upper arm circumference 12 cm.
Vital Sign: HR 112x/minute, RR: 32x/minute, T: 36,5C
a. How is the interpretation of physical examination?
Answer:
Physical Examination Normal Interpretation
Not looking thin Not looking thin Normal
Round Cheeks Abnormal, Edema
Pale Abnormal
Apatis Compos mentis Loss of
28
consciousness
Whiny Not Whiny Abnormal, more
often in
malnourished
children
Weight 5,5 kg 8,5 kg >-3 SD
Malnutrition
under percentil -
3
Length 71 cm Failed to grow
Head Circumference 45-48 cm Normal
45 cm
HR 112 x/menit 120-160 Normal
x/menit
RR 32 x/menit 20-60 x/menit Normal
37,50C 36,5-37,2oC Normal
29
12. Spesific Status
Head:
- No dismorphic face
- Round cheeks
- Easy revoked sheer yellowish red head hair
- Wistfull eyes
- Look and cry at the examiner
- Look towards when her name was called
Thorax: no ribs (piano sign)
Abdomen: bloated
Extremities:
- Edema in the four extremities
- No anatomy abnormalities to both legs and feet
- No baggy pants
Skin: there is skin skin abnormalities (dermatosis) in the buttocks and
groin
a. How is the interpretation of spesific status?
Answer:
Spesific Status Normal Interpretation
Round cheeks, easy recoked Tidak ada Clinic manifestation i
sheer yellowish red head hair, Kwashiokor patient
wistfull eyes, look and cry at the
examiner, abdomen bloated,
edema in four extremities and
dermatosis in the buttocks and
groin
No ribs (piano sign), no baggy Tidak ada edema Normal, Usually in marasmus
pants
30
b. How is the abnormal mechanism of spesific status?
Answer:
31
- Normal clonus and tone: normal
- No uncontrollable movements: normal
- No pathological reflexes: normal
32
15. How is the differential diagnosis in this case?
Answer:
Marasmus-
Gejala Kasus Kwashiorkor Marasmus
kwashiorkor
Tampak kurus + - + -
Rambut tipis mudah
+ + + +
di lepas
Infeksi berulang + + + +
Iga gambang
+ - + +
Dan edema
Abdomen cekung + - + -
Baggy pants + - + -
Penurunan BB + + + -
33
18. What treatment should be given in this case?
Answer:
Treatment:
34
b. antibiotics (see step 5)
c. two-hourly feeds, day and night (see step 7)
If the child is unconscious, lethargic or convulsing give:
a. IV sterile 10% glucose (5ml/kg), followed by 50ml of 10%
glucose or sucrose by Ng tube. Then give starter F-75 as
above
b. antibiotics
c. two-hourly feeds, day and night
Monitor:
35
3. Step 3: Treatment/ Prevent dehydration
Treatment:
It is difficult to estimate dehydration status in a severely malnourished
child using clinical signs alone. So assume all children with watery
diarrhoea may have dehydration and give:
a. ReSoMal 5 ml/kg every 30 min. for two hours, orally or by
nasogastric tube, then
b. 5-10 ml/kg/h for next 4-10 hours: the exact amount to be given
should be determined by how much the child wants, and stool
loss and vomiting. Replace the ReSoMal doses at 4, 6, 8 and 10
hours with F-75 if rehydration is continuing at these times, then
c. continue feeding starter F-75 (see step 7) During treatment,
rapid respiration and pulse rates should slow down and the child
should begin to pass urine.
36
6. Step 6: Correct micronutrient deficiencies
Give:
Vitamin A orally on Day 1 (for age >12 months, give 200,000 IU; for
age 6-12 months, give 100,000 IU; for age 0-5 months, give 50,000
IU) unless there is definite evidence that a dose has been given in the
last month
a. Multivitamin supplement
b. Folic acid 1 mg/d (give 5 mg on Day 1)
c. Zinc 2 mg/kg/d
d. Copper 0.3 mg/kg/d
e. Iron 3 mg/kg/d but only when gaining weight
7. Step 7: Start caution feeding
The essential features of feeding in the stabilisation phase are:
a. small, frequent feeds of low osmolarity and low lactose
b. oral or nasogastric (NG) feeds (never parenteral preparations)
c. 100 kcal/kg/d
d. 1-1.5 g protein/kg/d
e. 130 ml/kg/d of fluid (100 ml/kg/d if the child has severe oedema)
f. if the child is breastfed, encourage to continue breastfeeding but
give the prescribed amounts of starter formula to make sure the
childs needs are met.
8. Step 8: Achieve catch-up growth
9. Step 9 : Provide sensory stimulation and emotional support
severe malnutrition there is delayed mental and behavioural
development.
Provide:
a. tender loving care
b. a cheerful, stimulating environment
37
c. structured play therapy 15-30 min/d (Appendix 10 provides
examples)
d. physical activity as soon as the child is well enough
e. maternal involvement when possible (e.g. comforting, feeding,
bathing, play)
10. Step 10: Prepare for follow-up after recovery
Good feeding practices and sensory stimulation should be continued at
home. Show parent or carer how to:
a. feed frequently with energy- and nutrient-dense foods
b. give structured play therapy
Advise parent or carer to:
a. bring child back for regular follow-up checks
b. ensure booster immunizations are given
c. ensure vitamin A is given every six months
38
Refeeding syndrome is one of the metabolic complications of
nutritional support in severe malnourished patients characterized by
hypophosphatemia, hypokalemia, and hypomagnesemia. This occurs as a
result of changes in the main energy source of the body's metabolism,
from fat at the time of starvation to carbonhydrate given as part of
nutritional support, resulting in an increase in insulin levels and the
electrolyte displacement required for intracellular metabolism. Clinically
patients may develop dysrhythmias, heart failure, acute respiratory
failure, coma paralysis, nephropathy, and liver dysfunction. Therefore, in
the provision of nutritional support in patients with severe malnutrition
needs to be given gradually
(Pudjiadi et al, 2010)
20. What is the medical doctor compentences in this case?
Answer:
4A
Ability level 4. Doctor graduates are able to make a clinical diagnosis
and manage the disease independently and thoroughly.
21. What is the prognosis in this case?
Answer:
Quo ad vitam: dubia ad bonam
Quo ad functionam: Dubia ad malam
22. NNI
Right to get breastfeeding exclusively
Al-Baqarah: 233
39
Mothers may breastfeed their children two complete years for
whoever wishes to complete the nursing [period]. Upon the
father is the mothers' provision and their clothing according to
what is acceptable. No person is charged with more than his
capacity. No mother should be harmed through her child, and no
father through his child. And upon the [father's] heir is [a duty]
like that [of the father]. And if they both desire weaning through
mutual consent from both of them and consultation, there is no
blame upon either of them. And if you wish to have your children
nursed by a substitute, there is no blame upon you as long as you
give payment according to what is acceptable. And fear Allah and
know that Allah is Seeing of what you do.
2.6 Hypothesis
Ana, a 10 months old girl, experiencing malnutrition type kwashiokor+
failure to thrive et causa Breastfeeding is not given exclusively dan recurrent
diarrhea.
Lactosa intolerance
Recurrent diarrhea
Malnutrition (Kwashiokor)
failure to thrive
40
BIBLIOGRAPHY
Hidajat, Irawan dan Hidajati. Pedoman Diagnosis dan Terapi: Bag/SMF Ilmu
Kesehatan Anak. Surabaya: RSU dr. Soetomo.
Lacorence RA. 1980. Breast feeding, a guide for the medical proffesion.
USA:Mosby
Silvia. 2010. Penetapan Kadar Kalsium pada Susu Sapi, Susu Sapi Kemasan dan
Air Tajin secara Spektrofotometri Serapan Atom. Medan: Universitas
Sumatera Utara (Naskah Publikasi)
Subagyo, B., Santoso, N.B. 2012. Diare Akut, Buku Ajar Gastroenterologi-
41
Hepatologi. Ikatan Dokter Anak Indonesia.
Suharyono. 2008. Diare Akut, Klinik dan Laboratorik. Jakarta: Rineka Cipta
Spatz, D.L dan Lessen R. 2011. Risk of not Breastfeeding. International Lactation
Consultant Association
42