Name: _________________________________ Date: ________________________ Class: ___________

Transcription Internet Activity

Log on to your computer

Pull up the internet and go to:

http://phschool.com/science/biology_place/biocoach/index.html

Under Bio-coach activities choose: From Gene to Protein: Transcription

1. Read the Introduction. What is transcription? ________________________________________

________________________________________________________________________________________________

2. Click on “next concept.” Read about the Central Dogma. What is Central Dogma?____________

_________________________________________________________________________________________________________

_________________________________________________________________________________________________________

What enzyme synthesizes RNA?_____________________________________________________________________

What are the two steps in protein synthesis?______________________________________________________

3. Click on “next concept.” Read about transcription and translation in prokaryotic and

eukaryotic cells. What does it mean for transcription and translation to be coupled in

prokaryotes?__________________________________________________________________________________________

_________________________________________________________________________________________________________

In eukaryotes, transcription occurs in ________ and translation occurs in the ___________.

What is the difference in pre-mRNA and mature mRNA?_________________________________

________________________________________________________________________________________________.
4. Click on “next concept.” Read about different genes for different RNA’s. Name the four

types of RNA and their functions.___________________________________________________________________

_________________________________________________________________________________________________________

_________________________________________________________________________________________________________

_________________________________________________________________________________________________________

5. Click on “next concept.” Read about the basic structure of a protein-coding gene. What are

the three parts of a protein-coding gene? __________________________________________________________

Name: _________________________________ Date: ________________________ Class: ___________

_________________________________________________________________________________________________________
_________________________________________________________________________________________________________
6. Click on “next concept.” Read about the RNA molecule. Compare DNA to RNA in the
following ways.

Sugar: DNA___________________ RNA________________________

Bases: DNA___________________ RNA ________________________

Polynucleotide structure: DNA ____________________ RNA ______________________

7. Click on “review” (at the top right of the page) Look at the chemistry of the nitrogenous

bases.

How are thymine and uracil similar? ____________________________________________________

If uracil is found in mRNA, what DNA nucleotide was it made from? __________________________

What is the difference between ribose and deoxyribose? ___________________________________

____________________________________________________________________________________________________

8. Click on “next” at the bottom of the review page. Read about the chemistry of DNA and
RNA polynucleotide chains.
-close review page-
9. Click on “next concept.” Read about the transcription process. What must happen to the

DNA strands first for RNA synthesis to occur?___________________________________________

In what direction is the RNA molecule synthesized?__________________________________

A, T, G, and C on the DNA specify what nucleotides on the RNA? ________________________

10. Click on “review.” Read about RNA polymerase.

11. Click on “next” at the bottom of the review page. Read about biosynthesis of RNA. What

bonds hold the strand of RNA nucleotides together? _________________________________________

Name: _________________________________ Date: ________________________ Class: ___________

12. Click on “next” at the bottom of the review page. Read about transcription initiation and

promoters. Summarize. ___________________________________________________________

______________________________________________________________________________

Close review page

13. Click on “Practice.” Work with the interactive figure to transcribe the DNA.

14. Click on “next concept.” What is the significance of the promoter? ________________________

15. Click on “next concept.” In prokaryotes, what is the relationship between the mRNA

transcribed and the one translated?___________________________________________________________

16. Click on “next concept.” Read about the mRNA in eukaryotes. What must happen to

transcribed mRNA before it can be translated un

eukaryotes?______________________________________

______________________________________________________________________________

What is the name of the amino acid coding sequences?

Where does mRNA editing or processing occur?

17. Click on “review.” What other two modifications are made on eukaryotic mRNA before it

can leave the nucleus (other than removing introns)? ___________________________________

____________________________________________________________________________

What is the function of the 5’ cap?_______________________________________________

What is the function of the poly (A) tail?__________________________________________

18. Click on “next concept.” Read about splicing. What are snRNP’s? ______________________

____________________________________________________________________________

19. Click on “review.” Watch the animation of pre-mRNA splicing.

20. Click on “self Quiz.” Take the self quiz. I would take notes!

Log off or shut down the computer according to your teachers instructions.
Name: _________________________________ Date: ________________________ Class: ___________