Академический Документы
Профессиональный Документы
Культура Документы
Follicular phase
1
Follicular phase
2
Ovulation
Wall of Graffian follicle ruptures
Antral fluid with oocyte flows to ovarian
surface
Fluid and oocyte released
Oocyte enters uterine tube
Hormonal control: LH surge is trigger
3
Ovarian cycle: summary
Uterine Cycle
Reflects hormonal changes during ovarian cycle
Averages 28 days
Consists of three phases
Menstrual phase (decreased oestrogen & progesterone)
Uterine lining is shed. 5-7 days
Proliferative phase (oestrogen)
Endometrium renewed in preparation for possible pregnancy
Secretory or progestational phase (progesterone)
Coincides with luteal phase. Endometrium develops
4
Menstrual phase
Characterized by discharge of blood and endometrial
debris from vagina
First day of menstruation is considered start of new cycle
Coincides with end of ovarian luteal phase and onset of
follicular phase
Triggered by decreased oestrogen and progesterone:
hormones decrease when CL degenerates
Release of uterine prostaglandin
Causes vasoconstriction of endometrial vessels
Disrupts blood supply
Causes death of endometrium
Stimulates mild rhythmic contractions of uterine
myometrium
Helps expel the menstrual flow
Proliferative phase
Begins concurrent with last portion of ovarian follicular phase
5
Secretory phase
Endometrium prepared for implantation
Blood supply increased
Glands enlarge and secrete glycogen-rich fluids
Secretory phase conditions promoted by progesterone
6
Hormonal control of the cycle
GnRH
Gonadotropins (FSH and LH)
Oestrogen and progesterone
7
Oestrogen secreted first
from the follicle, then from
the corpus luteum
Progesterone secreted
from the corpus luteum
LH and FSH secreted from
the anterior pituitary
Oestrogen and
progesterone inhibit LH and
FSH secretion
8
Regulation of Hormone Secretion
Late Follicular Phase
Oestrogens stimulate LH
secretion (opposite of usual
effect)
9
Regulation of Hormone Secretion: Luteal
Phase
10