Академический Документы
Профессиональный Документы
Культура Документы
Stage Description
I A single tumor or nodal area of involvement outside the abdomen and
mediastinum
II A single tumor with regional node involvement, two or more tumors or
nodal areas of involvement on one side of the diaphragm, or a primary
gastrointestinal tract tumor (resected) with or without regional node
involvement
III Tumors or nodal areas of involvement on both sides of the diaphragm,
any primary intrathoracic or extensive intraabdominal disease, or any
paraspinal or epidural tumors
IV Bone marrow disease*or CNS disease† regardless of other sites of
involvement
*Defined as 5% malignant cells in otherwise normal bone marrow with normal peripheral blood cell counts and smears.
Patients with lymphoblastic lymphoma with more than 25% malignant cells in bone marrow are usually considered to have
leukemia and may be appropriately treated in leukemia clinical trials.† CNS disease in lymphoblastic lymphoma is defined
with criteria similar to those used for acute lymphocytic leukemia (ie, white blood cell count 5/L or greater with malignant
cells). For small noncleaved cell or large cell lymphoma, however, the definition of CNS disease is the presence of any
malignant cell regardless of cell count