Based on studies of somatization disorder, medication approaches rarely are successful for this condition.

Physicians should search for

evidence of psychiatric comorbidity, such as depression or an anxiety disorder. If present, medication interventions specific to the diagnosis can
be attempted. Successful treatment of a major depression or an anxiety disorder, such as panic disorder, also may produce significant reduction
in somatization disorder.
There are no medications approved specifically for the treatment of hypochondriasis, somatic symptom disorder, or illness anxiety
disorder. Medications are usually started to treat the comorbid depression or anxiety disorder.
A recent clinical trial in China found a combination of the serotonin reuptake inhibitors (SSRI) citalopram with the atypical
antidepressant paliperidone to be more effective than citalopram alone for the treatment of a group of mixed group of somatoform disorder
subjects.

Antidepresan
Imipramine is a tricyclic antidepressant that has demonstrated clear superiority over the placebo in double-blind trials for treating specific
symptoms of bulimia nervosa. However, SSRIs (eg, fluoxetine) probably should be first-line agents.
SSRIs are greatly preferred over the other classes of antidepressants. Because the adverse effect profile of SSRIs is less prominent,
improved compliance is promoted. SSRIs do not have the cardiac arrhythmia risk associated with tricyclic antidepressants. Arrhythmia risk is
especially pertinent in overdose, and suicide risk must always be considered when treating a child or adolescent with mood disorder.
Sumber: http://emedicine.medscape.com/article/294908-medication#2

Dd gangguan somatoform
Undiagnosed Medical Illness
Psychotic Disorder
 Psychological Factors Affecting Medical Illness
Factitious
Malingering
Keluhan fisik atau cemas irasional
tentang sakit atau penampilan

Keluhan fisik dapat dijelaskan PENYAKIT UMUM Faktor psikologik YA FAKTOR PSIKOLOGIK
YA
dengan penyakit umum dan Spesifik (bukan gangguan memperburuk penyakit MEMPENGARUHI
keluhan tidak lebih dari yang somatoform) umum PENYAKIT UMUM
diarapkan

TIDAK
YA
Gejala fisik sengaja Tidak ada insentif dari GANGGUAN
dibuat luar BUATAN

TIDAK TIDAK
BERPURA-PURA

Riwayat Keluhan fisik berulang dengan YA

sedikitnya 4 gejala nyeri, 2 gejala GANGGUAN SOMATISASI
gastrointestinal , 1 gejala seksual dan 1
gejala pseudoneurologik

TIDAK

Gejala atau defisit YA

mempengaruhi fungsi motorik GANGGUAN KONVERSI

atau sensorik

TIDAK
 YA
Gejala atau defisit
DISFUNGSI SEKSUAL
mempengaruhi fungsi seksual

TIDAK

YA
Nyeri merupakan keluhan GANGGUAN NYERI
utama, dan faktor psikologik SOMATOFORM
berperanan penting
TIDAK
YA
Keluhan fisik lain sedikitnya GANGGUAN SOMATOFORM
berlangsung selama 6 bulan TAK TERINCI

TIDAK

YA TIDAK
Preokupasi dengan gagasan Kepercayaan
HIPOKONDRIASIS
sakit serius seperti Waham

YA
TIDAK

Lihat silsilah
gangguan psikotik
YA
Preokupasi dengan kelainan GANGGUAN DISMORFIK
penampilan TUBUH (jika taraf waham juga
lihat silsilah gangguan psikotik)
TIDAK

Gejala somatoform yang YA

bermakna secara klinis yang GANGGUAN SOMATOFORM
tidak memenuhi kriteria YTT
Gangguan somatoform sesifik

TIDAK

Bukan Gangguan Somatoform

(Gejala somatoform yang tidak
bermakna secara klinis)