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Post-hydration:
Sodium Chloride 0.9% 1000mls with 20 mmol KCL and 2g MgSO4 over 2
hours
Note: Patients with low Magnesium levels (<0.7 mmol/l) should have an
additional 2g magnesium sulphate added to the pre-hydration bag
Frequency Weekly for a maximum of 6 weeks during radical radiotherapy
Extravasation Exfoliant (Group 4)
Premedication Pre-hydration as above
Emetogenicity This regimen has moderate-high emetogenic potential – refer to local
protocol
Additional If magnesium levels are consistently low, consider supplementation with
recommended oral magnesium glycerophosphate [Note: unlicensed product] 24 mmol
supportive Mg2+ per day in divided doses.
medication
Pre-treatment FBC Baseline – results valid for 14 days
evaluation U+E Baseline – results valid for 14 days
LFT Baseline – results valid for 14 days
Oncologist, BHOC
Matthew Beasley DN: cn=Matthew Beasley, o, ou, email=james.
carr@aswcs.nhs.uk, c=GB
Date: 2012.07.20 11:36:29 +01'00'
Document reviewed by
Version number
Summary of changes Version 1.1.b: Wording of administration section amended to improve clarity
1.2.b: Amended July 2012 to included option of Mannitol 10%