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Summary
Challenge 1
1.Personalized Medicine
Challenges:
a. developing better systems to rapidly assess a patient’s
genetic profile
b. collecting and managing massive amounts of data on
individual patients
c. yet another is the need to create inexpensive and rapid
diagnostic devices such as gene chips and sensors able to detect minute
amounts of chemicals in the blood
"The current “gold standard” for testing a drug’s worth and safety is the
randomized controlled clinical trial -- a study that randomly assigns people to
a new drug or to nothing at all, a placebo, to assess how the drug performs.
But that approach essentially decides a drug’s usefulness based on average
results for the group of patients as a whole, not for the individual."
2.Drug-resistant Infections
“Drug-resistant pathogens — whether parasites, bacteria, or viruses — can
no longer be effectively treated with common anti-infective drugs,” writes
David L. Heymann of the World Health Organization."
Attempts:
1.Combine an antibiotic with a second drug that has little antibiotic effect but
possesses the power to disarm a bacterial defense molecule. (Hybrid
treatment)
Example of problems:
1. Bacteria
2. Antibiotics
3. Anti-viral drugs for AIDS and influenza
1. Other than the mentioned challenges within this topic, are there more?
2. What are the limitations of current attempts?