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Wound

From Wikipedia, the free encyclopedia


(Redirected from Wound closure
<https://en.wikipedia.org/w/index.php?title=Wound_closure&redirect=no>)
Jump to: navigation <#mw-head>, search <#p-search>
This article is about wounds in humans and other animals. For wounds in
plants, see Plant pathology
<https://en.wikipedia.org/wiki/Plant_pathology>. For other uses, see
Wound (disambiguation)
<https://en.wikipedia.org/wiki/Wound_(disambiguation)>.
Wound
Chapter1figure1-Superficial bullet wound.jpg
<https://en.wikipedia.org/wiki/File:Chapter1figure1-Superficial_bullet_wound.jpg>

Wounds on a male torso


Classification and external resources
Specialty <https://en.wikipedia.org/wiki/Specialty_(medicine)>
Emergency medicine <https://en.wikipedia.org/wiki/Emergency_medicine>
ICD
<https://en.wikipedia.org/wiki/International_Statistical_Classification_of_Diseases
_and_Related_Health_Problems>-10
<https://en.wikipedia.org/wiki/ICD-10> T14.0
<http://apps.who.int/classifications/icd10/browse/2016/en#/T14.0>-T14.1
<http://apps.who.int/classifications/icd10/browse/2016/en#/T14.1>
ICD
<https://en.wikipedia.org/wiki/International_Statistical_Classification_of_Diseases
_and_Related_Health_Problems>-9-CM
<https://en.wikipedia.org/wiki/List_of_ICD-9_codes> 872
<http://www.icd9data.com/getICD9Code.ashx?icd9=872>-893
<http://www.icd9data.com/getICD9Code.ashx?icd9=893>
MeSH <https://en.wikipedia.org/wiki/Medical_Subject_Headings> D014947
<https://www.nlm.nih.gov/cgi/mesh/2018/MB_cgi?field=uid&term=D014947>
[edit on Wikidata <https://www.wikidata.org/wiki/Q184753>]

A *wound* is a type of injury <https://en.wikipedia.org/wiki/Injury>


which happens relatively quickly in which skin
<https://en.wikipedia.org/wiki/Skin> is torn, cut, or punctured (an
/open/ wound), or where blunt force trauma
<https://en.wikipedia.org/wiki/Physical_trauma> causes a contusion
<https://en.wikipedia.org/wiki/Bruise> (a /closed/ wound). In pathology
<https://en.wikipedia.org/wiki/Pathology>, it specifically refers to a
sharp injury which damages the dermis
<https://en.wikipedia.org/wiki/Dermis> of the skin.

Contents

[hide]
* 1 Classification <#Classification>
o 1.1 Open <#Open>
o 1.2 Closed <#Closed>
* 2 Pathophysiology <#Pathophysiology>
* 3 Diagnosis <#Diagnosis>
* 4 Management <#Management>
o 4.1 Cleaning <#Cleaning>
o 4.2 Closure <#Closure>
o 4.3 Dressings <#Dressings>
o 4.4 Alternative medicine <#Alternative_medicine>
* 5 Complications <#Complications>
o 5.1 Workup <#Workup>
o 5.2 Chronic <#Chronic>
* 6 History <#History>
* 7 Research <#Research>
* 8 See also <#See_also>
* 9 References <#References>
* 10 External links <#External_links>

Classification[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=1>]

According to level of contamination, a wound can be classified as:

* Clean wound – made under sterile conditions where there are no


organisms present, and the skin is likely to heal without complications.
* Contaminated wound – usually resulting from accidental injury; there
are pathogenic organisms and foreign bodies in the wound.
* Infected wound – the wound has pathogenic organisms present and
multiplying, exhibiting clinical signs of infection (yellow
appearance, soreness, redness, oozing pus
<https://en.wikipedia.org/wiki/Pus>).
* Colonized wound – a chronic situation, containing pathogenic
organisms, difficult to heal (i.e. bedsore
<https://en.wikipedia.org/wiki/Pressure_ulcer>).

Open[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=2>]

Open wounds can be classified according to the object that caused the wound:

* Incisions or incised wounds – caused by a clean, sharp-edged object


such as a knife <https://en.wikipedia.org/wiki/Knife>, razor
<https://en.wikipedia.org/wiki/Razor>, or glass splinter.
* Lacerations – irregular tear-like wounds caused by some blunt trauma
<https://en.wikipedia.org/wiki/Blunt_trauma>. Lacerations and
incisions may appear linear (regular) or stellate (irregular). The
term /laceration/ is commonly misused in reference to incisions.
Paper cuts are shallow lacerations.^[1] <#cite_note-1>
* Abrasions <https://en.wikipedia.org/wiki/Abrasion_(medical)>
(grazes) – superficial wounds in which the topmost layer of the skin
<https://en.wikipedia.org/wiki/Skin> (the epidermis) is scraped off.
Abrasions are often caused by a sliding fall onto a rough surface.
* Avulsions <https://en.wikipedia.org/wiki/Avulsion_(injury)> –
injuries in which a body structure is forcibly detached from its
normal point of insertion. A type of amputation where the extremity
is pulled off rather than cut off.
* Puncture wounds <https://en.wikipedia.org/wiki/Puncture_wound> –
caused by an object puncturing the skin
<https://en.wikipedia.org/wiki/Skin>, such as a splinter
<https://en.wikipedia.org/wiki/Splinter>, nail or needle
<https://en.wikipedia.org/wiki/Hypodermic_needle>.
* Penetration wounds
<https://en.wikipedia.org/wiki/Penetrating_trauma> – caused by an
object such as a knife entering and coming out from the skin.
* Gunshot wounds <https://en.wikipedia.org/wiki/Ballistic_trauma> –
caused by a bullet <https://en.wikipedia.org/wiki/Bullet> or similar
projectile driving into or through the body. There may be two
wounds, one at the site of entry and one at the site of exit,
generally referred to as a "through-and-through."

Closed[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=3>]

Closed wounds have fewer categories, but are just as dangerous as open
wounds:

* Hematomas <https://en.wikipedia.org/wiki/Hematoma> (or blood tumor)


– caused by damage to a blood vessel
<https://en.wikipedia.org/wiki/Blood_vessel> that in turn causes
blood <https://en.wikipedia.org/wiki/Blood> to collect under the
skin <https://en.wikipedia.org/wiki/Skin>.
o Hematomas that originate from internal blood vessel pathology
are petechiae <https://en.wikipedia.org/wiki/Petechiae>, purpura
<https://en.wikipedia.org/wiki/Purpura>, and ecchymosis
<https://en.wikipedia.org/wiki/Ecchymosis>. The different
classifications are based on size.
o Hematomas that originate from an external source of trauma are
contusions <https://en.wikipedia.org/wiki/Contusion>, also
commonly called bruises.
* Crush injury <https://en.wikipedia.org/wiki/Crush_injury> – caused
by a great or extreme amount of force applied over a long period of
time.

*
<https://en.wikipedia.org/wiki/File:Finger_abrasion.jpg>

An open wound (an avulsion)

*
<https://en.wikipedia.org/wiki/File:Laceration,_leg.jpg>

A laceration to the leg

*
<https://en.wikipedia.org/wiki/File:Footpuncture.JPG>

An infected puncture wound to the bottom of the forefoot.

*
<https://en.wikipedia.org/wiki/File:Knee_puncture.JPG>

A puncture wound from playing darts


<https://en.wikipedia.org/wiki/Darts>.
*
<https://en.wikipedia.org/wiki/File:Finger_cut.jpg>

An incision: a small cut in a finger.

*
<https://en.wikipedia.org/wiki/File:Schnitt_in_Fingerkuppe.jpg>

Fresh incisional wound on the fingertip of the left ring finger.

*
<https://en.wikipedia.org/wiki/File:ASC_Leiden_-_Coutinho_Collection_-_E_39_-
_Infirmary_in_Candjambary,_Guinea-Bissau_-_Cleaning_the_wound_-_1974.tif>

Abrasion of the lower leg. Guinea-Bissau, 1974

Pathophysiology[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=4>]

Main article: Wound healing <https://en.wikipedia.org/wiki/Wound_healing>

To heal <https://en.wikipedia.org/wiki/Healing> a wound, the body


undertakes a series of actions collectively known as the wound healing
<https://en.wikipedia.org/wiki/Wound_healing> process.

Diagnosis[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=5>]

A wound may be recorded for follow-up and observing progress of healing


with different techniques which include:^[2] <#cite_note-2>

* Photographs, with subsequent area quantification using computer


processing
* Wound tracings on acetate sheets
* Kundin wound gauge

Management[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=6>]

<https://en.wikipedia.org/wiki/File:Wound_sewed.jpg>

<https://en.wikipedia.org/wiki/File:Wound_sewed.jpg>
Wound, sewn with four stitches
<https://en.wikipedia.org/wiki/Surgical_suture>

The overall treatment depends on the type, cause, and depth of the
wound, and whether other structures beyond the skin (dermis) are
involved. Treatment of recent lacerations involves examining, cleaning,
and closing the wound. Minor wounds, like bruises, will heal on their
own, with skin discoloration usually disappearing in 1–2 weeks.
Abrasions <https://en.wikipedia.org/wiki/Abrasion_(medical)>, which are
wounds with intact skin (non-penetration through dermis to subcutaneous
fat), usually require no active treatment except keeping the area clean,
initially with soap and water. Puncture wounds
<https://en.wikipedia.org/wiki/Puncture_wound> may be prone to infection
depending on the depth of penetration. The entry of puncture wound is
left open to allow for bacteria or debris to be removed from inside.

Cleaning[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=7>]

Evidence to support the cleaning of wounds before closure is scant.^[3]


<#cite_note-Cochrane2012-3> For simple lacerations, cleaning can be
accomplished using a number of different solutions, including tap water
<https://en.wikipedia.org/wiki/Tap_water> and sterile saline solution
<https://en.wikipedia.org/wiki/Saline_(medicine)>.^[3]
<#cite_note-Cochrane2012-3> Infection rates may be lower with the use of
tap water in regions where water quality is high.^[3]
<#cite_note-Cochrane2012-3> Cleaning of a wound is also known as 'wound
toilet'.^[4] <#cite_note-4>

Closure[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=8>]

If a person presents to a healthcare center within 6 hours of a


laceration they are typically closed immediately after evaluating and
cleaning the wound. After this point in time, however, there is a
theoretical concern of increased risks of infection if closed
immediately.^[5] <#cite_note-Eliya2013-5> Thus some healthcare providers
may delay closure while others may be willing to immediately close up to
24 hours after the injury.^[5] <#cite_note-Eliya2013-5> Using clean
non-sterile gloves is equivalent to using sterile gloves during wound
closure.^[6] <#cite_note-6>

If closure of a wound is decided upon a number of techniques can be


used. These include bandages <https://en.wikipedia.org/wiki/Bandage>, a
cyanoacrylate <https://en.wikipedia.org/wiki/2-Octyl_cyanoacrylate>
glue, staples <https://en.wikipedia.org/wiki/Surgical_staple>, and
sutures <https://en.wikipedia.org/wiki/Surgical_suture>. Absorbable
sutures have the benefit over non absorbable sutures of not requiring
removal. They are often preferred in children.^[7] <#cite_note-7>
Buffering the pH <https://en.wikipedia.org/wiki/PH> of lidocaine
<https://en.wikipedia.org/wiki/Lidocaine> makes the injection less
painful.^[8] <#cite_note-8>

Adhesive glue and sutures have comparable cosmetic outcomes for minor
lacerations <5 cm in adults and children.^[9] <#cite_note-Cals-9> The
use of adhesive glue involves considerably less time for the doctor and
less pain for the person. The wound opens at a slightly higher rate but
there is less redness.^[10] <#cite_note-10> The risk for infections
(1.1%) is the same for both. Adhesive glue should not be used in areas
of high tension or repetitive movements, such as joints or the posterior
trunk.^[9] <#cite_note-Cals-9>

Dressings[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=9>]

In the case of clean surgical wounds, there is no evidence that the use
of topical antibiotics <https://en.wikipedia.org/wiki/Antibacterial>
reduces infection rates in comparison with non-antibiotic ointment or no
ointment at all.^[11] <#cite_note-AADfive-11> Antibiotic ointments can
irritate the skin, slow healing, and greatly increase the risk of
developing contact dermatitis
<https://en.wikipedia.org/wiki/Contact_dermatitis> and antibiotic
resistance <https://en.wikipedia.org/wiki/Antibiotic_resistance>.^[11]
<#cite_note-AADfive-11> Because of this, they should only be used when a
person shows signs of infection and not as a preventative.^[11]
<#cite_note-AADfive-11>

The effectiveness of dressings and creams containing silver to prevent


infection or improve healing is not currently supported by
evidence.^[12] <#cite_note-12> ^[/verification needed
<https://en.wikipedia.org/wiki/Wikipedia:Verifiability>/]

Alternative medicine[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=10>]

There is moderate evidence that honey is more effective than antiseptic


followed by gauze for healing wounds infected after surgical operations.
There is a lack of quality evidence relating to the use of honey on
other types of wounds, such as minor acute wounds, mixed acute and
chronic wounds, pressure ulcers, Fournier's gangrene, venous leg ulcers,
diabetic foot ulcers and Leishmaniasis.^[13] <#cite_note-13>

There is no good evidence that therapeutic touch


<https://en.wikipedia.org/wiki/Therapeutic_touch> is useful in
healing.^[14] <#cite_note-14> More than 400 species of plants are
identified as potentially useful for wound healing.^[15] <#cite_note-15>
Only three randomized controlled trials, however, have been done for the
treatment of burns.^[16] <#cite_note-16>

Complications[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=11>]

<https://en.wikipedia.org/wiki/File:Xraymachine.JPG>

<https://en.wikipedia.org/wiki/File:Xraymachine.JPG>
The patient has a deep wound at the knee, and radiography
<https://en.wikipedia.org/wiki/Radiography> is used to ensure there are
no hidden bone fractures <https://en.wikipedia.org/wiki/Bone_fractures>.

Bacterial infection <https://en.wikipedia.org/wiki/Infection> of wound


can impede the healing process and lead to life-threatening
complications. Scientists at Sheffield University
<https://en.wikipedia.org/wiki/Sheffield_University> have used light to
rapidly detect the presence of bacteria
<https://en.wikipedia.org/wiki/Bacteria>, by developing a portable kit
in which specially designed molecules emit a light signal when bound to
bacteria. Current laboratory-based detection of bacteria can take hours
or days.^[17] <#cite_note-17>

Workup[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=12>]

Wounds that are not healing should be investigated to find the causes;
many microbiological agents may be responsible. The basic workup
includes evaluating the wound, its extent and severity. Cultures are
usually obtained both from the wound site and blood. X-rays
<https://en.wikipedia.org/wiki/X-ray> are obtained and a tetanus shot
<https://en.wikipedia.org/wiki/Tetanus_vaccine> may be administered if
there is any doubt about prior vaccination.^[18] <#cite_note-18>

Chronic[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=13>]

Non-healing wounds of the diabetic


<https://en.wikipedia.org/wiki/Diabetes> foot are considered one of the
most significant complications of diabetes, representing a major
worldwide medical, social, and economic burden that greatly affects
patient quality of life. Almost 24 million Americans—one in every 12—are
diabetic and the disease is causing widespread disability and death at
an epidemic pace, according to the Centers for Disease Control and
Prevention. Of those with diabetes, 6.5 million are estimated to suffer
with chronic or non-healing wounds. Associated with inadequate
circulation, poorly functioning veins, and immobility, non-healing
wounds occur most frequently in the elderly and in people with
diabetes—populations that are sharply rising as the nation ages and
chronic diseases increase.

Although diabetes can ravage the body in many ways, non-healing ulcers
on the feet and lower legs are common outward manifestations of the
disease. Also, diabetics often suffer from nerve damage in their feet
and legs, allowing small wounds or irritations to develop without
awareness. Given the abnormalities of the microvasculature and other
side effects of diabetes, these wounds take a long time to heal and
require a specialized treatment approach for proper healing.

As many as 25% of diabetic patients will eventually develop foot ulcers,


and recurrence within five years is 70%. If not aggressively treated,
these wounds can lead to amputations. It is estimated that every 30
seconds a lower limb is amputated somewhere in the world because of a
diabetic wound. Amputation often triggers a downward spiral of declining
quality of life, frequently leading to disability and death. In fact,
only about one third of diabetic amputees will live more than five
years, a survival rate equivalent to that of many cancers.

Many of these lower extremity amputations can be prevented through an


interdisciplinary approach to treatment involving a variety of advanced
therapies and techniques, such as debridement, hyperbaric oxygen
treatment therapy, dressing selection, special shoes, and patient
education. When wounds persist, a specialized approach is required for
healing.^[19] <#cite_note-19>

History[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=14>]

<https://en.wikipedia.org/wiki/File:Treatment_of_wound_with_lance_grit.jpg>

<https://en.wikipedia.org/wiki/File:Treatment_of_wound_with_lance_grit.jpg>
Medieval treatment of wound with lance grittings

From the Classical Period


<https://en.wikipedia.org/wiki/Classical_antiquity> to the Medieval
Period <https://en.wikipedia.org/wiki/Medieval_Period>, the body and the
soul were believed to be intimately connected, based on several theories
put forth by the philosopher Plato
<https://en.wikipedia.org/wiki/Plato>. Wounds on the body were believed
to correlate with wounds to the soul and vice versa; wounds were seen as
an outward sign of an inward illness. Thus, a man who was wounded
physically in a serious way was said to be hindered not only physically
but spiritually as well. If the soul was wounded, that wound may also
eventually become physically manifest, revealing the true state of the
soul.^[20] <#cite_note-Gawain-20> Wounds were also seen as writing on
the "tablet" of the body. Wounds acquired in war, for example, told the
story of a soldier in a form which all could see and understand, and the
wounds of a martyr <https://en.wikipedia.org/wiki/Martyr> told the story
of their faith.^[20] <#cite_note-Gawain-20>

Research[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=15>]

In humans and mice it has been shown that estrogen might affect the
speed and quality of wound healing.^[21] <#cite_note-21>

See also[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=16>]

* European Wound Management Association


<https://en.wikipedia.org/wiki/European_Wound_Management_Association>
* International Red Cross Wound Classification System

<https://en.wikipedia.org/wiki/International_Red_Cross_Wound_Classification_System>
* Journal of Burns and Wounds
<https://en.wikipedia.org/wiki/Journal_of_Burns_and_Wounds>
* Wound bed preparation
<https://en.wikipedia.org/wiki/Wound_bed_preparation>

References[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=17>]

1. *Jump up ^ <#cite_ref-1>* Pediatrics, American Academy of (2011).


/First Aid for Families/
<https://books.google.com/books?id=6NDmgAL22s4C&pg=PA39>. Jones &
Bartlett Publishers. p. 39. ISBN
<https://en.wikipedia.org/wiki/International_Standard_Book_Number>
9780763755522
<https://en.wikipedia.org/wiki/Special:BookSources/9780763755522>.
2. *Jump up ^ <#cite_ref-2>* Thomas, A.C.; Wysocki, A.B. (February
1990). "The healing wound: a comparison of three clinically useful
methods of measurement". /Decubitus/. *3* (1): 18–20, 24–5. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 2322408
<https://www.ncbi.nlm.nih.gov/pubmed/2322408>.
3. ^ Jump up to: ^/*a*/ <#cite_ref-Cochrane2012_3-0> ^/*b*/
<#cite_ref-Cochrane2012_3-1> ^/*c*/ <#cite_ref-Cochrane2012_3-2>
Fernandez R., Griffiths R. (15 February 2012). "Water for wound
cleansing". /Cochrane Database of Systematic Reviews/. *2*:
CD003861. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD003861
.pub3
<https://doi.org/10.1002%2F14651858.CD003861.pub3>. PMID
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<https://www.ncbi.nlm.nih.gov/pubmed/22336796>. CS1 maint: Uses
authors parameter (link
<https://en.wikipedia.org/wiki/Category:CS1_maint:_Uses_authors_parameter>)
4. *Jump up ^ <#cite_ref-4>* /Simple wound management
<http://www.patient.info/doctor/Simple-Wound-Management-and-Suturing.htm>
Archived
<https://web.archive.org/web/20150627014103/http://patient.info/doctor/Simple-
Wound-Management-and-Suturing.htm>
27 June 2015 at the Wayback Machine
<https://en.wikipedia.org/wiki/Wayback_Machine>./, patient.info
(website), accessed 8 January 2012
5. ^ Jump up to: ^/*a*/ <#cite_ref-Eliya2013_5-0> ^/*b*/
<#cite_ref-Eliya2013_5-1> Eliya-Masamba, Martha C.; Banda, Grace W.
(2013-10-22). "Primary closure versus delayed closure for non bite
traumatic wounds within 24 hours post injury". /The Cochrane
Database of Systematic Reviews/ (10): CD008574. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD008574
.pub3
<https://doi.org/10.1002%2F14651858.CD008574.pub3>. ISSN
<https://en.wikipedia.org/wiki/International_Standard_Serial_Number> 1469-493X
<https://www.worldcat.org/issn/1469-493X>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 24146332
<https://www.ncbi.nlm.nih.gov/pubmed/24146332>.
6. *Jump up ^ <#cite_ref-6>* Brewer, JD; Gonzalez, AB; Baum, CL; Arpey,
CJ; Roenigk, RK; Otley, CC; Erwin, PJ (1 September 2016).
"Comparison of Sterile vs Nonsterile Gloves in Cutaneous Surgery and
Common Outpatient Dental Procedures: A Systematic Review and
Meta-analysis". /JAMA dermatology/. *152* (9): 1008–14. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 27487033
<https://www.ncbi.nlm.nih.gov/pubmed/27487033>.
7. *Jump up ^ <#cite_ref-7>* "BestBets: Absorbable sutures in pediatric
lacerations" <http://www.bestbets.org/bets/bet.php?id=874>. Archived

<https://web.archive.org/web/20081226233442/http://www.bestbets.org/bets/bet.php?
id=874>
from the original on 26 December 2008.
8. *Jump up ^ <#cite_ref-8>* Cepeda M.S., Tzortzopoulou A., Thackrey
M., Hudcova J., Arora Gandhi P., Schumann R. (2010). Tzortzopoulou,
Aikaterini, ed. "Adjusting the pH of lidocaine for reducing pain on
injection". /Cochrane Database Syst Rev/. *12* (12): CD006581. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD006581
.pub2
<https://doi.org/10.1002%2F14651858.CD006581.pub2>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 21154371
<https://www.ncbi.nlm.nih.gov/pubmed/21154371>. CS1 maint: Multiple
names: authors list (link

<https://en.wikipedia.org/wiki/Category:CS1_maint:_Multiple_names:_authors_list>)
9. ^ Jump up to: ^/*a*/ <#cite_ref-Cals_9-0> ^/*b*/
<#cite_ref-Cals_9-1> Cals, J.W.; de Bont EGPM (2012). "Minor incised
traumatic laceration" <http://www.bmj.com/content/345/bmj.e6824>.
/BMJ/. *345*: e6824. doi
<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1136/bmj.e6824
<https://doi.org/10.1136%2Fbmj.e6824>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 23092899
<https://www.ncbi.nlm.nih.gov/pubmed/23092899>. Archived
<https://web.archive.org/web/20131105202631/http://www.bmj.com/content/345/bmj.e682
4>
from the original on 5 November 2013.
10. *Jump up ^ <#cite_ref-10>* Farion, K; et al. (2002). Farion, Ken J.,
ed. "Tissue adhesives for traumatic lacerations in children and
adults". /Cochrane Database Syst Rev/ (3): CD003326. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD003326
<https://doi.org/10.1002%2F14651858.CD003326>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 12137689
<https://www.ncbi.nlm.nih.gov/pubmed/12137689>.
11. ^ Jump up to: ^/*a*/ <#cite_ref-AADfive_11-0> ^/*b*/
<#cite_ref-AADfive_11-1> ^/*c*/ <#cite_ref-AADfive_11-2> American
Academy of Dermatology
<https://en.wikipedia.org/wiki/American_Academy_of_Dermatology>
(February 2013), "Five Things Physicians and Patients Should
Question"
<http://www.choosingwisely.org/doctor-patient-lists/american-academy-of-
dermatology/>,
/Choosing Wisely <https://en.wikipedia.org/wiki/Choosing_Wisely>: an
initiative of the ABIM Foundation
<https://en.wikipedia.org/wiki/ABIM_Foundation>/, American Academy
of Dermatology
<https://en.wikipedia.org/wiki/American_Academy_of_Dermatology>,
archived

<https://web.archive.org/web/20131201171621/http://www.choosingwisely.org/doctor-
patient-lists/american-academy-of-dermatology/>
from the original on 1 December 2013, retrieved 5 December 2013 ,
which cites
* Sheth, V. M.; Weitzul, S. (2008). "Postoperative topical
antimicrobial use". /Dermatitis: contact, atopic, occupational,
drug/. *19* (4): 181–9. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 18674453
<https://www.ncbi.nlm.nih.gov/pubmed/18674453>.
12. *Jump up ^ <#cite_ref-12>* D'Amico G., Pagliaro L., Pietrosi G.,
Tarantino I. (2010). d'Amico, Gennaro, ed. "Emergency sclerotherapy
versus vasoactive drugs for bleeding oesophageal varices in
cirrhotic patients". /Cochrane Database Syst Rev/. *3* (3):
CD002233. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD002233
.pub2
<https://doi.org/10.1002%2F14651858.CD002233.pub2>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 20238318
<https://www.ncbi.nlm.nih.gov/pubmed/20238318>. CS1 maint: Multiple
names: authors list (link

<https://en.wikipedia.org/wiki/Category:CS1_maint:_Multiple_names:_authors_list>)
13. *Jump up ^ <#cite_ref-13>* Jull AB, Cullum N, Dumville JC, Westby
MJ, Deshpande S, Walker N (6 March 2015). "Honey as a topical
treatment for wounds". /Cochrane Database of Systematic Reviews/.
*3*: CD005083. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD005083
.pub4
<https://doi.org/10.1002%2F14651858.CD005083.pub4>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 25742878
<https://www.ncbi.nlm.nih.gov/pubmed/25742878>.
14. *Jump up ^ <#cite_ref-14>* O'Mathúna, Dónal P. (2016-08-23).
"Therapeutic touch for healing acute wounds". /The Cochrane Database
of Systematic Reviews/ (8): CD002766. doi

<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1002/14651858.CD002766
.pub5
<https://doi.org/10.1002%2F14651858.CD002766.pub5>. ISSN
<https://en.wikipedia.org/wiki/International_Standard_Serial_Number> 1469-493X
<https://www.worldcat.org/issn/1469-493X>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 27552401
<https://www.ncbi.nlm.nih.gov/pubmed/27552401>.
15. *Jump up ^ <#cite_ref-15>* Ghosh, P.K.; Gaba, A. (2013).
"Phyto-extracts in wound healing". /Journal of pharmacy &
pharmaceutical sciences: a publication of the Canadian Society for
Pharmaceutical Sciences, Societe canadienne des sciences
pharmaceutiques/. *16* (5): 760–820. doi
<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.18433/j3831v
<https://doi.org/10.18433%2Fj3831v>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 24393557
<https://www.ncbi.nlm.nih.gov/pubmed/24393557>.
16. *Jump up ^ <#cite_ref-16>* Bahramsoltani, R.; Farzaei, M.H.; Rahimi,
R. (September 2014). "Medicinal plants and their natural components
as future drugs for the treatment of burn wounds: an integrative
review". /Archives of dermatological research/. *306* (7): 601–17.
doi
<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.1007/s00403-014-
1474-6
<https://doi.org/10.1007%2Fs00403-014-1474-6>. PMID
<https://en.wikipedia.org/wiki/PubMed_Identifier> 24895176
<https://www.ncbi.nlm.nih.gov/pubmed/24895176>.
17. *Jump up ^ <#cite_ref-17>* "Light to detect wound infection"
<http://news.bbc.co.uk/1/hi/health/6427787.stm> (web). /UK
scientists have identified a way of using light to rapidly detect
the presence of bacteria/. BBC News. 11 March 2007. Archived

<https://web.archive.org/web/20070822194515/http://news.bbc.co.uk/1/hi/health/64277
87.stm>
from the original on 22 August 2007. Retrieved 17 March 2008.
18. *Jump up ^ <#cite_ref-18>* Work Up
<http://emedicine.medscape.com/article/188988-diagnosis> Archived

<https://web.archive.org/web/20100131022943/http://emedicine.medscape.com/article/1
88988-diagnosis>
31 January 2010 at the Wayback Machine
<https://en.wikipedia.org/wiki/Wayback_Machine>. eMedicine General
Surgery. Retrieved 27 January 2010
19. *Jump up ^ <#cite_ref-19>* "The Clinical Case for Use of Hyperbaric
Oxygen Therapy in the Treatment of Diabetic Wounds," Diversified
Clinical Services, copyright 2009
20. ^ Jump up to: ^/*a*/ <#cite_ref-Gawain_20-0> ^/*b*/
<#cite_ref-Gawain_20-1> Reichardt, Paul F. (1984). "Gawain and the
image of the wound". /PMLA/. *99* (2): 154–161. doi
<https://en.wikipedia.org/wiki/Digital_object_identifier>:10.2307/462158
<https://doi.org/10.2307%2F462158>. JSTOR
<https://en.wikipedia.org/wiki/JSTOR> 462158
<https://www.jstor.org/stable/462158>.
21. *Jump up ^ <#cite_ref-21>* Desiree May Oh, MD, Tania J. Phillips, MD
(2006). "Sex Hormones and Wound Healing"
<http://www.medscape.com/viewarticle/524313_3>. /Wounds/. Archived

<https://web.archive.org/web/20130107094207/http://www.medscape.com/viewarticle/524
313_3>
from the original on 7 January 2013. CS1 maint: Multiple names:
authors list (link

<https://en.wikipedia.org/wiki/Category:CS1_maint:_Multiple_names:_authors_list>)

External links[edit
<https://en.wikipedia.org/w/index.php?title=Wound&action=edit&section=18>]

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* US based wound healing society <http://www.woundheal.org/>


* Association for the Advancement of Wound Care
<http://www.aawconline.org/> AAWC
* European Wound Management Association <http://www.ewma.org/> - EWMA
works to promote the advancement of education and research.

[hide <#>]

* v <https://en.wikipedia.org/wiki/Template:General_injuries>
* t <https://en.wikipedia.org/wiki/Template_talk:General_injuries>
* e
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General wounds and injuries <https://en.wikipedia.org/wiki/Injury>


(T08-T35
<https://en.wikipedia.org/wiki/ICD-
10_Chapter_XIX:_Injury,_poisoning_and_certain_other_consequences_of_external_causes
#(T08%E2%80%93T14)_unspecified_parts_of_trunk,_limb_or_body_region>,
870-949
<https://en.wikipedia.org/wiki/List_of_ICD-
9_codes_800%E2%80%93999:_injury_and_poisoning>)
Abrasions

* Abrasion <https://en.wikipedia.org/wiki/Abrasion_(medical)>
o Avulsion <https://en.wikipedia.org/wiki/Avulsion_injury>

Blisters <https://en.wikipedia.org/wiki/Blister>

* Blood blister <https://en.wikipedia.org/wiki/Blood_blister>


* Coma blister <https://en.wikipedia.org/wiki/Coma_blister>
* Delayed blister <https://en.wikipedia.org/wiki/Delayed_blister>
* Edema blister <https://en.wikipedia.org/wiki/Edema_blister>
* Fracture blister <https://en.wikipedia.org/wiki/Fracture_blister>
* Friction blister <https://en.wikipedia.org/wiki/Friction_blister>
* Sucking blister <https://en.wikipedia.org/wiki/Sucking_blister>
Bruises <https://en.wikipedia.org/wiki/Bruise>

* Hematoma <https://en.wikipedia.org/wiki/Hematoma>/Ecchymosis
<https://en.wikipedia.org/wiki/Ecchymosis>
o Battle's sign <https://en.wikipedia.org/wiki/Battle%27s_sign>
o Raccoon eyes <https://en.wikipedia.org/wiki/Raccoon_eyes>
o Black eye <https://en.wikipedia.org/wiki/Black_eye>
o Subungual hematoma
<https://en.wikipedia.org/wiki/Subungual_hematoma>
o Cullen's sign <https://en.wikipedia.org/wiki/Cullen%27s_sign>
o Grey Turner's sign
<https://en.wikipedia.org/wiki/Grey_Turner%27s_sign>
o Retroperitoneal hemorrhage
<https://en.wikipedia.org/wiki/Retroperitoneal_hemorrhage>

Animal bites <https://en.wikipedia.org/wiki/Bite>

* Insect bite <https://en.wikipedia.org/wiki/Insect_bites_and_stings>


* Spider bite <https://en.wikipedia.org/wiki/Spider_bite>
* Snakebite <https://en.wikipedia.org/wiki/Snakebite>

Other:

* Ballistic trauma <https://en.wikipedia.org/wiki/Ballistic_trauma>


* Stab wound <https://en.wikipedia.org/wiki/Stab_wound>
* Blunt trauma <https://en.wikipedia.org/wiki/Blunt_trauma>/
superficial/closed <https://en.wikipedia.org/wiki/Wound#Closed>
* Penetrating trauma
<https://en.wikipedia.org/wiki/Penetrating_trauma>/open
<https://en.wikipedia.org/wiki/Wound#Open>
* Aerosol burn <https://en.wikipedia.org/wiki/Aerosol_burn>
* Burn <https://en.wikipedia.org/wiki/Burn>/Corrosion
<https://en.wikipedia.org/wiki/Corrosion>/Chemical burn
<https://en.wikipedia.org/wiki/Chemical_burn>
* Frostbite <https://en.wikipedia.org/wiki/Frostbite>
* Occupational injuries
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* Traumatic amputation <https://en.wikipedia.org/wiki/Amputation#Trauma>

By region

* Hand injury <https://en.wikipedia.org/wiki/Hand_injury>


* Head injury <https://en.wikipedia.org/wiki/Head_injury>
* Chest trauma <https://en.wikipedia.org/wiki/Chest_injury>
* Abdominal trauma <https://en.wikipedia.org/wiki/Abdominal_trauma>

Authority control <https://en.wikipedia.org/wiki/Help:Authority_control>

* GND <https://en.wikipedia.org/wiki/Integrated_Authority_File>:
4191910-5 <https://d-nb.info/gnd/4191910-5>
* NDL <https://en.wikipedia.org/wiki/National_Diet_Library>: 00571467
<https://id.ndl.go.jp/auth/ndlna/00571467>

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