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Datasheet of FF-10101

Detailed information:

http://www.sun-shinechem.com/Details/FF-10101/3725/1472797-69-5.html

USD250.0/50.0mg;
Price USD400.0/100.0mg
Please send your email to sales@sun-shinechem.com for other package.

FF-10101
Product Name

(S,E)-N-(1-((5-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidin-5-yl)pent-4-
Chemical Name
yn-1-yl)amino)-1-oxopropan-2-yl)-4-(dimethylamino)-N-methylbut-2-enamide

Synonyms FF-10101; FF10101;FF 10101

CAS No. 1472797-69-5 Catalog No 181244

Molecular Weight 530.66

Molecular Formula C29H38N8O2

Other information N/A

Items Specifications Results

Appearance Off-white solid Complies

HNMR 400MHz,d6-DMSO Complies


Analysis
HPLC 98.0% Complies

Storage condition Kept under dry and cool condition

The above substance has been tested according to In house Standards, and it
Conclusion
meets requirements.

No.8 Rd, The Great Wall Park, Dong’hu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com
FF-10101 is a FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2) inhibitor, with
potential antineoplastic activity.Upon administration of FLT3 inhibitor FF-10101 succinate
(FF-10101-01), FF-10101 irreversibly binds to and inhibits the activity of FLT3. This inhibits
Description
the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase
(RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid
leukemias. Check for active clinical trials using this agent. (NCI Thesaurus)

No.8 Rd, The Great Wall Park, Dong’hu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com

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