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2.

EXTENDINGMENDELIANGENETICS
&MOLECULARGENETICS

Dr.FennyM.Dwivany

KULIAHGENETIKABIOLOGISITH2008
1.EXTENDINGMENDELIANGENETICS

TherelaAonshipbetweengenotypeand
phenotypeisrarelysimple
incompletedominance:heterozygousindividual
hasphenotypeintermediatebetweenthoseofthe
twotypesofhomozygotes(red,whitepink
ower)
Codominance:heterozygoteexhibitsphenotypes
forbothitsalleles

KULIAHBIOLOGIMOLEKULERSITH2006
Inincompletedominance
ThephenotypeofF1hybridsissomewherebetweenthe
phenotypesofthetwoparentalvarieAes
PGeneraAon White
Red C WC W
CRCR

Gametes CR C W

Pink
F1GeneraAon CRCW

1
2 1
2 R
Gametes CR C

1
Eggs 2 CR 12 CR Sperm
F2GeneraAon
1
2 CR
CRCR CRCW
1
2 Cw
CRCW CWCW

KULIAHBIOLOGIMOLEKULERSITH2006
MulAplealleles
Pleiotropyistheabilityofsinglegenetoaect
mulAplephenotypictraitssicklecell
disease
Epistasis(greek:stoppingorcausingtostand):
onegeneaetcstheexp.Anothergene
colorfrommorethanonegene

KULIAHBIOLOGIMOLEKULERSITH2006
KULIAHBIOLOGIMOLEKULERSITH2006
Table14.2

KULIAHBIOLOGIMOLEKULERSITH2006
PolygenicInheritance
Formanycharacter(skincolor):character
varyinpopulaAon(ingradaAon)orcalled
quan.ta.vecharactersusuallyindicates
polygenicinheritance:anaddiAveeectof
twoormoregenesonsinglephenotypic
character
Eq:skincolor

KULIAHBIOLOGIMOLEKULERSITH2006
Theenvironmentalimpactthe
phenotype
Skincolor

KULIAHBIOLOGIMOLEKULERSITH2006

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