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EXTENDINGMENDELIANGENETICS
&MOLECULARGENETICS
Dr.FennyM.Dwivany
KULIAHGENETIKABIOLOGISITH2008
1.EXTENDINGMENDELIANGENETICS
TherelaAonshipbetweengenotypeand
phenotypeisrarelysimple
incompletedominance:heterozygousindividual
hasphenotypeintermediatebetweenthoseofthe
twotypesofhomozygotes(red,whitepink
ower)
Codominance:heterozygoteexhibitsphenotypes
forbothitsalleles
KULIAHBIOLOGIMOLEKULERSITH2006
Inincompletedominance
ThephenotypeofF1hybridsissomewherebetweenthe
phenotypesofthetwoparentalvarieAes
PGeneraAon White
Red C WC W
CRCR
Gametes CR C W
Pink
F1GeneraAon CRCW
1
2 1
2 R
Gametes CR C
1
Eggs 2 CR 12 CR Sperm
F2GeneraAon
1
2 CR
CRCR CRCW
1
2 Cw
CRCW CWCW
KULIAHBIOLOGIMOLEKULERSITH2006
MulAplealleles
Pleiotropyistheabilityofsinglegenetoaect
mulAplephenotypictraitssicklecell
disease
Epistasis(greek:stoppingorcausingtostand):
onegeneaetcstheexp.Anothergene
colorfrommorethanonegene
KULIAHBIOLOGIMOLEKULERSITH2006
KULIAHBIOLOGIMOLEKULERSITH2006
Table14.2
KULIAHBIOLOGIMOLEKULERSITH2006
PolygenicInheritance
Formanycharacter(skincolor):character
varyinpopulaAon(ingradaAon)orcalled
quan.ta.vecharactersusuallyindicates
polygenicinheritance:anaddiAveeectof
twoormoregenesonsinglephenotypic
character
Eq:skincolor
KULIAHBIOLOGIMOLEKULERSITH2006
Theenvironmentalimpactthe
phenotype
Skincolor
KULIAHBIOLOGIMOLEKULERSITH2006