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Subtalar Joint Arthroereisis in the Management of Pediatric Flexible Flatfoot: A Critical Review of the
Literature
Stuart A. Metcalfe, Frank L. Bowling and Neil D. Reeves
Foot Ankle Int 2011 32: 1127
DOI: 10.3113/FAI.2011.1127

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FOOT & ANKLE INTERNATIONAL
Copyright  2011 by the American Orthopaedic Foot & Ankle Society
DOI: 10.3113/FAI.2011.1127

Subtalar Joint Arthroereisis in the Management of Pediatric Flexible Flatfoot:


A Critical Review of the Literature

Stuart A. Metcalfe, BSc(Hons); Frank L. Bowling, PhD; Neil D. Reeves, PhD


Manchester, UK

ABSTRACT Level of Evidence: II, Metanalysis

Background: Pediatric flexible flatfoot is a common deformity Key Words: Arthroereisis; Stent; Flexible Flatfoot
for which a small, but significant number undergo corrective
surgery. Arthroereisis is a technique for treating flexible flat-
INTRODUCTION
foot by means of inserting a prosthesis into the sinus tarsi.
The procedure divides opinion in respect of both its effective-
ness and safety. Methods: A database search up until 2010 was From infancy, the lower limb and foot are known to
used to find articles regarding arthroereisis in pediatric patients. undergo morphological and functional adaptation in order
We summarized the findings of this study. Results: Seventy- to meet the demands of the external environment. An initial
six studies were identified. Eight of the nine radiographic hyper-mobile unit with persistent low arch, the foot matures
parameters reported show significant improvement following achieving full adult form typically between 5 to 7 years.61,83
arthroereisis reflecting both increased static arch height and Ultimately, the healthy foot becomes a dynamically complex
joint congruency. Calcaneal inclination angle demonstrated the structure able to cope with the demands of locomotion.
least change with only small increases following arthroereisis.
Failure to develop a normal medial arch is common in chil-
Arthroereisis remains associated with a number of complica-
tions including sinus tarsi pain, device extrusion, and under-
dren and adolescents, and historically has been considered a
correction. Complication rates range between 4.8% and 18.6% pathological state.35 Traditional anthropometric measures of
with unplanned removal rates between 7.1% and 19.3% across the medial arch alone will capture all flat feet, yet fail to
all device types. Conclusion: Current evidence is limited to differentiate between those in which there is internal joint
consecutive case series or ad hoc case reports. Limited evidence incongruence on weightbearing, i.e., the pathological flat-
exists to suggest that devices may have a more complex mode foot and the flat but congruent foot. Uncertainty remains
of action than simple motion blocking or axis altering effects. regarding the short-, mid-, and long-term implications of
The interplay between osseous alignment and dynamic stability flat feet. Instability within the osseous and or soft tissue
within the foot may contribute to the effectiveness of this proce- restraining mechanisms of the foot will result in increased
dure. Although literature suggests patient satisfaction rates of workload of the antipronatory mechanisms (both in magni-
between 79% to 100%, qualitative outcome data based on
tude and temporally). Opinions remain polarized in respect of
disease specific, validated outcome tools may improve current
evidence and permit comparison of future study data.
the need to treat the pediatric flatfoot; some authors argue that
there is little if any need to intervene, claiming spontaneous
No benefits in any form have been received or will be received from a commercial resolution and lack of morbidity.1,4 – 6 Others suggest that flat
party related directly or indirectly to the subject of this article. feet are associated with functional aberration and increased
Corresponding Author: risk of injury.40,63 Further division exists with respect to
Stuart A. Metcalfe, BSc(Hons) treatment, some advocating conservative measures whilst
Manchester Metropolitan University
Institute for Biomedical Research into Human Movement and Health
others recommend “operative correction” of this enigmatic
John Dalton Building, condition.
Oxford Road Arthroereisis involves the placement of a “stent” or
Manchester, M1 5GD
United Kingdom
“implant” within the sinus tarsi and represents the least inva-
E-mail: footconsultant@gmail.com sive operative intervention. While its technical simplicity
and rapid recovery may be seen as advantageous, some
For information on pricings and availability of reprints, email reprints@datatrace.com
or call 410-494-4994, x232. authors claim this has led to inappropriate application.80 The
stent is believed to prevent abnormal rotations of the tarsus,

1127

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1128 METCALFE ET AL. Foot & Ankle International/Vol. 32, No. 12/December 2011

thus maintaining more normal anatomical relationships in neurological or connective tissue disease.25,79 This was
the dynamic setting. Alternative options necessitate more considered to have the potential to skew the complication
extensive surgery, increasing operative risk and postoperative data with respect to the role of subtalar joint arthroereisis in
recovery.23,42,54,74,94 Tarsal joint fusions and osteotomy also the treatment of pediatric flexible flatfoot. In summarizing
have potential for non union and growth plate disturbance. the available data within the present review, we considered
Though a well-established technique, there remains a paucity it appropriate, where possible, to distinguish outcomes and
of information surrounding the safety and effectiveness of complications by device type on the basis that variation
arthroereisis. As such there is a need to review the proce- in surgical technique and or the nature of the device may
dure’s safety and effectiveness. Through a critical review of influence clinical outcomes. The devices were classified
over 40 years of arthroereisis literature, the authors examine as set out in Table 1. Where study numbers have been
the operative and technological advancements pertaining to insufficient to separate data by device type, data has been
this technique, summarizing key outcome data with respect to pooled.
arthroereisis as well as identifying areas for future research.
Radiological outcomes
METHODS Radiological measures have long been applied as markers
of success in the management of flatfoot deformity, though
A database search was conducted [Medline from 1966 to their relationship to a patient’s perceived clinical status
2010; Cumulative Index to Nursing and Allied Health Liter- remains to be proven. Lanham first reported on changes
ature (Cinahl) from 1982 to 2010; and Embase from 1982 to in radiographic alignments following arthroereisis,45 after
2010] during the period of January 2010 to April 2010 using which most authors have included some form of radiolog-
the terms “arthroereisis,” “MBA,” “STA-peg,” “subtalar ical outcome measure.2,3,9,12,18,22,27,29,32,46,54,76 – 78,88,89,91,93
implant,” and “pediatric flatfoot.” Abstracts were reviewed to In reviewing the available published data, several limitations
identify which articles were included and excluded according become apparent. First, substantial variation exists in the
to the criteria defined below. As there was a general absence radiological parameters reported between studies. Second,
of well-controlled studies relating to arthroereisis, this review only a small number of studies declared their criteria and
included articles which met the following criteria: measurement procedures for the reported charted values.
The importance of measurement reliability or the statistical
1. The focus of the article was directly related to the significance of the observed measures was not universally
treatment of pediatric flexible flatfoot by means of reported.3,18,54 Additional confounding factors included vari-
arthroereisis and /or relating to complication or biome- ation in the timing of postoperative images, failure to disclose
chanical evaluation of arthroereisis, actual values, and lack of complete data sets in the reported
2. The article was published in a peer-reviewed journal, case series.12,91 With these limitations in mind, the authors
and have summarized the available data from 15 studies where
3. Published in the English language. actual values for radiological values are declared together
with the cohort numbers.1,12,18,22,27,32,46,48,54,66,76−78,86,89
RESULTS The n value for each radiological value summarized in
Table 2 will therefore vary due to the variation in reported
Seventy-six publications met the criteria for inclusion angles.
in this review. Several factors prevent pooling of data The results are consistent with a tendency, in static align-
for the purpose of conducting any type of statistical test. ment, toward increased arch height and great congruency
The literature on arthroereisis consists primarily of ad hoc within the tarsus and tarso-metatarsal alignments. No studies
case reports and retrospective case series reports (Level within this review correlated changes in radiological align-
III and IV evidence). Methodological variations included ments and patient reported outcome.
device type, inclusion criteria, surgical technique, application
of adjunctive procedures, and outcome measures. Some
series even report on adults and children within the same Table 1: Classification of Arthroereisis Devices
study, or report on varied surgical techniques within the
same series.20,29,98 Few studies applied validated clinical
Device Type Named Example
or patient reported outcome measures. Only one study
utilized a disease- and child-specific patient reported outcome Silicone non bespoke Swanson
measure.54 This study, however, compared post-intervention Silicone bespke Viladot
scores with aged matched controls rather than comparing Seated (within calcaneus) STA-peg Koning
individual scores pre- and postoperatively.54 In reporting Free floating bioresorbable Giannini
on outcomes, the authors have not included ad hoc case Free floating non resorbable MBA Kalix Hyprocure
reports or case series involving children with underlying
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Foot & Ankle International/Vol. 32, No. 12/December 2011 SUBTALAR JOINT ARTHROEREISIS 1129

Table 2: Radiological Charted Values (Degrees) Before and After Arthroereisis

Radiographic CI1,18,22,32, LT1st27,32, TD1,18,22,48,


12,32 22,66 22,66 46,48,78,87 46,54 54,77 – 78,87,90
Measure MCB TNJ LTCJ KITE22,54,66 CHt46 NHt90

Studies 2 2 2 8 4 9 3 1 1
Feet (n ) 115 108◦ 108 306 190 406 175 16 45
Preop Mean 145.5◦ 49.9◦ 40.45◦ 14.3◦ −16◦ 39.00◦ 28◦ 12 mm 16 mm
Postop Mean 132.5◦ 70.8◦ 33.65◦ 16.5◦ 0◦ 24.5◦ 20.0◦ 16 mm 24 mm
Change −13◦ +20.9◦ −6.8◦ +2.2◦ −16◦ −14.5◦ −8.0◦ +4 mm +8 mm

MCB, Moreau-Costa-Bartini; TNJCon, Talo navicular joint congruency; LTCJ, Lateral talo-calcaneal; CI, Calcaneal incliniation; LT1st, Lateral talo-first
metatarsal; TD, Talar declination; CHt, Cuboid height; NHt, Navicular height; N1, total number of feet in the one or more studies reporting on the
radiographic charted value.

Clinically related outcomes patients (16 feet), they demonstrated a mean improvement in
Between 1970 and 2004, ten studies have provided overall AOFAS scores of 19.4.46 While this outcome tool is not
rating of clinical outcomes in a total of 756 feet aged between validated specifically for use in the pediatric population,
36 and 240 months following subtalar arthroereisis using statisitcally significant differences (p < 0.05) were seen in
a range of device types specifically for the treatment of postoperative scores (Figure 1).
pediatric flexible flatfoot (Table 3).1,12,13,26,46,48,69,76,91

Complications Associated with Arthroereisis


Patient Satisfaction
Six studies have included some element of patient satisfac- Review of the literature reveals eight main categories of
tion though none utilized a validated foot specific outcome complication associated with arthroereisis devices. Table 5
tool for the pediatric population.1,22,42,46,86,89 Four studies summarizes theses complications where sufficient data was
provide overall estimates of patient satisfaction, though none available. In addition to the complications reported in
declare whether these are based on subject view or those of Table 3, several authors reported on transient symptoms,
the parents of the pediatric subjects. Some variation exists in including peroneal tendonitis, leg cramps, heel pain, and gait
the rating scales employed which is accounted for in Table 4 abnormalities, which have been excluded.22,30,48,91 Analysis
by inclusion of all categories described. In total, 118 patients of complications, in particular the application of regression
(212 feet) are included in estimates of overall patient satis- statistics to identify potentially important factors, has not
faction using non-validated outcome measures. been possible due to the poor quality of data. A number
To date, four studies have employed a validated foot report overall percentage rates rather than raw data. To maxi-
specific patient outcome tool, American Orthopaedic Foot mize the available data percentages, the total number of feet
and Ankle rating scale (AOFAS).25,46,53,92 Only one study, are given in Table 5. For clarity, the studies included against
however, met the stated inclusion criteria. Involving eight each data set are shown.

Table 3: Surgeon-Based Outcome Following Arthroereisis

Series¥ 176 292 31 413 548 687 726 812 946 1069
Device¥¥ S V SS V L ST GI GI K GI N/A
Cases (N1) 54 - 10 43 49 23 32 33 8 43
Feet (N2) 108 234 16 77 96 41 38 50 16 80
Excellent¥¥¥ 24.2 0 0 58.4 0 0 0 28 50 0 16.6
Good¥¥¥ 42.4 100 70 29.9 72.9 58.4 100 62 50 56.8 64.2
Fair¥¥¥ 27.4 0 20 11.7 19 36.6 0 4 0 30.3 14.9
Poor¥¥¥ 6 0 10 0 3 4.9 0 6 0 13 4.3

¥, Surgeon-based outcomes from ten studies (series 1 to 10) as cited. N1, number of cases in each study. N2, number of feet in each study.
¥¥ , Device types within each study (S, Silastic; V, Viladot; SS, Silastic sphere; L, Lundeen; ST, STA-peg; G, Giannini; K, Kalix).
¥¥¥ , Clinician-based assessment of the surgical result graded “excellent to poor.”

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1130 METCALFE ET AL. Foot & Ankle International/Vol. 32, No. 12/December 2011

Table 4: Summary of Subjective Outcome Data

Reported Series 11 286 322 442 590 646


Device Type SS ST ST C GI K
Patients (N1) 10 23 21 27 29 8
Feet (N2) 16 41 40 54 45 16
Age range (months) NR 84– 240 48– 192 48–132 74.5– 186 96– 168
Mean age (months) NR NR 120 96 118 132
Mean followup (months) 54.5 32 36 144 36 31.4
% Would have operation again = “Yes” 90 85 85 63 NR NR
% Would have operation again = “No” 10 nr 0 18.5 NR NR
% Would have operation again = “Undecided” 0 nr 15 18.5 NR NR
SATISFACTION RESULTS
% Satisfied NR 90 NR 81.5 79 100%
% Reasonably satisfied NR NR NR 11.1 0 NR
% Moderately satisfied NR NR NR 7.4 0 NR
% Dissatisfied NR NR NR 0 21 NR

∗,SS, Silastic sphere; ST, STA-peg; C, Cone; G, Giannini; K, Kalix; NR, not reported. Six studies are represented in Table 4 reporting on subjective
outcomes with five device types.

the assumption being that with control of excessive foot


pronation, bony and soft tissue adaptation would manifest as
correction of the arch. With a followup of only 12 months this
was not substantiated, though this concept underpins biore-
sorbable devices.25,27 Lanham et al. reported on a sample of
11 patients (22 feet) from a series of 51 patients (102 feet).
Using the stem of a Swanson implant they noted a reduction
in talar declination and talocalcaneal angles.35 Similar results
were reported by Volger using the same type of device fitted
Fig. 1: Comparison of AOFAS scores following subtalar joint arthroereisis.
into a drill hole so as to minimize the risk of extrusion.93
Adaptation of existing silicone toe implants paved the way
DISCUSSION for a variety of purpose made devices.1,2,45,67,93 Addante et
al. reported on a single pediatric case of flexible flat feet using
Functional impact, operative morbidity and longer term a purpose made Silastic sphere (Sutter Biomedical Inc.).2
sequelae following joint fusion(s) have most likely prompted This technique involved a 7-cm incision with suturing of the
exploration of alternative approaches to the treatment device into the spring ligament. Resolution of symptoms and
of flexible flatfoot. Arthroereisis is defined as the “limitation improvement in three radiological alignments was reported
of exogenous joint motion without complete arthrodesis.”55 at 3 years postoperatively. In a retrospective review, Smith
Chambers described an operation to elevate the ante- & Rappaport reported on outcomes following Silastic plug
rior calcaneus, thus blocking abduction of the foot by arthroereisis in their series of 54 patients (108 feet) treated
interfering with the forward and downward sliding of for painful idiopathic flatfeet in children.76 All 20 patients
the talus.15 Subsequently, modifications were reported, the available for radiological review demonstrated improvement
last being an opening wedge osteotomy of the sustentac- in key radiographic alignments. Two required device removal
ulum tali.70 Technicality and associated complications with and one reported swelling suggestive of implant extrusion.
osseous techniques prompted exploration of Selection of silicone most likely reflected availability,
alternatives.8,11,14,15,28,31,34,47,70 Early pioneers of arthro- and a belief that it was biocompatible with good loading
ereisis sought to find a means by which patients might tolerance though no in vitro or in vivo testing was reported.
achieve preservation of joint movement with control of Viladot published the largest series of the time using a
hypermobility. purpose made “wine glass”-shaped Silastic implant.91 This
Results of a free-floating Siliastic arthroereisis device retrospective case series of 234 feet, in children 5 to 15 years
were first described in 1974.85 Subotnick highlighted the of age reported on a range of clinical, anthropometric and
need for any device to be mechanically stable for 2 years, radiological measures. Uniquely, the Viladot stent spanned
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Table 5: Complications in Association with Arthroereisis

Device Type

Non Bespoke
Silicone Silicone Bioresorbable Seated Free Floating

Studies 244,76 51,9,12,92,94 127 722,30,42,48,77 – 78,86 1012,18,26,32,46,54,66,69,


90,99
Reported
Study Period NR 1970– 95 NR 1974– 2002 1989– 2007
Patients (n ) 65 69 21 204 278
Feet (n ) 130 351 42 394 500
Age (mean, mean = NR mean = 144m94 mean = NR mean = 102m22,30,42,48,78 mean = 132.3m12,18,32,
46,54,66,69,90,99
range)
range = NR range = range = 96– 180m27 range = range = 48– 204m12,18,
Foot & Ankle International/Vol. 32, No. 12/December 2011

26,32,46,54,66,69,90,99
60– 180m9,13,92,94 36– 240m22,30,42,48,77 – 78,86
Followup mean = 24m76 mean = 30.8m1,9,94 mean = 48m27 mean = 56.8m22,42,78,86 mean = 36.2m12,18,32,46,
54,66,69,90
(mean, range)
range = 4–48m44 range = 3–168m1,9,13,94 range = NR range = range = 2.5– 72m12,18,26,
32,54,66,69,90,99
12– 192m22,30,42,77 – 78,86
Complications N = 244 N = 431,9,12,92,94 N = 227 N = 6122,30,42,48,77 – 78,86 N = 7312,18,26,32,46,54,66,
69,90,99
(n )
44 1,9,12,92,94 27 22,30,42,48,77 – 78,86
% Overall 9.1% 18.6% 4.8% 19% 14.9%12,18,26,32,46,54,66,69,
90,99
Complications
Removal Rates mean = 19.3%76 mean = 8%1,9,12,92,94 mean = 0%27 mean = 7.1%22,30,48, mean = 7.9%12,18,26,32,
77 – 78,87 46,54,69,90,99
(grand

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means, range)
range = NR range = 0–36.4%1,9,12, range = 0%27 range = 1.9– 20%22,30,48, range = 0– 15.8%12,18,26,

Copyright  2011 by the American Orthopaedic Foot & Ankle Society


92,94 77 – 78,87 32,46,54,66,69,90,99
76 1,9,12,92,94 27
Extrusion mean = 9% mean = 0.5% mean = 4.8% mean = 0.8%22,30,48,77 – 78,87 mean = 2.7%12,18,26,32,
46,54,69,90,99
1,9,12,92,94 22,30,48,
range = NR range = 0–2.6% range = NR range = 0– 3.7% range = 2.5– 22%12,18,26,
77 – 78,87 32,46,54,69,90,99
1,9,12,92,94 27 22,30,48,77 – 78,87
Sinus Tarsi Pain mean = NR mean = 7.3% mean = 4.8% mean = 9.6% mean = 7.4%12,18,26,32,
46,54,66,69,90,99
1,9,12,92,94
range = NR range = 0–36% range = NR range = range = 0– 38%12,18,26,
32,46,54,66,69,90,99
SUBTALAR JOINT ARTHROEREISIS

1.1– 45.5%22,30,48,77 – 78,87


1131
1132

Table 5: Continued

Device Type

Non Bespoke
METCALFE ET AL.

Silicone Silicone Bioresorbable Seated Free Floating

Synovitis mean = NR mean = NR mean = 0%27 mean = 0.3%22,30,48,77 – 78,87 mean = 0%12,18,26,32,
46,54,66,69,90

range = NR range = NR range = NR range = 0– 1.9% range = NR


22,30,48,77 – 78,87

Infection mean = 0%44,76 mean = 2.2%1,9,12,92,94 mean = 0%27 mean = 0.8%22,30,48,77 – 78,87 mean = 0%12,18,26,32,46,
54,66,69,90,99
(Superficial)
44,76 1,9,12,92,94 27 22,30,48,77 – 78,87
range = 0 range = 0–7.8% range = 0 range = 0 – 4.5 range = 012,18,26,32,46,
54,66,69,90,99
44,76 1,9,12,92,94 27 22,30,48,77 – 78,87
Infection (Deep) mean = 0% mean = 0.6% mean = 0% mean = 0.35% mean = 0%12,18,26,32,46,
54,66,69,90,99
44,76 1,9,12,92 27
range = 0 range = 0.2–6% range = 0 range = 0– 2.4% range = 012,18,26,32,46,54,
22,30,48,77 – 78,87 66,69,90,99
44,76 1,9,12,92,94 27 22,30,48,77 – 78,87
Under- mean = 0% mean = 0% mean = 0% mean = 10.5% mean = 15.4%12,18,26,32,
46,54,69,90,99
Correction
range = 044,76 range = 01,9,12,92,94 range = 027 range = 0– 34.1% range = 0– 93%12,18,26,
22,30,48,77 – 78,87 32,46,54,69,90,99
,76 1,9,12,92,94 27 22,30,48,77 – 78,87
Over-Correction mean = 1.5% mean = 0% mean = 0% mean = 0% mean = 0%
12,18,26,32,46,54,69,90,99

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1,9,12,92,94 27 22,30,48,77 – 78,87
range = NR range = 0 range = 0 range = 0 range = 0
12,18,26,32,46,54,69,90,99

Copyright  2011 by the American Orthopaedic Foot & Ankle Society


44,76 1,9,12,92,94 27 22,30,48,77 – 78,87
Peroneal Spasm mean = 0% mean = 0.1% mean = 0% mean = 0.6% mean = 0%
12,18,26,32,46,54,69,90,99
44,76 27
range = 0 range = 0–0.04 range = 0 range = 0– 0.25% range = 012,18,26,32,46,54,
1,9,12,92,94 22,30,48,77 – 78,87 69,90,99

The complications rates are not cumulative. For example, stent extrusion may have necessitated device removal, and therefore the reader is advised not to over-count the complications by adding
the columns. Not all studies reported on all parameters; therefore, relevant references for each data sets are shown. NR, Not reported.
Foot & Ankle International/Vol. 32, No. 12/December 2011
Foot & Ankle International/Vol. 32, No. 12/December 2011 SUBTALAR JOINT ARTHROEREISIS 1133

the entire width of the sinus tarsi requiring extensive dissec- and most comprehensive case series of the day. Applying
tion for placement. The stem-shaped design was considered clinician-based outcomes 78% of patients achieved a good
to reduce the risks of extrusion, a complication of sili- clinical outcome (reduced deformity and resolution of symp-
cone devices.1 – 2,45,76,85,93,96 Clinical improvement was seen toms). Two patients were noted to have flattening of the
in all cases with normalization of the footprint using the lateral talar process suggestive of implant bone contact
photopodogram in 56% and partial normalization in a further loading.48
43%.91 Carranza-Bencano et al. reported on a retrospective Intraosseous cyst formation has been reported following
series of 77 patients with 88% reporting either “excellent” STA-peg arthroereisis.62 Computerized tomography and
or “good” clinical outcomes.13 In stark contrast to many subsequent intra operative inspection revealed erosion of the
authors, Black et al., in a retrospective case series of 15 calcaneum at the implant interface together with cyst forma-
patients (22 feet), reported a 36% removal rate due to device tion within the talar neck. Micro motion, well known to
intolerance and poor success as determined by anthropo- induce osteolysis, was considered to underpin the compli-
metric, pressure, and radiographic analysis.1 – 2,13,45,67,76,85,91 cations and thus non cemented fitting of STA-peg devices
Between 1974 and the 1990’s, several key papers report on may be implicated in migration of particulate debris resulting
Silastic arthroereisis devices for the treatment of pediatric in local osteolysis.41 In 2001, Forg et al. reported on 21
flexible flatfoot. Whilst these reports lack a uniformity of patients (40 feet) aged 4 to 16 years with a mean followup
study design, evidence emerged to support the concept of of 3 years (range, 12 to 90 months).22 Six of seven subjec-
a non-biologic arthroereisis device paving the way for new tive parameters improved with 85% of the cohort stating
devices.1,13,19,29,45,67,76,85,91 they would “recommend” or “highly recommend” the proce-
First used in 1974 and reported in 1983, the STA-peg dure. Complications included three patients, one developing
represented the first purpose designed non silicone device.33 peroneal spasm following injury, the second with sinus tarsi
Fixed directly into the calcaneus, it was believed to alter pain, and a third case requiring implant removal attributed
the axis of the subtalar joint preventing excessive anterior to excess bone cement.
shift of the talus thus correcting heel valgus and eliminating Advance in arthroereisis design came with the introduction
excessive pronation.30,77 This first description retrospectively of cannulated cementless systems requiring minimal opera-
reported on 27 patients (53 feet) between 3 and 17 years tive assault. Purpose made implants with improved anatom-
of age. With a minimum followup of 3 (range, 3 to 9) ical configuration and ease of fitting saw a transition away
years, Smith’s paper represented the longest followup of from both the silicone and cemented devices. In their paper
the time. Typical of previous papers, outcome measures regarding the Valente procedure, Langford et al. showed that
remained clinician based with significant improvements in Valente employed polyethylene implants of varying sizes
key anthropometric (heel valgus and arch appearance) being which could be matched intra operatively to the patients
reported in over 95% of patients. Complications included clinical picture.43 Two cadaver studies have demonstrated
pain and swelling in three patients which spontaneously the relationship between device size and limitation of joint
resolved in two; the third patient required synovectomy to motion supporting clinical observations.17,38 Limitations of
relieve symptoms. A fourth patient fractured the inferior these studies include uniform loading and a failure to account
cortex of the calcaneum following a fall. Reduction of for muscle function during testing.71 – 72
mechanical integrity of the calcaneus and or alteration to Throughout the 1980’s to early 1990’s, numerous new
subtalar joint function, due to the STA-peg insertion may arthroereisis devices were reported. A retrospective review
or may not have played a role in this fracture. The device of 32 patients aged 7 to 13 years using a two-component
found widespread popularity into the 1990’s with over 15 device noted clinical improvement in all cases, though six
published papers reporting on STA-peg arthroereisis. A later patients required device removal and no radiographic data
review of 11 patients (20 feet) aged 3 to 17 years applying were included.26 Verheyden et al. provided a more detailed
similar clinician based outcome measures, noted improved analysis using the same device in patients aged 6 to 15 years
appearance of the feet in ten of the 11 patients.77 of age with painful flat feet.89 Of the 29 patients (45 feet), 14
Substantial age variation exists between studies, some underwent supplementary Kidner-type procedures. Results
including children as young as 2 years.29,56,84 – 85 First, inter- of this retrospective case series highlight the importance
vention prior to foot maturation might imply unnecessary of including both clinician and patient evaluations. While
treatment. Second, differentiation between natural resolution Giannini’s original report included only clinical outcomes,
and that owed to the intervention must be considered. Third, Verheyden et al. employed a patient satisfaction question-
skeletal immaturity complicates radiographic measurement naire in addition to the clinical and radiographic outcome
due to lack of osseous landmarks. measures. Eighty percent of their patients reported subjective
Lundeen modified the STA-peg device claiming improved satisfaction with the operative outcome, 21% were dissat-
biomechanical function.48 Reporting on 49 patients (96 feet) isfied. Using a single observer to minimize measurement
aged 3 to 19 (mean, 8) years and a mean followup of error, improvements in both navicular height and talar decli-
46 (range, 19 to 76) months, this represented the largest nation were reported. In contrast to Giannini’s technique,
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1134 METCALFE ET AL. Foot & Ankle International/Vol. 32, No. 12/December 2011

Verheyden removed the contents of the sinus tarsi cutting Oxford Child Foot Questionnaire represents one such tool
the interosseous ligament, which may have contributed to which could be universally applied in this setting.52 Adoption
the observed differences. of a disease specific and age validated tool would permit
Developed in the mid-1980’s Maxwell et al. reported on pooling of future published data.
the MBA device in 1999.49 This device claimed several Arthroereisis reports often include data on radiographic
design benefits over its predecessors. Titanium had by this alignments, comparing pre and postoperative alignments.
time, established a record of excellent biocompatibility. Vanderwilde et al. published normative data for a range
Varying sized implants (6 to 12 mm) and temporary sizers, of radiographic values in their study of 74 children aged
permitted intraoperative sizing with identical devices. Deep 6 to 74 months, though no measures of repeatability were
threads along the implant claimed to reduce implant extru- included.87 Repeatability of X-ray measurement is subject to
sion. Three grooves cut into the device body were claimed to both biological and technical error.10,33,59,64 In adults stan-
offer “shock absorption,” though this has not been demon- dardization has been shown to provide reproducible images.
strated in vivo.16 By the late 1990’s, arthroereisis devices Measurements taken from films is known to be subject to
shared many common features; cannulated application, intra significant intra and inter observer error.64 Additionally the
operative sizers, biocompatible materials and a range of production of a two-dimensional image to represent the three-
implant sizes. A further shift is seen with regard to age of dimensional foot has been shown to produce potential errors
application, with fewer reports of application in infants in when comparing X-ray with cadaver models.60 A further
today’s literature compared with the reports of the 1970’s and consideration is the effect of skeletal development which
1980’s. This more judicious approach allows natural skeletal may impact on radiographic measurement. Future studies
development and the opportunity of self-correction in young may consider reporting short- and long-term radiographic
children. changes. Despite these limitations, there is a notable trend
Of the four studies employing the AOFAS, only one study to suggest arthroereisis leads to an improvement in many of
met, in full, the inclusion criteria for this review.46 Giannini the key charted values54 though a number of authors have
et al. published the first retrospective case series using the failed to investigate for possible correlation between radio-
American Orthopaedic Foot & Ankle Scale (AOFAS) in graphic alignment and subjective evaluation.7,88,92 Cadaver
a pediatric population (mean, 14 years; range, 9 to 18 studies have demonstrated reduced load to the plantar liga-
years).25 Twelve patients (14 feet) underwent correction ments after simulated arthroereisis using a 6-mm wooden
of flatfoot associated with tarsal coalition. Mean AOFAS dowel in a simulated flatfoot model.6 Restoration of talar
scores increased from 29 to 90 in keeping with subjective declination may conversely be associated with reduced load
outcome ratings. Though not validated for the use in the to these restraining structures. Many authors have suggested
pediatric population, other authors have adopted the AOFAS application of arthroereisis whilst there is substantial growth
in their case series. Needleman reporting on the MBA potential within the foot to allow for adaptive recovery of soft
device used to treat adult flexible flatfoot in 23 adults (n = 28 tissues. Coupled with the potential for secondary deformity,
feet) demonstrated similar outcomes with mean scores of in particular fixed forefoot inversion as a result of patholog-
52 preoperatively, rising to 87 postoperatively.53 Similar ical stance phase heel eversion, one can begin to make a case
improvements were reported in the single study to meet our for a theoretical optimum age.
review criteria.46 A statistically significant (p < 0.005) mean In July 2009, the UK’s National Institute of Clinical
improvement in AOFAS scores was seen in the cohort of Excellence (NICE) published interim guidance regarding
eight patients (16 feet) at a mean followup of 31.4 months. arthroereisis (Interventional procedure guidance 305),
Inclusion of patient based outcome measures have become concluding that there is currently insufficient evidence with
more widely adopted since their application by Smith and the respect to the safety and efficacy of this procedure. Within
Rappaport in 1983.76 However, despite improved reliability their published summary of procedure safety they grouped
of validated disease and age-specific tools, only Nelson all devices, even those no longer in common usage. Compli-
employed a validated tool specific for pediatric populations.54 cations of all devices are grouped, even those devices no
Although significant improvements in scores are reported, it longer used. Improved transparency with regard to outcome
must be noted that baseline data was obtained from published data will minimize misinformation provided to patients and
age matched norms and not from the treatment cohort. While clinicians alike. Several specific areas are worthy of further
application of disease-specific patient outcome tools is to discussion.
be encouraged, it is essential that such tools are validated.
This is particularly important for the pediatric population Safety of arthroereisis
where complexity, language, and design may limit both Critics of arthroereisis often cite complications without
criterion validity, responsiveness, and longitudinal validity of due consideration of the risks of alternative interventions.
the scales.97 Incorporation of both objective and subjective Complications must be contextualized to be of value in
outcome data is essential. Intuitively, one might assume a the clinical decision making process. Silicone devices, once
strong correlation though this may not be the reality.89 The in common use, have been superseded by titanium and
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Foot & Ankle International/Vol. 32, No. 12/December 2011 SUBTALAR JOINT ARTHROEREISIS 1135

polyethylene.1 – 2,9,67,76,91,93 Advances in instrumentation, (10%) required device removal because of implant degra-
improved device biocompatibility and minimally invasive dation related soft tissue swelling associated with pain.
techniques have mitigated some of the historical compli- While the biochemical aspects of the degradation process
cations. Avoidance of polymethylmethacrylate overcomes are the same for all patients, not all patients develop pain
complications associated with thermal necrosis, inhibition and swelling. Biological load related to implant size and
of antibacterial activity and cement-induced hepatitis.62 degradative capacity probably play a role, that is to say,
Whilst polyethylene and titanium are considered “biocom- greater volume of material impose greater demands. Reduced
patible” by the operative community, no material is truly vascularity and tissue coverage may limit cellular capacity
“biocompatible.”37 In vitro testing provides insight into the for implant breakdown. Application of bioresorbable mate-
wear characteristics of materials and thus potential dura- rials for arthroereisis requires confirmation that the device
bility. However, differences may exist in vivo. Polyethy- is necessary for a limited time frame, consistent with the
lene has been shown to undergo dynamic changes in vivo characteristics of the materials employed.
associated with reduced mechanical performance. Production Maintenance of correction following implant removal,
of osteolytic mediators exposed to titanium wear particu- albeit with short-term followup, has been previously
lates have been reported.37 These cellular mechanisms may reported.27,65,68 Arthroereisis has been claimed to reduce
underpin a number of the observed complications associ- stress to peri talar structures, promoting restoration of
ated with arthroereisis including pain, edema, and bone function and recovery from attenuation. Using a three-
osteolysis. Modern devices are typically made of stain- dimensional multi-segment cadaver model, Arangio assessed
less steel, polyethylene, titanium, combined construction joint moments in normal, simulated flat, and flatfoot with
or bioresorbable.21,27,49,65,92 Loading stresses may play an arthroereisis. Insertion of a simulated arthroereisis device
important part in the pattern and degree of device wear. In (6-mm wooden dowel) decreased pronatory moment arms
a cadaver-based model undergoing cyclical loading, Schon within the medial column.6 The observed improvements
reports contact loading of as little as 1.3 N at the bone device being similar to a similar simulation examining the impact
interface though detailed methodology is not disclosed.68 of medial calcaneal displacement osteotomy.68 The correc-
Confirmation of loads between the tarsus and implant is tive effect of 6-mm wooden dowel may be less than that of
important for future device design and prediction of stress actual arthroereisis device. A relationship between implant
related complications. size and increased corrective effect has been previously
Tissue discoloration due to titanium deposition has been demonstrated.17 Changes in the frontal plane position of the
reported around most types of implants.95 Behaviour of subtalar joint alter the moment arm of the medial and lateral
materials, including biocompatibility, is influenced by its heads of gastrocnemius, progression toward calcaneal ever-
specific application. Both arthroereisis material and design sion in stance produces an increasingly pronatory pull by
will impact on mechanical performance. The MBA device gastrocnemius.
with sharp titanium flutes differs from the smoother profiles All of the modern-day arthroereisis devices adopt near-
of other device designs such as the Kalix and Hyprocure identical techniques and thus infection rates should reflect
(Figure 2). those of similar clean elective interventions. The impact
The first purpose designed bioresorbable device was of sinus tarsi evacuation and inter osseous release require
reported in 2001.27 Others have adapted bioresorbable further investigation to determine their contribution to
devices (screws) as arthroereisis devices.65 Application of adverse outcomes. Literature reveals no consensus in regard
absorbable screws cut down and lodged within the sinus to cutting of the sinus tarsi ligaments. Some authors
tarsi is reminiscent of historical techniques.44 In the single consider it a critical component of the procedure.43,76 Subot-
published case series using a bioresorbable device (poly L- nick describes releasing the inter osseous ligament in all
lactic acid) involving 21 patients (42 feet), two patients cases.84 – 85 Smith and Rappaport suggest release of the

Fig. 2: Example of different arthroereisis devices.


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1136 METCALFE ET AL. Foot & Ankle International/Vol. 32, No. 12/December 2011

ligament is associated with an observed supination of the varus are reported by a number of authors, though few if any
calcaneus.76 Tompkins et al. highlight the need to release explanations are offered. Smith and Westlin observed that in
portions of both the cervical and interossseous ligaments to the face of ankle valgus high rates of complications could
gain adequate operative exposure to correctly fit the device.68 be expected and this should be included in the preoperative
Nelson et al. advocated cutting of the interosseous liga- work-up.75
ment in all 37 (67 feet) pediatric patients treated by MBA
arthroereisis.54 Others stipulate retention of this structure, CONCLUSION
suggesting that evacuation of the sinus tarsi and cutting
of the interosseous ligament might underpin the differences Pediatric flexible flatfoot remains a poorly defined pathology
in outcomes.53 Zaret and Myerson suggest cutting of the with little agreement regarding treatment.39,40,81,82 Arthroereisis
interosseous ligament is unnecessary, causing instability of represents a minimally invasive procedure capable of correcting
the subtalar joint.98 The significance of inter osseous release flexible flatfoot through a combination of static, dynamic
with respect to arthroereisis success or failure remains to be and proprioceptive mechanisms. As a treatment option it
elucidated. continues to polarize opinion. A focus on internal joint
congruency rather than simple anthropometric measures may
Reversibility
sharpen our understanding. There is a growing body of
Arthroereisis has the potential for “reversibility.”43,92
evidence linking abnormalities in joint malalignment to the
Compared to alternative operative procedures, the operative
development of osteoarthrosis.4,36,58,90 More recent obser-
insult is small and recovery more speedy when performed
vational studies have demonstrated a greater incidence of
in isolation.98 Whilst there is no specific published data
osteoarthrosis in flat feet compared with controls.50 For
examining outcomes of failed arthroereisis leading to device
the foreseeable, arthroereisis remains a popular intervention
removal, some encouraging insight is possible. Vedantam
with foot and ankle surgeons. While the precise mecha-
et al. removed five STA-peg implants (3.5%) because of
nism by which arthroereisis improves foot alignment remains
persistent pain.88 Symptoms resolved in all cases following
to be elucidated, several studies have demonstrated signifi-
removal. Using a bioabsorbable implant Giannini et al. report
cant improvements in key radiographic parameters reflecting
on outcomes in 21 children. Two patients required removal
both increased arch height and improved joint congruency
because of persistent pain with both cases resolving.24
following arthroereisis. Progressive loss of both static and
Resolution of pain following removal of the implants with no
dynamic stabilization of the foot with advancement of flat-
observed synovitis or bone damage was noted.88 By contrast
foot deformity may underpin, at least in part, suboptimal
Rockett et al. removed two uncemented STA-peg devices at 2
outcomes. Arthroereisis is an established yet evolving tech-
years due to pain associated with erosive and cystic changes
nique for the management of pediatric flatfoot deformity.
achieving only partial resolution of symptoms.62 In 2000,
As yet, future decision-making around intervention for flex-
Siff and Granberry reported on a single case of avascular
ible flatfoot remains clinical rather than evidence-based,
necrosis in one foot 10 years following bilateral arthroereisis
with no arthroereisis device demonstrating superiority over
using a polyethylene device.73 Biopsy confirmed avascular
another and based entirely on patient selection. The technical
necrosis and giant cell host response though device removal
simplicity of arthroereisis does not imply lack of correc-
resulted in significant improvement in symptoms. Metcalfe
tive power, nor longevity of correction. Where complica-
reported on pain following MBA arthroereisis device due
tions do arise, removal of the implant appears to usually
to erosion of the talar neck and recurrence of the flatfoot.51
leads to uncomplicated recovery without the irreversible
Symptoms resolved following device removal.
consequences sequelae seen with more aggressive interven-
Where arthroereisis fails, the majority of patients recover
tions. Application of disease specific validated outcome tools
to their preoperative state following implant removal.
together with standardization of reported data sets would may
Surgeons and patients should be alerted to the need to inves-
improve upon current evidence and permit comparison of
tigate postoperative discomfort early to mitigate the risk of
study data.
more serious complications.51,62 Careful preoperative assess-
ment is essential prior to correction of pediatric flatfoot. Such
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