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Clinical Gastroenterology and Hepatology 2014;12:636643

Prevalence, Trends, and Risk Factors for Fecal Incontinence


in United States Adults, 20052010
Ivo Ditah,* Pardha Devaki, Henry N. Luma, Chobufo Ditah, Basile Njei,k Charles Jaiyeoba,
Augustine Salami,# Calistus Ditah,** Oforbuike Ewelukwa, and Lawrence Szarka*,

*Department of Medicine, Division of Gastroenterology and Hepatology, and Clinical Enteric Neurosciences Translational and
Epidemiology Research Program, Mayo Clinic, Rochester, Minnesota; Department of Medicine, Wayne State University,
Detroit, Michigan; Department of Medicine, Hopital General Douala, Douala, Cameroon; kDepartment of Medicine, University
of Connecticut School of Medicine, Farmington, Connecticut; Department of Medicine, St Mary Mercy Hospital, Livonia,
Michigan; #Department of Medicine, Department of Gastroenterology, Henry Ford Hospital, Detroit, Michigan; **Department of
Medicine, University of Michigan Medical School, Ann Arbor, Michigan; and Department of Medicine, Wright University,
Dayton, Ohio

BACKGROUND & AIMS: We investigated the prevalence of and trends and risk factors for fecal incontinence (FI) in the
United States among non-institutionalized adults from 2005 to 2010.

METHODS: We analyzed data from 14,759 participants in the U.S. National Health and Nutrition Exami-
nation Survey (49% women, 20 years or older) from 2005 to 2010 (the FI Severity Index was
added in 20052006). FI was dened as accidental leakage of solid or liquid stool or mucus at
least once in preceding month. Sampling weights were used to obtain estimates for the national
population. Logistic regression was used to identify risk factors for FI.

RESULTS: The prevalence of FI among non-institutionalized U.S. adults was 8.39% (95% condence in-
terval, 7.769.05). It was stable throughout the study period: 8.26% in 20052006, 8.48% in
20072008, and 8.41% in 20092010. FI resulted in release of liquid stool in most cases
(6.16%). Prevalence increased with age from 2.91% among 20- to 29-year-old participants to
16.16% (14.15%18.39%) among participants 70 years and older. Independent risk factors for
FI included older age, diabetes mellitus, urinary incontinence, frequent and loose stools, and
multiple chronic illnesses. FI was more common among women only when they had urinary
incontinence.

CONCLUSIONS: FI is a common problem among non-institutionalized U.S. adults. Its prevalence remained stable
from 20052010. Diabetes mellitus and chronic diarrhea are modiable risk factors. Future
studies on risk factors for FI should assess for presence of urinary incontinence.

Keywords: NHANES; Fecal Incontinence; Prevalence; Trends; Risk Factors.

ecal incontinence (FI) is the recurrent, involuntary and women.1,2,5,9,12,13 Most patients with FI do not
F passage of fecal matter (solid, liquid, or mucus) or
the inability to control the discharge of bowel con-
report these symptoms to their care providers for fear
of embarrassment.2,14 In 2005, the Pelvic Floor
tents.13 It has socially devastating effects including poor Disorders Network submitted a validated FI severity
self-image, social isolation, and poor quality of life.4,5 It can scale for inclusion in the National Health and Nutrition
lead to depression, anxiety, and loss of employment.6,7 The Evaluation Survey (NHANES). The rst national
average total annual direct cost of FI in the United States is prevalence of FI was reported in 2009.3 These
estimated at $17,166 per person.6,7 It is one of the leading estimates were limited by small number of participants.
causes of referral to nursing homes.4,810 The prevalence
of FI in the United States is reported to range from 2.2%
to 24%, with most estimates ranging from 7% to
12%.2,3,8,11 This variation is largely due to differences in Abbreviations used in this paper: CI, condence interval; FI, fecal incon-
tinence; NHANES, National Health and Nutrition Evaluation Survey; UI,
the denition of FI, study populations, and survey urinary incontinence.
methods.1,2,9
2014 by the AGA Institute
A majority of the data on FI comes from specic 1542-3565/$36.00
subgroups of the population, notably referral population http://dx.doi.org/10.1016/j.cgh.2013.07.020
April 2014 Current Epidemiology of FI in the US 637

From a public health perspective, the burden of FI on lumpy), ratings 35 (normal consistencies), and ratings
individuals, families, and society cannot be under- 6 and 7 (mushy and watery).
estimated. FI is projected to become a major challenge as Table 1 summarizes denitions of the various factors
the proportion of the elderly increases in the general included in the study.
population. Age remains the most consistent risk factor for
FI.1,3,8,15 The prevalence of FI among U.S. adults rose from
Statistical Analysis
2.6% in 20- to 29-year-olds to 15.3% in adults 70 years
and older.3 Other factors including gender, race, urinary
All estimates and measures of association were
incontinence (UI), body mass index, and diabetes have
derived by using the sampling weights provided by the
been inconsistently associated with FI.2,3,1517 The study
National Center for Health Statistics. These weights
by Whitehead et al3 included only 4308 individuals. Our
consider unequal probabilities of selection resulting from
study involved 14,759 participants, making it the largest
sample design, nonresponse, and planned oversampling
ever population-based study on FI in the United States.
of the elderly, non-Hispanic black, and Mexican-American
Our study involved 3 NHANES cycles, allowing for the
populations.
assessment of FI trends.
The analysis was limited to adults 20 years and older.
To date, there are no data on the trends of FI in the
Individuals with missing questionnaire items or who
United States. We hypothesized that because of the
refused to answer the FI questions were excluded from
changing age distribution of the U.S. population, the
the analysis. Stata program (Stata Corporation, College
prevalence of FI is almost certainly on the increase. The
Station, TX) was used to calculate prevalence estimates
NHANES has collected and reported data on FI from
and their 95% condence intervals (CIs). The examina-
2005 through 2010. This represents the largest data set
tion sample weights adjust for unequal probabilities of
on FI and allows for calculation of robust estimates. The
selection and nonresponse and are post-stratied to
aims of this study were to (1) estimate the prevalence of
population control totals for each sampling subdomain.
FI, (2) analyze trends in FI, and (3) identify independent
Estimates with relative standard errors greater than
risk factors for FI among U.S. adults.
30% are identied as statistically unreliable. Prevalence
was stratied by age, gender, and stool type. Time trends
Methods are presented by age and gender. The results are shown
on bar charts and tables. First, age-adjusted bivariate
analyses were performed. Only factors that reached a
The NHANES program consists of annual cross-
signicance limit of 0.10 in this analysis were included in
sectional, national health surveys conducted by the
the multivariate analysis. The model was built in a for-
National Center for Health Statistics, Centers for Disease
ward manner by adding one variable at a time. Interac-
Control and Prevention. Demographic, socioeconomic,
tion between UI, gender, and age to explore for effect
and health interview data are collected in the home,
modication was also performed. The Pearson c2 test
followed by physical examinations, interviews, and lab-
with a signicance limit of 0.05 was used to identify risk
oratory assessments in mobile examination centers.
factors for FI.
The detailed procedural methods pertaining to data
on FI have been previously published.3 The NHANES
20052010 data were combined to provide the de-
nominator for this study. The bowel health question- Results
naire includes questions from the Fecal Incontinence
Severity Index,18 which asks about the frequency of Survey Response
accidental bowel leakage during the past month
separately for gas, mucus, liquid, and solid stool. Fre- Overall, 23,198 participants 20 years and older were
quency is assessed as 2 or more times a day, once a invited to participate in the NHANES household survey
day, 2 or more times a week, once a week, 13 times a during the 5-year period. Of these, 16,539 individuals
month, or never. For this study, FI was dened as any (71.3%) responded to the invitation and completed the
involuntary loss of mucus, liquid, or solid stool in the survey. Unfortunately, 1776 of the respondents (10.7%)
last 30 days. The bowel health questionnaire also did not complete the health examination components that
asked survey participants how often they usually have included the bowel health questionnaire. Four partici-
bowel movements. For data analysis, their responses pants (0.03%) specically refused to complete the FI
were merged into 3 ranges: <3/wk, 321/wk, and section of the questionnaire. For this study, only the
>21/wk. 14,759 participants who completed the FI questionnaire
The Bristol Stool Scale19 was used to determine have been included in the analysis. These participants
the participants usual stool consistency.20,21 For the were distributed as follows: 4308 (29.2%) in 20052006,
NHANES survey, participants were asked, What is 5 174 (35.1%) in 20072008, and 5277 (35.8%) in
your usual or most common stool type? For this 20092010. Supplementary Figure 1 shows owchart of
study, we pooled stool type ratings 1 and 2 (hard and survey invitees and response during each study cycle.
638 Ditah et al Clinical Gastroenterology and Hepatology Vol. 12, No. 4

Table 1. Denitions and/or Categorization of Operational Terms

Variable Denition/categories

Age Only individuals older than 20 years were eligible. Age was categorized as 2029 years, 3039 years, 4054 years,
5569 years, and 70 years and older.
Race On the basis of self-reported information, participants were classied into Mexican American and other Hispanic,
non-Hispanic white, non-Hispanic black, and other race/ethnicity groups.
Marital status It was classied as widowed, separated, or divorced; married or cohabitating with a partner; and never married.
Education level Education was dened as having less than a high school education, a high school diploma (including general
educational development [GED]), or additional education beyond high school.
Poverty Income was represented by the poverty income ratio (PIR), which varies by family size and composition (www.census.
index ratio gov/hhes/www/poverty/denitions.html#ratio). For this study, participants were classied as at or above the
poverty threshold vs below the threshold.
Body mass index The body mass index (BMI) was calculated as measured weight (kg)/height (m2); overweight was dened by a BMI
of 25.029.9 kg/m2, and obesity was dened by a BMI >30 kg/m2.
Physical activity Vigorous physical activity was dened as activity done for at least 10 minutes in the past 30 days that caused heavy
sweating or large increases in breathing or heart rate; moderate physical activity was dened as activity done for
at least 10 minutes that caused only light sweating or a slight to moderate increase in breathing or heart rate.
Pregnancy Pregnancy status was assessed by participant self-report and/or a urine pregnancy test.
Diabetes mellitus Diabetes mellitus was dened as a positive response to any of 3 questions: (1) Have you ever been told by a doctor
or other health professional that you have diabetes or sugar diabetes?, (2) Are you now taking insulin?,
and (3) Are you now taking diabetic pills to lower your blood sugar?
Chronic illnesses The presence of Chronic illnesses was ascertained by 13 separate questions on the form: Have you ever been told
by a doctor that you have arthritis, congestive heart failure, coronary heart disease, angina or angina pectoris,
heart attack, stroke, emphysema, chronic bronchitis, chronic liver condition, cancer or malignancy, asthma,
anemia, visual problems, or osteoarthritis? The cumulative number of positive responses to these 13 questions
was divided into 3 categories: 0 (none), 12, and 3 or more.
General health Self-described general health status was dened by the question Would you say that in general your health is
status excellent, very good, good, fair, or poor? Responses to this question were aggregated into 2 ranges: excellent,
very good, or good health status versus fair or poor health.
Urinary Urinary incontinence was assessed by using the Incontinence Severity Index,37,38 which consists of 2 questions:
incontinence How often do you have urinary leakage? Would you say never, less than once a month, a few times a month,
a few times a week, or every day and/or night (responses coded 15)? and How much urine do you lose each
time? Would you say drops, small splashes, or more (responses coded 13)? This questionnaire is scored by
multiplying responses to the 2 questions, and scores of 3 or greater are classied as at least moderately severe
urinary incontinence.37,38 In this study, urinary incontinence was dened as a score of at least 3.

Demographic Characteristics of Survey 1.13% of population. FI consisted of liquid stool in the


Participants majority of cases. Table 2 shows prevalence of FI by
composition and frequency of leakage per week. Incon-
The study population was made up of 7511 women tinence by more than one consistency was reported by
(51.3%) and 7248 men (48.7%). The mean (and median) 28% (95% CI, 26.529.3) of participants with FI.
age of the study participants was 49 years (standard Figure 1 shows the prevalence of FI by age group and
deviation, 18). All age groups were well-represented and gender. There was a linear upward trend in the overall
mirrored the overall U.S. population. Hispanic subjects
represented 13.4%, and non-Hispanic black subjects
Table 2. Prevalence of FI by Stool Type and Frequency of
were 10.18% of study population. Supplementary
Leakage
Table 1 shows the demographic characteristics of all
participants. Male Female Overall

Composition of leakage
Prevalence of Fecal Incontinence Solid 1.4 2.2 1.8
Mucus 2.77 3.2 3.0
Liquid 5.44 6.9 6.2
The overall prevalence of FI among civilian non-
Frequency of leakage (no. of bowel
institutionalized U.S. adults 20 years and older was movements per wk)
8.39% (95% CI, 7.769.05). This represents a total of <3 6.65 8.43 7.53
about 19 million non-institutionalized individuals in the 321 9.62 9.86 9.79
United States who report at least 1 episode of FI during 22 13.21 24.83 18.1
the last 30 days as of 2010. The prevalence of FI was
higher in women (9.4%; 95% CI, 8.810.27) than in men NOTE. Groups of subjects with different composition of leakage are not
(7.3%; 95% CI, 6.48.2). FI occurs at least weekly in mutually exclusive. All values are expressed as percents.
April 2014 Current Epidemiology of FI in the US 639

Figure 1. Overall preva-


lence of FI by age (years)
and sex. (A) Trends in
FI prevalence by sex;
(B) Trends in overall
prevalence.

prevalence of FI by age group (P trend < .001) and sex. 20072008 to 6.8% in 20092010, there was an upward
FI increased from 2.91% (95% CI, 2.223.81) in the 20- trend among women from 8.9% in 20052006 through
to 29-year-old subjects through 8.54% (95% CI, 9.6% in 20072008 to 10.0% in 20092010. Figure 2
7.389.87) in the 50- to 60-year-old subjects to 16.16% shows the trends in FI prevalence from 20052010 by
(95% CI, 14.1518.39) in those 70 years and older. age group. The greatest increase in FI prevalence was
observed in the 70 years and older group between the
years 20072008 and 20092010. Figure 3 shows the
Trends in Prevalence of Fecal Incontinence
trend in prevalence by gender and survey cycle. The
prevalence of the different types of FI did not vary
The prevalence of FI did not change during the study
signicantly during the 5 years.
period. The overall prevalence was 8.3 (95% CI, 7.29.5)
in 20052006, 8.5% (95% CI, 7.59.6) in 20072008,
and 8.4% (95% CI, 7.29.8) in the 20092010 survey. By Risk Factors Associated With Fecal
gender, although the prevalence of FI decreased among Incontinence
men from 7.7% in 20052006 through 7.3% in
Table 3 shows the bivariate and multivariate analysis
for factors associated with FI. The signicant limit for a
factor to be included in the multivariate model was set at
0.1. From the multivariate analysis, risk factors for FI
included age (>55 years), diabetes mellitus, male gender,
UI, frequent and loose stools, poor health status, and 3
chronic illnesses. Obesity, parity, and number of preg-
nancies were not associated with FI. To further explore
the reason for the switch from female to male gender (in
the multivariate) as risk factor, the model was built

Figure 3. Trends in FI prevalence by sex and survey cycle


Figure 2. Trends in FI from 20052010 by age group (years). from 20052010.
640 Ditah et al Clinical Gastroenterology and Hepatology Vol. 12, No. 4

Table 3. Bivariate and Multivariate Analysis for Factors Associated With FI

Bivariate analysis Multivariate analysis

Risk factor OR (95% CI) P value OR (95%) P value

Age group ( y)
2029 Baseline
3039 1.70 (1.212.40) .003 0.92 (0.501.71) >.05
4054 3.12 (2.244.34) <.001 1.48 (0.832.63) >.05
5569 4.56 (3.495.95) <.001 1.89 (1.073.37) .01
70 6.44 (4.738.76) <.001 2.05 (1.193.73) .003
Body mass index (kg/m2)
<25 Baseline
2529.9 0.95 (0.791.14) .56 0.91 (0.651.27) >.05
>30 1.30 (1.081.56) .006 1.01 (0.731.40) >.05
Self-reported health status
Good Baseline
Poor 1.21 (1.792.55) .06 1.32 (1.021.71) .04
Sex
Male Baseline
Female 1.28 (1.111.47) .001 0.67 (0.510.89) .006
Ethnicity
Hispanic Baseline
Non-Hispanic white 1.15 (0.981.35) .08 1.37 (0.981.94) >.05
Non-Hispanic black 1.12 (0.891.41) .31 1.00 (0.651.56) >.05
Marital status
Single Baseline
Divorced/separated 1.04 (0.781.40) .77 0.86 (0.481.34) >.05
Married 0.84 (0.671.06) .14 0.65 (0.440.98) >.05
Poverty index ratio
Above Baseline
Below 1.21 (1.011.47) .06 1.05 (0.791.39) >.05
Education
11th grade Baseline
High school 0.82 (0.680.97) .023 0.79 (0.551.13) >.05
<High school 1.01 (0.851.18) .95 0.95 (0.671.34) >.05
UI
No Baseline
Yes 1.65 (1.272.14) <.001 1.63 (1.222.17) .001
Diabetes mellitus
No Baseline
Yes 1.20 (1.061.35) .005 1.52 (1.112.07) .01
Physical activity
No Baseline
Yes 0.91 (0.821.01) .08 1.11 (0.821.51) >.05
Frequency of bowel movements (per wk)
<3 Baseline
320 0.67 (0.500.90) .009 0.97 (0.601.57) >.05
21 1.85 (1.322.59) .001 2.46 (1.414.29) .001
Stool consistency
Usual Baseline
Hard, lumpy 1.11 (0.821.50) .07 0.87 (0.521.46) >.05
Loose, watery 3.52 (2.844.36) <.001 2.52 (1.793.56) <.001
Vaginal deliveries (women only)
0 Baseline
13 1.03 (0.781.37) .83 n/a n/a
4 1.13 (0.831.54) .44 n/a n/a
Pregnancies
0 Baseline
13 1.15 (0.62.240) .67 n/a n/a
4 1.40 (0.434.60) .67 n/a n/a
Chronic illnesses
Baseline (none)
1 or 2 1.41 (1.151.72) .001 0.98 (0.701.36) >.05
3 2.47 (2.03.05) <.001 1.74 (1.252.42) .008

NOTE. Only variables found to be signicant in age-adjusted bivariate analyses with alpha threshold of 0.1 were included in the multivariate regression and shown
in this table. Multivariate odds ratios are adjusted for all other risk factors in the table.
n/a, not included in the multivariable logistic model.
April 2014 Current Epidemiology of FI in the US 641

forward by adding one variable at a time. We noted that transition to female predominance in the older age
this switch occurred when UI was introduced into the groups. From 2005 to 2010, the prevalence decreased
model. In addition, interactions between UI, age, and among men, whereas there was a steady increase among
gender did not yield statistically signicant effect modi- women. The reasons for these contrasting trends are
cation. However, effect modication between age and unclear. It has been speculated that obstetric injuries
gender was noted, with women being more likely to have probably contribute to the higher prevalence of FI
FI with increasing age (odds ratio, 1.02; P .03). among women.34,35 However, a number of studies have
failed to nd a consistent association between FI and
vaginal delivery.3,8,12,13,23,3638 This study showed that
Discussion number of vaginal deliveries or parity was not
associated with FI. Unfortunately, our data set did not
FI remains a common problem affecting 8.39%, ie, have information to specically assess the role of
approximately 19 million, of U.S. adults 20 years and older. operative deliveries or obstetric injury.
Economically, this translates into annual direct costs of One of our objectives was to identify risk factors for FI.
about 78 billion dollars.6,7 Estimates on the prevalence of Increasing age has been consistently shown to be associ-
FI have varied widely. These inconsistencies have been ated with FI.3,28,33,36,38,39 Some authors have argued that
mostly attributed to differences in sample populations this association is probably confounded by limited
and denitions of FI. Estimates from referral or specic mobility, multiple comorbidities, or overall poor health
subgroups of the populations overestimate the true status. We were able to adjust for most of these factors,
magnitude of FI. NHANES is a national population-based and yet age remained associated with FI. FI preventive
survey of U.S. residents. The rst national prevalence of strategies should focus on proper management of
FI among U.S. adults was reported in 2009.3 However, diabetes mellitus and control of diarrhea. There have
this study used data only from the NHANES 20052006 been studies showing that when FI exists in the context of
cycle, thus it is limited in numbers. Our study used data diarrhea, treating the latter often leads to improvement of
during 3 survey cycles and represents the largest sample the former.40,41 Having multiple comorbidities, considered
on FI at the population level in the United States. a surrogate for limited mobility, has been associated with
Estimates from this data set conrm previous ndings FI.3,22,23 We noted a similar association in this study.
from smaller studies conducted in the community Multiple illnesses probably impact physical ability to
around the United States.8,17,22,23 Studies conducted in carry out ones activities of daily living, including making
similar settings in Korea, Spain, and New Zealand found it to the restroom.
that the prevalence of FI was signicantly lower than Consistent with prior reports, we found a strong asso-
those reported from studies that targeted specic ciation between FI and UI.22,38 We believe that the strong
populations.2426 The study from New Zealand found a association between FI and UI likely reects a common
slightly higher prevalence of FI (12.4%).26 However, this etiologic pathway (common innervations)34,35,42 rather
study included both institutionalized and non- than either being a risk factor for the other. We found an
institutionalized individuals, whereas NHANES includes interesting relationship between FI, UI, and gender. In the
only non-institutionalized individuals. FI is one of the age-adjusted bivariate analysis, female gender was
primary reasons for admittance to nursing homes, and strongly associated with FI. Surprisingly, in the
higher rates have previously been reported.9,15,16,2629 multivariate analysis, men appeared to be at higher risk
We believe that the true prevalence of FI lies somewhere of FI. This switch was entirely explained by the presence
between the numbers reported in community-based of UI. This nding was not explained by effect
studies and those in long-term care centers. modication between UI and gender or age. However,
This study documents trends in the prevalence of FI effect modication was noted, with women being more
in the United States. We hypothesized that with the likely to have FI with increasing age. This result suggests
projected demographic changes in age in the United that all risk factor analysis studies on FI should take into
States, the prevalence of FI was on the rise. Our study consideration the presence or absence of UI.
showed that the prevalence of FI was relatively stable Recent reports have found a higher prevalence of FI
between 2005 and 2010. However, the prevalence among obese individuals.25,4346 Obesity might
increased steadily among the 70 years and older age contribute to FI by increasing the intra-abdominal
group during the study period, as shown in Figure 2. The pressures. In this study, obesity (body mass index >30
largest increase (3.0%, P < .001) in this age group kg/m2) was not associated with FI in a multivariate
occurred between 20072008 and 20092010. model. The association between obesity and FI is
Most discussions on the etiology of FI have been based controversial. Whereas some authors have noted an
on the assumption that women are more at risk than men. improvement in FI with weight loss,47 others have
Yet, several population-based studies have reported noted an increase.24 The association is even more
no gender differences3,23,28 or, surprisingly, a high complex in the context of bariatric surgery where an
prevalence in men.14,3033 In this study, we noted a male increased prevalence of FI has been described,
predominance in the younger age groups, with a gradual especially when diarrhea is present.43
642 Ditah et al Clinical Gastroenterology and Hepatology Vol. 12, No. 4

This study has several strengths. The majority of pre- 6. Miner PB Jr. Economic and personal impact of fecal and urinary
vious studies on FI have come from single institutions and incontinence. Gastroenterology 2004;126:S8S13.
were plagued by referral bias. Our sample is nationally 7. Xu X, Menees SB, Zochowski MK, et al. Economic cost of fecal
representative, with all segments of the population incontinence. Dis Colon Rectum 2012;55:586598.
including minorities well-represented. The standardization 8. Bharucha AE, Zinsmeister AR, Locke GR, et al. Prevalence and
of the NHANES survey procedure and denitions of FI en- burden of fecal incontinence: a population-based study in
sures high quality data collection. The NHANES survey women. Gastroenterology 2005;129:4249.
design also partially bypasses the drawback of previous 9. Dunivan GC, Heymen S, Palsson OS, et al. Fecal incontinence in
primary care: prevalence, diagnosis, and health care utilization.
studies, which is the underreporting of FI owing to patients
Am J Obstet Gynecol 2010;202:493496.
reluctance to voluntarily report this to care providers.14,33
10. Norton NJ. The perspective of the patient. Gastroenterology
Another strength of our study is the large number
2004;126:S175S179.
of subjects. The latter provides statistical power to study
11. Roberts RO, Jacobsen SJ, Reilly WT, et al. Prevalence of
factors associated with FI. A few limitations of this combined fecal and urinary incontinence: a community-based
study are worth mentioning. This analysis included only study. J Am Geriatr Soc 1999;47:837841.
non-institutionalized individuals. These estimates are 12. Borello-France D, Burgio KL, Richter HE, et al. Fecal and urinary
therefore an underestimation of the true magnitude of the incontinence in primiparous women. Obstet Gynecol 2006;
problem because a signicant proportion of individuals 108:863872.
with FI live in nursing homes.2,4,79 NHANES is a cross- 13. Makol A, Grover M, Whitehead WE. Fecal incontinence in
sectional design, and thus incidence and causality cannot women: causes and treatment. Womens Health (Lond Engl)
be established. 2008;4:517528.
14. Leigh RJ, Turnberg LA. Faecal incontinence: the unvoiced
symptom. Lancet 1982;1:13491351.
Conclusions 15. Rey E, Choung RS, Schleck CD, et al. Onset and risk factors for
fecal incontinence in a US community. Am J Gastroenterol
We have presented robust estimates of the preva- 2010;105:412419.
lence, trends, and risk factors of FI in a nationally 16. Nelson R, Furner S, Jesudason V. Fecal incontinence in Wis-
representative database of non-institutionalized adults in consin nursing homes: prevalence and associations. Dis Colon
the United States. We found that FI is a common disorder Rectum 1998;41:12261229.
in the United States, affecting about 19 million in- 17. Nelson RL. Epidemiology of fecal incontinence. Gastroenter-
dividuals as of April 2010. The prevalence of FI remained ology 2004;126:S3S7.
relatively stable between 2005 and 2010. Loss of liquid 18. Rockwood TH. Incontinence severity and QOL scales for fecal
stool is the most common type of FI. Preventive strate- incontinence. Gastroenterology 2004;126:S106S113.
gies should focus on diabetes control and management of 19. Lewis SJ, Heaton KW. Stool form scale as a useful guide
diarrhea. Future studies on the risk factors for FI should to intestinal transit time. Scand J Gastroenterol 1997;
32:920924.
consider presence or absence of UI.
20. Degen LP, Phillips SF. How well does stool form reect colonic
transit? Gut 1996;39:109113.
Supplementary Material 21. Heaton KW, ODonnell LJ. An ofce guide to whole-gut transit
time: patients recollection of their stool form. J Clin Gastro-
Note: To access the supplementary material accom- enterol 1994;19:2830.
panying this article, visit the online version of Clinical 22. Goode PS, Burgio KL, Halli AD, et al. Prevalence and correlates
of fecal incontinence in community-dwelling older adults. J Am
Gastroenterology and Hepatology at www.cghjournal.org,
Geriatr Soc 2005;53:629635.
and at http://dx.doi.org/10.1016/j.cgh.2013.07.020.
23. Perry S, Shaw C, McGrother C, et al. Prevalence of faecal in-
continence in adults aged 40 years or more living in the com-
References munity. Gut 2002;50:480484.
1. Bharucha AE. Fecal incontinence. Gastroenterology 2003; 24. Kang HW, Jung HK, Kwon KJ, et al. Prevalence and predictive
124:16721685. factors of fecal incontinence. J Neurogastroenterol Motil 2012;
2. Nelson RL, Furner SE. Risk factors for the development of fecal 18:8693.
and urinary incontinence in Wisconsin nursing home residents. 25. Pares D, Vallverdu H, Monroy G, et al. Bowel habits and fecal
Maturitas 2005;52:2631. incontinence in patients with obesity undergoing evaluation for
3. Whitehead WE, Borrud L, Goode PS, et al. Fecal incontinence in weight loss: the importance of stool consistency. Dis Colon
US adults: epidemiology and risk factors. Gastroenterology Rectum 2012;55:599604.
2009;137:512517. 26. Sharma A, Marshall RJ, Macmillan AK, et al. Determining
4. Crowell MD, Schettler VA, Lacy BE, et al. Impact of anal in- levels of fecal incontinence in the community: a New Zealand
continence on psychosocial function and health-related quality cross-sectional study. Dis Colon Rectum 2011;
of life. Dig Dis Sci 2007;52:16271631. 54:13811387.
5. Drossman DA, Li Z, Andruzzi E, et al. U.S. householder survey 27. Chassagne P, Landrin I, Neveu C, et al. Fecal incontinence in the
of functional gastrointestinal disorders: prevalence, socio- institutionalized elderly: incidence, risk factors, and prognosis.
demography, and health impact. Dig Dis Sci 1993;38:15691580. Am J Med 1999;106:185190.
April 2014 Current Epidemiology of FI in the US 643

28. Kalantar JS, Howell S, Talley NJ. Prevalence of faecal inconti- 40. Bliss DZ, Jung HJ, Savik K, et al. Supplementation with dietary
nence and associated risk factors: an underdiagnosed problem ber improves fecal incontinence. Nurs Res 2001;50:203213.
in the Australian community? Med J Aust 2002;176:5457. 41. Palmer KR, Corbett CL, Holdsworth CD. Double-blind cross-
29. Varma MG, Brown JS, Creasman JM, et al. Fecal incontinence in over study comparing loperamide, codeine and diphenoxylate in
females older than aged 40 years: who is at risk? Dis Colon the treatment of chronic diarrhea. Gastroenterology 1980;
Rectum 2006;49:841851. 79:12721275.
30. Campbell AJ, Reinken J, McCosh L. Incontinence in the elderly: 42. Pezzone MA, Liang R, Fraser MO. A model of neural cross-talk
prevalence and prognosis. Age Ageing 1985;14:6570. and irritation in the pelvis: implications for the overlap of chronic
31. Denis P, Bercoff E, Bizien MF, et al. [Prevalence of anal incon- pelvic pain disorders. Gastroenterology 2005;128:19531964.
tinence in adults]. Gastroenterol Clin Biol 1992;16:344350. 43. Bharucha AE. Incontinence: an underappreciated problem in
32. Kok AL, Voorhorst FJ, Burger CW, et al. Urinary and faecal in- obesity and bariatric surgery. Dig Dis Sci 2010;55:24282430.
continence in community-residing elderly women. Age Ageing 44. Erekson EA, Sung VW, Myers DL. Effect of body mass index on
1992;21:211215. the risk of anal incontinence and defecatory dysfunction in
33. Thomas TM, Egan M, Walgrove A, et al. The prevalence of faecal women. Am J Obstet Gynecol 2008;198:596-4.
and double incontinence. Community Med 1984;6:216220. 45. Markland AD, Richter HE, Burgio KL, et al. Fecal incontinence in
34. Madoff RD, Williams JG, Caushaj PF. Fecal incontinence. N Engl obese women with urinary incontinence: prevalence and role of
J Med 1992;326:10021007. dietary ber intake. Am J Obstet Gynecol 2009;200:566.
35. Small KA, Wynne JM. Evaluating the pelvic oor in obstetric 46. Wasserberg N, Haney M, Petrone P, et al. Fecal incontinence
patients. Aust N Z J Obstet Gynaecol 1990;30:4145. among morbid obese women seeking for weight loss surgery:
36. MacLennan AH, Taylor AW, Wilson DH, et al. The prevalence of an underappreciated association with adverse impact on quality
pelvic oor disorders and their relationship to gender, age, parity of life. Int J Colorectal Dis 2008;23:493497.
and mode of delivery. BJOG 2000;107:14601470. 47. Markland AD, Richter HE, Burgio KL, et al. Weight loss improves
37. Markland AD, Kraus SR, Richter HE, et al. Prevalence and fecal incontinence severity in overweight and obese women with
risk factors of fecal incontinence in women undergoing stress urinary incontinence. Int Urogynecol J 2011;22:11511157.
incontinence surgery. Am J Obstet Gynecol 2007;
197:662667.
Reprint requests
38. Melville JL, Fan MY, Newton K, et al. Fecal incontinence in US Address requests for reprints to: Ivo Ditah, MD, MPhil, Division of Gastroen-
women: a population-based study. Am J Obstet Gynecol 2005; terology and Hepatology, Mayo Clinic and Foundation, 200 First Street SW,
193:20712076. Rochester, Minnesota 55905. e-mail: Ditah.ivo@mayo.edu; fax: (507)
284-0538.
39. Townsend MK, Matthews CA, Whitehead WE, et al. Risk factors
for fecal incontinence in older women. Am J Gastroenterol 2013; Conicts of interest
108:113119. The authors disclose no conicts.
643.e1 Ditah et al Clinical Gastroenterology and Hepatology Vol. 12, No. 4

Supplementary Figure 1. Survey cycle invitees and response rate regarding FI questionnaire.
April 2014 Current Epidemiology of FI in the US 643.e2

Supplementary Table 1. Characteristics of Study Participants

Characteristics Male (%) Female (%) Total (%)

Sex
Age group (y) 7248 (48.74) 7511 (51.26) 14,759 (100)
2029 1193 (19.67) 2597 (17.99) 2597 (18.81)
3039 1210 (18.65) 1241 (17.57) 2451 (18.1)
4054 1877 (31.66) 1936 (31.22) 3813 (31.44)
5569 1663 (19.9) 1662 (20.61) 3325 (20.27)
70 1305 (10.12) 1268 (12.61) 2573 (11.4)
Race (ethnicity)
Hispanic 1890 (13.37) 2076 (11.74) 3966 (12.53)
Non-Hispanic white 3631 (71.02) 3637 (71.05) 3966 (71.03)
Non-Hispanic black 1437 (10.18) 1492 (11.73) 2929 (10.97)
Other 290 (5.44) 306 (5.48) 596 (5.46)
Education level
<High school 2942 (37.19) 2984 (36.03) 5926 (36.59)
High school 965 (6.82) 819 (5.30) 1784 (6.04)
>High school 3336 (55.9) 3697 (58.59) 7033 (57.3)
Marital status
Married 4844 (68.77) 4188 (61.58) 9032 (65.09)
Divorced/separated/widow 1187 (13.26) 2135 (23.19) 3322 (18.35)
Never married 1213 (17.93) 1184 (15.15) 2397 (1.5)
Poverty index ratio
Below 1303 (28.21) 1167 (25.14) 2470 (26.64)
Above 5424 (71.79) 5784 (74.86) 11,208 (73.36)
Self-reported health status
Good 5589 (83.7) 5683 (82.83) 11,272 (83.25)
Poor 1658 (16.29) 1827 (17.16) 3485 (16.75)
UI
Yes 381 (39.2) 852 (32.910) 1233 (34.36)
No 701 (60.8) 2142 (67.09) 2848 (65.64)
Body mass index (kg/m2)
<25 1918 (26.65) 2279 (35.81) 4197 (31.35)
2529.9 2824 (39.46) 2194 (28.16) 5018 (33.66)
>30 2431 (33.89) 2971 (36.04) 5402 (34.99)
Physical activity
No activity 3455 (42.12) 4389 (52.63) 7844 (47.51)
Moderate 1661 (24.7) 1958 (28.68) 3619 (26.74)
Vigorous 2132 (33.18) 1164 (18.69) 3296 (25.75)
Frequency of bowel movements (per wk)
<3 3591 (4.2) 844 (11.33) 1203 (7.86)
320 6312 (88.22) 6202 (83.43) 12,514 (85.76)
21 577 (7.58) 465 (5.2) 1042 (6.38)
Diabetes mellitus
Yes 854 (8.12) 861 (8.27) 1715 (8.2)
No 6240 (89.9) 6522 (90.09) 12,762 (90.01)
Chronic illnesses
None 3449 (52.1) 3144 (43.68) 6593 (47.78)
12 2936 (39.06) 3392 (44.67) 6328 (41.94)
3 or more 863 (8.84) 975 (11.65) 1838 (10.28)

NOTE. All results are reported as n (%). Respondents with missing data, refused, or responded with dont know were excluded from the table.

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