Cardiac Assist Devices (CAD) Global Market

–Forecast to 2024

Cardiac Assist Devices (CAD) Global Market estimated to be worth $4,255.5

million by 2024

IQ4I Research & Consultancy published a new report on “Cardiac Assist Devices
Global Market – Forecast To 2024” This report analyzes and studies the overall market,
major Drivers & Opportunities, Restraints & Threats in North America, Europe, Asia-Pacific
and Rest of the World.

IQ4I’s Report Contains 96 market data tables and 109 figures spread through 372
pages and an exhaustive TOC on “Cardiac Assist Devices Global Market”, [Product
{(Ventricular Assist Devices (Left Ventricular Assist Devices (LVAD), Right Ventricular Assist
Devices (RVAD) and Biventricular Assist Devices (Bi-VAD)), Total Artificial Heart (TAH) and
Intra-Aortic Balloon Pump (IABP)}; Implant type (Extracorporeal CAD, Intracorporeal CAD,
Percutaneous CAD); Pump type {(Pulsatile flow pump, Continuous flow pump (Axial flow
pump, Centrifugal pump)}; Patient type (Pediatric CAD, Adult CAD); Application (Bridge to
Transplant (BTT), Bridge to Destination (BTD), Bridge to Recovery (BTR); End-User
(Hospital, Academics & Research Institutes and Other End-User); REGION (North America,
Europe, Asia-Pacific and Rest of the World)]

Cardiac assist devices (CAD) are mechanical circulatory support devices used to treat end
stage heart failure, refractory angina pectoris, post-cardiopulmonary bypass shock,
myocardial infarction, myocarditis, etc. Heart failure is a chronic disease that occurs when
degeneration of the heart muscle reduces the pumping power of the heart, causing the heart
to become too weak to pump blood at a level sufficient to meet the body's demands. The
condition can be caused by arterial and valvular diseases or a cardiomyopathy. Other
conditions, such as high blood pressure or diabetes, also can lead to Heart failure. Cardiac
assist devices are majorly used for heart failure. The cardiac assist devices are classified
into three types i.e. Ventricular Assist Devices (VAD), Total Artificial Heart (TAH) and Intra-
Aortic Balloon Pump (IABP). Ventricular assist device (VAD) are mechanical pumps
designed to support one or two ventricles of the failing heart and depending on the
supported ventricle, the devices are classified as left (LVAD) to assist left ventricle, right
(RVAD) for right ventricular support, or both heart ventricles is replaced by Bi-Ventricular
Assist devices (BiVAD). The Total artificial heart is a mechanical circulatory assist device for
persons with biventricular heart failure and heart transplant candidates. The TAH replaces
both native ventricles and all four chambers of the heart, thereby eliminating the symptoms
of cardiac insufficiency or heart failure. Intra-aortic balloon pump (IABP) or counter pulsation
circulatory assist device is placed in aorta to help the heart to pump more blood by reducing
the workload on the heart and improves the function of the left ventricle as this is the

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Cardiac Assist Devices (CAD) Global Market

–Forecast to 2024

chamber that pumps blood into the aorta. IABP is used in conditions such as acute mitral
valve regurgitation or severe heart failure, left ventricular failure, unstable angina, etc. It is
also used during preoperative, intraoperative or postoperative cardiac surgeries.

According to IQ4I Analysis, Cardiac assist devices global market is expected to grow at a
double digit CAGR to reach $4,255.5 million by 2024. Increasing incidence of heart failure,
increase in the prevalence of cardiovascular disorders due to rise in aging population,
shortage of heart donors, the rise in the number of clinical studies performed, and
technological advancements are some of the drivers of the market. A vast number of
pipeline products, growing healthcare budgetary allocation and increasing funding for CAD
research are some of the growth opportunities available in the market. However, adverse
events and complication with the implantations of CAD, lack of skilled and trained
professionals, the high cost of CAD devices (i.e. TAH and VAD) are some of the restraints of
the market. Stringent regulatory requirements for the product approval and availability of
alternate products are some of the threats to the CAD market.

Among the various CAD products, VAD held the highest share in 2017 and is expected to
grow at a mid double digit CAGR from 2017 to 2024. CAD market by implant type is
dominated by Intracorporeal CAD and held largest share in 2017 and is expected to grow at
a double digit CAGR from 2017 to 2024. Percutaneous CAD segment is the fastest growing
market and is expected to grow with a high double digit CAGR from 2017 to 2024. Abiomed,
U.S. based medical device company has developed world’s smallest catheter based
percutaneous heart pump that provides hemodynamic support to the heart. Abiomed is a
leader in percutaneous CAD market. Abiomed Impella heart pump (Impella series - Impella
2.5, Impella 5.0, Impella CP, and Impella RP) is FDA approved and presently is one of the
factors for driving Percutaneous CAD market. Upcoming technological development in
percutaneous pump like CardioBridge short term intra-aortic percutaneous circulatory
support device will boost the percutaneous CAD market in future.

In pump type, the continuous flow pump segment accounted the largest share in 2017 and is
projected to grow at a strong double digit CAGR from 2017 to 2024. In patient type, the adult
CAD segment accounted the largest share in 2017 and is projected to grow at a strong
CAGR from 2017 to 2024. Among the Cardiac assist devices applications, Bridge to
Recovery (BTR) held the largest share in 2017 and is expected to grow at a high double digit
CAGR from 2017 to 2024. Among End-users, the hospital segment accounted the largest
share in 2017 and is projected to grow at a strong CAGR from 2017 to 2024.

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Advanced and upcoming technologies like miniaturization of implantable cardiac assist

devices, wireless heart pump, advancement in blood flow technology in case of VAD and
TAH, minimally invasive technologies and medical device coatings will drive the Cardiac
assist devices market. VAD and TAH are getting miniaturized so that the devices are
suitable for wide range of patient’s group. For instance, the HeartWare Left Ventricular
Assist System (LVAS) from Medtronic is a third-generation continuous flow blood pump for
the treatment of advanced heart failure. It features a miniaturized centrifugal device, which is
small enough to be implanted above the diaphragm in all patients. Likewise, TAH is
miniaturized from 70 cc to 50 cc to treat smaller patients and is approved with CE mark.
Wireless technology is developed to power VADs which reduces the chances of infections
as the cables are not having an entrance point into the body. For instance, ReliantHeart,
Inc., and Dualis MedTech GmbH, a provider of wireless energy and charging technology,
entered into a partnership to implement a wireless, Transcutaneous Energy Transfer system
(TET) exclusively for the HeartAssist5 Ventricular Assist Device. Dualis plans to integrate its
wireless energy transfer technology MedBase with the HeartAssist5 VAD. Procyrion’s aortix
is a catheter based small and continuous flow heart pump for heart failure patients, designed
to help assist the heart muscle and boost localized blood flow, instead of operating in heart,
it is perched in the aorta. Procyrion’s aortix device is not yet commercially available and
requires regulatory approval from FDA. Full MagLev Flow technology is a rotor advancement
developed by Medtronic, this technology allows the device's rotor to be suspended by
magnetic forces rather than mechanical bearings and does not cause any damage to blood
cells. BiVACOR is developing centrifugal TAH and has approached Japanese researchers
who basically helped to refine the magnetic levitation system used in the development of
TAH. These advanced and upcoming technologies will boost the Cardiac assist devices
market.

The Cardiac Assist Device market is consolidated with top four players occupying largest
share of the market and remaining market is occupied by other players. The top players in
the market are Medtronic PLC, Abbott Laboratories, Getinge group and Abiomed, Inc. which
control the major share of the market, as these companies have a strong distribution
network, patents and acquisition strategy. For instance, Levotronix was acquired by
Thorotech Corporation, which was acquired by St.Jude medical which in turn is acquired by
Abbott Laboratories in January 2017. Similarly, World Heart Corporation was acquired by
Heart Ware International, which was in turn acquired by Medtronic in August 2016.

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Cardiac Assist Devices (CAD) Global Market

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The Cardiac assist devices global market based on geography is divided into North America,
Europe, Asia-Pacific and Rest of the world. North America region commanded the largest
revenue in 2017 and is expected to grow at a double digit CAGR from 2017 to 2024. A high
prevalence of cardiovascular diseases such as heart failure, cardiogenic shock, dilated
cardiomyopathy, ventricular insufficiency, valvular heart disease, congenital heart diseases
and growth in aging population and a shortage of heart donors led the market growth in this
region. However, Asia-Pacific is expected to grow at a strong double digit CAGR from 2017
to 2024 owing to the rapidly increasing aging population with high prevalence of
cardiovascular diseases, improving healthcare infrastructure and rise in healthcare spending
in the emerging countries, such as India and China.

Major players in Cardiac Assist Device market include Abbott laboratories (U.S.), Medtronic
(Ireland), Syncardia Systems, Inc. (U.S.), Teleflex Incorporated (U.S.), Zeon Corporation
(Japan), Getinge Group (Sweden), Berlin Herat GmbH (Germany), ReliantHeart, Inc. (U.S.),
Fresenius Medical Care AG & Co. KGaA Care (Germany) and Abiomed, Inc. (U.S.).

Some of the other companies operating in CAD global market include Jarvik Heart, Inc.
(U.S.), Evaheart, Inc. (U.S.), Tandemlife (U.S.), Procyrion (U.S.), Calon Cardio -Technology
Ltd (U.K.), CardioBridge GmbH (Germany), Cleveland Heart, Inc. (U.S.), CorWave (France),
BiVACOR, Inc. (U.S.), Carmat SA (France), FineHeart SARL (France), etc.

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Cardiac Assist Devices (CAD) Global Market

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Reasons for buying this report:

 Cardiac assist devices global market is expected to reach $4,255.5 million by 2024 at
a CAGR of 12.9%.
 Identification and analysis of the Cardiac assist devices market by identifying various
segments by products, implant type, pump type, patient type, application, end-user
and geography.
 Revenue forecast of Cardiac assist devices market and strategic analysis of each
segment with respect to segmental growth trends.
 Identification of major market trends, Porter's model, and factors driving and
restraining Cardiac assist devices market growth.
 Analysis of Cardiac assist devices global market by number of units and their
average selling prices.
 Revenue forecast of the Cardiac assist devices market with respect to North America
(U.S. and Others), Europe (Germany, France, U.K. and Others), Asia-Pacific (Japan,
China, India and Others) and Rest of the World (Brazil, Rest of Latin America and
Middle-East & Others) regions.
 Analysis of the opportunities for stakeholders by identifying the high-growth
segments of the market.
 Identification of key technology developments and innovations driving the market.
 Analysis of the market share, upcoming technologies, patent and supply chains of
the Cardiac assist devices market by major players.
 Profiles of major players in Cardiac assist devices market and analysis of their
product offerings, financial revenue, business strategies, SWOTs and market shares.

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Cardiac Assist Devices (CAD) Global Market

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FIGURE 1

CARDIAC ASSIST DEVICES GLOBAL MARKET SEGMENTATION

Cardiac Assist Devices Global Market

By Product By Implant By Pump By Patient By

By End-User By Region
Type Type Type Type Application
Paracorporeal Pulsatile Flow
VAD Pediatric CAD Bridge to NA
CAD Pump
Transplant Hospitals
LVAD Intracorporeal Continuous U.S.,
Adult CAD Bridge to
CAD Flow Pump Others
Destination Academics &
RVAD Percutaneous Research
CAD Bridge to Institutes EU
Recovery
Bi-VAD Centrifugal Other End-
Axial Pump Germany, France,
Pump Users U.K., Others
TAH
APAC
IABP
Japan, China,
India, Others

RoW
Brazil, Rest of LA,
Middle East &
Others

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