Академический Документы
Профессиональный Документы
Культура Документы
369-1-3022 Invertebrates
Diversity and classification of invertebrates, body plane, physiology, locomotion, reproduction, nutrition,
defense mechanisms and sensory organs, symbiosis, biomechanics and calcification, architecture and
function, the kingdom of extreme environments terrestrial and aquatic strategies, biotechnological
applications.
369-1-3023 Vertebrates
Characterization of the chordata, phylogenesis and classes of the vertebrata, breathing, transport
systems, excretion and reproduction systems, embryonic development, skeletal structure and function,
sensory organs.
369-1-4081 Bioreactors
Heat and mass balances. Batch and continuously stirred reactors. Residence time distribution.
Biotechnological processes. Kinetics of microbial growth. Product and medium utilization. Transfer
phenomena in microbial systems. Non-Newtonian flow. Desgin and analysis of biological reactors.
Analysis of complex microbial populations. Stability f bioreactor operation with complex population.
369-1-4141 Bioinformatics
Genome sequence analysis (homology searching, scoring matrices, sequence alignment, genome
mapping and assembly). Functional genomics : array technology & uses (gene discovery, disease
diagnosis, drug discovery, toxicological research); data analysis (error analysis, clustering-PCA,
decision trees, correlations, SOM). Gene networks- logic based models, qualitative methods quantitative
methods. Metabolic pathways- measurements and analysis. The genomics and proteomics projects,
data basis on the web.
369-1-6041 Bioelectronics
This course is an introduction to some newer fields in biotechnology, namely biosensors, biochips and
nanobiotechnology. Biosensors include a study on biospecific entities, transducers (optical fibers
(chemiluminescent, fluorescent and bioluminescent), piezoelectric crystals, micro- and ultra-electrodes),
chemical immobilization of sensor surfaces and their analysis. Examples studied will be
immunosensors, whole-cell bioreporter sensors, amperometric enzyme biosensing and mass acoustic
sensing. Micro-array and biochip technologies will be studied in the context of gene discovery,
bioinformatics, proteomics and drug discovery. Nanobiotechnology, will include atomic force
microscopy, DNA-scaffolds, polymer nano-electronics and nano-colloids.
369-2-6611 Biosensors
Definitions, history and market needs. Target analytes. Sensors based on: enzymes, affinity and whole-
cells. Transducers: electrodes, photometric and acoustic. Immobilizations techniques: thin films, micro &
nano-structures. Invasive, non- invasive, and disjointed sensors . Continuous vs. discontinuous
monitoring . Pitfalls. Quality control. Signal processing. Case studies: immunosensors. Novel
transducers and synthetic receptors. Clinical, environmental, industrial and military applications. Future
prospects. Patents issues. Commercialization. (create your own biosensor).
369-2-6621 Nanobiotechnology
Nano-biotechnology is the manipulation of matter at the molecular level to create new products with
atom by atom precision. This technological revolution will be described in the context of biotechnology.
The course will describe the principles of scanning probe microscopy: molecular resolution of bio/in-
organic materials, chemical imaging by scanning force microscopy, the quantification of adhesion forces
between molecules, positioning signal atoms using proximal probes and finally either destructive or
constructive molecular manipulations. We will elaborate on the problems and constraints of
nanobiotechnology and discuss how these effect the future of molecular lithography. Molecular sensors,
molecular manufacturing, biochips and bioelectronics.