[KT 542] AUGUST 2008 Sub.

Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. What is Metastasis.
What are the different pathways of spread?
Write in detail about one of the pathways
2. Define anemia.
Discuss etiopathogenesis with blood and bone morrow picture in iron deficiency
anemia.

II. Write Short notes on : (10 x 5 = 50)

1. Free radicals.
2. Wilm’s tumour.
3. Klinefelter syndrome.
4. Oncogenic viruses.
5. Rhinosporidiosis.
6. Ricketts.
7. Fine Needle Aspiration Cytology
8. Leukemoid reaction.
9. Idiopathic thrombocytopenic purpura.
10. Erythrocyte sedimentation rate.

III. Short Answer Questions : (10 x 2 = 20)

1. What are the different types of necrosis?
2. Mention 4 factors influencing wound healing.
3. Fate of thrombi.
4. Enumerate 4 types of chromosomal rearrangements.
5. Mention 2 Examples of tumor suppressor genes.
6. Mention any 4 childhood malignancies.
7. What are red cell indices?
8. Blood picture in magaloblastic anemia.
9. Mention important investigations necessary for diagnosis of Hemophilia.
10. Define Leukemia.
********
[KU 542] FEBRUARY 2009 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define and classify oedema? Discuss Aetio-Pathogenesis and pathology of various
types of oedema with examples?.
2. 40 years male H/o chronic fatigue, weight loss since 6 months. O/E pallor, marked
splenomegaly+, laboratory report shows Hb 10 GM%, TC 215000/CMM.
Platelets 4 laks/cmm. Answer the following:
a) What is your diagnosis?
b) What is common genetic abnormality?
c) Blood and Bone Marrow findings to confirm your diagnosis?
d) Prognosis of the condition?
II. Write Short notes on : (10 x 5 = 50)
1. Chemical mediators of acute inflammation.
2. Thrombo-embolism.
3. Pathological calcification.
4. Trisomy – 21.
5. Immune complex hypersensitivity (Type III) reactions.
6. Laboratory diagnosis of cancer.
7. Von-Willebrand’s disease.
8. Haemolytic disease of newborn.
9. Grading and staging of tumors.
10. Automatic tissue processor.
III. Short Answer Questions : (10 x 2 = 20)
1. Difference between exudates and transudate.
2. Microscopic picture of acute appendicitis.
3. Mast cells.
4. Mention four neuclear changes in Necrosis.
5. Significance of casts in urine.
6. Anti-Coagulants.
7. Mention four indications of bone marrow aspiration.
8. Reticulocyte count.
9. Henoch – Schonlein purpura.
10. Gross appearance of Mycetoma foot.
*******
[KV 542] AUGUST 2009 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define shock, enumerate types of shock and discuss pathogenesis and
morphological changes in shock.
2. Mention Oncogenic viruses. Describe Oncogenesis by human papilloma virus.

II. Write Short notes on : (10 x 5 = 50)

1. Tumor markers.
2. Amyloidosis.
3. Blood and bone marrow picture in B12 deficiency anaemia.
4. Types of embolism. Write on caisson disease.
5. Leprosy.
6. Evidences of haemolytic anaemia.
7. F A B classification of leukemia.
8. Mechanism of autoimmune diseases.
9. Chemical mediators.
10. Silicosis.

III. Short Answer Questions : (10 x 2 = 20)

1. Fate of thrombus.
2. F.N.A.C.
3. Modes of spread of tumors.
4. Draw – Megaloblast, Maxicanhat cell, Pessary cell, Macropolycyte.
5. Types of nectrosis with examples.
6. Ketone Bodies.
7. Tests for sickling.
8. Virchow’s triad.
9. Differences between benign and malignant tumors.
10. Bombay blood group.
*******
[KW 542] FEBRUARY 2010 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define Oedema. Discuss the pathophysiology of oedema.
Add a note on pulmonary oedema.
2. Define and classify Leukemias.
Describe the blood and bone morrow findings in chronic myeloid leukemia.

II. Write Short notes on : (10 x 5 = 50)

1. Phagocytosis.
2. Haematocrit.
3. Sickle cell.
4. Tumour suppressor genes.
5. Anaphylactic reaction.
6. Down’s syndrome.
7. Metaplasia.
8. Kwashiorkar.
9. Mycetoma.
10. Eosinophilia.

III. Short Answer Questions : (10 x 2 = 20)

1. Name four causes of fatty liver.
2. State four differences between dry and wet gangrenes.
3. Define atrophy. Give two examples to physiological atrophy.
4. Describe four staining character of amyloid.
5. Microscopic appearance of lepromatous leprosy.
6. Name two opportunistic infections and two neoplasms seen in AIDS.
7. Name two human oncogenic viruses and tumours caused by them
8. Blood components prepared in a blood bank.
9. What is a Reticulocyte? Mention two causes of reticulocytosis.
10. What is cross matching?

*******
[KX 542] AUGUST 2010 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define inflammation.
Describe the major events of acute inflammation with a note on defective Leukocyte
function.
2. Enumerate the various carcinogenic agents.
Classify the chemical carcinogens and describe the steps involved in chemical
carcinogenesis.

II. Write Short notes on : (10 x 5 = 50)

1. Free Radical Injury.
2. Septic Shock.
3. Rickets.
4. Tertiary Syphilis.
5. Proteins in urine.
6. Cardiac edema.
7. Klinefelter syndrome.
8. Type I hypersensitivity reaction.
9. Factors affecting wound healing.
10. Apoptosis.

III. Short Answers Questions: (10 x 2 = 20)

1. Sago Spleen.
2. Paraneoplastic syndromes.
3. ESR.
4. Coomb’s Test.
5. Reed Sternberg Cell
6. Hemophilia.
7. Metaplasia.
8. CVC liver.
9. Blood picture in megaloblastic Anemia.
10. CSF in tuberculous meningitis.
*******
[KY 542] FEBRUARY 2011 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define Necrosis. Name the different types of necrosis.
Discuss in detail with examples the different types of necrosis.
Differentiate between Necrosis and Apoptosis.
2. A 70 year old women admitted with worsening anemia and pathological fracture of
the Humerus had an ESR of 120mm in 1 hour. Her peripheral smear showed
increased rouleaux formation. Xray of skull showed multiple punched out osteolytic
lesions.
a. What is the most probable diagnosis? Write briefly on the etiopathogenesis of this
disease.
b. Describe the Bone Marrow Changes in this disease.
c. Enumerate the common laboratory investigations for this disease.
d. Enlist the complications of this disease.
II. Write Short notes on : (10 x 5 = 50)
1. Role of Arachidonic Metabolites in inflammation.
2. Pathogenesis of Septic Shock.
3. Tumour Metastasis.
4. Mitochondrial Inheritance.
5. Etiopathogenesis of Cystic Fibrosis.
6. Anemia of Chronic Disease.
7. FAB classification of Acute Leukemia.
8. Idiopathic Thrombocytopenic purpura.
9. Transfusion Reaction.
10. Hematocrit.
III. Short Answer Questions : (10 x 2 = 20)
1. Give four examples for pathological calcification.
2. Give four examples for Metaplasia.
3. Mention two differences between exudates and transudate.
4. Mention two renal changes in SLE.
5. Give two examples for trace elements and their deficiency states.
6. Give four causes for iron deficiency anaemia.
7. Mention two important marrow changes in B12 deficiency.
8. Two characteristic difference between Myeloblasts and Lymphoblasts.
9. Mention two pathognomonic features of Hairy cell leukemia.
10. Mention four applications of reticulocyte count.

*******
[KZ 542] AUGUST 2011 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper III – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define inflammation.
Write in detail about the vascular and cellular changes in inflammation.
2. 40 yrs female c/o loss of weight, huge splenomegaly with peripheral blood white
blood cell count of more than 1 lakh cells/cc
a. What is the probable diagnosis?
b. What are the characteristic peripheral smear findings?
c. What is the course of the disease?
d. What is the chromosomal abnormality involved?

II. Write Short notes on : (10 x 5 = 50)

1. Classify pigments and write about Lipofuschin.
2. Write about outcomes of acute inflammation.
3. Growth factors.
4. Hybridisation techniques to detect genomic alterations.
5. Antibody mediated hypersensitivity.
6. Molecular basis of cancer.
7. Immunology of Leprosy.
8. Primary myelofibrosis.
9. Hemophilia A.
10. Peripheral smear and Bone marrow findings in Multiple Myeloma.
III. Short Answer questions : (10 x 2 = 20)
1. Define metaplasia and give two examples.
2. Antiphospholipid antibody syndrome.
3. Mention four X linked recessive disorders.
4. Mention four special stains for Amyloid.
5. Lead and blood and marrow changes.
6. Four infections associated with AIDS.
7. Hamartoma.
8. Prions.
9. Four Systemic effects of inflammation.
10. Hyper IGM syndrome.
*******
[LA 542] FEBRUARY 2012 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time: Three Hours Maximum: 40 Marks
Answer ALL questions in the same order.
Draw Suitable diagrams wherever necessary
I. Elaborate on :
1. Define shock. Discuss in detail the pathogenesis of septic shock.
Describe the morphology of kidneys and lungs affected by shock. (10 x 1 = 10)
2. 60 yrs male presented with normocytic normochromic anaemia, pathological fracture
femur and proteinura. X ray skull revealed punched out lesions in the calvarium and
peripheral smear studied show rouleaux formation.
a) What is your probable diagnosis.
b) Discuss in detail the molecular pathogenesis, morphology and clinical features of
above said disorder. (5 x 1 = 5)
II. Write notes on : (10 x 1.5 = 15)
1. Turner syndrome.
2. Immune complex mediated hypersensitivity.
3. Differentiation and anaplasia.
4. Viral haemorrhagic fevers.
5. Morphology of leprosy.
6. Morphology of primary myelo fibrosis.
7. Pathogenesis of sickle cell disease.
8. Chronic immune thrombocytopaenic purpura.
9. Free radicals
10. Defects in leucocyte function.
III. Short Answers on : (10 x 1 = 10)
1. Fat necrosis.
2. Heart failure cells.
3. Lines of zahn.
4. Warburg effect.
5. Mott cells.
6. 4 tumors associated with AIDS.
7. Cross matching.
8. Anticoagulants.
9. PSEDO PELGER HUET ANOMALY.
10. Black water fever.
*******
[LB 542] AUGUST 2012 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: Pages Time Marks
(Max.) (Max.) (Max.)
1. Write in detail about carcinogenesis physical, chemical
and biological and also molecular basis of Carcinogenesis. 16 30 10
2. Chronic myeloid leukemia – clinical features peripheral
smear and bone marrow findings and clinical outcome. 8 20 5

II. Write notes on:

1. Air embolism. 3 8 1.5
2. Kline felters syndrome. 3 8 1.5
3. Arthus reaction. 3 8 1.5
4. Morphology of Primary Tuberculosis. 3 8 1.5
5. Fracture healing. 3 8 1.5
6. Sickle cell disease. 3 8 1.5
7. Poycythemia vera. 3 8 1.5
8. Leukemoid reaction. 3 8 1.5
9. Christmas disease. 3 8 1.5
10. Fanconi’s Anemia. 3 8 1.5

III. Short answers on:

1. Warthin finkeldey giant cells. 2 5 1
2. Factors downregulation apoptosis. 2 5 1
3. Gamma – Gandy bodies. 2 5 1
4. Virchow’s traid. 2 5 1
5. Bernard – soulier syndrome. 2 5 1
6. Sago spleen. 2 5 1
7. Two special stain for Amyloid. 2 5 1
8. Howell – Jolly bodies. 2 5 1
9. Tear drop cell. 2 5 1
10. MCV. 2 5 1
*******
[LC 542] FEBRUARY 2013 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time: Three Hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 15 = 30)
1. Define edema.
Discuss the etiopathogenesis of various types of edema with examples.
2. Define and classify anaemia.
Discuss etiopathogenesis, peripheral smear and bone marrow picture in iron
deficiency anaemia.
II. Write notes on : (10 x 5 = 50)
1. Oncogenic viruses.
2. Anaphylactic reaction
3. Bence jones proteins.
4. Pathologic Calcification
5. Vitamin A Deficiency.
6. Neonatal respiratory distress syndrome.
7. Von Willebrand’s Disease.
8. Granulomatous inflammation
9. Familial hypercholesterolemia.
10. Embolism.

III. Short Answers on: (10 x 2 = 20)

1. Types of necrosis.
2. Factors influencing wound healing.
3. Fate of thrombus.
4. Clinical features of Trisomy 21.
5. Oncofetal antigens.
6. Reticulocyte.
7. Philadelphia chromosome.
8. Reed-Sternberg cell.
9. Tertiary Syphilis.
10. Agranulocytosis.
*******
[LD 542] AUGUST 2013 Sub. Code : 4063

SECOND M.B.B.S. DEGREE EXAMINATION

Paper I – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time: Three Hours Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. a) 23 yrs female presented with oral ulcers, malar rash photosentivity and non erosive
arthritis involving both knees. Laboratory investigations show persistent proteinuria
and leucopenia. What is your probable diagnosis.
b) Discuss in detail the pathogenesis and morphology of kidney affected by the above
disorder.
2. Discuss in detail the molecular pathogenesis and morphology of Hodgkin lymphoma.

II. Write notes on: (10 x 1.5 = 15)

1. Caseous necrosis.
2. Pathology of Fracture healing.
3. Morphology of Thrombi.
4. Familial hypercholesterolemia.
5. Oncogenic Epstein – Barr virus.
6. Pathogenesis of Amyloidosis.
7. Aetiology and morphology of bone marrow in Aplastic anaemia.
8. Morphology of multiple myeloma.
9. Molecular pathogenesis of Acute myeloid leukaemia.
10. Pathogenesis of disseminated intra vascular coagulation.

III. Short Answers on: (10 x 1 = 10)

1. Define metaplasia & give 2 examples.
2. Tigered effect.
3. Define Granuloma.
4. Systemic factors that influence wound healing.
5. Warburg effect.
6. Role of Vitamin C in wound healing.
7. Prothrombin time.
8. Megalobast.
9. Rh factor.
10. Auer rods.
*******
[LE 542] FEBRUARY 2014 Sub. Code: 4063

SECOND YEAR MBBS DEGREE EXAMINATION

Paper V – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code: 524063
Time: Three Hours Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. Define thrombosis, write in detail about pathogenesis, causes, morphology and fate
of thrombus.

2. 40 yr old male presented with h/o fever, vomiting and diarrhoea.

Patient had temperature of 103 degrees F. Weak rapid pulse, hypotension,
tachypnoea, cold, clammy, cyanotic skin. Blood culture gram negative bacterial
infection positive.
(a) What is your diagnosis?
(b) Explain the pathogenesis and morphology.

II. Write Notes on: (10 x 1.5 = 15)

1. Definition and characteristics of types of necrosis.
2. Phagocytosis.
3. Paraneoplastic syndromes.
4. Gaucher’s disease.
5. Hypersensitivity reaction II
6. Morphological changes in apoptosis.
7. Vascular events in acute inflammation.
8. Chemokines.
9. Morphology of infarct.
10. Opportunistic infections in AIDS.

III. Short Answers on: (10 x 1 = 10)

1. Write any two stem cell niches.
2. Heinz bodies.
3. Types of leprosy.
4. Mention the cause of thrombocytopenia.
5. Bart haemoglobin.
6. Types of wound healing.
7. Two inherited disorders of platelets.
8. Two oncogenic DNA virus.
9. Two tumor suppressor genes.
10. Two examples of acute phase proteins.

*******
[LF 542] AUGUST 2014 Sub. Code: 4063

SECOND YEAR M.B.B.S DEGREE EXAMINATION

Paper V – GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code: 524063
Time: Three Hours Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. a) A 12 year boy weighing 70 kgs, doesn’t play any outdoor games and is
always in front of his play station with lot of snacks besides him.
What is he having? What are the methods to assess it?
b) What is the etiopathogenesis? Enumerate the complications?
2. Define Thrombocytopenia? Classify causes of Thrombocytopenia?
Discuss various tests in evaluating bleeding disorders?

II. Write Notes on: (10 x 1.5 = 15)

1. Define Virchow’s triad?
2. Outcomes of acute inflammation?
3. Caissons disease
4. Morphology of renal changes in SLE
5. P 53
6. Epstein barr virus
7. Leucocyte alkaline phosphatase
8. Hemophilia A
9. Wilms Tumor
10. Amniotic fluid embolism.
III. Short Answers on: (10 x 1 = 10)
1. Russell bodies
2. Mention two sites of biopsy for amyloidosis?
3. Autosomal recessive hematopoietic disorder
4. Special stain to diagnose Gaucher’s disease
5. Fluorescent in situ hybridization
6. Name two trisomy syndromes
7. Neurofibromatosis gene
8. Name two familial cancers?
9. Stages of shock
10. Mention two sites of oncocytomas.

*******
[LG 542] FEBRUARY 2015 Sub.Code :4063

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER V – GENERAL PATHOLOGY & HAEMATOLOGY

Q.P. Code: 524063

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify Hemolytic Anemias. Write in detail about the pathogenesis, blood

picture and clinical features of beta Thalassemia major.

II. Write notes on: (4 x 5 = 20)

1. Growth factors
2. Transplant rejection
3. Cystic fibrosis.
4. Hodgkin Lymphoma

III. Short answers on: (5 x 2 = 10)

1. Dystrophic calcification
2. Gaucher’s cell
3. Arthus reaction
4. Chloroma
5. Vitamin C deficiency
********
[LH 542] AUGUST 2015 Sub. Code: 4063

SECOND M.B.B.S. DEGREE EXAMINATION

PAPER V – GENERAL PATHOLOGY & HAEMATOLOGY
Q.P. Code: 524063
Time : Three Hours Maximum : 40 marks
Answer ALL questions
I. Elaborate: (1 x 10 = 10)
1. Define Neoplasia. Write in detail about the molecular basis of cancers.
Add a note on Oncogenes and their mode of activation.

II. Write notes on : (4 x 5 = 20)

1. Pathogenesis of shock.

2. Amyloidosis.

3. Megaloblastic Anemia.

4. Myelofibrosis.

III. Short answers on : (5 x 2 = 10)

1. Acute phase reactants.

2. Le cell.

3. Chronic granulomatous disease.

4. Langerhans cell histiocytosis.

5. Name four Monoclonal Gammopathies.

*******
[LI 542] FEBRUARY 2016 Sub. Code: 4063

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER V – GENERAL PATHOLOGY & HAEMATOLOGY
Q.P. Code : 524063
Time : Three Hours Maximum : 40 Marks
Answer ALL questions
I. Elaborate on: (1 x 10 = 10)
1. Define apoptosis. What are the causes of apoptosis?
Write about the biochemical features and mechanisms of apoptosis.
Add a note on dysregulated apoptosis.

II. Write notes on: (4 x 5 = 20)

1. Embolism.

2. Stem cells in tissue homeostasis.

3. Myelodysplastic syndrome.

4. Von willebrand disease.

III. Short answers on: (5 x 2 = 10)

1. Role of sirutins in cellular aging.

2. Wilson’s disease.

3. Sea blue histiocytosis.

4. Agranulocytosis.

5. Lead poisoning.

*******
[LJ 542] AUGUST 2016 Sub. Code : 4063

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER V – GENERAL PATHOLOGY & HAEMATOLOGY
Q. P. Code : 524063
Time : Three hours Maximum: 40 Marks
Answer ALL questions.
I. Elaborate on : (1 x 10 = 10)
1. Describe the pathogenesis, morphology and clinical features of tuberculosis.

II. Write notes on: (4 x 5 = 20)

1. Gangrene.

2. Blood picture of chronic myeloid leukemia.

3. Disseminated intravascular coagulation.

4. Down syndrome.

III. Short answers on: (5 x 2 = 10)

1. Name four cell derived mediators of inflammation.

2. Differences between benign and malignant tumor.

3. Reed Sternberg cell and its variants.

4. Define hyperemia and congestion.

5. Four opportunistic infections in HIV.

*******
[LK 542] FEBRUARY 2017 Sub.Code :5065

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER V – PATHOLOGY – I (GENERAL PATHOLOGY &
HAEMATOLOGY)

Q.P. Code: 525065

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. List the causes of megaloblastic anemia. Discuss about the pathogenesis,

morphology and bone marrow picture of megaloblastic anemia.

II. Write notes on: (4 x 5 = 20)

1. Morphological patterns of tissue necrosis.

2. Tumor markers.
3. Klinefelter syndrome.
4. Haemophilia.

III. Short answers on: (5 x 2 = 10)

1. Metaplasia.
2. Lipoxins.
3. Morphology of thrombi.
4. Conditions associated with protein energy malnutrition.
5. Russell bodies.

********
 [LL 542] AUGUST 2017 Sub.Code :5065

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER V – PATHOLOGY – I (GENERAL PATHOLOGY &
HAEMATOLOGY)

Q.P. Code: 525065

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Define edema. Tabulate the pathophysiological categories of edema and write in

detail about each category with suitable examples and illustrations.

II. Write notes on: (4 x 5 = 20)

1. Write about causes of cell injury and write briefly about hyperplasia with suitable
examples.
2. Write briefly about idiopathic thrombocytopenic purpura – pathophysiology,
morphology and investigatory findings.
3. Write about dystrophic and metastatic calcification.
4. Type III hypersensitivity reaction.

III. Short answers on: (5 x 2 = 10)

1. Enumerate four risk factors for DIC.

2. Morphology of granuloma.
3. Name the stages of shock.
4. Name four virus implicated in carcinogenesis.
5. Reticulocyte.

*********
[KT 543] AUGUST 2008 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Describe etiopathogenesis of diabetes. What are the complications?
2. 40 year female presents with post coital bleeding and foul smelling discharge per
vagina. She lost 15% wt in 2 months, with loss of appetite.
a. What is your diagnosis ?
b. What etiopathogenesis of this condition?
c. What are the morphological features?
II. Write Short notes on : (10 x 5 = 50)
1. Pathogenesis of bronchial asthma.
2. Barrett esophagus.
3. Cholelithiasis.
4. Renal cell carcinoma.
5. Benign prostatic hypertrophy.
6. Gynaecomastia.
7. Cretinism.
8. Microscopic features of basal cell Carcinoma.
9. Osteoclastoma (giant cell tumor).
10. Retinoblastoma.

III. Short Answer Questions : (10 x 2 = 20)

1. What are the different stages of Pneumonia?
2. Enumerate four different types of Emphysema.
3. Two differences between Chrons disease and Ulcerative colitis.
4. Gross differences between benign and malignant ulcers of stomach.
5. Enumerate four different types of renal stones.
6. Microscopic features of leiomyoma.
7. Mention two important microscopic features of Hashimoto’s thyroiditis.
8. Enumerate two radiological features of osteosarcoma.
9. Features of diabetic retinopathy.
10. Different types of giant cells.
*******
[KU 543] FEBRUARY 2009 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. 20 years female H/o pain, swelling, tenderness over lower and of right femer since
3 months. Suddenly developed breathlessness during her treatment and died, clinical
autopsy conducted. Answer the following:
a) What is your diagnosis?
b) Mention two investigations to arrive at diagnosis?
c) Aetio pathogenesis of the lesion?
d) Gross and Microscopic picture of the lesion?
e) Mention two autopsy confirmed lesions leading to death?
2. Discuss Aetio-pathogenesis, Pathologic lesions, laboratory diagnosis and
complications of rheumatic heart disease?

II. Write Short notes on : (10 x 5 = 50)

1. Hamartomas.
2. Crescentic glomerulo nephritis.
3. Gross and Microscopic picture of semenoma testis.
4. Laboratory diagnosis of Hepatitis.
5. Phaeochromocytoma.
6. Gross and Microscopic picture of amoebic dysentery colon.
7. Pneumoconiosis.
8. Haemolytic – uremic syndrome.
9. Haemochromotosis.
10. APUD cell tumors (amine precussor uptake and decarboxylation).
III. Short Answer Questions : (10 x 2 = 20)
1. Exfoliative cytology.
2. Mention four pre-malignanl- lesions.
3. Gohn’s lesion.
4. Cerebro spinal fluid findings in pyogenic meningitis.
5. Mention four opportunistic infections in AIDS.
6. Cryptorchidism.
7. Analgesic nephropathy.
8. Mention four germ cell tumors.
9. Condyloma acuminata (warts).
10. 4 pathological effects of gall stones.

*******
[KV 543] AUGUST 2009 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Describe the etiopathogenesis, gross and microscopy of chronic pyelonephrits.
2. A 35 years, old man was admitted with history of painless cervical and axillary
lymphadenopathy. He had history of loss of weight, fever and night sweating and was
found to have cutaneous anergy. No hepatosplenomegaly.
a) What is your most probable diagnosis?
b) Give the classification of the condition.
c) Describe the morphology of any two types.

II. Write Short notes on : (10 x 5 = 50)

1. Etiology of hepatocellular carcinoma.
2. Crohn’s disease.
3. Cardio myopathy.
4. Phyllodes tumor.
5. Etiology of carcinoma of cervix.
6. Gout.
7. Astrocytoma.
8. Duchenne muscular dystrophy.
9. Cartilage – forming tumors.
10. Malignant melanoma.

III. Short Answer Questions : (10 x 2 = 20)

1. Osteogenic sarcoma.
2. Haemochromatosis.
3. Hashimoto’s thyroiditis.
4. Pheochromocytoma.
5. Endometriosis.
6. Gynecomastia.
7. Colloid goiter.
8. Cryptorchidism.
9. Enzymes in myocardial infarction.
10. Peutz-Jeghers syndrome.
*******
[KW 543] FEBRUARY 2010 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Define and classify bronchogenic carcinoma.
Discuss the aetiopathogenesis and morphology of various sub types.
2. A 50 years old man collapses suddenly while climbing the stairs with severe chest
pain and profuse sweating.
a) What is your clinical diagnosis?
b) Discuss the aetiopathogenesis of the condition.
c) What are the complications that may follow the condition?

II. Write Short notes on : (10 x 5 = 50)

1. Ghon’s complex.
2. Chronic pyelonephritis.
3. Morphology of chronic gastric ulcer.
4. Cirrhosis of the liver.
5. Cryptorchidism.
6. Papillary carcinoma thyroid.
7. Cervical intraepithelial neoplasia.
8. Dysgerminoma.
9. Hydatidiform mole.
10. Phaeochromo cytoma.

III. Short Answer Questions : (10 x 2 = 20)

1. The four features of Fallot’s tetralogy.
2. Four differences between Hodgkin’s and Non Hodgkin’s lymphomas.
3. Morphology of two types of hiatus hernia.
4. Four clinical features of carcinoid syndrome.
5. Morphology of amoebic liver abscess.
6. Four causes of nephrotic syndrome.
7. Two causes of granular contracted kidneys.
8. Differences between classic and spermatocytic seminomas.
9. CSF changes in pyogenic meningitis.
10. Radiologic appearances of osteosarcoma.

*******
[KX 543] AUGUST 2010 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. A 12 year old boy presented with fever, oliguria and high coloured urine.
He had sore throat three weeks back.
i) What is your probable diagnosis?
ii) Describe the etiopathogenesis of the condition
iii) What are the relevant investigations?
2. Define and classify cirrhosis of liver.
Describe the morphological features of most common type cirrhosis of liver.

II. Write Short notes on : (10 x 5 = 50)

1. Tumour markers.
2. Silicosis.
3. Complications of diabetic mellitus.
4. Cholelithiasis.
5. Wilm’s tumor.
6. Pyogenic osteomyelitis.
7. Aneurysms.
8. Surface epithelial tumors of ovary.
9. Viral pneumonia.
10. Gross and microscopy of colorectal carcinoma.

III. Short Answer Questions : (10 x 2 = 20)

1. Etiological factors for hepato cellular carcinoma.
2. Advanced glycation end products.
3. Pan acinar emphysema.
4. Alpha Feto Protein (AFP).
5. Microscopy of papillary carcinoma of thyroid.
6. Pilocytic astrocytoma.
7. Atheromatous plaque.
8. Wire - loop lesion.
9. Enumerate chondrogenic tumors.
10. Fallots’ Tetrology.
*******
[KY 543] FEBRUARY 2011 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. A 50 year old man with complains of severe chest pain and sweating.
a) What is the most possible diagnosis for this patient?
b) Enlist the risk factors and discuss in detail the etiopathogenesis and
complications of this disease.
c) Enlist the biochemical tests and their role in diagnosis of this disease.
2. Classify inflammatory bowel diseases. Discuss briefly the etiopathogenesis, gross and
microscopic morphology of Crohns Disease. Enlist the complications of Crohns Disease.
Enumerate the differences between Crohns disease and Ulcerative colitis.
II. Write Short notes on : (10 x 5 = 50)
1. Opportunistic lung infections in AIDS.
2. Renal changes in diabetes mellitus.
3. Metabolic cirrhosis.
4. Thyroditis.
5. Liposarcoma.
6. Working formulation classification of Non Hodgkins Lymphoma.
7. Pagets disease of bone.
8. Medulloblastoma.
9. Etiopathogenesis of carcinoma cervix.
10. Gauchers disease.
III. Short Answer Questions : (10 x 2 = 20)
1. Enlist four causes of acute Myocarditis.
2. Enumerate the four types of Emphysema.
3. Mention two microscopic intestinal changes in Malabsorption syndrome.
4. Mention two differences between Nephrotic and Nephritic syndromes.
5. Enlist four microscopic features in Papillary carcinoma of thyroid.
6. Mention four features of Addisons disease.
7. Mention two major causes of Osteonecrosis.
8. Enlist two characteristic features of Mycosis Fungoides.
9. Mention two histological features of Dysgerminoma.
10. Mention four common tumours of Salivary gland.

*******
[KZ 543] AUGUST 2011 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper IV – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. Thirteen year old female child had massive edema with puffiness of face with
decreased urine output.
a. What is the most probable diagnosis ?
b. What can be the most probable renal pathology in this child ?
c. Write in detail about minimal change disease.
2. Classify neoplasms of thyroid. Write in detail about papillary carcinoma of Thyroid.

II. Write Short notes on : (10 x 5 = 50)

1. Consequences of atherosclerotic disease.
2. Write about asbestos related diseases and their pathogenesis
3. Pathogenesis and morphology of gastric carcinoma.
4. Write about benign neoplasms of liver.
5. Minimal change nephropathy.
6. Mention the malignant tumors of endometrium. Write a note about malignant
mixed mullerian tumor.
7. Mention the stromal tumors of breast. Write about Phyllodes tumor.
8. Write about Phaeochromocytoma.
9. Osteomyelitis.
10. Diabetic Nephropathy.

III. Short Answer Questions : (10 x 2 = 20)

1. Mention the three types of cardiomyopathy.
2. Classify Thyroiditis.
3. Dermoid Cyst of Ovary.
4. Risk factors for gall stones.
5. Bronchopneumonia.
6. Benign tumors of blood vessels.
7. Tuberculous meningitis.
8. Cystic renal dysphasia.
9. Diabetic macro vascular disease.
10. Chondroblastoma.
*******
[LA 543] FEBRUARY 2012 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper II – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions in the same order.
Draw Suitable diagrams wherever necessary
I. Elaborate on :
1. Classify ovarian neoplasms.
Discuss in detail the molecular pathogenesis and morphology of serous tumours.
(10 x 1 = 10)
2. 44 year old nulliparous women presented with hard, fixed non tender mass of about
6x4x4 cm in the upper outer quadrant of right breast with axilary lymphadenopathy.
a. What is your probably diagnosis.
b. Discuss in detail the prognostic & predictive factors of your diagnosis. (5 x 1 = 5)

II. Write notes on : (10 x 1.5 = 15)

1. Morphology of meningiomas.
2. Giant cell tumour.
3. Pathogenesis of basal cell carcinoma
4. Cholelithiasis.
5. Morphology of Acute Pancreatitis.
6. Vegetations of heart.
7. Paragangliomas.
8. Clear cell carcinoma – Kidney.
9. Morphology of ulcerative colitis.
10. Lab investigations of Acute myocardial infarction

III. Short Answers on : (10 x 1 = 10)

1. Mallory bodies.
2. Aschoff bodies.
3. Morphology of cardiac myxoma.
4. Ferruginous bodies.
5. Sarcoid granuloma.
6. Superior vena caval syndrome.
7. Potts spine.
8. Morphologic hall mark of Whipple disease.
9. Gross appearance of mature cystic teratoma.
10. Morphologic Features of papillary carcinoma – Thyroid.

*******
[LB 543] AUGUST 2012 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Paper II – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: Pages Time Marks
(Max.) (Max.) (Max.)
1. Etiopathogenesis, Pathology and Clinical Features of
Rheumatic Heart Disease. 16 30 10
2. 8 Yr Old boy with old scar of scabies skin lesion, with
history of Haematuria, Oliguria and Puffiness of face.
(a) What is your probable diagnosis.
(b) Etiopathogeneisis and laboratory investigations. 8 20 5

II. Write notes on:

1. Primary Pulmonary TB. 3 8 1.5
2. Chronic active Viral hepatitis. 3 8 1.5
3. Pilocytic astrocytoma. 3 8 1.5
4. Brenner Tumor. 3 8 1.5
5. Hashimoto’s Thyroiditis. 3 8 1.5
6. Ulcerative Colitis. 3 8 1.5
7. Bowen’s Disease of skin. 3 8 1.5
8. Osteoclastoma. 3 8 1.5
9. Phylloides tumor. 3 8 1.5
10. Oat cell Carcinoma of lung. 3 8 1.5

III. Short answers on:

1. Barrett esophagus. 2 5 1
2. Trisomy 18. 2 5 1
3. Aschof bodies. 2 5 1
4. Russel bodies. 2 5 1
5. Ghons foci. 2 5 1
6. Psammoma Bodies. 2 5 1
7. Call – Exner Bodies. 2 5 1
8. Monkeberg’s medial sclerosis. 2 5 1
9. 2 Malignant tumors of salivary gland. 2 5 1
10. Flexner Wintersteiner rosettes and Fleurettes. 2 5 1

*******
[LC 543] FEBRUARY 2013 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Paper II – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : 180 Minutes Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 15 = 30)
1. Tumors of liver – classification, Etiopathogenesis and prognosis.
2. 50 Yr old Male with painless firm Testicular swelling, with loss of testicular
sensation.
(a) What is your probable Diagnosis.
(b) Discuss classification and Etiopathogenesis.

II. Write notes on : (10 x 5 = 50)

1. Krukenberg tumour.
2. CROHN’S disease Morphology.
3. Dilated Cardio myopathy – Morphology and complications.
4. Neuroblastoma – Clinical features and Pathology.
5. Wilms tumour – Pathology.
6. Osteochondroma – Gross features.
7. Lobar pneumonia – Pathology.
8. Bowen’s Disease – Pathology.
9. Lannec’s cirrhosis – Morphology.
10. Cholelithiasis – Different types.

III. Short Answers on: (10 x 2 = 20)

1. Hurthle cell.
2. Blue Nevus.
3. Comedo carcinoma breast.
4. Weibel palade bodies.
5. Bridging necrosis – liver.
6. Coble stone appearance.
7. Dystrophic calcification – any 2 conditions.
8. Libman – Sacks endocarditis.
9. Oslers node.
10. Byssinosis.

*******
[LD 543] AUGUST 2013 Sub. Code : 4064

SECOND M.B.B.S. DEGREE EXAMINATION

Paper VI – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. 47 yrs old male presented with acute onset of dyspnea, profuse sweating and chest
pain radiating to the left shoulder. Lab investigation revealed elevated troponin – T.
What is your diagnosis, pathogenesis and morphology of the condition?
2. Classify ovarian neoplasms. Add a note on germ cell tumours.

II. Write notes on: (10 x 1.5 = 15)

1. Ulcerative colitis.
2. Rapid Progressive GlomeruloNephritis.
3. Morphology of bronchiectasis.
4. Prognostic and predictive factors for carcinoma breast.
5. Risk factors for gallstones.
6. Osteoclastoma.
7. Prion disease.
8. Basal cell carcinoma.
9. Pheochromocytoma.
10. Fibroadenoma – breast

III. Short Answers on: (10 x 1 = 10)

1. Aschoff bodies.
2. Mention 2 conditions of hereditary unconjugated hyperbilirubinemia.
3. Reid’s index.
4. Mention the histopathological features of endometriosis.
5. Mention 2 causes of acute pancreatitis.
6. Ground glass hepatocytes.
7. Struma ovarii.
8. Types of emphysema.
9. Cor pulmonale
10. Neoplasms of thyroid.

*******
[LE 543] FEBRUARY 2014 Sub. Code: 4064

SECOND YEAR MBBS DEGREE EXAMINATION

Paper VI – SYSTEMIC PATHOLOGY
Q. P. Code: 524064
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. A sixty year old male presented with anaemia, loss of weight, persistent abdominal
pain, abdominal distension and vomiting. Upper GI endoscopy and biopsy done.
a. What is the probable diagnosis?
b. Discuss the etiopathogenesis and morphology of the disease.
2. Enumerate the risk factors for atherosclerosis.
Discuss briefly the pathogenesis and morphology of atheroma.

II. Write Notes on: (10 x 1.5 = 15)

1. Hashimoto’s Thytoiditis.
2. Emphysema
3. Hydatidiform mole
4. Cystosarcoma Phylloides.
5. Ewing’s sarcoma
6. Pleomorphic adenoma of the salivary gland
7. Cervical intraepithelial neoplasia
8. Alcoholic liver disease
9. Pyogenic meningitis
10. Diabetic nephropathy

III. Short Answers on: (10 x 1 = 10)

1. Negri bodies
2. Prolactinoma
3. Adenomyosis
4. Spermatocytic seminoma
5. Causes of acute tubular necrosis
6. Schiller Duval bodies
7. Sites of peptic ulcer disease
8. Complications of myocardial infarction
9. Pannus
10. Paget disease of nipple

*******
[LF 543] AUGUST 2014 Sub. Code: 4064

SECOND YEAR M.B.B.S DEGREE EXAMINATION

Paper VI – SYSTEMIC PATHOLOGY
Q. P. Code: 524064
Time: Three Hours Maximum: 40 Marks
Answer ALL questions in the same order.
I. Elaborate on: (2 x 7.5 = 15)
1. a) 65/M presented with bleeding PR. Colonoscopy revealed a hard mass in
rectosigmoid. What is your diagnosis?
b) Discuss the various neoplasms arising in rectosigmoid, in detail about
morphological types and staging system.
2. Discuss the etiopathogenesis of viral hepatitis and in detail about serological
evaluation.

II. Write Notes on: (10 x 1.5 = 15)

1. Carcinoid syndrome
2. Mesothelioma
3. Granulosa cell tumour
4. Malignant salivary gland tumours
5. Granular cell tumour
6. Adamantinoma jaw
7. Xanthogranulomatous pyelonephritis
8. Cholangiocarcinoma
9. Thyroglossal duct cyst
10. Rhabdomyosarcoma.

III. Short Answers on: (10 x 1 = 10)

1. Chronic gastritis
2. Grading of urothelial malignancy
3. Cruetzfeldt Jakob disease
4. Stages of consolidation lung
5. Nasopharyngeal carcinoma
6. Actinomycosis
7. Sites of ectopic gestation
8. Chondroblastoma
9. Acoustic schwannoma
10. Mention sites of choriocarcinoma.

*******
[LG 543] FEBRUARY 2015 Sub.Code : 4064

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER VI – SYSTEMIC PATHOLOGY

Q.P. Code: 524064

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Define Diabetes Mellitus. What are the types? Describe the Pathophysiology,
morphology and complications of Diabetes Mellitus.

II. Write notes on: (4 x 5 = 20)

1. Biliary Cirrhosis
2. Pathogenesis of essential hypertension
3. Polycystic kidney disease.
4. Gall stones

III. Short answers on: (5 x 2 = 10)

1. Good pasture syndrome

2. Aschoff body
3. Cervical Intraepithelial Neoplasia
4. Henoch Schonlein Purpura
5. Cartilage forming bone tumors

********
[LH 543] AUGUST 2015 Sub. Code: 4064

SECOND M.B.B.S. DEGREE EXAMINATION

PAPER VI – SYSTEMIC PATHOLOGY
Q.P. Code: 524064
Time : Three Hours Maximum : 40 marks
Answer ALL questions
I. Elaborate: (1 x 10 = 10)
1. 50 years / Male admitted in emergency care with chest pain, profuse sweating and
Rapid pulse. What is your diagnosis? Describe the Etiopathogenesis, Morphology
and Complications of the above mentioned disease.

II. Write notes on : (4 x 5 = 20)

1. Crescentic Glomerulonephritis.

2. H.Pylori gastritis.

3. Sex cord stromal tumors of ovary.

4. Diabetic Microangiopathy.

III. Short answers on : (5 x 2 = 10)

1. Takayasu arteritis.

2. Zollinger Ellison syndrome.

3. Familial Adenomatous Polyposis syndrome.

4. Pagets disease of breast.

5. Glioblastoma Multiforme.

*******
[LI 543] FEBRUARY 2016 Sub. Code: 4064

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER VI – SYSTEMIC PATHOLOGY
Q.P. Code : 524064
Time : Three Hours Maximum : 40 Marks
Answer ALL questions
I. Elaborate on: (1 x 10 = 10)
1. A 3yrs old child was hospitalized for the complaints of fever and passing smoky urine.
The child had recovered from sore throat a week ago. What is your diagnosis?
Describe the etiopathogenesis, morphology and laboratory findings of this condition.

II. Write notes on: (4 x 5 = 20)

1. Grave’s disease.

2. Cholelithiasis.

3. Atherosclerotic plaque.

4. Bronchiectasis.

III. Short answers on: (5 x 2 = 10)

1. Raynaud phenomenon.

2. Tophi.

3. Causes of hypersensitivity pneumonitis.

4. Name the Germ cell tumors of the ovary.

5. Linitis plastic.

*******
[LJ 543] AUGUST 2016 Sub. Code : 4064

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER VI – SYSTEMIC PATHOLOGY
Q. P. Code : 524064
Time : Three hours Maximum: 40 Marks
Answer ALL questions.
I. Elaborate on : (1 x 10 = 10)
1. Describe the etiology, pathogenesis and morphology of infective endocarditis.
Write a note on non infected vegetations.

II. Write notes on: (4 x 5 = 20)

1. Rheumatic fever.

2. Pneumoconiosis.

3. Cystic lesions of kidney.

4. Prognostic and predictive factors of breast cancer.

III. Short answers on: (5 x 2 = 10)

1. Menetrier’s disease.

2. Condyloma acuminata.

3. Secondary hyperparathyroidism.

4. Classification of gestational trophoblastic diseases.

5. Microalbuminuria.

*******
[LK 543] FEBRUARY 2017 Sub.Code : 5066

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER VI – PATHOLOGY–II (SYSTEMIC PATHOLOGY)

Q.P. Code: 525066

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. 75 year male presented with dyspnea and sweating of sudden onset. He is a known
hypertensive and diabetic for 15 years. On examination he has weak pulse. What is
the diagnosis? Write about pathogenesis of the above disorder. Write in detail
about the morphological changes that occur.

II. Write notes on: (4 x 5 = 20)

1. Pathogenesis and morphology of silicosis.

2. Pathology, morphology and clinical features of Hirschsprung’s disease.
3. Risk factors and types of carcinoma breast.
4. Write about the pathogenesis and complication of diabetes mellitus.

III. Short answers on: (5 x 2 = 10)

1. Write briefly on types of hyperparathyroidism.

2. Morphology of alcoholic liver disease.
3. Mention four microscopic features of chronic pyelonephritis.
4. Define and write about sites involved in endometriosis.
5. Histological features of giant cell tumor of bone.

*********
[LL 543] AUGUST 2017 Sub.Code : 5066

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER VI – PATHOLOGY–II (SYSTEMIC PATHOLOGY)

Q.P. Code: 525066

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify ovarian neoplasms. Discuss in detail about surface epithelial tumors.

II. Write notes on: (4 x 5 = 20)

1. Aneurysm.
2. Pneumoconiosis.
3. Nephrotic syndrome.
4. Meningioma.

III. Short answers on: (5 x 2 = 10)

1. Enumerate the four main types of renal calculi.

2. Stages of lobar pneumonia.
3. Hashimoto thyroiditis.
4. List four etiological factors associated with squamous cell carcinoma of oral
cavity.
5. Etiological factors in acute pancreatitis.

*********