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Lymphatic Research and Biology

Lymphatic Research and Biology is a quarterly, peer-reviewed

journal which will provide an interdisciplinary forum for the world’s
leading biomedical investigators to discuss current and anticipated
developments in lymphatic biology and pathology.

The Journal features fundamental scientific research of relevance to the

lymphatic system and publishes original work from a variety of
investigative disciplines, including genetics, biochemistry and biophysics,
cellular and molecular biology, physiology and pharmacology, anatomy,
developmental biology, and pathology. The Journal also encourages the
submission of state-of-the-art reviews in focus areas such as
vasculogenesis and angiogenesis, the genetics of lymphatic disorders,
muscle cell biology, interstitial signaling mechanisms, and others.

Each figure should be submitted in a separate TIFF or EPS file. (See

below.) References must be part of the manuscript text and not embedded
through a separate program, such as EndNote. Authors with questions
should address them to the Editorial Office at (516) 625-9675 or by e-mail
to journal@lymphaticresearch.org

Manuscript Submission

Manuscripts must be submitted online using the following URL:


Submissions should be formatted for US Letter paper (8.5 x11 inches).

Authors should attempt to reduce file sizes to 1 megaByte or less.
Manuscripts must contain title page, abstract, condensed abstract, text,
tables, figure legends.

General Instructions

1. Manuscripts should be prepared in Microsoft Word. Manuscripts should

be double-spaced. Number the pages, including the title page. Leave 1-
inch margins on all sides. Do not use justified margins.
2. Cite references, figures, and tables in numeric order. If any material has
been published previously (figures, tables, etc), provide written permission
from the copyright holder to use such material.
3. Consult the American Medical Association Manual of Style, 9th ed,
Baltimore, MD, Williams; Wilkins, 1998, for style.
4. Assemble the manuscript in this order: Title page, abstracts, text,
acknowledgments, references, figure legends, tables, and figures.
5. The title page (page 1) should contain these elements: Full title. Running
title (not to exceed 50 characters,including spaces). Authors' names,
academic degrees, and affiliations. Name and complete address for
correspondence (include street name and address as well as PO box) and
address for reprints if different from correspondence. Fax number,
telephone number, and E-mail address. Sources of support that require


Please supply a structured abstract of not more than 250 words, which
should be self-explanatory without reference to the text. Do not cite
references in the abstract. Limit use of acronyms and abbreviations. Define
at first use with acronym or abbreviation in parentheses. Use the following
headings: Background (rationale for study), Methods and Results (brief
presentation of methods and presentation of significant results; note that
both categories are included under one heading), and Conclusions
(succinct statement of data interpretation). Include a condensed abstract
of not more than 100 words for use in the annotated table of contents. It
need not adhere to the structured format.


The body of the manuscript should consist of the following sections in this
order: 1) Introduction, 2) Materials and Methods, 3) Results, 4)
Ethical Considerations in the Conduct and Reporting of

Protection of Human Subjects and Animals in Research

When reporting experiments on human subjects, authors should indicate

whether the procedures followed were in accordance with the ethical
standards of the responsible committee on human experimentation
(institutional and national) and with the Helsinki Declaration of 1975, as
revised in 2008. If doubt exists whether the research was conducted in
accordance with the Helsinki Declaration, the authors must explain the
rationale for their approach and demonstrate that the institutional review
body explicitly approved the doubtful aspects of the study. When reporting
experiments on animals, authors should indicate whether the institutional
and national guide for the care and use of laboratory animals was followed.

*This portion of the Instructions for Authors has been quoted directly from
the Uniform Requirements for Manuscripts Submitted to Biomedical
Journals website. For more information, visit

Tables and Illustrations

Prepare each table with its title on a separate page in Microsoft word. Each
table must stand alone and contain all necessary information in the legend.
The table itself must be comprehensible independently from the text.
Details of experimental conditions should be included in the table
footnotes. Information that appears in the text should not be repeated in a
table, and tables should not contain data that can be supplied within one or
two sentences in the text.

Figures must be submitted as either TIFF or EPS files and labeled as

Figure 1, Figure 2 and so on. Color figures and halftones must be at a
minimum 300 DPI resolution.
Color must be saved as CYMK. Black and white line drawings must be at a
minimum 1200 DPI resolution.
A list of figure legends should be supplied at the end of the manuscript,
double-spaced in Microsoft word. Magnifications should be included when
appropriate. Illustrations can be printed in color with a subsidy from the
author and are encouraged. Contact the publisher for details.

Disclosure Statement

Immediately following the Acknowledgments section, include a section

entitled “Author Disclosure Statement.” In this portion of the paper,
authors must disclose any commercial associations that might create a
conflict of interest in connection with submitted manuscripts. This
statement should include appropriate information for EACH author,
thereby representing that competing financial interests of all authors have
been appropriately disclosed according to the policy of the Journal. It is
important that all conflicts of interest, whether they are actual or potential,
be disclosed. This information will remain confidential while the paper is
being reviewed and will not influence the editorial decision. Please see the
Uniform Requirements for Manuscripts Submitted to Biomedical Journals
at http://www.icmje.org/index.html#conflicts for further guidance.

If no conflicts exist, the authors must state “No competing financial

interests exist."

When naming your figure files, please label them with your manuscript
number, followed by a period (.), and then list the figure number. Ex:
MET-2008-0123.Fig1. Label figures and tables inside the files in addition
to naming the file with the figure or table number. (ie: When figures or
table files are opened, the figure or table number should appear inside the


Please upload individual files of all manuscript material — do NOT upload

a single PDF file containing all text, figure, and table files of your paper.
Once all individual files are uploaded on to Manuscript Central, the system
will automatically create a single PDF proof for you and the peer-review

If no conflicts exist, the authors must state “No competing financial

interests exist."


References should be presented using the order of citation method. Please

place a numerical superior in the text that corresponds to the number in
the reference list. Below are examples of references in the reference list:

Journal articles

Jeltsch M., Kaipainen A., Joukov V., Meng X., Lakso M., Rauvala H.,
Swartz M., Fukumura D., Jain R.K., Alitalo K., Hyperplasia of lymphatic
vessels in VEGF-C transgenic mice. Science. 1997; 276: 1423-5

Book chapters Ferrara N., Gerber H., The Vascular Endothelial Growth
Factor Family. In: Ware J.A., Simons M. eds. Angiogenesis and
Cardiovascular Disease. New York: Oxford University Press; 1999: 101-27.

Please list each author’s name in the citation. If it is necessary to cite an

abstract, this should be designated. Abbreviations of journal titles should
follow Medline. Authors are responsible for the accuracy of the reference.
Only works referred to in the text and already accepted for publication can
be included.


The author must obtain permission to reproduce figures, tables, and text
from previously published material. Written permission must be obtained
from the original copyright holder (generally the publisher, not the author
or editor) of the journal or book concerned. An appropriate credit line
should be included in the figure or legend or table footnote, and full
publication information should be included in the reference list. Written
permission must be obtained from the author of any unpublished material
and should accompany the manuscript.


Reprints may be ordered by following the special instructions that will

accompany page proofs, and should be ordered at the time the
corresponding author returns the corrected page proofs to the Publisher.
Reprints ordered after an issue is printed will be charged at a substantially
higher rate.


Lymphatic Research and Biology is published by Mary Ann Liebert,

Inc., publishers, 140 Huguenot Street, New Rochelle, NY 10801-5215.
Telephone: (914) 740–2100; fax: (914) 740–2101.; E-mail: