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THE INCREDIBLE STORY OF THE BIG BANG

John Gribbin explores the epic discovery of how our Universe began

Water world
Is there alien life on
Saturn’s moon?

Why we love
alcohol
Blame the monkeys

Animal
invaders
When Nature just
can’t be stopped
sciencefocus.com
ISSUE 268 / JUNE 2014 Artificial
intelligence
Drive smarter When will computers
We test the cars that match the human brain?
think for themselves

Manuscript
mystery
Has an ancient puzzle
been solved at last?

NASA
Starshade
vk.
com/
engl
ishl
ibr
ary
10
The spacecraft that will
find Earth’s twin

DISCOVERIES
that will shape
the future

Q&A
�How much of the Universe
can we see from Earth?
�Why do we get used to smells?
�Do photos help us remember?
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WELCOME
WOULD YOU LIKE to live to 100? Given the choice, and
the prospect of good health, I suspect most of us would.
So it’s perhaps not surprising that this is the new goal FOCUS DIGITAL
of companies at the cutting edge of genetic research. AVAILABLE ON YOUR DEVICE NOW!
They’re using the new power of genomics to target age-
related disease like diabetes, heart disease, dementia and
cancer. Can they succeed? Health writer Lilian Anekwe
THIS MONTH WE…
finds out on p39. And if you can’t wait for Google (Calico) …went behind the
or Craig Venter (Human Longevity Inc), we provide some scenes to film the
rehearsals for The
tips to help you increase your lifespan today. Energy Show, a stage
Cutting down on alcohol intake is usually recommended where health is production by Science
Museum Live. Watch it on
concerned. But it seems that our fondness for a tipple has been with us for a our YouTube channel at
lot longer than you might think, as Prof Robert Dudley (author of The Drunken youtube.com/ScienceFocus
Monkey) explains on p75. …drove four cars
You may have heard of the recent discovery that confirmed ‘inflation’, the with the very latest
rapid period of expansion after the Big Bang. As it happens, confirmation of the built-in technology
and filmed 360° panoramas
Big Bang theory itself is 50 years old this summer. Top science author John of the interiors for our
Gribbin reveals the fascinating story on p92. interactive iPad app.
Find out what we made
Elsewhere, we look at the ancient manuscript whose secret codes may finally of the cars on p86.
have been cracked (p56); what high-vis cycling jackets have in common with
...spoke to leading
scorpions (p31); and what happens when animals become alien invaders (p72). neurosurgeon Henry
Marsh. He told us about
the challenges of operating
P.S. on the brain and the
high-risk nature of the
Don’t miss our July issue, job. Listen to him on this
Graham Southorn, Editor on sale 29 May 2014 month’s podcast.

CONTACTS EDITORIAL ENQUIRIES


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APPEARING IN THIS ISSUE…


Lilian Helen John David
Anekwe Czerski Gribbin Shukman
Lilian is the consumer In her regular column John is an astrophysicist The BBC science
health editor for the this month the and an award-winning editor is our new
weekly journal BMJ. oceanographer, author of popular regular columnist in the
She looks at the companies aiming to physicist and BBC science presenter science books including Computing Discoveries section. This month he
help us all live to the age of 100 with explains what high-vis cycling jackets With Quantum Cats. He uncovers the explores how global warming will take
the help of genetics (p39). have in common with scorpions (p31). history of the Big Bang theory on p92. its toll on the world’s food supply (p22).
COVER: JUSTIN METZ

WANT TO Turn to p32 to save 40% on SUBSCRIBER On p32 Dr Lewis Dartnell explores questions at the
SUBSCRIBE? the full subscription rate BONUS frontiers of astrobiology, the science of life on other worlds
CONTENTS JUNE 2014

ON THE COVER

19 WATER WORLD
39 HOW TO LIVE TO 100
56 MYSTERY BOOK
63 Q&A
72 ANIMAL INVADERS
75 A TASTE FOR ALCOHOL
87 DRIVE SMARTER 39
PHOTO: PRESS ASSOCIATION, SCIENCE PHOTO LIBRARY, SECRETSTUDIO.NET, BEINECKE RARE BOOK & MANUSCRIPT LIBRARY, MAGICTORCH, NATUREPL.COM

92 THE BIG BANG THEORY

FEATURES

HOW TO LIVE
39 TO 100
Is longevity determined by
your genes? A growing
body of evidence suggests
it may well be…

UNDER
49 PRESSURE
New research is showing
that at extreme pressures,
compounds behave in some
72 56 92
unexpected ways
49
THE VOYNICH
56 MANUSCRIPT
Could this indecipherable
medieval book finally be
about to give up its secrets?

ALIEN
72 INVADERS
The plants and animals that
have caused enormous
destruction simply by being
in the wrong place

WHY WE 75
75 LOVE ALCOHOL
Why your fondness for a
pint of cold lager may have

32 SUBSCRIBE TODAY!
its roots in the diet of your
prehuman ancestors

92 HOW DO

SAVE 40%
WE KNOW…?
How we know the Universe
began with a Big Bang

6 / FOCUS / JUNE 2014


114

26 84 87

37 81 63

DISCOVERIES COLUMNS TECH HUB TO DO LIST PLUS…

19 UNDERGROUND OCEAN 22 DAVID SHUKMAN 81 XEROS WATERLESS 99 PICK OF THE MONTH 8 MEGAPIXEL
Sub-surface water discovered The BBC Science Editor on WASHING MACHINE As Horizon approaches its Stunning science images
on Saturn’s moon Enceladus climate change and food The appliance that lets beads 50th birthday, we look at the from around the world
clean your laundry highlights of the new series
24 MOUSE BRAIN MAPPED 29 ROBERT MATTHEWS 16 REPLY
We’re a step closer to truly The Steady State theory of 84 MUSICAL FIDELITY 100 WATCH & LISTEN Your letters, emails and tweets
understanding how brains work the Universe remembered V90 SERIES Science on TV and radio
The most compact and bijou 63 Q&A
26 DISCOVERIES THAT 31 HELEN CZERSKI hi-fi separates around 102 TOUCH What percentage of the
WILL SHAPE THE FUTURE The hidden science of Smartphone and tablet apps Universe is visible? How do
The latest major breakthroughs high-visibility clothing 85 APPLIANCES polar bears keep warm?
in science and technology OF SCIENCE 103 VISIT Our experts answer these
37 STEPHEN BAXTER Cool and clever new kit Great science days out questions and many more!
30 THE WOMAN WITH A Could we build a ‘gravity train’?
3D-PRINTED SKULL 87 ULTIMATE TEST 104 READ 111 MINDGAMES
Technique o�ers new hope 114 HOLLYWOOD SCIENCE We test-drive four The month’s books, featuring A quiz and crossword to give
for accident victims This month: Transcendence technology-enhanced cars Do No Harm and more your grey matter a workout

BE AN INSIDER We want to know what you think – the more we know about you, the better placed we are to bring you the best magazine
possible. So join our online reader panel, ‘Insiders’. Log on to www.immediateinsiders.com/register to fill out a short
survey and we’ll be in touch from time to time to ask for your opinions on the magazine. We look forward to hearing from you.

BBC Focus Magazine (ISSN 0966-4270) is published 13 times a year by Immediate Media Company Bristol, 9th Floor, Tower House, Fairfax Street, Bristol BS1 3BN, UK. Distributed in the US by Circulation Specialists, Inc., 2 Corporate Drive, Suite 945,
Shelton CT 06484-6238. Application to mail at Periodicals Postage prices pending at Shelton, CT and additional mailing o�ces. POSTMASTER: Send address changes to BBC Focus Magazine, P.O. Box 37495, Boone, IA 50037-0495.

JUNE 2014 / FOCUS / 7


Awe-inspiring images from the world of science

Hat scan
WHY WOULD YOU wear a QR code on
your head? In the case of volunteers
in the BaSiGo project, it’s so that they
could be tracked to find out more
about crowd behaviour.
Over three days in June 2013, up
to 1,000 volunteers in the Düsseldorf
Exhibition Centre in Germany were
put through a series of obstacle
courses. The QR codes were picked
up by 24 ceiling-mounted cameras
and turned into computer data.
The aim was to improve models of
crowd behaviour to prevent crushes
like the one that killed 21 people and
injured hundreds of others at the
Love Parade festival in Duisburg,
Germany, in 2010.
The experiments were jointly
carried out by the universities of
Siegen and Jülich. The scientists
varied the crowd density, and added
signs and obstructions to see how
they a�ected the flow of people: “For
cars there are rules, crossings and
tracks. We’ve learned that we can
also influence pedestrians,” says lead
researcher Prof Armin Seyfried.

PHOTO: LAIF/DAVID KLAMMER/CAMERAPRESS

8 / FOCUS / JUNE 2014


For more great pictures, follow us on
http://pinterest.com/sciencefocus

JUNE 2014 / FOCUS / 9


10 / FOCUS / JUNE 2014
Explosive altruism
AS FAR AS taking one for the team
goes, Borneo’s carpenter ants are
up there with the best of them. When
attacked by predators, such as the
larger worker ant pictured here,
the bomb-like bugs grab onto their
assailants and hit the self-destruct
button, spraying toxic yellow glue
into the air.
“Ants have a mandibular gland
that is normally confined to the
head,” explains entomologist and
BBC presenter Adam Hart. “However,
in some species of carpenter ants
the gland is enormous and runs
down the length of the body. As a
last-ditch defence mechanism, the
ant can violently contract muscles
that cause its abdomen and the
mandibular glands to rupture. This
sprays the sticky, corrosive contents
all over its attacker.”
This defence mechanism is known
as ‘autothysis’ and is also seen in
some species of termite.

PHOTO: MARK MOFFETT/FLPA

JUNE 2014 / FOCUS / 11


A throw of the dice
MORE THAN 320KM (200 The CubeSat furthest
miles) above the Earth, to the right in this photo,
three tiny satellites are FITSAT-1, was built by
hurled into space. Known as Japan’s Fukuoka Institute
CubeSats, these miniature of Technology. In orbit until
machines measure just July 2013, it sported a
10x10x10 centimetres. high-speed transmitter that
They were launched from could beam back images
the International Space within six seconds. More
Station in October 2012, recently, 28 CubeSats were
released by a deployer launched by US company
attached to one of the Planet Labs, with the aim
station’s robotic arms. of creating the world’s
“Well over 100 CubeSats largest flock of Earth-
have been launched into imaging satellites.
space since 2003,” says But it looks like this is just
Prof Jordi Puig-Suari, the beginning. “In the very
co-inventor of the CubeSat near future we expect NASA
design. “Initially they to start launching
were primarily teaching interplanetary CubeSats,”
tools, but they’ve also says Puig-Suari.
moved on to perform
‘real’ missions.” PHOTO: NASA

12 / FOCUS / JUNE 2014


JUNE 2014 / FOCUS / 13
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Your opinions on science, technology and BBC Focus Magazine Letters may be edited for publication

Astrology: no free will


MESSAGE OF THE MONTH With reference to the letter in your
April issue from Chris MacLennan,
which claimed that [astrologer] Lada
Duncheva’s predictions on YouTube are
‘astoundingly accurate’, there are two
possibilities. [1] The future is not yet
determined, in which case predicting
it by any method is impossible. [2] The
future is already decided, in which case
there may be people who can see into it.
But if [2] is the case, there is no free
will. Everything we do is waiting to
happen. PS I bet Lada Duncheva is really
called ‘Bert’.
Colin Jack, Worcester

I won’t comment on Lada Duncheva,


but I am giving Colin the last word on
astrology! –Ed

“Doesn’t look much like


a palace to me, Holmes.” VW parks itself
Your article about the Ford Kuga (April,
p92) seemed to infer that its self-parking

Medieval mind training system was unique and new to a car


of that class. I have been driving a VW
Tiguan with the self-parking option for
the last four years. I have to say its main
The article on memory (April, p43) was mind. These skill sets have much in function has been to use it as a party
very informative, but only dealt with common with sports psychology, which piece to impress friends!
artificially modifying the way the brain has produced a considerable performance However, it has never let me down
works. Over many centuries, much work increase in recent years. At the core of when showing it off. A couple of weeks
has been done on memory improvement. these methods is the understanding that ago I had to park in a city centre where
The ‘memory palace’ (featured in the memory works mainly in visual images and on-street parking was very limited. The
recent series of Sherlock) was used not in words and numbers. self-parking got me into a space with only
extensively in the ancient world. The Before we set off into the world of a very small amount of room at either
Renaissance was interested in memory mind-altering drugs etc, I believe that end of the car. I understand that the first
enhancement, and it was a preoccupation these ancient memory techniques should medium-priced car that the VW group
of the Italian philosopher Giordano Bruno. be properly tested in controlled laboratory fitted with the self-parking option was
Dame Frances Yates’ book The Art Of conditions to determine their effectiveness. the Skoda Superb.
Memory details many of these systems. Paul Jeffels, Derby Ken Wallace
In recent times the World Memory
Championship has re-introduced Good point, Paul. You’re right that our
‘location method’, ‘journey method’ and feature focused mostly on the latest findings
visualisation techniques to achieve feats in neuroscience, but Focus has covered the
of memory beyond those of an untrained World Memory Championships in the past.
PHOTO: ALAMY, SCIENCE PHOTO LIBRARY

Write in and win!


The writer of next issue’s Message of the Month wins a Lantronix
xPrintServer Cloud Print worth £91. Simply plug this compact
device into your home network and you’ll be able to print from
your Android phone, tablet or PC using your existing printer. If you have an iPhone
instead, the xPrintServer iOS does the same job. www.lantronix.com
The self-parking Ford Kuga is nothing new, says Ken Wallace

16 / FOCUS / JUNE 2014


Yes, I am mad Inside bacteria
When I got to the item entitled ‘Are you In the February edition, your article
mad?’ (March, p54), I was astonished to ‘How to beat the lurgy’ (p103) suggested
learn that there was such a publication as that bacteria have “a nucleus containing EDITORIAL
The Diagnostic And Statistical Manual Of genetic material”. Editor Graham Southorn
Production Editor Daniel Down
Mental Disorders. As I read further in the Bacteria are prokaryotes: their genetic Reviews Editor Daniel Bennett
article, I realised that my long-held view material consists of loops of DNA Commissioning Editor Jason Goodyer
Editorial Assistant James Lloyd
of psychiatrists was indeed correct and floating freely within the cell. It Science Consultant Robert Matthews
that they don’t seem to have a grasp of is eukaryotes, such as plants and Contributing Editor Emma Bayley
the real world. animals, that have cells within ART & PICTURES
I must assume that, within this august discrete nuclei. I would have Art Editor Joe Eden
publication, they have included their own been less surprised to have read Designer Jon Rich
Picture Editor James Cutmore
mental diagnosis: “a desire in Focus that a whale is a type
to create meaningless lists of fish, as whales and fish at CONTRIBUTORS
Lilian Anekwe, Sarah Bane, Michael Banks, Stephen
of unproven views and foist least both possess nuclei, Baxter, Susan Blackmore, Christopher Brennan,
them on their peer group”. which bacteria do not. Tracie Ching, Brian Clegg, Helen Czerski, Lewis
As for me, I guess I would be Richard Kettlewood, Dartnell, Russell Deeks, Robert Dudley, Dale Edwin
Murray, John Gribbin, Alastair Gunn, Monty Halls,
classed as “an unwillingness Goole Timandra Harkness, Adam Howling, Justin Metz,
to subscribe to the Gareth Mitchell, Michael Mosley, Kelly Oakes, Jheni
Osman, Mark Pagel, Ciara Phelan, Helen Pilcher, Andy
Emperor’s New Clothes Apologies: that sentence Potts, David Shukman, Giles Sparrow, Secret Studio,
syndrome” and a disbeliever should have said ‘nucleoid’ Ken Thompson, Bill Thompson, Magic Torch, Jan Van
Der Veken, Luis Villazon
in psychobabble. Yes, I am not ‘nucleus’. –Ed
mad and proud of it! ADVERTISING & MARKETING
Keith Tittensor Advertising Director Caroline Herbert
Advertising Manager Steve Grigg
Deputy Advertising Manager Marc Gonzalez
Brand Sales Executive James Young
The hole truth YOUR COMMENTS ON Classified Sales Executive Carl Kill
Newstrade Manager Rob Brock
I recently picked up a copy of your TWITTER & Subscriptions Director Jacky Perales-Morris
Direct Marketing Executive Chris Day
magazine, and stumbled across the article
‘Why are some people afraid of holes?’ FAC E BOOK Direct Marketing Manager Mark Summerton

(April, p73). Out of curiosity, INSERTS


Laurence Robertson 00353 876 902208
I read it and looked closely
We asked: ‘British dog lover Rebecca
at the supplementary picture LICENSING & SYNDICATION
Smith has had her dog cloned. Would International Partners Manager Anna Brown
of a creature [the blue-
you consider cloning your pet?’
ringed octopus]. PUBLICIT Y
Suffice to say, my Ross Kobak No. Never mind the Press O�cer Carolyn Wray
life will never be genetic defects and illnesses caused
PRODUCTION
the same again! by cloning, which is still a far from Production Director Sarah Powell
Absolutely repulsive, perfect science. Never mind the Production Coordinator Emily Mounter
arguments between nature and Ads Services Manager Paul Thornton
and so disgusting that I Ad Coordinator Jade O’Halloran
now have a constant itch. nurture. This is one of those times Ad Designer Matt Gynn
Nicole Cheung when people should think, “Just
PUBLISHING
because I can does not mean I Publisher Andrew Davies
should.” Better yet, she could have Chairman Stephen Alexander
No rest for the rich adopted one of the countless dogs in Chief Executive O�cer Tom Bureau
Deputy Chairman Peter Phippen
animal shelters.
Re: your ‘Message of the Month’ in the Managing Director Andy Marshall
April issue about robots making us idle. @SSigurnjak No. What you grow to BBC WORLDWIDE, UK PUBLISHING
I literally laughed out loud at Geoff love is their personality based on life Director of UK Publishing Nicholas Brett
Head of UK Publishing Chris Kerwin
Dunwell’s assertion that “the idea of experience. That wouldn’t be there in Head of Editorial, UK Publishing Jenny Potter
limitless leisure may sound attractive, a clone. UK Publishing Coordinator Eva Abramik
but [only] for people from very wealthy Contact UK.Publishing@bbc.com
www.bbcworldwide.com/uk--anz/ukpublishing.aspx
backgrounds”. The “very wealthy” people @HenryArrowsmith Surely the
I know are all entrepreneurs who work dog wouldn’t have exactly the same EDITORIAL BOARD
Andrew Cohen, Deborah Cohen, Michael Ewing,
80 hours per week inventing, creating, personality, however hard you tried? Julian Hector, John Lynch, Jonathan Renouf
helping to run companies or just trying The whole thing’s just... creepy.
to start one! The idea of limitless leisure Audit Bureau of Circulations
70,085 (combined; Jul-Dec 2013)
is abhorrent to them. Most successful
people have two or three ventures under Annual subscription rates (inc P&P):
Join the discussion at UK/BFPO £51.87; Europe & Eire Airmail
their belt and are always looking for the twitter.com/sciencefocus and £54.96; Rest of World Airmail £59.99.
next one to begin. Entitled? Hardly. facebook.com/sciencefocus
Jean Rigg, California BBC Focus Magazine is published by Immediate Media
Company London Limited under licence from BBC
Worldwide who help fund new BBC programmes.

Oops!
© Immediate Media Co Bristol Ltd 2014. All rights
ƀLJ"LJ1#!".LJ) LJ."LJ*#(%LJ#')(LJ reserved. Printed by William Gibbons Ltd.
given on p69 of the April issue should
be 11.92g, not 20g. Immediate Media Co Bristol Ltd accepts no responsibility
in respect of products or services obtained through
Rich people never do this, says Jean Rigg advertisements carried in this magazine.

JUNE 2014 / FOCUS / 17


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DISCOVERIES
News and views from the world of science
p22 CLIMATE AND
OUR FOOD
David Shukman
p24 MOUSE BRAIN
MAPPED OUT
Rodent research
p28
EDITED BY
JASON GOODYER

EXPRESS
YOURSELF
Researchers
on how global points to better chart the range
warming can a�ect understanding of of human facial
our food supply mammalian minds expressions

T HE BI G S T O RY

ICY MOON OF
SATURN COULD
HARBOUR LIFE
Discovery of
subterranean ocean
on Enceladus shortens
the odds on microbial
life existing there

M
OST SCIENTISTS
agree that if you’re
scanning the
Universe for signs
of extraterrestrial life, your
best bet is to look for water, a
key element of the primordial
soup that gave rise to life on
Earth. And now NASA’s Cassini
Below the icy surface
PHOTO: NASA

spacecraft has discovered of Enceladus lies an


one of the most promising ocean of liquid water

JUNE 2014 / FOCUS / 19


Discoveries

ANALYSIS
Dr Lewis
Dartnell
Astrobiologist at the University of
Leicester and author of Life In The
Universe: A Beginner’s Guide

THE NEW CASSINI


findings are very exciting.
It’s another stepping
stone on our way to
finding extraterrestrial life.
There are several locations in the
Solar System that astrobiologists
think are potential habitats. Mars is
obviously one of them, and there has
also been a lot of interest in Europa, a
moon of Jupiter, because there is an
underground ocean there. Then about
five years ago, out of nowhere, came
Enceladus, this tiny little snowball of a
moon that has fountains of water
gushing out of its surface.
When we analysed those fountains
– by flying through them with the
Cassini space probe and getting it to
Enceladus was discovered in hang its tongue out to taste that water
1789, but we knew little about
it until the Voyager mission – we realised that it was salty, and
that there were organic molecules in
there as well. The basic requirements
environments yet, finding evidence of NASA’s Jet Propulsion Laboratory. “As for life as we understand it are liquid
that Saturn’s icy moon Enceladus the spacecraft flies by Enceladus, its velocity water, organic molecules to build cells
harbours a large underground ocean. is perturbed by an amount that depends on out of, and some kind of energy
Researchers first theorised the existence of variations in the gravity field that we’re trying source, which Enceladus could have
a subterranean ocean on Enceladus in 2005, to measure. We see the change in velocity as as well. So it ticks all the boxes.
when Cassini discovered plumes of water a change in radio frequency, received at our We still have Cassini, which is
vapour and ice spewing from vents located ground stations here, all the way across the exploring Saturn and Enceladus, and
close to the moon’s south pole. Though Solar System.” we might discover further things with
Cassini is not able to land on the surface of The measurements made by Cassini during our measurements from that. But
Enceladus – and though there are no plans three fly-bys made between April 2010 and what people are likely to start talking
to send a spacecraft there in the immediate May 2012 suggest there is a large body of about more and more now is a
future – scientists can use measurements of water about 10km (6 miles) deep, beneath an dedicated Enceladus mission.
the gravity experienced by Cassini as it flies ice shell about 30 to 40km (19 to 25 miles) We might want to go back in a
past the moon to obtain reliable estimates of thick. Along with the discovery of salt and couple of years’ time, perhaps to fly
its internal structure. organic molecules in the vapour plumes through the fountains of water, collect
“The way we deduce gravity variations emitted from the moon, the findings point some of it and then loop
is a concept in physics called the Doppler towards Enceladus being among the most back to Earth for
Effect, the same principle used with a speed- likely places in our Solar System to host scientists to study it.
measuring radar gun,” explains Sami Asmar microbial life.

TIMELINE
How our knowledge of Enceladus has evolved over time
PHOTO: SUPERSTOCK, NASA X2, THINKSTOCK

1789 1847 1980 2005


Hanoverian-born British Herschel’s son John Voyager 1 finds Enceladus NASA’s Cassini
astronomer William names the moon has a diameter of just spacecraft flies within
Herschel discovers a Enceladus, a character 500km and orbits around 175km of Enceladus and
moon orbiting Saturn. from Greek mythology. Saturn’s diffuse E Ring, discovers plumes of
Three days later he which unlike the other water vapour issuing
discovers another rings is made up of from cracks in the
moon, Mimas. microscopic particles. moon’s frozen surface.

20 / FOCUS / JUNE 2014


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Discoveries

How global warming will


affect our food supply DAVID SHUKMAN
The science that matters

Droughts in the Amazon basin can


have far-reaching consequences

M
OST OF US never steaming upriver to collect shallow for the ships to carry supplies run too low. According
even think about the cargoes of soya. Grown on full loads. When they have to to the UN’s Intergovernmental
vulnerability of the food land where rainforest used sail half-full, the transport costs Panel on Climate Change,
industry until something to stand, the soya is shipped rise, adding yet more to the further warming is likely to
goes wrong. Extreme weather across the Atlantic to become price of the soya and everything reduce yields overall, with the
conditions in distant lands, such an ingredient in chicken feed. that relies on it. greatest risks in the second half
as a heatwave in Texas, can hike The year before, a drought had Looking ahead, basic biology of the century.
prices for a staple crop like damaged the crop so prices for might suggest a rising level of International trade has made
maize dramatically. It’s why soya had shot up, and that made atmospheric CO2 would be good food cheaper but also made
research into how climate British-reared chicken more for plants – growers pump the supplies more volatile – which
change could affect future expensive too. Later, in Belfast stuff into their greenhouses means that climate change
harvests is increasingly relevant. docks – one of the receiving after all. And indeed, a few is about much more than
Some years ago, in the ends of the trade – I watched crops in some regions may do warming. Just a thought for the
sweltering heat of the Amazon a dusty cargo of Brazilian soya better in coming years – and next time you look down at a
rainforest, I saw one of the coming ashore and learned the most adaptable farmers will plate of chicken.
most controversial elements how droughts in the Amazon quickly spot new opportunities.
of the international food could do more than cripple the But most plants will fail to
network first-hand. Giant harvest. A lack of rainfall can thrive when temperatures DAVID SHUKMAN is the BBC’s
ocean-going freighters were also mean the river becomes too become too fierce and water Science Editor. @davidshukmanbbc

a whale fossil. The new brew, finding this method too


THEY DID WHAT?! which has been named Bone
Dusters Paleo Ale, is said to
difficult, they found a sample
on a prehistoric fossil instead,
Beer made from taste ‘Belgian’. discovering a new subspecies of
PHOTO: GETTY ILLUSTRATOR: ADAM HOWLING

fossilised yeast yeast that they used to create a


How did they do that? tasty citrus-flavoured ale.
The brewers originally
wanted to collect yeast, the Why did they do it?
What did they do? microorganism needed for The aim was to get the public
A beer maker in Virginia, USA, brewing, from inside a piece of interested in palaeontology and
has created a drink from 35 amber, à la dino resurrection science – as well as making a
million-year-old yeast found on movie Jurassic Park. After refreshing pint, of course.

22 / FOCUS / JUNE 2014


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Discoveries

NEUROSCIENCE

1 MINUTE EXPERT Mouse brain wiring mapped


Nanodot
AKING THE LONDON A to Z seem highways and the major cities that they
What’s that?
This season’s
new must-have
fabric pattern?
Way o� the mark. Nanodots are tiny
M like a simple picture book, researchers
at the Allen Institute for Brain Science
have pieced together the first ever map
of a mammal’s neural network.
The Allen Mouse Brain Connectivity Atlas
link,” explains Caltech’s David Anderson.
“Smaller road networks and their
intersections with the interstates will be
the next step, followed by maps of local
streets in different municipalities. This
nanometre-scale structures that utilise shows the ‘connectome’, a kind of neural information will provide a framework for
the properties of quantum dots to wiring diagram, of the rodent’s brain. To what we ultimately want to understand:
confine magnetic or electrical fields to achieve this, researchers injected more ‘traffic patterns’ of information flow in
incredibly small areas. than 1,700 mice with genetically engineered the brain during various activities such as
viruses that could trace and illuminate decision-making, mapping of the physical
Right. So what are individual neurones. They then produced a environment, learning and remembering,
quantum dots? series of images of the organs at resolutions and other cognitive or emotional processes.”
They are essentially 50 times smaller than the diameter of a human The mouse brain atlas brings us a
semiconductor crystals with a size of hair and assembled the data. The resulting step closer to fully understanding the
around 2 to 10 nanometres across; 3D map contains more than 1.8 petabytes of complexities of the mammalian brain.
roughly equivalent to around 50 atoms. data, equivalent to 24 years’ worth of HD video. Researchers say that the next step will
Due to their small size, quantum dots “The atlas provides an initial road-map be to figure out more accurately how the
have properties that lie somewhere of the brain, at the level of interstate brain’s circuitry functions.
between larger semiconductors and
individual molecules.

So what can they


be used for?
They are currently being
developed for use in everything from
computer displays to storage media.
However, Israeli company StoreDot
recently demonstrated a battery based
on nanodot technology that it claims
can charge to full capacity in just 30
seconds. They also say their battery
PHOTO: ALLEN MOUSE BRAIN CONNECTIVITY ATLAS

is about five times more powerful than


regular batteries and so could be used
to make smaller power sources for
mobile devices.

Wow. When can


I get one?
The technology is still
in the development stages but
StoreDot hopes to release the battery Caltech’s atlas of
the neural pathways
commercially in late 2016.
found in mice

WHO’S IN THE NEWS? What did he do?


Had bees sting his penis
and scrotum along with
occurrence for Smith.
However, when a particularly
intrepid bee found its way into
painful area to be hit with
the excruciating venom was
the nostril, receiving an eye-
Michael 23 other areas of his body. his shorts and stung him on watering 9 out of 10 on the
Smith Deliberately. He then rated the scrotum, he was surprised pain scale. The scrotum and
A postgraduate the resulting pain on a scale that it wasn’t as painful as the penis came in at 7.3 and
student at New of 0 to 10. he expected. This made him 7 respectively, which is still
York’s Cornell wonder how the pain of stings very painful. The least painful
University Why did he do that? varies across the body. regions were the skull, toe and
As a researcher of bee upper arm, each scoring just
behaviour, stings are What did he find? 2.3. Still, we advise that you
presumably an everyday Surprisingly, the most don’t try this at home.
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Discoveries

10
DISCOVERIES THAT Night vision
contact lens
WOULD YOU LIKE to give yourself
night vision just by putting in a
pair of contact lenses? That’s the
promise of a light detector made of
the ‘miracle material’ graphene that’s
been developed at the University of
Michigan. The device, which senses
infrared radiation, is currently the
size of a fingernail but could be scaled
down and incorporated into a contact
The future of medicine: wearable lens or a mobile phone.
PHOTO: SEOUL NATIONAL UNIVERSITY, SCIENCE PHOTO LIBRARY, THINKSTOCK, BOB ELBERT, ALAMY, SUPERSTOCK, SHAWN MANSFIELD/UBC, GETTY, KANG LEE/MARIAN BARTLETT

Smart medical patches electronics integrated with nanoparticles

A MEDICAL PATCH could collect data made of silicon nanomembranes, a


on your health and deliver drugs into memory of gold nanoparticles and silica
your skin over long periods of time. nanoparticles loaded with drugs. Its
Scientists at Seoul National University, developers hope that, in future, a patch
Republic of Korea, have developed could help medics better understand Soon we could
all be able to
some of the ‘nanomaterials’ for the neurological disorders like heart failure, see in the dark
patch. They include a motion sensor epilepsy and Parkinson’s disease.

The airborne GPS system


Computer spots Resetting the
fake faces body clock
A COMPUTER SYSTEM at the HOW YOUR BODY clock reacts to
University of Toronto has proven changes in light and temperature
better at spotting faked expressions is controlled by an enzyme called
of pain than people. The simulated CK1epsilon. That’s the finding
emotion is hard for humans to of scientists at the University of
discern. After training they only Manchester, and it could lead to ways
Airborne GPS boosts had a 55 per cent success rate while of combating jet lag and minimising
weather forecasts the computer managed 85 per cent. the sleep disruption caused by night
The system could be used in airport shifts. CK1epsilon is a component of
security and the legal system, as well circadian clocks. In the study, mice
WE’VE ALL FOUND ourselves caught as for treating mental disorders. that lacked the enzyme adjusted to
in a rain shower, cursing the forecaster a new light-dark environment much
who said it would be sunny. Now, a faster than normal.
system developed by Scripps Institution
of Oceanography in San Diego promises
to improve weather models using GPS
receivers on commercial aircraft. The
system takes precise measurements at A. B.
different altitudes in the atmosphere, and
Which do you think is the real expression of pain?
could be especially useful for gathering
If you said image ‘B’, you’re correct!
data in hurricane-prone regions.

26 / FOCUS / JUNE 2014


Discoveries

WILL SHAPE THE FUTURE Sniffing out Transient


fake reviews materials
WHILE ONLINE SHOPPING AN LED LIGHT, complete with
has boomed, so has the number of wiring, has been made to dissolve
fake reviews – sometimes paid for in a drop of water. It’s the first step
by unscrupulous companies. Now towards ‘transient materials’ that
there could be a way of detecting melt on command. Applications
reviews that aren’t what they seem, could include credit cards that
thanks to Yan Sun at the University self-destruct, non-polluting climate
of Rhode Island. She developed a sensors or medical devices that melt
Look on the cloudy side computer model that looks for an away inside your body.
ordered pattern underlying ratings, A team at Iowa State
THE LACK OF sunny weather on our indicating they might include fakes. University has designed
islands has always been one of the transient electronic
drawbacks of solar power as a reliable components including
energy source. But now, the UK’s resistors and capacitors.
National Physical Laboratory has come
Iowa State’s Reza
up with organic photovoltaic cells that Montazami examines
are more efficient than regular solar a degradable
panels in cloudy conditions. The thin, antenna
flexible sheets of material could in future
be made into clothing which could
charge your phone and other gadgets.

Greener Designer
paper yeast
WHEN WOOD PULP is processed, A YEAST CHROMOSOME has
a component of the cell walls known been designed in a computer and
as lignin must be removed, requiring successfully incorporated into
chemicals and a lot of energy. But living yeast. It’s the first synthesis
GM trees could produce more of a eukaryotic chromosome – the
eco-friendly paper. Scientists at structure that carries genes in the
the University of British Columbia nucleus of plant and animal cells.
modified lignin to make it easier to The synthetic chromosome, one
break down, without weakening the of 16 chromosomes in yeast, was
tree as earlier efforts had. engineered with new properties.
In future, scientists hope to go
Genetically engineered further by developing synthetic
weak points in lignin make yeasts that could manufacture
it easier to break down
rare medicines or produce more
efficient biofuels. Around a third
of yeast’s 6,000 genes are shared
with humans. The research was
led by Jef Boeke, director of In future, artificial yeast
NYU Langone Medical Center's strains could be tailored
Institute for Systems Genetics. to produce medicine

JUNE 2014 / FOCUS / 27


Discoveries

GRAPHIC SCIENCE
Seeing research differently EMOTIONS ARE WRITTEN ALL OVER OUR FACES

Happy Happily disgusted Disgusted Disgustedly surprised Surprised

Sadly surprised Sad Sadly angry Angry Fearfully angry

HOW ARE YOU feeling right now? Happily distinct human facial expressions, including to map emotional responses in the brain and
disgusted, perhaps? How about sadly those corresponding to the seemingly potentially aid the diagnosis and treatment
angry? Researchers at Ohio State University contradictory feelings mentioned above. of conditions such as post-traumatic stress
have used computer modelling to identify 21 They hope the work will be useful in helping disorder (PTSD) and autism.

ZOOLOGY exposed flies to images of than we blink our eyes, which is


approaching predators and faster than we ever imagined.”
Swat captured their responses
using high-speed video
During the acrobatic
manoeuvres the flies can roll

team cameras running at 7,500 more than 90 degrees, and at


PHOTO: OHIO STATE UNIVERSITY, FLORIAN MUIJRES

frames a second. times almost fly upside down.


“Although they have been Dickinson now wants to figure
described as swimming through out how the flies are capable
FRUIT FLIES CAN be pretty the air, tiny flies actually roll of such complex movements.
tricky to swat. Now, a team at their bodies just like aircraft “A fly with a brain the size of
the University of Washington in a banked turn to manoeuvre a salt grain has a behavioural
has figured out why: they away from threats,” said study repertoire nearly as complex
employ evasive manoeuvres lead Michael Dickinson. “We as a much larger animal such
reminiscent of those carried out discovered that fruit flies alter as a mouse,” he said. “That's an
by fighter pilots. Researchers at course in less than one 1/100th interesting problem from an Fruit flies in training for this year's
the University of Washington of a second, 50 times faster engineering perspective.” Farnborough International Airshow

28 / FOCUS / JUNE 2014


Comment

INSIDE SCIENCE

ROBERT MATTHEWS
It may not have held up, but the Steady State theory was a thing of beauty

HE DEMISE OF something beautiful is

T
an odd thing to celebrate. It’s even harder
to understand if that something is a
scientific theory – for how can a theory
be ‘beautiful’? As with works of art,
scientific beauty is a bit subjective. But I’d argue
only total philistines could fail to see the beauty of
a theory that died exactly half a century ago: the
Steady State model of the Universe.
Born in the mid-1940s in Cambridge, it was the
brainchild of some of the most original scientists
of the last century, including Fred Hoyle – the
greatest astrophysicist of his day. In essence,
they argued that the Universe wasn’t created in
some messy ‘big bang’ billions of years ago (to
use the derisive term Hoyle himself coined).
Instead, it has existed forever, its expansion
propelled by what we’d now call dark energy,
which also created matter to keep the density
of the Universe constant – and thus forever in
a ‘steady state’.
Even at the time, the Steady State theory
generated controversy – stoked by personality
clashes between its creators and their academic
rivals. In the end, its critics proved right. As ‘How
do we know...’ describes on p90, in June 1964
two physicists at Bell Laboratories in New Jersey
detected radiation from space with exactly the
properties expected of the cooling embers of that
messy Big Bang the Steady State model rejected.
Yet not everyone celebrated the demise of
the Steady State theory. The late, great British
cosmologist Dennis Sciama put it best, saying
the theory had “a sweep
and beauty that for some
unaccountable reason
“I’d bet serious on the grandest scales, it looks the same at all points and in all directions.
But the Big Bang universe lacks one key symmetry. On the grandest
the architect of the money on the timescales, it’s not the same. It lacks temporal symmetry. This is what
Universe appears to makes the Steady State universe achingly beautiful to theoreticians:
have overlooked”. Steady State theory it’s ‘maximally symmetric’. On the largest scales, it looks the same in all
With pretty much
everyone now believing
emerging as the directions – and at all times. Amazingly, all its properties can be worked
out purely from this fact; you don’t need to assume Einstein’s theory of
there was a Big Bang 14 perfect description gravity, or anyone else’s, to tell what it’s like.
billion years ago, such Too bad, then, that it’s wrong. Or is it? Half a century after its demise,
hand-wringing may sound of the Multiverse” there’s huge interest in the idea that – on the grandest scales – our
ILLUSTRATOR: JAN VAN DER VEKEN

quaint. But Sciama’s Universe is just a speck in a truly infinite Multiverse, with the Big Bang
aesthetic arguments still hold up. Most obviously, the Steady State theory just one of a series stretching back into the infinite past. I’d bet serious
didn’t give rise to awkward questions about what existed ‘before’ the money on the Steady State theory emerging as the perfect description
Universe. Less well known is the fact that the Steady State model had a not of our clunky Universe, but of the Multiverse, in all its maximally
key feature of beautiful things: symmetry. symmetric beauty.
Most people regard symmetry merely as some kind of appealing Sadly, I probably won’t be
regularity. But to theoreticians, it’s far more profound. It gives them ROBERT MATTHEWS is Visiting
around in 2064 to collect my
unchanging properties they can rely on to build models of reality. For Reader in Science at Aston winnings. But remember - you
example, they regard the Universe as having spatial symmetry; that is, University, Birmingham heard it here first. �

JUNE 2014 / FOCUS / 29


Discoveries

MEDICINE
ENGINEERING

Dutch woman gets Hear no evil


a 3D-printed skull

D
UTCH SURGEONS HAVE University Medical Center
replaced a large section Utrecht, the top of the patient’s
of a woman’s skull with a skull was removed and replaced
3D-printed replacement, with a custom-made plastic
saving her life in what is being copy that fitted neatly with the
hailed as the first successful rest of her skull.
operation of its kind. The operation was a
The 22-year-old patient resounding success. “The
suffered from a rare disorder patient has fully regained her
that caused her skull to grow vision,” said Verweij. “She has
extra bone. This applied extra no more complaints, she has
pressure to her brain, giving the gone back to work and there
woman severe headaches and a are almost no traces that she
gradual loss in vision. had any surgery at all.” Scientists at Duke University have invented a practical sonar cloaking device
If left untreated, the The team now hopes that
condition would eventually the technique will help to IT’S EVERY SUPERVILLAIN’S simple. I promise you it’s
have killed her. But in a 23-hour reconstruct skulls that have dream: a device for hiding a a lot more difficult than it
operation led by neurosurgeon been severely damaged in secret underwater lair from looks,” says Steven Cummer,
Dr Bon Verweij at the accidents or by brain tumours. the prying ears of military professor of electrical and
sonar. Well, that dubious computer engineering
wish may soon become a at Duke. “We put a lot of
reality. Engineers at Duke energy into calculating
University have created how sound waves would
an acoustic cloak that can interact with it.”
effectively reroute sound To give the illusion that it
waves around any object to isn’t there, the cloak alters
create the sonic impression the sound waves’ trajectories
that there is nothing there. to match what they would
The resulting device is look like had they reflected
a complex pyramid-like off a flat surface.
structure constructed of The technology could be
perforated plastic plates. used in sonar avoidance or in
The 3D-printed prosthetic “The structure that we controlling the acoustics in
skull that saved a Dutch
woman’s life
built might look really concert halls, Cummer says.
PHOTO: DUKE UNIVERSITY, ZACK VEILLEUX/THE ROCKERFELLER UNIVERSITY, PRESS ASSOCIATION

BIOLOGY the characteristic smell of a


New research suggests the human nose
rose has 275 components. To is far more sensitive than we thought

You smell good! overcome this, Keller compiled


a shortlist of 128 odour
molecules that are responsible
for powerful scents such as
AS ANYONE WHO has caught “The message here is that orange, anise and spearmint,
a whiff of a cheesemonger’s we have more sensitivity in and mixed these molecules
apron knows, the human sense our sense of smell than we give in a variety of proportions.
of smell can be pretty sensitive. ourselves credit for. We just He then presented
In fact, according to a study don’t pay attention to it and volunteers with three vials,
carried out at The Rockefeller don’t use it in everyday life,” two of which containing
University, the humble human says Andreas Keller, who led identical mixes, and asked
schnoz is able to detect more the research project. them to pick the odd one
than 1 trillion odour mixes. Scents are composed of out. By analysing the data,
That figure far outstrips the complex mixes of molecules, the researchers were able to
generally accepted number of making them incredibly calculate the total number of
just 10,000. difficult to study. For example, distinguishable mixtures.

30 / FOCUS / JUNE 2014


Comment

EVERYDAY SCIENCE

HELEN CZERSKI
The curious tale of the cyclist, the scorpion and a beam of ultraviolet light

OU MAY THINK that cyclists and

Y
scorpions have nothing in common.
But you’d be wrong. Both have a bit
more to their appearance than meets
the eye. Last week, I was peddling to
work on a dull, grey day and I stopped at traffic
lights behind about 20 other cyclists. Between
them, they were wearing a huge variety of
colours, but five or six of them popped out of
the scene almost as if they had spotlights on
them. I found myself wondering why yellow
high-visibility clothing is so much brighter than
everything else. After all, it’s just a colour, isn’t it?
Our world is flooded with oodles of light, at
least during the day. But what we see is only
what’s left over after its journey has extracted
a toll. As light travels through the atmosphere
and bounces off the objects around us, the
environment is chipping away at it. Everything
that the light passes through or reflects off
will absorb and scatter some wavelengths. My
notebook is red because its cover absorbs every
other colour, so red is all that’s left when that
light reaches me. The character of the light that
we see is just what’s left over after all those
subtractions. In theory, there’s a fingerprint there
from every part of its journey since it left the Sun.
So, back to the high-visibility jackets. What was
bothering me is that they were so much brighter
than everything else, even though that light had
been through a similar series of subtractions to
everything else around them. But the high visibility
dye has an extremely clever trick up its sleeve.
It is taking advantage of
something that I couldn’t
see in that scene:
“Cyclists are letting other things. If you shine UV light on them in a dark room, you’ll see the
glow. This is fluorescence.
ultraviolet light or UV. me detect UV light. I love this idea because it means that the cyclists are letting me detect
The lenses of our eyes UV light. If their jackets are glowing, UV must be there, even though I
protect us from it, but If their jackets are can’t see it. A bit further down the road, I remembered that this happens
quite a lot of UV passes
through clouds, so even
glowing, UV must be in the natural world too. Ask the experts how to find a scorpion, and
they’ll tell you to go out in the desert at night with a UV light. Scorpions
on a dull day there’s there, even though I glow blue-green in UV, because they have fluorescent molecules built
quite a bit of it about. The
dye molecules absorb
can’t see it” in to their exoskeleton. No-one really knows why, but it’s thought that
it might help them find dark places to hide, especially around twilight
high-energy UV light and when the proportion of UV light is higher. If that’s the case, their whole
ILLUSTRATOR: CIARA PHELAN

emit lower-energy visible light. They are taking the light we can’t see and exoskeleton is a UV detector, shifting invisible light down into the colour
turning it into light that we can see. The reason high-visibility clothing range that the scorpion can see. We tend to assume that we can see
looks like it’s glowing on a dull day is that it really is – it has an extra everything that there is, but the
source of energy. There is still no such thing as a free lunch, but the cost world is richer than that.
comes in a region of the spectrum that we don’t care about. This is why Next time I see a high-visibility
DR HELEN CZERSKI is a physicist,
high-visibility jackets are no good in the dark – there’s no natural UV light oceanographer and BBC science jacket shine out of a dull scene, I’ll
around to give them that extra glow. It’s not just jackets either – these presenter who appears regularly remember it’s a sneak peek into the
dyes are used in laundry brighteners and highlighter pens and all sorts of on Dara O Briain’s Science Club world of invisible colours. �

JUNE 2014 / FOCUS / 31


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See Britons as you have never seen them before in Britain: One Million
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© The Trustees
of the Natural
History Museum,
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T
ravel back in time long techniques and life-size models
Archaeologists excavating on the Norfolk coast discovered
before the Romans, bring rarely seen specimens to life
some of the oldest human footprints in the world. The humans
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come face to face with your humans came and went from
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© The Trustees of species Homo antecessor.
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© The Trustees of the
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London 2014. 40,000 years ago
Homo sapiens
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world, you will be surprised by details of their behaviour and way rhinos and giant deer. From
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humans who inhabited ancient archaeologists, palaeontologists Neanderthals in Europe, to People abandon Britain
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Comment

INTO THE FUTURE

STEPHEN BAXTER
We’re a proud tunnelling nation, but a gravity train remains a distant dream
AY 2014 WILL be the 20th

M
anniversary of the opening of the
50km- (31-mile) long Channel Tunnel.
In Britain, ambitious tunnelling
projects go back a long way.
The Channel Tunnel itself was first proposed
in Napoleonic times. The Victorian era saw
Isambard Kingdom Brunel and his works under
the Thames, and the great burrowing that created
the London Underground. Today the Crossrail
project is underway in London and its surrounds.
By the time of its completion in 2019, 42km (26
miles) of new tunnels will have been built.
Even more ambitious schemes have been
put forward. How about a transatlantic tunnel?
Serious proposals date back to 1888. Perhaps
going via stations in Iceland and Greenland,
such a tunnel could vastly reduce the need for
transatlantic airfreight. But journey times could
be long, and since more than one bore would be
required for ventilation purposes – the Channel
Tunnel actually consists of three tunnels - the
cost would be eye-watering.
Perhaps modern engineering techniques would
help. US entrepreneur Elon Musk is proposing a
‘Hyperloop’ to link Los Angeles to San Francisco.
Passengers would ride pods through a vacuum
tube, propelled by magnetic fields. Could such
a system be built to span the stormy Atlantic,
running along the seabed? London to New
More ambitious still, the ‘gravity train’ was York by train; the
Victorians dreamed
devised as long ago as the 17th Century by British of transport like this
scientist Robert Hooke, who presented the idea in
a letter to Isaac Newton,
originator of the theory of
gravity. In principle the
“The ‘gravity train’ considerations. Shallow tunnels might be possible, but the rising heat and
pressure inside the Earth would soon make deep tunnels impracticable.
scheme could not be was devised as Even so, the idea has been seriously presented a few times, such as to
simpler. To connect London the Paris Academy of Sciences in the 19th Century.
to New York, say, you long ago as the 17th Maybe the idea is still ahead of its time. The Moon, smaller than the
would drill a straight-line
tunnel direct from one city
Century - the scheme Earth, and with an interior much cooler and more stable, might be a
candidate for such a scheme – although a ride between any two points on
to the other, passing under could not be simpler” the Moon will take longer than 42 minutes because of the Moon’s lower
the Earth’s curved surface. density. Mars too is cooler and more stable than Earth and might be
The great benefit of the scheme is that running a train through it would suitable for the technology. Ceres, the largest of the asteroids and a rigid
be effectively free. If you could eliminate friction, perhaps by running ball of rock and ice, would be another possibility.
through a vacuum like the Hyperloop, you let gravity do the work of pulling Perhaps future lunar inhabitants will grumble their way on daily commutes
ILLUSTRATOR: ANDY POTTS

the train down the tunnel, accelerating it to its fastest speed and deepest from the craters Tycho to Copernicus, having no idea that their superfast
point at the halfway mark, then slowing it as it rolls up the ‘slope’ at the transport system was the idea of
other side. How long would the journey take? As Hooke himself showed, a contemporary of Newton – just
it’s an oddity of the proposal that, if the planet has a uniform density, as we grumble about delays in the
STEPHEN BAXTER is a science
then no matter which two points are connected by the tunnel – even if it fiction writer whose books Chunnel, forgetting what a miracle
passes through the centre of the Earth itself – the journey time is always include The Science Of Avatar the system would have seemed to
the same, a little over 42 minutes. Needless to say there are practical and the Northland series engineers like Brunel. �

JUNE 2014 / FOCUS / 37


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HOW
SCIENCE
WILL HELP
YOU LIVE TO

AND BEYOND...
We’re on the cusp of a medical
revolution. Lilian Anekwe reveals
how studying the human genome
will radically extend
your lifespan

ILLUSTRATOR: JUSTIN METZ

JUNE 2014 / FOCUS / 39


HE A LT H

HAT IF YOU could live past 100 Venter’s company, HLI, will start by

W
years of age? Would you want to? buying two cutting-edge gene sequencing
It’s a question we might all need machines from UK company Illumina
to start thinking about. In recent with its investment money, and sequence
months some of the world’s the genomes of 40,000 people, eventually
highest-profile pioneers have announced ramping up to 100,000 people a year. At
they are turning their attention to finding the same time HLI hopes to catalogue
the genes that could make us live forever. the bacteria that live in and on the
Their ambition: to hunt down the illnesses human body in an ecosystem known
that affect us in old age. as the microbiome, and sequence the
The forerunner in this race to help metabolome – the genetic information
us live longer has to be Craig Venter: about the biochemicals in the body.
the geneticist, entrepreneur and It’s an enormous undertaking but
philanthropist behind the Human Genome Craig Venter is confident this big genetic
Project, whose own genetic information data approach will answer the biggest
was among the first ever published in questions about human life, and death,
2011. In March this year, he announced ushering in a new age of medicine. “We’re
PHOTO: SCIENCE PHOTO LIBRARY X2, GETTY, GOOGLE, CORBIS X2, ALAMY, THINKSTOCK, NEW YORK GENOME CENTER

his latest project would use $70 million of likely to gain a better understanding of
venture capital to set up a new company human lifespan with this approach,”
called Human Longevity Inc (HLI). he says. “But if all we could learn about
But Venter isn’t alone in his ambitions. was the sequence of the genome I would
In September 2013, Google CEO Larry not waste my time or the money. The
Page announced he had appointed potential is to truly understand our
Art Levinson, chairman of Apple and genetic propensity for health and disease.
biotechnology company Genentech, We think we can answer for the first time
as CEO of Google Calico (California in history the question everybody asks:
Life Company). Calico has the what’s nature and what’s nurture?”
straightforwardly ambitious remit of
improving human health and well-being, Science could help you celebrate such a landmark
and solving the challenge of ageing and
associated diseases.

A GIANT UNDERTAKING
Calico and HLI are fledgling companies
with bold promises, especially when
you consider that only a handful of trial
patients have received treatment based
on genomic research. So it begs
the question: how will
they stop ageing? And
what will treatment
look like?

The genomic pioneers,


from left to right: Art
Levinson, Larry Page and
Craig Venter
HE A LT H

WHAT WILL THE NEW AGE


OF MEDICINE LOOK LIKE?
The amazing therapies on the horizon that will help you live longer
“We can answer
for the first time in STEM CELL THERAPIES
As we age our stem cells are
history: what’s nature depleted and degraded. Sequencing

and what’s nurture?” data could be used in the emerging


field of regenerative medicine. This
Craig Venter, biologist and entrepreneur, involves using stem cells to repair
co-founder of Human Longevity Inc aged tissues, as well as repairing
damage to our organs caused by
degenerative diseases or physical
damage to our bodies as we age.

“It isn’t a coincidence that these


ventures have launched within months
PERSONALISED
of each other,” says Dr Scott Lippman,
MEDICINE
Genomic data could tell us
director of the Moores Cancer Center at
who will respond to a drug
the University of California, San Diego –
and why certain drugs work
where every cancer patient who consents
better for some people than
will have their genomes and tumours
others. It could allow doctors
sequenced by HLI.
to choose the most e�ective
Since the first human genomes were
drugs for patients with the least
sequenced in 2011, the field has progressed
side e�ects.
at a rapid pace and now cancer researchers
are at the cusp of “the next frontier in
science”, explains Lippman. “Right now PREVENTATIVE MEDICINE
we are in a period that is going to be If you could find out how long
transformational for cancer, in a similar you have left, would you want
way that the ’90s were for the internet. to know? You could discover
We understand the genome, and the what your genome (human DNA
technology means sequencing on this scale sequence, pictured) says about
can be done quickly and more cheaply your risk of cancer and have an
than before. What used to take us 15 to optimum longevity package and
20 years we can now do in a year or two. customised preventative advice to
The cancer field is moving very quickly help you make a century.
and this is just the tip of the iceberg.”
According to the World Health
Organisation, cancer was the FAECAL TRANSPLANTS
The bacteria in our gut (pictured)
changes with age. There’s a theory,
however unappealing you might
find it, that suggests we can use
a microbiome analysis to identify
someone with ‘young’ gut bacteria,
and transplant poo - which contains
their gut bacteria - to rejuvenate the
microbiome of an older person.

BIOINFORMATICS
Researchers at IBM and the New
York Genome Center (pictured) are
designing computer programs that
cancer doctors can use to upload
an analysis of your genes and
mutations. The software would
then study your genetic code and
provide a shortlist of relevant drug
The complex array of channels of a genome sequencing options that will work best for you.
machine, which can decode human DNA

JUNE 2014 / FOCUS / 41


5THINGS YOU CAN DO TO START LIVING TO

Masa Narita of Osaka, Japan turned 100 in The family of 101-year-old Tomiko Kadonaga, Now 103, Fauja Singh became the first ever Dorothy Newell celebrates her 100th birthday
February; keeping her social life going has a Canadian, say that the secret to her long 100-year-old to finish a marathon. The event last February in Detroit; eat a balanced diet
helped make her a centenarian life has been her sense of positivity was the Toronto Waterfront Marathon in 2011 and you could make it to this ripe old age

BOOST YOUR STAY POSITIVE GET MOVING EAT A BALANCED DIET


SOCIAL NETWORK Your personality could be We all like to laze around a bit, Studies of rats fed a calorie-
This doesn’t necessarily important in ageing. Studies but researchers are saying restricted diet have found this
mean signing up for a new of the children of centenarians that inactivity is drastically can double their lifespan. But
Facebook account, but having found they are more extroverted reducing our lifespan. Being this hasn’t been conclusively
a strong social network of and less neurotic than others. sedentary has been linked proven in humans. In
friends and family around Similarly, a study in the journal with diabetes, obesity, heart fact, studies of Ashkenazi
you to provide support JAMA Psychiatry found that disease and cancer - all Jewish centenarians in the
during stressful situations in people who feel they have a big killers of people in their US found they didn’t stick
life is vital to make it to the sense of purpose in life tend old age. A study in 2011 to any particular diet and
big one hundred. One study to live longer. And people who estimated that our lives are were just as likely to be
by researchers at Brigham feel that ageing gives them about 22 minutes shorter for overweight as their shorter-
Young university found that more time to do meaningful every hour we spend sitting living peers. In other regions
people with a solid group things, like spending time with watching television after where centenarians are
of friends are 50 per cent family or helping others, lived the age of 25. So why not common (Okinawa, Japan,
more likely to survive at longer, according to research get o� the couch and try and Sardinia, Italy) the
any given time than those by the Longevity Project at reading the rest of this diet includes little, if any,
without one. Stanford University. article standing up? processed food.

third highest global killer in 2011, The sequencing of genes will be just That has been helpful to a limited
causing one in seven of all deaths one battlefront in the war against extent, but it’s been hard to make
worldwide, and for the most part cancer ageing. Dr Razelle Kurzrock, director of great leaps using these techniques,”
is a disease associated with old age. HLI personalised cancer therapy at Moores he says. “That’s because 100 lung
plans to use the genome data it generates Cancer Center, sees other ways that cancer patients may all have different
from sequencing to identify and analyse HLI’s genome catalogue could change abnormalities that drive the growth
the genes involved in cancer and find medicine. “At the moment we are lumping of their cancer. Only a small fraction
potential new treatments. people with different cancers together. will respond to a treatment.

42 / FOCUS / JUNE 2014


HE A LT H

100 NOW “What used to take


us 15 to 20 years we
can now do in a year
or two. The cancer
field is moving
very quickly”
Dr Scott Lippman, director of the Moores Cancer
Center at the University of California, San Diego

Dr Scott Lippman thinks that technology has made it possible


to usher in an era of genomic medicine

influence all of medicine. The potential


is enormous.”
The hope is that what HLI learns
about cancer can be applied to diabetes
and obesity, heart and liver diseases, and
dementia. But finding treatments for these
illnesses may not be enough to increase
human longevity. After all, it’s estimated
that even if we found a cure for cancer this
would only increase the average human
lifespan by a few years – before people die
of a different disease.
This is why, according to Craig Venter,
the goal of solving one illness – even one
Seven hours’ kip a night is the optimum
which is as big a threat to human health as
amount to live longer - maybe think about cancer – is not HLI’s ultimate aim. “While
resetting that alarm clock we’re all going to die of something, your
age is your number one risk factor for
...AND SLEEP every disease,” says Venter. “In the last few
Around seven hours a night decades the average human lifespan has
could be the best amount for increased. Fewer people are dying from
a longer life. Researchers cancer and heart diseases, but more are
at the Scripps Clinic Sleep living longer with illnesses like dementia
Center in California found that impact quality of life. I wouldn’t
a U-shaped relationship necessarily call that a healthy lifespan. So
between the average number the goal is not just to extend lifespan – it’s
of hours of nightly sleep and to extend the healthy human lifespan.”

PHOTO: GETTY X3, ALAMY X2, SCIENCE PHOTO LIBRARY X3, SUPERSTOCK
death rates in a study of
more than a million American
adults. People who slept FAULTY GENES
between 6.5 and 7.5 hours a The fundamental mechanisms controlling
night lived the longest, and human ageing are complex. What we know
people who slept for more about the genetics of ageing comes from
than eight or less than 6.5 studies of families, twins and centenarians
hours a night didn’t live – people who live beyond 100 years.
quite as long. Longevity tends to cluster within families,
and parents and siblings of centenarians
have a greater likelihood of living to an
advanced age than other people.
“In the past we have not been able From studying these families and
to differentiate which patients will searching the genome for small genetic
respond to treatment or which will have variations that occur more frequently
side effects. Genomics should allow in people with a particular disease,
us to personalise therapy according to researchers have identified targets like
Cancer is an age-related disease and comes in many
people’s genetic profile – this is the basis apolipoprotein E, a protein involved in forms – it’s hoped that researching the genetics of ageing
of personalised therapy. It’s my belief lipid metabolism. A genetic variant in will help tackle various types of cancer. From top to
that personalised therapy will spread to the apolipoprotein E gene (ApoE E4) bottom: lung, skin, breast and prostate cancer cells

JUNE 2014 / FOCUS / 43


SHOULD WE BE TRYING “People smoke
TO LIVE TO 100?
heavily and still
We asked two experts to argue
the ethical case for longevity
make it to 100. Is
this luck? I very
much doubt it”
Dr Razelle Kurzrock, director of personalised
cancer therapy at Moores Cancer Center
Dr Kurzrock believes our genes plays an important role in
determining how long we’ll live

is the major identified risk factor has huge potential for ageing. It’s an ideal
for late onset Alzheimer’s disease. process for large-scale analysis like Human
With a rising population putting pressure
By manipulating these kinds of genes Longevity Inc is proposing.”
on resources, is it right for us to live longer? biologists have been able to extend the
lifespans of mice by as much as 50 per
cent. These genetically modified mice live A BIG DATA PROJECT
FOR MANY DISEASES survival rates longer, degenerate slower and develop It takes a lot of vision to see how the
have already increased dramatically, diseases later. building blocks of our genes, bacteria
which Dr João Pedro de Magalhães, We still don’t know if genes identified by and metabolites (sequences of four DNA
from the integrative genomics of ageing the HLI sequencing could be manipulated elements tens of thousands of lines long)
group at the University of Liverpool in humans, but Dr João Pedro de could control something as complex
describes as “one of the greatest Magalhães, from the integrative genomics as ageing. So the sheer scale of the
achievements of technology”. of ageing group at the University of HLI project may make it easier to find
“I don’t think leaving people to die just to Liverpool, says the HLI data will provide target genes, says Dr Leonard Guarente,
control overpopulation is ethical. If people a good place to start finding out. “In professor of biology at MIT’s Glenn
are healthy they will choose to live as long mice we can retard all aspects of ageing – Laboratory for the Science of Aging.
as they can, that’s human nature,” says molecular, cell, longevity and disease – by “If you have one or two genes that are
de Magalhães. “There may be a sweet genetic manipulation. We don’t know for important for ageing you want them
spot, an optimum lifespan where we can a fact that it’s possible in humans but in to stand out,” he says. “So there has to
enjoy longevity, but not cause societal my mind there’s no reason to think it’s not. be some element of scale to be able to
problems. It wouldn’t be without issues Sequencing is the place to start. Genomics find them. What these gene hunters
in some countries with overpopulation
and a depletion of resources. But it’s not
true that the population will necessarily
explode. In terms of population growth the
PHOTO: THINKSTOCK, SCIENCE PHOTO LIBRARY, DAVID AHNTHOLZ, CORBIS

number one factor isn’t how long people


live, it’s how many babies they have. The
countries with the fastest population
growth are not the same countries where
people live a long time.”
Stopping ageing isn’t enough on its own,
says Dr Alex Zhavoronkov, director of the
UK-based think tank the Biogerontology
Research Foundation and author of The
Ageless Generation: How Advances In
Biomedicine Will Transform The Global
Economy. “The only way to ensure we
don’t go bankrupt is to increase people’s
productive longevity,” he says. “We don’t
have an option or an alternative. If we don’t
act quickly to extend healthy productive
longevity in the next 20 years there will be
a major economic collapse - much worse
than global warming or the depletion of A sequence of genes is marked as part of research into cancer at the Imperial Cancer Research Fund, London. The aim is to be able
fossil fuels.” to ‘switch on’ genes that will help the body destroy cancer cells, a goal that could be helped by the likes of Human Longevity Inc

44 / FOCUS / JUNE 2014


HE A LT H

Craig Venter is a firm believer that gathering as much data as possible is the key to teasing out the secrets of ageing from the human genome

are bringing to the table is the technology But Dr Kurzrock is convinced that the And Venter says success or failure of
to be able to analyse big data.” most revealing insights will come from HLI won’t change his approach to life –
Others are not so sure. Professor Paul comparing the genome sequences of her however long he lives for. “Despite what
Pharoah, director of Cancer Research UK’s patients at the Moores Cancer Centre with people think about this whole enterprise
genetic and molecular epidemiology unit healthy people. “In my work I’ve seen I am not in this to live longer or forever. I
at the University of Cambridge, questions people in their 30s and 40s who smoke and treat every day as a gift and a challenge.
HLI’s macro approach. “I’m not sure doing who already have advanced lung cancer, I like to act as if I’m going to live forever,
things on such a grand scale is the best while other people smoke heavily and but I treat each day as if I may not and try
way. There’s an awful lot of people doing still make it to 100 in robust health. Is this to live it to the fullest. But that’s more of a
tumour sequencing studies and looking at luck? I very much doubt it.” hope than a prediction.” �
the associations between cancer and ageing,” Craig Venter firmly believes his
he says. “What are they [HLI] doing, and approach will drive this area of research
what do they know that no one else knows?” further than ever before and is prepared Find out more
There is a limit to how much our genes to take a huge, calculated gamble on Listen to Prof Richard
can tell us about ageing because whether the success of his venture. “In the last Dawkins discuss genetic
we get illnesses and how long we live 15 years there have not been that many science in Age Of The
isn’t purely controlled by our genes – our breakthroughs that have changed Genome. http://bbc.in/Js7BfX
environment plays a big part, as do our medicine. [But with this] I believe we can
lifestyles and good old luck. make giant leaps. If we don’t have very
It’s too early to know what secrets substantial breakthroughs in preventative
HLI has tapped into by hacking human medicines I will be very disappointed. LILIAN ANEKWE is consumer health editor for
genomes for the last several months. But the odds of that happening are low.” the weekly medical journal the BMJ

JUNE 2014 / FOCUS / 45


F LY ING S OLO

UNDER
PRESSURE
We’re rewriting the rules of chemistry with sheer
force to turn everyday substances like salt into
remarkable new materials. Michael Banks
reveals the pioneering labs making it happen PHOTO: SCIENCE PHOTO LIBRARY

JANUARY 2014 // FOCUS


JUNE 2013 FOCUS // XX
49
M AT ER I A L S S CIENCE

ALT IS VITAL for human life. In (its charge is –1). So sodium happily gives away

S
our bodies this common ingredient an electron while chlorine happily takes it. The
regulates the exchange of water result is a compound that’s neutral in charge and
between cells. Made up of sodium therefore chemically stable, meaning that it cannot
and chlorine, it plays a key function decompose back into the individual elements or
in the heart, nerve impulses, and into any other compounds. At least that’s what we
the digestion of body-building thought until now.
proteins. Given salt’s abundance
in nature and how much we eat
every day, you might think that we CHEMISTRY REWORKED
know almost everything there is to find out about Last year, scientists in China, Russia and the US put
the material that has the chemical formula NaCl. tiny crystals of salt under huge pressures – a burden
But you’d be wrong. an order of magnitude greater than the pressure at Salt’s (NaCl) structure, its
‘unit cell’, is a basic cube
It was commonly thought that NaCl was the the bottom of the ocean (see ‘Feeling the squeeze’,
shape, which contains the
only compound that could be created out of its p53). What they found was totally unexpected: sodium and chlorine ions
constituent parts of sodium (Na) and chlorine (Cl). the material began to form so-called ‘forbidden
The laws of chemistry reflect that compounds compounds’ – ones that experimentalists thought
tend to form from the strongest bonding possible. did not even exist. “This work will change the way
For example, in its chemical make-up, sodium has chemistry is taught and used,” says Professor Artem
one electron that it wants to lose – having a charge Oganov from the State University of New York, a
of +1 – while chlorine has a space for an electron lead author of the story.

50 / FOCUS / JUNE 2014


M AT ER I A L S S CIENCE

Indeed, some interesting structures emerge as


a result. One product of putting salt under high
pressure is Na3Cl. Normal salt is a very bad conductor
of electricity. But this new compound is made up
of alternating layers of NaCl and pure sodium. The
atom-thick sheet of sodium is very similar to the
two-dimensional structure of graphene, and could
make for a very good conductor of electricity at

“This work will change


the way chemistry is
taught and used”
Prof Artem Oganov from the State University of New York

room temperature. Graphene, the so-called ‘wonder


material’, which is currently finding a myriad
of applications, could have new competitors.
Although physicist Alex Goncharov from the
Carnegie Institution of Science, Washington,
adds that while there might not be any
immediate applications for these specific

Above: Professor Artem Oganov


and his colleagues have managed
to turn salt into a variety of exotic
materials using high pressures
PROBING THE CORE OF THE EARTH
Studies of materials under enormous pressures is
helping us paint a picture of the centre of the planet

ONE OF THE biggest areas of them up and better understand what


high-pressure research is creating the Earth’s core is made of. “It helps us
conditions in the lab that exist at the understand the chemistry of the Earth,
Left: the two diamonds of a
very centre of planets. Researchers its various temperatures, the details of
diamond anvil cell are used to can put iron and its alloys under how it formed,” says Earth scientist
apply extreme pressure pressures of around 300GPa – similar Oliver Lord from Bristol University.
to that in the Earth’s inner core. They Andrew Jephcoat at the University
can then test the temperatures that of Oxford has also been using pressure
Oganov and colleagues found that when they the materials melt, their crystal to study the Earth’s core. He studies
put salt under a pressure of around 20 gigapascals structure and their density. These how helium can escape from molten
(GPa – the unit used to measure pressure), or about findings can then be compared with iron metal alloys and silicon compounds
200,000 times the pressure of the air, together the properties of the core, which we that were present in the formation of
with a little bit of additional sodium and chlorine, know about from the way seismic the Earth. Understanding that helium
it could form compounds such as NaCl3 and Na3Cl. waves pass through it. This enables can break up and escape from the
These compounds don’t have a neutral charge and scienists to tweak the compositions alloys tells us that the Earth’s core
PHOTO: STEVE JACOBSON, SCIENCE PHOTO LIBRARY X2

are thought to have net charges of –2 and +2, of the materials they’re could still hold plenty of the
respectively – forbidden under the standard rules studying to match helium isotope 3He.
of chemistry.
Although scientists are not exactly sure why Studying intense
these compounds form, only knowing that the pressures is revealing
how the Earth’s
reaction occurs over a couple of seconds, they core behaves
suggest that the laws of chemistry seem to change
under high pressures. “Our work shows the
existence of a whole new class of compounds,
previously overlooked by chemists,” says Oganov.
“There is clearly a lot that chemists still need to
learn about chemical bonding and rules determining
the stability of compounds, so we need more general
rules than the ones that exist today.”

JUNE 2014 / FOCUS / 51


M AT ER I A L S S CIENCE

compounds, given that they are only stable 5,500kg. Its weight will exert a force on the ground.
while under pressure, the work opens up If that force is spread over a large area (say the
the possibility of creating new compounds that elephant was lying down) then the pressure would
could exist at standard air pressure. “The reason be relatively small. But if the elephant managed to
we are so excited about this is that we found an stand on a single stiletto heel (with a square tip with
example of a very simple system that forms totally sides of 0.4mm) then the pressure would be huge.
unusual compounds,” he says. Other compounds Indeed, if you had around 650 elephants all stood on
the group have discovered so far include KCl3 each other’s backs on this one stiletto heel it would
and CsF2 – compounds containing potassium (K), be equal to the pressure inside the Earth’s core.
chlorine, caesium (Cs) and fluorine (F). In contrast While scientists don’t usually have access to
with NaCl3 and Na3Cl, they are stable at normal 650 elephants in the lab, they do have diamonds
air pressures. They could have applications in – one of the hardest materials known – to do all
The structure of the compound
storing toxic gases like fluorine and chlorine at low the squeezing. Scientists have been doing this NaCL3, which is formed by
temperatures, since when they are heated slightly since the late 1950s, following the invention of the applying pressure to salt with a
diamond anvil cell at diamond anvil cell

“There is clearly a lot that chemists still the US National Bureau


of Standards (now
need to learn about chemical bonding ” known as the National
Institute of Standards
Prof Artem Oganov from the State University of New York and Technology).
Diamond anvil cells
consist of opposing,
specially-cut diamonds
around a millimetre
they decompose to release the held gas. wide and weighing around 0.2 carats (40mg). The
What’s just as remarkable as the new chemicals tips of the diamonds are cut and are extremely
being created, is how simple it is to make them. smooth and finely aligned so that they encase the
The only thing needed to open the gates to this sample with identical and opposing force. Believe it
new chemical playground is a bit of pressure. or not, generating pressure is as simple as tightening
The extreme material NaCL3 has a
Well, a lot of it. bolts connected to the two sides of the cell with a single-atom thick layer of sodium,
common Allen wrench tool. The cells put a pressure which could prove to be an
of around 300GPa on a sample – similar to that excellent conductor of electricity
ELEPHANTS ON HEELS found in the core of the Earth.
Pressure is a measure of how much something is Crystals, like NaCl, are made up of an infinitely
stressed by applying a continuous physical force on repeating array of 3D ‘boxes’, known as unit cells.
an object by something in contact with it – pressure For example, salt’s unit cell is a basic cube shape,
being the force applied over the contact area. which contains the sodium and chlorine ions. What
Imagine an adult male elephant weighing around happens when pressure is applied to a material is

PUTTING PRESSURE UNDER THE MICROSCOPE The huge ESRF facility in Grenoble is
probing the behaviour of materials at
extreme pressures and temperatures
At a huge facility in France, materials under enormous pressure
can be blasted with X-rays so that we can examine their behaviour

ONE OF THE biggest facilities in the In May 2012, the ESRF opened a
world that can produce high-intensity new beamline with a speciality to
X-rays, enabling scientists to peer study – in real-time – the behaviour
PHOTO: DENIS MOREL/ESRF, ARTEM R OGANOV/ WEIWEI ZHANG

into the structure of a whole range of of materials at extreme pressures


di�erent materials, is the European and temperatures. Called ID24, the
Synchrotron Radiation Facility (ESRF) beamline cost €180m (£149m) to
in Grenoble, France. To do this, the build and lets researchers shine
ESRF accelerates electrons in a 270m X-rays into materials that have been
diameter storage ring and as the squeezed using diamond anvil cells.
subatomic particles travel in a circle The materials under study can also
they produce X-rays, which are sent be heated up to 10,000°C with short,
down 40 ‘beamlines’. Researchers intense laser pulses.
use these to carry out a range of With such intense pressure and
experiments in fields such as physics, temperatures, the experiment can
medicine and archaeology. Given how be used to test materials present in
powerful the ESRF is, the samples that the Earth’s liquid iron core – 2,900km
are used can be 10,000 times smaller beneath the surface – as well as what it
than those used in university labs. is like inside large planets like Jupiter.

52 / FOCUS / JUNE 2014


M AT ER I A L S S CIENCE

FEELING THE
SQUEEZE
How pressures in the
real world compare to
those created by the
diamond anvil cell.

that it squeezes the structure, slowly decreasing Another hotbed of research is in superconductivity
the distances between the atoms in the unit cell. – materials that allow for the flow of electrons
The advantage of using diamonds is that they are without any resistance, such as magnesium diobride
transparent, meaning that X-rays can then be used (MgB2). Most superconductors need to be cooled
to measure the structure of the material and how down to –200°C before the effect kicks in, but it
it changes under pressure without the diamond would be a boon for power distribution if a room-
affecting the signal from the sample (see ‘Putting temperature superconductor could be found. By
pressure under the microscope, p52). applying pressure to these compounds, it can either
Using diamond anvil cells, researchers can study increase the temperature at which they become
materials under pressure at different temperatures. superconducting or can even make a compound
Andrew Jephcoat, a physicist at the University of that isn’t superconducting at ambient pressure
Oxford, is using pressure to explore how hydrogen suddenly become so.
(chemical symbol H) forms unusual, weakly-bound Indeed, Oganov, together with Weiwei Zhang
compounds with other gases such as krypton at New York State, have used their crystal structure
(chemical symbol Kr) and xenon. This has led them prediction program – called USPEX – to calculate
to discover a new range of strange compounds such that a whole range of exotic materials should exist,
as Kr(H2)4. “These materials are of interest because even at normal ambient conditions. It will keep
they reveal the complexity of bonding possible and experimentalists busy for some years to come in
they help explain how hydrogen itself may behave attempting to create and make uses for them.
at extreme pressure,” says Jephcoat. He adds that “This is only the beginning,” Oganov declares. �
the work could be used to design new materials for
use in hydrogen storage. This is a key technology
for fuel cells that could be used in cars, for example,
since it converts the chemical energy from a fuel into MICHAEL BANKS is news editor of Physics World and has
electricity through a chemical reaction with oxygen. a PhD in condensed matter physics

JUNE 2014 / FOCUS / 53


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....Talk to the experts


THE MYSTERY
OF THE VOYNICH
MANUSCRIPT
The strange book has baffled experts
for a hundred years; no one has been
able to decipher its text… until now.
Brian Clegg investigates the riddle
The pages of the
Voynich manuscript
are littered with
strange drawings
of astronomical
diagrams, plants and
nymph-like characters
HE UNIVERSITY elegant manuscript. Some

T
of Bedfordshire claim it is a natural language,
announced in others a code and most
February 2014 recently that the whole thing is
that Stephen a hoax. Bax’s new translation
Bax, Professor brought the battle over the
of Applied Linguistics, had meaning of this remarkable
‘followed in the footsteps of book back to the fore.
Indiana Jones by cracking Around two years ago, Bax
the code of a 600-year-old heard about the book in a radio
manuscript, deemed the most programme on Elizabethan
mysterious document in the occultist John Dee, whose
world’. If true, a secret that association with the manuscript PHOTO: BEINECKE RARE BOOK AND MANUSCRIPT LIBRARY

had baffled experts for 100 was a long-standing assumption.


years was about to be revealed. Voynich believed that his find
The target of Professor Bax’s was the work of Roger Bacon,
work, the Voynich manuscript, the 13th Century friar, who
is a handwritten book the wrote copiously on science.
size of a paperback. Its 240 According to Voynich, the
parchment pages are filled book reached the hands of
with an intricate script and John Dee, who sold it to the
page after page of coloured Holy Roman Emperor, Rudolf
illustrations showing plants, II for 600 ducats (£200,000
patterns of stars and groupings in relative earnings.) The
of squat, naked nymphs. Since claim was based on a letter
its purchase in Italy in 1912 by dated 1665, found with
Polish-American book the manuscript.
collector Wilfred Voynich, the Bax was joining a long
book has been an enigma. No line of professionals and
one has been able to read the amateurs who had come up

JUNE 2014 / FOCUS / 57


CRY P TO GR A PH Y

TIMELINE 1404 1438 1586


The most likely date range Holy Roman Emperor
A history of the for the manufacture of the Rudolf II is said to
Voynich manuscript parchment of the Voynich, have purchased
from carbon dating. This does a book written by
not tell us when Roger Bacon for 600
1214 1292 the writing was
put on the
ducats. The dating
is largely from the
The lifetime of Roger Bacon, initially
thought to be the author of the
manuscript. This appears to be
parchment.
NIGELLA SAT
timing of a visit to
Europe by John Dee.

wishful thinking, and all the evidence


now points to a later date.

against this mysterious to break through the Using a technique similar a distinct shape, which isn’t
manuscript over the text. For a while, the to that used in decoding repeated in these stars. What’s
past 100 years – yet not one favoured hypothesis was Egyptian hieroglyphs, Bax more, although the Pleiades
of them has so far produced a that the manuscript was matched letters to the word are the ‘Seven Sisters’ of
convincing solution. Voynich a transliteration of a real kantairon, an approximation Greek mythology, there are
himself never got anywhere, language, which merely to a medieval version of the nine major stars in the cluster,
but he was presented needed a few keywords to plant’s name, encouraged by including two named after the
with an apparent partial crack it. Then there was the the appearance of an almost sisters’ parents. The Pleiades
translation nine years after the idea it could be a cipher, identical word, differing only cluster is in the constellation
manuscript was discovered, by a message that required in the final letter, on the page. of Taurus, but it is quite a
Another clue came from stretch to assume this link.
“The book could simply be a kind of zodiac, showing
a wheel with collections of
From his word matching,
Bax produced transliterations
gibberish. But why go to such stars between its spokes. Bax for 14 characters, over half
identified a group of seven the Voynich alphabet, and
e�ort to make a hoax?” stars with the Pleiades, hoping has since identified both
that an adjacent word referred the castor oil plant and the
to the constellation of Taurus. marshmallow plant. He has
This is a much weaker gambit, speculated that the language
PHOTO: SCIENCE & SOCIETY, ALAMY X2, SUPERSTOCK, BEINECKE RARE BOOK AND MANUSCRIPT LIBRARY

as the Pleiades cluster has may be an otherwise unwritten


Professor William Newbold of decrypting before it could
the University of Pennsylvania. be read. However, it quickly
Newbold briefly basked became clear that if this
in glory before his theory was the case it was a far
unravelled. He had decided more complex cipher than
that the script was a blind, any used in the Middle
and that the actual message Ages, which are trivial for
was carried in tiny markings a modern cryptographer to
above the symbols, which he decode. And finally there
claimed were similar to an was the idea that the book
Ancient Greek shorthand. could simply be gibberish.
But to come up with his But why go to such effort to
‘translation’ Newbold had to make a hoax?
take pairs of these characters Like many before him,
as single letters, then make Professor Bax picked out the
anagrams of words. With such initial words on the pages
complex manipulations of a showing plant illustrations.
manuscript it is easy enough Many of these are words
to read anything into it. used infrequently elsewhere
Newbold’s translation finally in the text, suggesting they
lost credibility when it was may correspond to the
shown that the markings were proper names of the plants.
cracking in the ink surface. One illustration resembles
Since Newbold there Centaurea, a thistle-like
have been many attempts genus of flowering plants.

58 / FOCUS / JUNE 2014


F LY ING S OLO

1666
Prague scientist Johannes Marcus
Marci writes a letter claiming that
a book with mysterious images
and text, possibly
by Roger Bacon,
was sold to
Rudolf II for

TIVA
600 ducats.

dialect from western Asia.


Other Voynich researchers
have pointed out there is an
oddity in his transliteration
as it makes a huge number of
the plant names start with C
or K. Similarly, plugging the
translation into the body text
of one page produced a script
where around half the words
end in R (partly because Bax
translates three Voynich letters
as R), and many more as N
– an unusual distribution for
any known language.
Soon after the university
went public, these apparent
breakthroughs received a
challenge from Dr
Gordon Rugg of Keele

Of all the plants in the


book Nigella sativa, or the
Fennel Flower, is one of
the most clearly depicted
in the Voynich manuscript
(illustration shown right)

A page from the Voynich


manuscript reveals the
intricate writing alongside
an illustration of a flower
thought to be Nigella sativa

JANUARY 2013 / FOCUS / XX


CRY P TO GR A PH Y

1912 1921 1978


Wilfrid Voynich, a New York-based William Newbold, Professor Mary D’Imperio publishes
antique book dealer, purchases of Intellectual and Moral The Voynich Manuscript:
the manuscript, which had been Philosophy at the University An Elegant Enigma, the
found at a villa near Frascati, Italy. of Pennsylvania, claims to first comprehensive
have found evidence that monograph on work
Bacon wrote the book on the manuscript.
in a partial translation of
mysterious markings above
the characters.

University. Rugg has Dee at the time of the alleged could also pass the statistical suggests that the Voynich
an interesting and visit to Rudolf II. test applied to the manuscript has meaning, but could also
arguably ideal background for Could Kelley produce by Marcelo Montemurro of the work with a fake using
analysing the Voynich. Initially such a complex manuscript? University of Manchester in Rugg’s approach.
trained in linguistics, he went While it has never given up its 2013, contradicting an Austrian In principle such a hoax
on to study experimental secrets, it does have a number statistical analysis from 2007 might have been undertaken at
psychology and now works of characteristics that suggest that declared it gibberish. The any point in history, although
in computer science. Rugg it isn’t pure gobbledegook. It Manchester technique maps the use of these grids in
had two problems with Bax’s has a complex, non-random ‘high information words’ and producing ciphers, making

“The book was sold for 600 Gordon Rugg is a firm believer
that the Voynich manuscript is

ducats, the equivalent of 8 to an elaborate hoax

10 years on an average wage”

announcement. One was structure. Yet if Kelley could


that this technique had been find a way of mocking up such
widely tried since the 1940s a script, he would have been
without success, and the other prepared to put in a good few
was that he believed that the months of work. If the book
manuscript was not a language was sold for 600 ducats, the
PHOTO: ALAMY X2, UNIVERSITY OF PENNSYLVANIA ARCHIVES, SIMON WESSON

at all, but a hoax. equivalent of 8 to 10 years on


By using technology from an average wage, making a fake
the time of John Dee, Rugg would have been worth it.
has shown that it would be To create such a document
relatively easy to produce a you would need a mechanism
fake Voynich manuscript. In for generating fake words.
fact Dee’s household becomes Using quill pens and parchment,
of particular interest here, Rugg demonstrated how easily
as Dee’s assistant, Edward this could be done, starting
Kelley, had already dreamed with a large table of word
up an artificial language with segments and combining
its own unique alphabet, them using a cut-out grid to
known as Enochian. Dee avoid sequential repetition.
used a number of ‘skryers’ or Using this technique and hand
mediums, including Kelley, drawing, Rugg reproduced
to communicate with spirits. an illustrated plant page in
It was Kelley who enabled around two hours, meaning
Dee to apparently use the the book might take 10 weeks
language of the angels, and to construct, a respectable
Kelley was involved with amount of time. This technique

60 / FOCUS / JUNE 2014


CRY P TOGR A PH Y

2012 2013 2014


Stephen Bax comes across Gordon Rugg publishes Blind Stephen Bax gives us the
the Voynich manuscript in a Spot, a book describing first few words in the latest
programme about John techniques to analyse errors attempt to uncover the secret
Dee (pictured) on in expert decisions, using the of the manuscript.
BBC Radio Four. Voynich and the possibility
that it is a hoax
as a major
case study.

them a natural technique for there was the combination


mocking up a fake language,
was only introduced in the
of the intriguing mystery
language and the alleged link FOR or AGAINST:
1550s. One obvious clue would to Roger Bacon, who was in
seem to be carbon dating, the news in 1912 as his 700th Is the Voynich manuscript fake?
and in 2010 a team from the anniversary approached, a link
University of Arizona declared that Voynich stressed. This Stephen Bax
that the parchment was most made it possible for the book
likely to have been produced dealer to value the manuscript Professor of Applied Linguistics at the University of Bedfordshire
between 1404 and 1438, much at $100,000. “The attraction for me personally was the oddity
earlier than the 1586 date of the script and the possibility that it might be
when the manuscript may have a script that I could decode. Many people have
been sold to Rudolf. ELABORATE HOAX? looked closely at the script and discounted that it
It doesn’t, however, rule out There’s more that adds weight might be a natural language. I’ve looked closely at
Kelley as the author. It wasn’t to the hoax theory. The it, taking full account of what they say, and I believe
uncommon for parchment manuscript features unusual as a linguist that it could well be a natural language.”
to be kept for decades before word repetition. One phrase,
writing on it, and it would be for instance, transliterated into Gordon Rugg
easy enough to take an old, familiar letters in a convention
part-used book, remove the used by Voynich researchers, Senior Lecturer in Computer Science at Keele University
pages that had been written on reads ‘qokedy qokedy dal “One key assumption that everybody made is
and make use of the rest. To qokedy qokedy’. Conversely, that complex structures need to have complex
cover this up, the manuscript it’s very unusual in the causes. There are complex structures within
might then be rebound out of manuscript to find frequently Voynichese, so everyone had thought that it
order so that the lost pages used phrases with two or three couldn’t be a hoax because those structures
weren’t all at the front of the words together, something that were so complex… But very simple causes can
book – and, interestingly, the occurs in most languages. produce very complex outcomes.”
Voynich manuscript does Then there is the absence
appear to have been bound of mistakes. In a notebook,
with the pages rearranged. with the lack of formality of Voynich pages, providing far a whole. Meanwhile, Gordon
If old parchment was used, the Voynich, you might expect more detail than is obvious Rugg’s hoax hypothesis is
it allows for an even more to see crossings out, and even to the naked eye – yet there intriguing, but could only
dramatic hoax suggestion the best medieval manuscripts was no evidence of a single ever be proved if supporting
– that Voynich himself was contain corrections. When correction. evidence from the period of
behind it. a scribe made an error, he It isn’t possible to give the forgery were discovered.
This has been suggested by would wait for the ink to dry, a definitive answer on the What remains is a delightful
Voynich researcher Richard then scrape it carefully off Voynich manuscript unless enigma, that will no doubt
SantaColoma. He believes the parchment before writing a solution provides a full prove as entertaining in the
that Voynich found the letter the new characters. However decoding. Stephen Bax’s next hundred years as it has in
giving the book’s provenance carefully done, this action translations are interesting, the first. �
and created a manuscript to leaves a mark on the surface but as yet he has not said
match. If it had been nothing of the material. A few years which language he believes the
more than an obscure herbal ago an examination was made manuscript is written in, nor BRIAN CLEGG is the author of
manual, it would not have of extremely high-resolution has he been able to apply his Dice World: Science And Life In A
been worth the effort, but here images of several of the transliterations to the text as Random Universe

JUNE 2014 / FOCUS / 61


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EMAIL YOUR QUESTIONS TO questions@sciencefocus.com


or post to Focus Q&A, Tower House, Fairfax Street, Bristol, BS1 3BN

MIKE ALDER, CARDIFF

What’s the largest floating object in the world?


IT’S SHELL’S PRELUDE Floating Goeje in South Korea. With the hull land. Instead, the FLNG will liquefy the
Liquefied Natural Gas vessel (pictured). complete, and weighing over 200,000 gas at sea.
It’s nearly half a kilometre in length with tonnes, it was moved to another part Strictly, the vessel is not a ship as it
a displacement in the water equivalent of the shipyard for its liquefaction does not travel under its own power but
to six aircraft carriers. It became the modules to be fitted. The FLNG is being instead will be towed into position.
largest hull ever to be floated in built to tap a natural gas reserve off the When completed it will weigh 600,000
November last year, after 14 months of coast of Western Australia. The reserve tonnes and produce gas equivalent to
construction at Samsung’s shipyard in is too remote for the gas to be piped to Hong Kong’s annual consumption. GM
“We’re not gonna
need a bigger boat”

PHOTO: SHELL

JUNE 2014 / FOCUS / 63


Q&A

In Numbers CRAIG WILCOX, THRAPSTON

3.253
seconds is the time that an ARM-processor-
powered robot made from Lego solved a Rubik’s
What percentage of the
Universe is visible from Earth?
Cube, beating the previous record of 5.27s.

SARAH O’BRIEN, SOUTHAMPTON

Why is the Arctic


warming faster than
the rest of the planet?
WHILE THE AVERAGE temperature
of the Earth has increased by around We can happily observe
0.8°C over recent decades, the Arctic is everything in the Universe up
to 46 billion light-years away
warming twice as fast. Recent research by
climatologists suggests this is because a
peculiar atmospheric layer over the THE UNIVERSE MAY be so big right at this limit of observability so it
Arctic traps in heat that would otherwise that the light emitted from its most would be correct to say we can see 100
escape. The disappearance of highly distant regions has not had enough time per cent of the ‘observable’ Universe.
reflective sea-ice also boosts the effect. RM to reach the Earth during its 13.8 billion However, the Universe is probably
year history. We will never be able much bigger than just the part we can
to see beyond this natural ‘horizon’, see. Unfortunately, at present we have
which is currently about 46 billion no way of deciding exactly how big the
light-years away. This ‘edge’ defines Universe is or even whether it is finite
what astronomers call the ‘observable or infinite. So, it’s not possible to say
Universe’. Our most powerful what percentage of the ‘entire’ Universe
telescopes can pick up signals that lie we can observe from Earth. AG

The Arctic is warming twice as fast as the rest of the planet

AUDREY SIMMS, CIRENCESTER

CHRIS TUTTLE, EDINBURGH


How do polar bears stay warm?
Is the Great Wall of
China really visible THEY ARE INCREDIBLY well
insulated with a layer of blubber that can

from space? be up to 10cm thick covered with another


15cm of fur. Polar bears lose so little heat
PHOTO: ALAMY X3, THINKSTOCK X2, GETTY, SCIENCE PHOTO LIBRARY

to their environment that they are almost


invisible to thermal imaging cameras. But
NO. EVEN FROM low Earth orbit the a recent study at the University of Buffalo
Great Wall of China is extremely hard to found that polar bears have also evolved
spot with the naked eye. It’s a very thin genes that produce more nitric oxide
line, almost the same colour as the than other bear species. Nitric oxide
landscape. Lots of other things are visible is a signalling molecule and one of
though, including cities, airports and the mechanisms it controls is whether
dams. From the Moon, no man-made cells use their available nutrients to
structure is visible. LV produce metabolic energy, or simply
convert it into body heat. Polar bears
seem to be able to divert more of their
body’s resources into generating heat.
The Great Wall This relies on them getting enough fuel
of China: big, but for this process and adult polar bears
not big enough to
see from space have a high calorie diet; they mostly eat
seal blubber. LV The polar bear is a master of heat management

64 / FOCUS / JUNE 2014


Q&A
WINNE
RichardR! wins a c
of Illusio opy It’s a smelly job,
n Confu
The Won sion - but someone’s
derful W got to do it
Optical orld Of
Decepti
(Thame o n
s&
QUESTION OF THE MONTH Hudson
, £18.95
)

PAUL MELLOR, ST ALBANS

Why do we get
used to smells?
OUR NERVOUS SYSTEM has
evolved to become progressively less
sensitive to a stimulus, the longer it
persists. This enables us to concentrate
on the newest sensations that are more
likely to be an opportunity or a threat.
We also have an olfactory memory that
discards smells that we have experienced
recently. This means that you don’t notice
the smell of your house when you come
home from work, but it smells strange
when you come back from holiday. LV

A ‘nail knot’ used


by fishermen BOB BROWN, USA

RICHARD O’NEILL, GLASGOW


What keeps
How many different types electrons moving?
of knot are there? ELECTRONS ARE OFTEN portrayed
whizzing round the nuclei of atoms like
PEOPLE HAVE BEEN knots. This has revealed the planets orbiting stars. Theory shows,
inventing knots for millennia; existence of truly fundamental however, that if electrons really did
the oldest known – used in a ones that can’t be unravelled behave like this, they’d rapidly lose
fishing net found in Finland into collections of simpler ones. energy and crash into the nuclei. The
in 1913 – dates from around Taking prime numbers as reality is much more abstract, with
8000BC. Thousands are now an analogy – which can’t be electrons being more like fuzzy clouds
known, but they’re not all divided by anything other than surrounding the nuclei. RM
unique: some are just themselves and one – these
combinations of others. are so-called prime knots. The
Actually deciding whether simplest is the so-called trefoil
two apparently different tangles knot; a combination of two of
of string are really just the these form the famous ‘granny
same knot in disguise or some knot’. There’s an infinite number
combination is far from simple. of prime knots, and these form
So to bring some order to the an infinite number of composite
chaos, mathematicians have knots. I wouldn’t go trying to
developed ways of classifying untangle them all! RM

The traditional view of an electron whizzing round a nuclei


may not be accurate; they’d lose too much energy

JUNE 2014 / FOCUS / 65


Q&A

RACHEL LAWSON, LEICESTER

TOP TEN Does taking pictures help us remember things?


DEADLIEST SNAKES
Based on the LD50 (lethal dose 50%) test - the
amount of venom required to kill half a test pool SOMETIMES, BUT IT can also do less detail of the photographed items.
of mice, expressed in mg/kg the opposite. Photography can spoil our However, the effect was fragile. If they
memories if we rely on having pictures zoomed in on specified areas of the
to take home instead of enjoying life objects, they recalled more details not
as it happens. Tourists who hold their fewer, even recalling details that were not
1. Hook-nosed phones or cameras up all day cannot look in the photos.
seasnake properly at the sights, let alone engage Indeed photographs can help memory
LD50 (mg/kg): 0.02 deeply with people and emotions. A in other ways. Concentrating while
Length: up to 1.5m specific ‘photo-taking-impairment effect’ choosing a shot requires attention which
Location: South Asia waters
was recently discovered when in turn aids memory. And looking
students photographed 15 objects at photos later helps us remember
2. Russell’s viper in a museum and just looked at more about the context and the
LD50 (mg/kg): 0.03 15 others. They remembered events we chose to record. SB
Length: up to 1.7m
Location: Asia
Just what is she smiling
at? Perhaps the desire of
millions to take a photo
2. Inland taipan
LD50 (mg/kg): 0.03
Length: up to 2.5m
Location: Australia
THINKSTOCK X2, PETER WOODARD/ WIKIPEDIA, ALOAIZA/ WIKIPEDIA, NIGEL MARSH/SEAPICS.COM, ALAMY X5, SUPERSTOCK, SCIENCE

4. Dubois’s reef
seasnake
LD50 (mg/kg): 0.04
Length: up to 1.5m
Location: Australian waters

5. Eastern brownsnake
LD50 (mg/kg): 0.05
Length: up to 2.4m
Location: Australia, Papua
New Guinea, Indonesia
ALEXANDER STIRLING, LOSSIEMOUTH
5. Black mamba
LD50 (mg/kg): 0.05
Length: up to 4.5m
Location: Sub-Saharan
If you could store food in a perfect vacuum,
Africa
how long would it remain edible?
7. Tiger rattlesnake
LD50 (mg/kg): 0.06 FOOD SPOILS BECAUSE of it also changes the taste and texture of
Length: up to 0.9m
Location: Southwestern chemical changes and the growth of the food. To preserve flavour, the dried
USA bacteria. There are plenty of bacteria strawberries in some breakfast cereals
that don’t need oxygen to survive are preserved by freezing them and then
8. Boomslang and some of the most dangerous drying them in a vacuum. LV
LD50 (mg/kg): 0.07 ones actually require an oxygen-free
Length: up to 2.0m environment to grow. Vacuum-packing
Location: Sub-Saharan food can actually activate the spores of
Africa
Clostridium botulinum, which causes
botulism, for example. So a vacuum
8. Yellow-bellied
seasnake doesn’t protect food by itself. Food that is
LD50 (mg/kg): 0.07
vacuum sealed is first cooked to kill any
Length: up to 1.1m existing bacteria and then packaged to
Location: Pacific, Indian Oceans prevent new bacteria getting in. Vacuum
packing is about as effective as canning
10. Common Indian in this regard and some foods can last
krait several years.
LD50 (mg/kg): 0.09 If you just expose food unprotected to
Length: up to 2.1m
Location: India a vacuum, it will rapidly lose moisture. Clostridium botulinum wakes up when it finds itself in a
This prevents bacteria from growing, but vacuum and can then make you very ill indeed
PHOTO:

66 / FOCUS JUNE 2014


Q&A

HOW IT WORKS

NASA STARSHADE
Tightly wrapped up for the journey to
space, the starshade is launched as a
package with a space telescope.

WE KNOW ALIEN worlds are there - we’ve


detected over 1,800 of them. But as yet just a
handful of images have been taken of only the
largest, giant Jupiter-type worlds as specks of
light. The quest is on to take a snap of a small,
rocky planet close to its parent star – a world
like ours. We could then analyse its spectra to
see if it could be teeming with life.
The problem is that stars are so bright that
The starshade is released from the
it’s near impossible to see anything orbiting telescope and begins to unfurl its
them. But NASA has a surprisingly beautiful petals to reveal its flower-like form.
solution - a huge flower-like starshade that
can be perfectly positioned in space to block
the light from the star. A telescope can then
image its surrounding worlds. While it’s just a
concept, NASA says it could be launched with
a telescope in the future.

Fully deployed, thrusters on the


starshade itself manoeuvre it
into position. It requires millimetre
accuracy to e�ectively block
the starlight for the waiting
space telescope.

The flower-like shape of the


starshade doesn’t just look pretty.
The jagged edge formed by the petals
means that light rays from the star
are bent less, making the shadow of
the starshade very dark and reducing
glare. The telescope is then able to
snap the orbiting planets.

JUNE 2014 / FOCUS / 67


Q&A

EDDIE RACOUBIAN, BY EMAIL


CLAIRE MYLOR, ANDOVER

What would happen if an Why does tea taste


asteroid hit our Moon? better with freshly-
MOST ASTEROIDS ARE small and
slow enough to simply hit the Moon and
boiled water?
create a new crater. Even the largest
asteroid, Ceres, at 975km (605 miles) in
diameter, probably wouldn’t cause much
lasting damage, although it would be a
spectacular explosion viewed from Earth!
It would take an object similar in size to
the Moon to break the Moon up or send it
hurtling into the Earth. AG

To re-boil or not to re-boil,


that is the question

The Moon is marked with


craters from countless impacts PACKETS OF TEA often say ‘boil limescale in the kettle might affect the
freshly drawn water’ and a famous taste after repeated boiling. But could
brand gives ‘Monkey’s top tips’: ‘Use the oxygen theory be true? No. If you
fresh tap water: it contains more oxygen, heat a pan of water you can see the first
KATIE SCOTT, CANTERBURY
which makes for a fuller flavour.’ What’s bubbles coming off long before the

Why can we see clearer more, tea expert Simon Hill, a buyer
from Taylors of Harrogate claims that
if water is boiled twice “the taste is
water boils. These are dissolved gases
coming out of solution. This means that
most of the oxygen has gone long before
when we squint? flatter and the colour is duller and less
reflective”. You might assume that
boiling point, leaving deaerated water.
So re-boiling should make no difference
experiments have been done to reach – the oxygen has already gone. Yet
SQUINTING USES THE muscles of this conclusion, such as blind tastings because of this myth some people throw
the cheeks and eyebrows to close up the comparing cups of tea made with water away water left in the kettle and start
eye. This blocks out some of the light, so boiled 10 times or just once. But no again. Some even think that if they boil a
the image is darker, but what is left is the such experiments have been published. kettle and then leave it for a few minutes,
light coming in at the shallowest angles. But maybe freshly boiled water does they must throw the hot water away and
Your eye doesn’t need to bend make a difference. For example, dirt or start again. What a waste of energy! SB
these rays as much to bring
them to a point on your
retina, so the image is in
MARION GROVES, DORSET
focus. You can exploit
this effect to make a
pair of reading glasses What happens to worms when the ground floods?
PHOTO: SCIENCE PHOTO LIBRARY, ALAMY X2, PRESS ASSOCIATION

by putting pin holes in


a piece of cardboard
and looking through EARTHWORMS DON’T HAVE
that. LV lungs or gills; they absorb oxygen directly
through their moist skin. Earthworms
Hopefully you aren’t having to squint to read this don’t drown and can survive for several
weeks in water if it is kept oxygenated.
In flooded soil though, oxygen diffuses
more slowly and plant roots absorb what
In Numbers
little there is, so the oxygen in the worm’s

1,300
times the diameter of the Sun, is the size of
burrow can become rapidly depleted.
Some species have low enough metabolic
rates that they can tolerate this, but
the largest yellow star ever discovered. The the common garden worm Lumbricus
‘hypergiant’ star is called HR 5171 A. terrestris will surface after heavy rain When you see earthworms on your lawn on a rainy day,
to get some air, until the soil drains. LV have a little sympathy - they’re gasping for air

68 / FOCUS JUNE 2014


Q&A

CAREL LUCAS, PERTH, AUSTRALIA

What causes addiction?


ADDICTIVE DRUGS INTERFERE opioids that induce pleasure and reduce
with neurotransmitters, the chemicals pain. The brain responds by reducing
that transmit signals around the brain, the number and sensitivity of its opioid
and their receptors. This causes changes receptors so that more of the drug is
to the brain’s reward system. This can needed. Nicotine increases dopamine
create craving and tolerance, so that and activates the brain’s rewards
a higher dose is needed to have the pathways. Again, the brain compensates
same effect. Some also have unpleasant so that more nicotine is required.
withdrawal symptoms that are only People can also become addicted
relieved by taking more. Heroin is the to activities such as sex, gambling or
most addictive drug known. It mimics shopping, but the mechanisms underlying Heroin, seen here under a micrograph, alters the brain’s reward
the brain’s own endorphins, the natural these addictions are less well understood. SB system leading to addiction

BEN FERRIS, LONDON

At what altitude can you see the curvature of the Earth?


FROM FELIX BAUMGARTNER’S Passengers on Concorde were able to of California-based optics consultancy
world record skydive to teddy bears see the curvature of the Earth, implying Thule Scientific carried out a detailed
carried aloft in balloons, we’re all that an altitude of 60,000ft (18.3km) is analysis, published in the journal Applied
familiar with photos taken from ‘the more than enough. Pilots and cabin staff Optics in 2008. He concluded it’s just
edge of space’, with the curvature of the flying considerably lower have sometimes possible to see the curve of the Earth at
Earth in clear view. It’s all a bit of an claimed to have seen the curvature too, around 35,000ft (10.7km) – given perfect
exaggeration, though: even Baumgartner’s but there’s long been a suspicion that conditions. This suggests that the
39km (24-mile) high jump was well they were being fooled by optical curvature of the Earth can be seen from
below the 100km (62-mile) height distortion by windows. To get to the heights barely 10 per cent of the height of
usually taken to be where space begins. bottom of the mystery, Dr David Lynch the threshold of space. RM

Felix Baumgartner could


see the curvature of
the Earth, but he wasn’t
technically in space

JUNE 2014 / FOCUS / 69


Q&A

LEN DAWES, ASHFORD TASHA LEWIS, MANCHESTER

How do you fix a sinkhole? Are all dogs descended from wolves?
SINKHOLES FORM in an impermeable plug that YES. BEFORE THE advent rearing the orphaned pups of
chalk or limestone areas diverts subsurface water of DNA sequencing, it was adult wolves that had been
where the bedrock is eroded around it and can actually thought that dogs might have hunted. Selective breeding
by underground streams, accelerate erosion. For larger jackal and coyote ancestors slowly favoured the traits
leaving a thin roof that holes, it is better to fill most of as well as wolves, but this most useful to humans. Some
eventually collapses. You can the void with large rocks and has now been disproved. The modern breeds, such as the
repair small ones by excavating boulders that leave gaps for grey wolf (Canis lupus) was Alsatian, may be the result
down to stable bedrock and drainage, layering smaller first domesticated some time of later cross-breeding with
then filling in the hole with grades of rocks, gravel and between 15,000 and 33,000 wolves to reintroduce some
concrete. But concrete creates finally sand. LV years ago, probably by hand wild characteristics. LV

You’ll need a lot of The Chihuahua’s


concrete to fill up distant ancestor -
a sink hole the grey wolf

SUSIE LANE, POOLE


RILEY BRIGHTWELL, CAWSAND

Will we have more How do we know what the


electricity blackouts Milky Way Galaxy looks like?
in the future?
A JOINT STUDY published earlier
this year by the University of Lincoln and
the University of Auckland concludes
PHOTO: CORBIS, THINKSTOCK X3, ALAMY, SCIENCE PHOTO LIBRARY, THE NATIONAL GRID

that we will. The study analysed energy


supply and consumption across the
major Western countries. From here
it projected an 80 per cent growth in
demand worldwide by 2035, requiring an
additional 5,900 gigawatts of power. If
we continue to build power stations at the
You can see the plane of stars that
present rate, supply will fall short and the make up our Galaxy by looking up
lights will go off more often. GM at the Milky Way on a clear night

IT IS, OF course, difficult to comes from studies of gas clouds. By


deduce the appearance of something measuring the velocities and positions
when you are embedded within it! But of these clouds, astronomers are able to
astronomers can map the distribution of show that they are distributed in a loose
the stars and their motions quite easily. spiral pattern around the galactic centre.
This shows us that the stars of the Milky However, astronomers are unsure how
Way are orbiting a central ‘bulge’ (in many spiral arms there are.
the constellation Sagittarius) and are So, although we can’t see the Milky
distributed in a thin plane. Way from the outside, the evidence
The most convincing evidence for suggests it has a structure much like the
This chap at the UK’s Electricity National Control Centre is
the spiral structure of the Milky Way other spiral galaxies we see around us. AG
going to have a tough job come 2035

70 / FOCUS JUNE 2014


Q&A

SOPHIE DUNLOP, EWHURST

How long could humans survive if all


green vegetation disappeared?

Without plants the


world’s land ecosystem
would collapse

IF GREEN PLANTS literally Long before that almost every land ecosystems depend on the photosynthesis
vanished, there would be massive floods ecosystem would have collapsed as the of unicellular algae, rather than green
and landslides as the soil lost the herbivores, and then the carnivores, plants. We might even be able to cultivate
stabilising effect of plant roots, and starved to death. Humans probably the algae ourselves. Marine algae also
rainwater ran straight off the surface. If wouldn’t die out completely though. produce about 50 per cent of Earth’s
they were all killed by a mysterious Existing food stocks would last about a oxygen, so there would still be plenty to
virus, there would be enormous wildfires year in developed countries and we breathe – particularly since we would be
as dead forests became tinder-dry. could still get food from the sea. Marine virtually the only land animal left. LV

KATHRYN FRIEL, CAMBRIDGE


WHAT IS THIS?
What fills the spaces left by oil extraction?
Extracting oil is
like sucking it
from a sponge

OILFIELDS AREN’T VAST into the gaps. As the oilfield is depleted,


underground caves filled with oil that more and more water comes out along
form empty voids as the oil is pumped with the oil, until it’s uneconomical to
out. Rather, the oil seeps through extract any more. LV
layers of porous sandstone or limestone
rock, and collects in places where an
KNOW THE ANSWER?
` Go to sciencefocus.com/qanda/what
impermeable rock layer prevents it from
rising to the surface. Extracting oil is NEXT MONTH Over 20 more
and submit your answer now!
LAST MONTH’S ANSWER:
more like sucking from a sponge than
drinking through a straw. When the
of your questions answered
Jens Jensen correctly guessed a
oil is removed, the pressure from the For even more answers to the most puzzling
gas drilling platform
surrounding rock forces groundwater
` questions, see the Q&A archive at
www.sciencefocus.com/qanda

JUNE 2014 / FOCUS / 71


EN V IRONMEN T

G
REY SQUIRRELS LOOK cute, don’t they?

ALIEN INVADERS
Originally from North America, the
critters have nearly driven the smaller
red squirrel out of the British Isles. In
fact, they’ve become so established that
the Government recently scrapped a law
requiring people to report sightings. All
over the world, invasive species are
causing similar trouble. Hundreds of thousands of
organisms have been transported around the
world by humans, making us the most destructive
species of all. The majority fail to escape into the
wild, but some go on to establish populations.
Some wildlife isn’t where it ought to be, with While a lot of these species don’t cause much
trouble, the few that do are generally referred to
disastrous consequences. Dr Ken Thompson as ‘invasive’, and can wipe out native creatures.
Here are some of the most destructive ‘aliens’
identifies some of the most destructive species that are wreaking havoc around the globe.

BROWN TREE SNAKE


The brown tree snake has
a taste for Guam’s bird life

NATIVE TO AUSTRALIA causing power cuts. But snake from repeating


and New Guinea, the the main economic cost its original stowaway
brown tree snake arrived of the snake falls on trick. It could hitch a ride
on the Pacific island of Guam’s two main sources to other islands, such
Guam as a stowaway of income: tourism and as Hawaii, where it is
in military cargo in the the military. The presence estimated it could cost
late 1940s. As the snake of a large venomous $1.7 billion a year in
ALAMY, FLPA, SUPERSTOCK

spread, it wiped out snake doesn’t exactly power cuts alone, plus
the island’s birds. Ten encourage visitors, and all the other environmental
forest birds are now clearly birdwatchers damage. An attempt
extinct and the remaining needn’t bother visiting. to control them with
species are very rare. The island is also the site poisoned mice is
The snakes also of a US military base and underway, but it’s too
frequently short-out the sta� have their early to know if it will
power lines, hands full preventing the be successful.
PHOTO: MILES BARTON/NATUREPL.COM, DYLAN PARKER/ WIKIPEDIA

THE ROSY WOLFSNAIL


It may not look fierce, but the
rosy wolfsnail is a nemesis to
other island snails

PUT ON ISLANDS where be much worse than Everywhere Euglandina


they shouldn’t be, the disease. has been introduced,
predators often cause The problem is that most of the native snails
mayhem, especially if Euglandina isn’t very are now extinct.
nothing there wants to keen on eating the giant Experience shows
eat them. Florida’s African snail, but it’s an that, given enough money
Euglandina, or the rosy extremely e�ective and commitment,
wolfsnail, is such a beast. predator of smaller eradicating introduced
It was released on many snails. To make matters predators from islands is
Pacific islands to control worse, the Pacific islands possible. But Euglandina
the giant African snail, support (or used to is just too abundant, on
which was itself support) a staggering far too many islands, for
introduced, and became diversity of snails: 931 there to be any realistic
a problem. But the species in the Hawaiian prospect of eradicating
cure turned out to archipelago alone. this devastating species.

72 / FOCUS / JUNE 2014


EN V IRONMEN T

CANE TOAD
HAVING TACKLED THE beetles in Australia, but cane toad look bleak, but
prickly pear cactus with did eat nearly everything in the longer term, natural
an Argentinean moth, else they came across. selection should come to
Australia was in the This is bad enough, but our aid. Native Australian
mood to try other control they soon caused other predators, from birds to
organisms in 1935. The problems. The toads ants, are figuring out how
South American cane secrete toxins that are to eat cane toads, while
toad looked like a good deadly to predators, and native reptiles are
bet. It had (apparently) in Australia they have evolving to avoid eating
been successful at been responsible for them and also resistance
controlling cane beetles declines in native reptiles, to the toxin. One snake
in Hawaii, a major pest of which are killed when has even evolved a
sugar cane. Unfortunately, they try to eat the pest. smaller head, making it
Native Australian reptiles like the
taste of cane toads – the problem is
cane toads had no The prospects for less likely to attempt to
the toxic amphibians can kill them e�ect on cane ridding Australia of the munch on larger toads.

The water hyacinth’s beautiful


flowers have meant that, with human
help, it’s conquered the world WATER HYACINTH
ORIGINALLY FROM grows rapidly and forms moths and two weevils
South America, but dense mats. These clog have been introduced
now worldwide, water irrigation channels and to tackle it and have
hyacinth was widely intakes for hydroelectric certainly had an e�ect,
introduced as an plants and power station but haven’t won the war.
ornamental plant and is cooling water. It also puts Interestingly, water
indeed very attractive, native submerged plant hyacinth’s dried, woven
with large, purplish-blue species in the shade and leaves, which are tough
flowers. But it is reduces dissolved oxygen yet flexible, now form
notoriously di�cult to levels, harming fish. the basis of a thriving
prevent aquatic plants Mechanical control is furniture industry. One
from escaping into the expensive and herbicides factory in Thailand
wild and spreading undesirable, so the plant employs over 1,000 local
through river systems. has been a target for villagers to harvest the
Water hyacinth biological control. Two plant from waterways.

DROMEDARY
THE FIRST FOUR aliens There are now about job, if only Australians
here are all on the 1 million, accused of would stop persecuting
Global Invasive Species causing soil erosion and the wild dog for its habit
Database of the world’s damaging livestock of eating sheep. The final
100 worst invasive watering stations. The irony is that dingoes do
species. Camels aren’t, problem is that without a help to control both foxes
but there are many predator, the population and cats, which are on
Australians who think is out of control. Ironically, the list of the world’s 100
they should be. Large the dingo could do the worst invasive species. �
numbers of them were
The Dromedary has
taken to the Australian imported Down Under
wilderness… 1 million in the 19th Century,
of them and then released DR KEN THOMPSON is the author of
Where Do Camels Belong? The Story
when motorised
And Science Of Invasive Species
transport arrived.

JUNE 2014 / FOCUS / 73


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WHY WE LOVE ALCOHOL

ILLUSTRATOR: MAGICTORCH

We all like a drink sometimes, but so do apes, flies and


many other animals. Biologist Robert Dudley asks
whether our thirst for booze can be put down to evolution
JUNE 2014 / FOCUS / 75
E VOL U T ION

W
ALK INTO ANY pub or
restaurant, and you will find
people enjoying alcoholic
beverages. Or perhaps not
enjoying them, if they have had
too much and then proceed to
stagger into the street and rudely vomit.
What is it about the alcohol molecule
PHOTO: FIONA ROGERS/NATUREPL.COM, ALAMY, THINKSTOCK, ALEX HYDE/NATUREPL.COM, SOLVIN ZANKL/NATUREPL.COM, ANNETTE ZITZMANN, OTTO PLANTEMA/FLPA, PHOTO RESEARCHERS/FLPA

that can either inspire us via cuisine and


social culture, or alternatively destroy us
through liver cirrhosis and drink driving?
A new evolutionary perspective, termed
the ‘drunken monkey hypothesis’, links
the psychoactive effects of alcohol to
our ancestral exposure to the molecule
as fruit-eating primates. Fruit contains
sugars that form the basis of the diet
for thousands of species of birds and
mammals. And particularly in the moist
tropics, where air temperatures are high
and yeasts abound, these fruits partially
ferment and contain alcohol in addition
to their carbohydrate rewards. Animals
consuming them enjoy a tipple as well.
This isn’t necessarily a bad thing. Over An object approaches a black
long distances, the smell of alcohol vapour hole’s event horizon in this
reliably points to the presence of calories artist’s impression, but is this
really the point of no return?
for animals to find the fruit. And once
there, alcohol can stimulate the appetite,

“Today, we are Fruit flies love a tipple - they use


alcohol vapour to detect ripe fruit;
clearly demand- and they’re helping us understand the
mechanisms behind addiction
not supply-limited
in our consumption
of alcohol”

promoting faster rates of consumption.


This is well known to us today as the
apéritif effect. Our behavioural responses
to alcohol may therefore have been moulded
over evolutionary timescales. Although
usually beneficial, some aspects of our
relationship with alcohol can also drift
into patterns of excessive consumption
and abuse. This too may be an unfortunate
but predictable product of evolution.

A POISON THAT HEALS?


Many compounds that we eat are essential
for living, but are also unhealthy or even
toxic at sufficiently high levels. Obvious
examples include fats and carbohydrates,

76 / FOCUS / JUNE 2014


E VOL U T ION

ALCOHOL-LOVING ANIMALS
fruit upon which they lay their eggs, PEN-TAILED
Primates like this western
and within which the larvae develop. TREESHREWS
lowland gorilla developed
stereoscopic, colour vision and Exposure to booze is therefore a natural These close relatives of
a keen sense of smell to detect feature of their biology. But what exactly the primates lap up
fermenting fruit in the jungle is the historical background for alcohol fermenting nectar all night
consumption in primates, and more long from blossoms of the
importantly, in the lineage leading to large bertram palm. The
modern humans? Malaysian animals never seem to get drunk, but
hair samples reveal the presence of a secondary
product of alcohol (ethyl glucuronide), which
DRUNK MONKEYS otherwise turns up only in human alcoholics.
Humans eat from a wide range of food
items, but until recently we were much
less catholic in our diet. As great apes, FRUIT-FEEDING
we are derived from a predominantly BUTTERFLIES
fruit-eating lineage of primates. For Particularly in the tropics,
example, our closest living relatives many butterflies visit fallen
(the gibbons, orangutans, gorillas, and and fermenting fruits
chimps), are all strongly dependent rather than flowers to
on large, sugar-rich fruits. The only obtain nourishment.
exception are the highland gorillas (as Reports of inebriated butterflies, and the use
popularised by Dian Fossey and her of gloopy mixtures of molasses and beer to
book Gorillas In the Mist), which eat attract moths in the temperate zone, suggest
herbaceous vegetation given the absence the important behavioural roles of alcohol.
of large fruits at elevations in the tropics
exceeding 1,500m. Primates actually
diversified in the lowland tropics as CEDAR WAXWINGS
fruit eaters about 45 million years ago. The Cedar Waxwing and
Various sensory adaptations, including other fruit-eating birds in
stereoscopic (3D) and trichromatic the temperate zone
(colour) vision, enable primates to see occasionally turn up drunk
basic fuels of life that nonetheless can ripe and colourful fruit, which can on the ground and unable
result in obesity when eaten in excess. otherwise be hard to find at distance in to fly. One report of mass
Similarly, many vitamins and minerals the green and cluttered forest canopy. mortality in Cedar Waxwings revealed
are necessary components of the diet, but Olfactory (smell) sensitivity of dangerously high levels of alcohol in the liver,
only in very small quantities; excessive monkeys to various kinds of alcohol has consistent with lethal inebriation.
consumption can be dangerous. This effect also been shown to be high. “Spider
has been termed hormesis by toxicologists, monkeys are a perfect species with
whereby moderate levels will maximise which to test the drunken monkey FRUIT FLIES
benefits and minimise costs of exposure hypothesis,” writes anthropologist Female fruit flies fly
to otherwise potentially toxic compounds. Dr Christina Campbell at California upwind when smelling
Abstention can be equally unhealthy. Can State University, Northridge. “They are alcohol vapour and look
alcohol consumption be viewed similarly? highly frugivorous [fruit-eating] and for fermenting fruit upon
The scientists would say yes. Starting in have been shown to be extremely which to lay their eggs.
the 1970s with the work of Art Klatsky at sensitive in their ability to discern low The larvae are equipped to
Kaiser Permanente in Oakland, California, levels of ethanol in taste experiments.” be able to metabolise di�erent concentrations
numerous studies since have demonstrated Her work in Panama assesses of alcohol. What’s more, male fruit flies rejected
substantial benefits to human health and alcohol levels in wild fruits preferred by females prefer alcohol-enhanced food.
overall life-span from moderate levels of by monkeys, and relates them to the
alcohol (one to three typical drinks a day), secondary products of alcohol found
relative to either abstention or higher in both urine and hair samples. And it
levels of drink. Most, but not all, of these may not just be fruit that’s supplying VERVET MONKEYS
effects come from reduced cardiovascular primates and other animals with booze. On the Caribbean island of
risk. And remarkably, similar outcomes can Biologist Frank Wiens spent years in the St Kitts the African monkeys
be found with adult fruit flies exposed Malaysian rainforest studying the steal tourist drinks on the
to alcohol vapours at different reactions of slow lorises, tree beach and wreak mayhem
concentrations. Their life-span is shrews, and other mammals to among the sunbathing
highest at intermediate levels the nectar within flowers of a public. In controlled
of exposure. Fruit flies in large palm tree. The nectar was experiments with captive populations, some
nature follow alcohol found to be consistently individuals avoid alcohol whereas others binge
plumes upwind to find fermenting and providing drink, leading to premature death. Most
ripe and fermenting alcohol rewards. Many monkeys tend, however, to drink moderately.
Spider monkeys have a
particularly fine taste
for alcohol JUNE 2014 / FOCUS / 77
E VOL U T ION

Hummingbirds feed on nectar,


which ferments to alcohol

species of birds, like hummingbirds


and sunbirds, and of course
“We enjoy a deeply
numerous insects, also feed on nectar
full-time. So it’s important to understand
rooted fruit-eating
that a natural exposure to alcohol may dietary heritage,
be much more widespread than we
currently realise. given our ancestors
Over the last two million years, humans
have diversified their diets, and with the
were aping about
origins of agriculture we have deviated in the forest”
dramatically from earlier sources of
food. Nonetheless, we enjoy a deeply
rooted fruit-eating dietary heritage,
given our ancestors were aping about
in the forest. And whoever was eating once worked safely in the jungle, where
ripe fruit was also consuming alcohol, fruits contain only small amounts of
albeit in small amounts. In parallel with alcohol, can be dangerous when we
the first Neolithic experiments in plant forage in the supermarket for booze.
cultivation, the intentional fermentation Today, we are clearly demand- and
of fruits and grains may also have provided not supply-limited in our consumption
psychoactive impetus to master the skill of alcohol. And for the unfortunate few,
of farming. The invention of distillation, this lust for drink can lead to alcoholism.
a chemical process dating back only But recognition of our ancestral dietary
several thousand years, then provided the exposure to the molecule suggests that
possibility to consume high-concentration our current responses may be based on
alcohol in pure liquid form. Unfortunately, behaviours that were once advantageous.
behaviours and nutritional strategies that The rapid identification and consumption

UNRAVELLING ADDICTION
Drunk fruit flies are shedding light on the cellular mechanisms behind alcoholism

ADDICTION TO ALCOHOL poses Flies placed within an alcohol Dopamine plays a crucial role
major health challenges, but plume will fly upwards toward in the cause of addiction
it’s obviously not possible to a light, becoming progressively
experiment with humans to more drunk and then settling out
understand the cellular changes on a series of stacked funnels.
underlying the disease. However, The higher fliers are thus more
fruit flies present a useful model resistant to alcohol and can be
with which to study various collected for genetic analysis.
physiological mechanisms that The wonderfully named
come into play during addiction. ‘happy hour mutant’,
Alcohol influences many for example, handles
di�erent features of the nervous booze fairly well,
system in all animals. However, a whereas ‘cheap date’
number of cell signalling pathways is particularly prone
to inebriation. The
PHOTO: GETTY X3, SCIENCE PHOTO LIBRARY

within the neurones of fruit flies


and rodents are activated similarly ‘hangover mutation’
during alcohol exposure. Many provides for greater
addictions involve changes to the short-term tolerance.
neurotransmitter dopamine, which We don’t yet know if comparable
acts in motivational and reward genetic variants influence human
neural circuitry. In fruit flies, a responses to alcohol, but the use
number of genetic mutants have of fruit flies as a model permits
been identified that influence both the full line-up of modern genetic
susceptibility to alcohol and the tools to be applied towards
ability to degrade it once exposed. understanding addictive behaviour.

78 / FOCUS / JUNE 2014


E VOL U T ION

of alcohol-containing fruits, so useful


in the rainforest, can become a problem
in the modern world. Similar arguments
have been given as a cause of diseases
like obesity and diabetes, with the
essentially unlimited availability of
cheap sugars and fats. These so-called
diseases of nutritional excess derive from
a mismatch between ancient and modern
food environments. Could alcoholism
have similar origins?

DRINK AND HUMANS


An intriguing hint to this effect is
provided by genetic differences among
modern humans in the ability to
metabolise alcohol, and correspondingly
in the tendency to drink. In East Asia,
many individuals possess a slow-acting
version of the enzyme (ALDH) that
serves in alcohol metabolism. If they do
drink, toxic intermediate products build
Fermentation takes place at a up and make them sick, so they tend
whisky distillery; the process
enabled our ancestors to drink higher
not to drink at all. We don’t yet know
concentrations of alcohol in liquid form the selective forces that led to such a
varied geographical distribution of this
characteristic. Variation in the capacity
to metabolise alcohol has also been
characterised among different species
of fruit flies. So addiction to alcohol,
in other words, may in part reflect
selective forces associated with past
exposure. Alcoholism has long been
known to run in families and to be
partially heritable, which is consistent
with this evolutionary scenario.
Nonetheless, health benefits can also
derive from low-level drinking, so we
have to be careful in any assessment of the
optimal levels of alcohol consumption.
Worldwide, most people do indeed drink
moderately, whereas a substantial fraction
of the global population is also reported,
for either genetic or cultural reasons,
to abstain from booze. The American
comedian Henny Youngman once
proclaimed: “When I read about the evils
of drinking, I gave up reading.” So the next
time you have a pint, or three, think about
the complex ecological interactions linking
tropical fruits, fermenting yeasts, and
primates. Your inner alcohol-loving beast
may be closer than you realise. �

With an abundance of alcohol


ROBERT DUDLEY is Professor of Integrative
available in the modern world, our
ancient genetic predisposition to Biology at the University of California, Berkeley,
it can become an addiction and author of The Drunken Monkey: Why We
Drink And Abuse Alcohol

JUNE 2014 / FOCUS / 79


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THE FUTURE OF G ADGE T S

TECHHUB
THIS MONTH
BILL THOMPSON
Robot writers
p83

JUST LANDED
Musical Fidelity V90
p84

ULTIMATE TEST
Smart cars
p87

EDITED BY DANIEL BENNETT

ON T HE HORIZON

XEROS
THE WATERLESS WASHING MACHINE
www.xeroscleaning.com, price TBC

ASHING YOUR CLOTHES

W
hasn’t changed a great deal in
the past 50 years or so. Now,
Sheffield-based company
Xeros could revolutionise
the way you do your washing,
replacing the water in your machine
with specially engineered beads.
Xeros CEO Bill Westwater explains.
“The idea came from the textile design
department at the University of Leeds.
Leeds, like a lot of northern universities,
used to work with textiles in a big
way. The researchers, led by chemist
Professor Stephen Burkinshaw, were
figuring out how to get dyes into
materials. And he thought, ‘If I know
how to do that, then I can reverse the
process. I’ll be able to get food stains
out instead.”
Burkinshaw’s insight led to the
development of the world’s first
bead-based washing machine, in which
millions of reusable nylon beads are
used to tackle dirt and stains. Although
the beads don’t replace detergent and
water completely, the system uses a
whopping 80 per cent less water than
the most economical conventional
washers. Or as Westwater puts it: “We
JUNE 2014 / FOCUS / 81
Tech Hub

TECHOMETER
Bill Westwater shows
off the polymer beads
that make Xeros work

WHAT’S HOT

VIRTUAL REALITY
Hoping to dominate our
virtual lives just as it already
dominates our real ones,
Facebook has just bought
the virtual reality headset
company Oculus Rift for
a cool $2bn. As well as
creating games for the
hardware, Facebook boss
Mark Zuckerberg hopes to
create “virtual experiences”
using the latest 360-degree
camera technology.

WHAT’S NOT
WINDOWS XP
Microsoft has ended its
support for Windows XP.
This means if your PC is
have proven that beads are a superior approximately 1.5 million of the 3-5mm running XP it’s likely to be
cleaning medium to water.” pellets. The total active surface area more vulnerable to hackers
It’s important first of all to understand is huge, particularly as care has been and viruses, since there
how a conventional washing machine taken to extrude the beads to a particular will be no future ‘fixes’. XP’s
works. “With a front-loading drum, you shape, size and density. simplicity and reliability have
have a puddle of water in the bottom, and There are a number of knock-on made it the OS of choice for
most cash machines, so an
paddles on the inside of the drum which benefits from the bead system. Because
alternative operating system
‘slap’ the clothes through the puddle as it lets you wash at a lower temperature,
will need to
they rotate,” says Westwater. “That’s a fabrics and colours that would normally
be found
crucial part of the cleaning process: it’s have to be separated can be washed soon.
always been about contact, right back together, and fabrics take longer to lose
to when people would scrub clothes by their bright colour. “A lot of our early
the riverbank. What we do is spray beads customers are people who wash rented
into the drum, showering the clothes workwear. If that takes longer to wear
with beads. This gives better physical out, people are saving money further
contact at all times.” down the line,” Westwater adds. READER POLL
Once the beads have made physical So when is this housework-slashing Would you buy a virtual reality headset
contact, their electrostatic charge draws device coming to our homes? “We have an made by Facebook?
the dirt particles in. The third angle of advanced-stage prototype in our labs for
attack in the beads’ favour is the fact that the domestic market,” says Westwater.
the nylon polymer becomes highly “We’ve been able to maintain the savings 35%
absorbent at 100 per cent humidity. in a smaller drum, but the truth is we Yes - it
ILLUSTRATOR: DEM ILLUSTRATION

doesn’t
When the nylon passes something called will be targeting American homes first matter who
the glass transition temperature, its because, as with everything else, they 65% it’s made by
No - I don’t
molecular structure becomes more use bigger machines.” want Facebook
amorphous and develops spaces in the running my
beads where dirt can accumulate. virtual life too
A typical 25kg industrial load of DANIEL BENNETT is reviews editor of
washing requires 50kg of beads – BBC Focus Magazine

82 / FOCUS / JUNE 2014


Tech Hub

THE NEXT BIG THING C OMING S OON


3 MONTHS

TESLA MODEL S
Said to herald the future of electric cars, the

ROBOT WRITERS Model S was a big hit in California last


year and a right-hand drive
model is making its way
to the UK this June.
very day waves of Teslamotors.com

E data wash over me,


mostly through my
laptop, tablet and
smartphone, and I
try to interpret, analyse and
Samsung NX
mini Smart Camera
Samsung has revealed the world’s slimmest
interchangeable lens camera. It will capture
20.5-megapixel shots and won’t put a
understand the world a crease in your pocket. Samsung.com
little better, hoping to turn
raw data into knowledge Apple Carplay
that can shape my life. Apple is coming to a car near you soon,
There’s more stuff out complete with apps and Siri, who’ll respond
there every day, and I’m to voice commands and read out your text
drowning in it. There’s the messages and emails. Apple.com
data I generate myself, like
where I go or the emails, 6 MONTHS
texts and tweets I send.
But that’s tiny compared MOTO 360
to weather details, medical Of all the smartwatches we’ve seen,
records, financial this is the first with a traditional
transactions, survey results circular face. Motorola’s device will
and the rest of the world’s be powered by Google Now, a digital
collected data. Making assistant that tracks your habits to
provide you with useful information.
sense of it all takes a lot of
moto360.motorola.com
effort, and highly paid
business analysts (and less
Sony 4K Short Throw Projector
highly paid journalists) This ultra HD projector creates 4m-wide
work hard to interpret and images from just a few centimetres away.
present the numbers in a The only drawback is that it costs $30,000
way that can be understood Narrative Science offers a processing power at either (£18,240). Sony.com
by non-specialists. service that will write up end of the conversation.
Unfortunately for them, your website’s Google Siri does a great job but it Audi Traffic Light System
it is starting to look like a Analytics data into reports literally is reading out the Audi will soon o�er a sat-nav system that
tells drivers what speed to maintain to avoid
well-trained algorithm can the marketing department phone book. It gets much
stopping at the next set of lights. Audi.com
do the job well enough for can understand. Its more exciting if you
most purposes. Companies QuillEngage tool turns imagine using it to read
like Arria and Narrative columns of statistics into these auto-generated 9 MONTHS
Science have developed sentences like: “Your site’s reports, or even answer
software that takes raw pages per visit for last week questions by searching vast MORPHEUS
data and turns out reports came to 3.4, the same as databases on the fly. Sony recently announced
and even news stories that your weekly average.” For now I only talk to my it’s been working on a virtual
do the job, even if they may This is exciting for a computer to plead with it reality headset. Early indicators
never win prizes for their number of reasons. First, or shout at it, and I don’t say the technology is solid
elegant prose. there’s now so much data and could provide real competition
expect it to listen. That may
for the Oculus Rift. Uk.playstation.com
Arria has done some out there that we’ll never be about to change, and
fascinating work in the oil have enough people or when it does we will soon
Project Ara
and gas industries and in resources to analyse and move way from tapping, Google is working on a modular phone that
hospitals, turning readings describe it all. Second, it swiping and pointing. would allow you to replace individual
into reports. NLG Engine, points to a future where we components, such as the battery or the
Arria’s ‘natural language work with computers in a camera, with better ones. It’s due for release
generation’ tool, writes care more human-like way. At BILL in 2015. Motorolaara.com
summaries of patient data the moment we interact THOMPSON
for doctors, and detailed with our computers in contributes to Kinect Shades
news.bbc.co.uk Microsoft has been developing virtual reality
weather forecasts from quite primitive ways, and the BBC glasses called Kinect Shades that would
meteorological data. And considering the enormous World Service power AR and VR games. Xbox.com

JUNE 2014 / FOCUS / 83


Tech Hub

JUST LANDED: MUSICAL FIDELITY V90 SERIES


MICRO MARVEL
Can you get true hi-fi sound
from a tiny separates system?
Daniel Bennett discovers that
size isn’t everything…

What is it? For its tiny size, the V90 outputs a


The best sound comes from hi-fi surprisingly big sound. If you have a
systems where each component is decent pair of speakers – I used a pair
isolated. Usually this equates to a of Dali Zensor 3 desktop speakers
rack of big black boxes, with a forest - the V90 amp and DAC will make your
of cables round the back. The V90 music sing. The mid-range is
series aims to undo all that. It’s a particularly strong, bringing lots of
complete separates system where detail to the honky-tonk piano in
each component has been shrunk Metronomy’s Love Letters. But this is
so that the whole stack takes up no intended as an entry-level system and
more space than a few books. as such the bass and treble output at
the extremes is limited: a track like
Is it easy to set up? James Blake’s Life Round Here, where
With each unit no bigger than a the electronic bassline is supposed to
Filofax, and with the number of throb while the vocals dance around
sockets and options kept to a bare on top, felt somewhat muted.
minimum, setup is quick and simple. We also had some slight issues
The digital-to-analogue converter setting up using a Mac, since the DAC
(DAC), which translates music from takes over volume control from the
digital 1s and 0s into an analogue computer. But we’re told this isn’t the
wave, can take music either via case with a PC, and it’s a pretty minor
USB or via the V90 Bluetooth frustration in any case.
receiver. The DAC is ‘plug and play’
so there’s no software to install Should I buy one?
before you start. From there, the The V90 system is an easy starting
DAC is plugged into the amplifiers point if you want to improve your
– the system includes dedicated digital music without giving over half
headphone and speaker amps. For your house to amplifiers, DACs,
vinyl fans, Musical Fidelity also pre-amps and the rest. It’s well
makes a V90 phono stage. designed, so it won’t be an eyesore.
and fewer buttons on the front. This suits my But its simplicity means the sound output is a
What’s it like to use? tiny o�ce just fine, but it won’t be useful for tad limited, so if you’re likely to get drawn into
This is a system for minimalists. There are those looking to connect multiple devices at the world of audiophile-grade equipment, it
very few inputs and outputs on the back once, like adding a Blu-ray player to the setup. might be worth spending a little more.

Actual Size:
170 mm
47 mm

POWER STATUS

Musical Fidelity V90: DAC/Bluetooth receiver/amplifier £199 each; headphone amp £169; phono stage £149; www.musicalfidelity.com

84 / FOCUS / JUNE 2014


Tech Hub

1 2 3

4 5

APPLIANCES OF SCIENCE
PAPERLESS FARMED RENEWED HOTTING BRIGHT SPACE
1 PLEASE 2 OUT 3 FOCUS 4 UP 5 IDEA 6 SAVER
Sony’s new Digital If astronauts can grow Regular readers will Another nail in the co�n Astronauts on the ISS An electric motor takes
Paper System wants to plants in space, then remember the Lytro for broadcast telly, Fire see 15 sunrises and up a lot less space than
liberate your o�ce from you can grow them right camera we tested in TV brings streaming sunsets every 24 a petrol one. This
its dependence on dead here on terra firma. issue 251, which let you services such as hours. So to help them battery-driven scooter
trees with an E-ink Inspired by NASA change the focus of a Netflix, iPlayer and, of get into some kind of uses the extra room to
tablet. This low-power technology, this picture after it had been course, Amazon Instant routine, scientists let its rider carry much
device lasts three miniature garden helps taken. Two years later, Video to your TV. But researched the more than they could on
weeks between you grow healthy plants the HTC M8 is the first unlike other streamers, optimum wavelength of a typical motorbike.
charges, lets you edit, indoors. You simply add smartphone to mimic it also o�ers streaming light for suppressing Where the fuel tank and
create and annotate some water to the this feature, using two videogames and a the sleep hormone engine would have been
documents, and at specially designed lenses at the rear of the dedicated games melatonin. Blue light there are now 23 litres
6.6mm thick is thinner solution – which is full phone to do the job. controller. And with proved best, which is of storage space. Fully
than your average of the optimum O2 and This means if you’ve Amazon’s purchasing why Light Science’s loaded and charged, it’ll
notepad. When you’re nitrate levels for growth accidentally focused power you can bet new Rhythm Downlight o�er a range of 70km
done working you can – and then leave the your photo on a lamp they’ll be able to o�er bulb uses blasts of – enough for most
upload your files to the smart pot and light to post rather than the access to most blue to keep you alert, commutes – and will
cloud via Wi-Fi or save work their magic. landscape behind it, you on-demand TV before followed by a relaxing even charge your
them to an SD card. Click And Grow Smart can correct the error the year’s out. tune when you need smartphone en route.
DPTS1 Digital Paper Herb Garden when you get home. Amazon Fire TV to rest. Feddz Electric Bike
System Clickandgrow.com, HTC M8 Amazon.co.uk, $99 Rhythm Downlight LED Feddz.de, $8,300
Pro.sony.com, price TBC $99.95 (£60.29) plus P&P HTC.com, £550 (£59), UK price TBC Lsgc.com, price TBC (£5,006)

JUNE 2014 / FOCUS / 85


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Tech Hub

ANT TO KNOW what

W
features your next
car might have? Then
you don’t need to
look much further
than the flagship
models of today. Like
a shop window,
manufacturers pack their smartest
wares into these machines to
showcase the technology and
design they intend to endow the rest
What technology will you find in of their cars with. From automated
driving to 360-degree cameras to
your next car? Daniel Bennett night vision mode, we test the four
test-drives the world’s smartest most high-tech cars on the road
today to find out what you
motors to find out might be driving tomorrow…

JUNE 2014 / FOCUS / 87


Tech Hub

BMW M4
From £56,635, www.bmw.co.uk

THESE DAYS, A good measure of built-in web browser too, which is


whether something’s ‘modern’ or less snappy, but a welcome
not is whether it has its own app. addition should you need to look
The M4 has two. Between them something up. Once your
they can access your social destination is primed, the
networks, podcasts and show you directions also pop up on your
where you parked your car (though windscreen via a Heads-Up
we’d hope not to need that feature Display (HUD), along with a
too often). The most useful thing of progress bar that fills up as you
all they can do is pick apart the close in on the next turn. This
telemetry from your car’s engine to means you rarely have to take your
tell you how you’ve been driving eyes o� the road.
and precisely what to do to start While you drive, the cameras are
saving some money on petrol. also busy reading the nearest road FASTER SOUNDS
Following the app’s instructions, signs to project the current speed The M4 will let you stream music from an ever-growing
we gained an extra 5mpg. limit alongside your actual speed number of online stores and internet radio stations
The computer onboard the car on the HUD. These cameras also
itself was easily the most intuitive work with radar detectors on the
to use. It blinked between menu nose and rear end of the M4 to ENGINE SIZE 2,979 CC
screens instantly, with all the help you park. They actually
options oriented around a single highlight obstacles as you HORSEPOWER 431HP @ 5,500 RPM
dial while keeping the sat-nav approach them, going from green
displayed on the right-hand side of to red as you get nearer. MPG* 32.1 MPG
the screen at all times. There was BMW’s o�ering might not be as
hardly any waiting around when pioneering as the Mercedes, but it 0-60MPH* 4.3 seconds
we used Google maps data to find pulls o� everything it does o�er
us the nearest pub to a small B supremely well. DIMENSIONS 4.7 X 1.9 X 1.4M, 1,612KG
road in south Wales. There’s a QQQQQ
*Manufacturer’s quoted figures
PHOTO: THESECRETSTUDIO.NET

88 / FOCUS / JUNE 2014


Tech Hub

AUDI A8
From £62,765, www.audi.co.uk

THE A8 IS elegant and understated. stations quickly. Your sat-nav


In fact, before the keys landed in directions are then beamed onto
our hands it had been chau�euring the windscreen by the car’s HUD,
celebs to and from the BAFTA along with safety warnings if you
awards. Inside, the ergonomics of start getting too close to the car in
every button, stick and switch front. There’s even an update
have carefully thought out. For coming which will be able to tell
example, since the gear lever is flat you what speed to maintain to
like a boat’s throttle, it’s where avoid having to stop at the next
you’ll naturally rest your left hand. tra�c light – thus saving you fuel.
Knowing this, Audi has placed all And the 360-degree camera, which
the most used controls a finger’s takes radar images from around
stretch away from this spot. the car and compiles them into a
TRACKING TRAFFIC The same design ethos runs into top-down view, means parking will
Future Audis will include a system that tells the driver how the intuitive Audi Connect system, never be di�cult again.
fast to travel to avoid stopping at the next set of lights which manages the car’s settings, Unlike the other cars, the A8
sat-nav and multimedia. For drinks diesel. It’s also a relatively
instance, you can input addresses small three-litre engine block, but
ENGINE SIZE 2,967 CC and postcodes by drawing them Audi has clearly taken the lessons
out with your finger on the central it’s learned beating petrol cars in
HORSEPOWER 255 HP @ 4,000RPM touchpad. It’s much quicker than 24-hour races and put them to
relying on the car’s central good use. It can be frugal and quiet
MPG* 47.1 MPG ‘jogwheel’, and it successfully one second, ferociously fast the
translated our crude chicken next, while the four-wheel drive
0-60MPH* 6.1 seconds scratching into letters. Once the system makes you feel glued to the
car pulls away, the touchpad road at all times, and forget you’re
DIMENSIONS 5.3 X 1.9 X 1.5M, 2,585KG displays the numbers 1-6 so you in something the size of a yacht.
can select your favourite radio QQQQQ

JUNE 2014 / FOCUS / 89


Tech Hub

LEXUS
LS 600H
From £99,995, www.lexus.co.uk

PANELLED WITH WALNUT and very job – keep everything serene.


draped in leather, the LS 600h has The LS 600h was the car in which
all the opulence of a stately home. we felt most isolated from the
But beneath the old-fashioned outside world. Even on the noisy,
demeanour is a strikingly modern potholed M25, the inside of the
petrol-electric hybrid engine – cabin was relatively sedate.
similar in a sense to what you’d find Again, the car is always
in a Toyota Prius. casting a watchful eye over the
Tacking an electric motor onto road. Radar that is sensitive
a five-litre V8 might seem futile enough to pick up individual
ecologically speaking (though we pedestrians monitors the adjacent
did average around 28mpg), but it’s lanes and sends out a warning if
not there to save the planet. What you start to switch lanes without
it is there to do is move quickly and checking your blind spot – all the ACQUIRING APPS
silently. Unlike a petrol engine, the while monitoring the car in front in The LS 600h can be improved with apps that give you
battery-powered motor, which is case it needs to ready the brakes access to local information and radio from around the world
charged from the wheels when the and safety systems for a crash.
car coasts, can deliver all of its Unfortunately, the on-board
power the second you stamp your computer isn’t as smart or as ENGINE SIZE 4,696 CC
foot on the pedal. This means if you relaxing to use as the rest of the
need to move all 2.8 tonnes of the car. It’s controlled via a small HORSEPOWER 389HP @ 6,400 RPM
car in a hurry, you don’t need to joystick, which more often than not
wait for the petrol engine to reach causes you to glide over the option MPG* 32.8 MPG
its peak rev range. And since this is you wanted. Generally speaking it
a bit of a limousine it doesn’t hurt slows everything down, and puts 0-60MPH* 6.2 seconds
that it’ll do all this silently, too. you o� using the clever features
Most of the technology packed behind its 12-inch display. DIMENSIONS 5.2 X 1.9 X 1.5M, 2,815KG
throughout is channelled to do that QQQQQ
PHOTO: THESECRETSTUDIO.NET

90 / FOCUS / JUNE 2014


Tech Hub

MERCEDES
S500 AMG L
From £88,130, www.mercedes-benz.co.uk

THIS IS EASILY one of the most After dark, an infrared camera


advanced machines I’ve ever behind the radiator keeps watch.
experienced. On the surface, the You can monitor this from the dash,
luxuries are easy to spot. A but the car is always looking for
vaporiser di�uses perfume, the animals or people in the road. If a
chairs give hot stone massages person steps out the car flashes its
and the sound system pumps out headlights, but if the car detects an
pin-sharp music. But strip away animal on the tarmac, it only warns
these extravagances, and the S500 you, for fear of startling the animal.
is still miles ahead of its rivals. The S500 will even do the
Intelligence seems to be wired driving for you. On motorways, we
into the very chassis of the S500. engaged the Distronic Plus system
A pair of cameras behind the rear – a kind of robotic chau�eur –
PRECISION PARKING view mirror scan the road ahead, which steered the S500 between
The S500 uses cameras around the car to display your exact scouting for bumps and potholes. the white lines at a constant speed,
position from above, as well as the view from the rear camera When they find one, the whole only slowing when the car in front
body leans over to one side to got closer. We kept our hands on
reduce the impact – the car the wheel, but otherwise just sat
ENGINE SIZE 2,967 CC genuinely seemed to glide over back and enjoyed the ride – for
speed bumps. These cameras also several hundred miles.
HORSEPOWER 255 HP @ 4,000RPM keep an eye on the car in front: the In truth, we’d need a few more
S500’s computer will spot an pages to fit in all the tech found
MPG* 47.1 MPG accident before you can, and ready inside the S500, like the blind spot
the brakes in anticipation. Fail to warnings, the 360-degree parking
0-60MPH* 6.1 seconds react and the car will sound camera and more. For now all we
warnings before hitting the brakes can say is that we hope this is
DIMENSIONS 5.3 X 1.9 X 1.5M, 2,585KG for you. Thankfully we didn’t have where car technology is heading.
to test this out! QQQQQ

INTERACTIVE
360° PANORAMAS
IN OUR iPAD APP

JUNE 2014 / FOCUS / 91


HOW DO WE KNOW?

THE UNIVERSE STARTED WITH A

BIG BANG BY JOHN GRIBBIN


Finding the heat signature of a cataclysmic explosion turned out to
be proof that our Universe expanded from a single point. It would prove
be one of humanity’s greatest discoveries

HE IDEA THAT the Universe perhaps ‘bouncing’ into another cycle number equal to tens of billions
was born in a hot, dense state of expansion and collapse. At the time,

T
of usual years.’ This is pretty close
– the Big Bang, as Fred Hoyle there was no firm evidence that any of to the accepted modern value, 13.8
dubbed it – is one of the most these mathematical models matched billion years, but nobody took any
important, and well-established, the Universe in which we live. notice at the time.
scientific concepts. But the But that didn’t stop Friedmann
idea is less than a hundred speculating. In a book, World As Space
years old, and The Beatles And Time, published in 1923, he wrote: GALAXIES OR NEBULAE?
were already the singing ‘It is useless, due to the lack of reliable What Friedmann didn’t know was
sensation of the 1960s before astronomical data, to cite any numbers that there was already astronomical
astronomers had proof that there that describe the life of our Universe. data that supported his idea. At the
really was a Big Bang. Fifty years ago Yet if we compute, for the sake of Lowell Observatory in America, Vesto
this summer, solid evidence was found curiosity, the time when the Universe Melvin Slipher (always ‘VM’ to his
in the form of the so-called Cosmic was created from a point to its present colleagues) had been studying the light
Microwave Background Radiation. By state, ie, time that has passed from the from objects then known as nebulae
then, though, there was already plenty ‘creation of the world,’ then we get a – spiral ‘clouds’ of material. There
of circumstantial evidence. was a debate about whether these
With hindsight, we can see the were clouds of gas within the Milky
genesis of the Big Bang idea in a Way, perhaps sites of star formation,
paper published by the Russian or much larger objects far beyond the
mathematician Alexander Friedmann Milky Way – galaxies (as we now call
in 1922. Friedmann realised that them) in their own right.
the equations of Albert Einstein’s To his surprise, Slipher found that
General Theory of Relativity, which the light from these spiral nebulae is
PHOTO: SCIENCE PHOTO LIBRARY X2

describe the behaviour of space, ‘redshifted’, by a large amount (see ‘Need


time and matter, allowed for the to know’ p95). The naive explanation
possible existence of different kinds of for this was that the objects are
universe. Some started out small and moving rapidly away from us, and the
expanded as time passed. Some started redshifts are caused by the Doppler
large and shrank as time passed. Some effect. This suggested that they were
grew from a tiny point out to a certain A map of the Cosmic Microwave Background indeed beyond the Milky Way.
size then collapsed back into a point, - the afterglow radiation of the Big Bang But there is another possibility. In

92 / FOCUS / JUNE 2014


How do we know?

> IN A NUTSHELL
How the Universe began was one
of the biggest questions facing
science. Over the course of the
20th Century, a series of
astronomical observations and
The Universe was born from a single
point in time and space, a discovery fortuitous physics experiments
made possible by identifying the finally verified the Big Bang theory.
radiation from the Big Bang itself

JUNE 2014 / FOCUS / 93


How do we know?

the expanding Universe models for all that the spirals were indeed work. So when he independently
discovered by Friedmann (but galaxies far out into the Universe. discovered the same solutions to
which Slipher knew nothing of), a The time was ripe for someone to Einstein’s equations that Friedmann
similar redshift effect is produced by put redshifts and distances together, had found, his interpretation of the
the stretching of space as time passes. adding in the equations of the General equations was based on observations of
The debate about the nature of the Theory of Relativity to provide a the real Universe. Putting everything
spiral nebulae was resolved in 1924. description of our Universe. together, and estimating the distances
Edwin Hubble, working at the That someone was Georges to galaxies by a rule of thumb that
then-new 100-inch telescope at Mount Lemaître, a Belgian mathematician fainter galaxies must be further away
Wilson in California, which was far and astronomer who added two and than brighter galaxies, he discovered
more powerful than the telescope two to make four. Lemaître, although that the redshift of a galaxy depends on
Slipher had, was able to measure the based in Belgium, had visited its distance from us – its ‘velocity’ is
distance to the Andromeda Nebula (or Cambridge in England, Harvard, and proportional to its distance. But he
galaxy) by studying variable stars Mount Wilson. He had met both was aware that this is not a Doppler
known as Cepheids within the ‘nebula’. Slipher and Hubble, and was up to effect. As he put it in 1927, the
This, and measurements of distances date on all the observations, but redshifts are ‘a cosmical effect of the
to other nebulae, established once and completely unaware of Friedmann’s expansion of the Universe’.

THE KEY A baffling find by Penzias and Wilson that the Universe was warmer than it should be at
EXPERIMENT their radio antenna turned out to be a major discovery that would earn them a Nobel Prize

THE HORN ANTENNA at Crawford Hill in New to calibrate the system. By switching the The pair did everything they could think
Jersey was built for use with satellites, so antenna from observations of the cold of to remove any sources of interference,
the shape of it was designed to minimise load to observations of the sky, they could including cleaning out the layer of droppings
interference from the ground, and provide measure the apparent temperature of that had accumulated in the antenna horn
the best possible measurement of the the Universe (expected to be 0 Kelvin) then from a pair of nesting pigeons. Nothing
strength of radio noise from the sky. The subtract out known factors, such as the made much di�erence. The mystery of the
nature of this radiation depends on the interference from the atmosphere above. ‘excess antenna temperature’ continued to
temperature of the radiating object. The But in 1964 it soon became clear that the ba�e them throughout 1964.
amplifiers used in the receiver were cooled radiation coming from the That is until they realised, with the help
to 4.2K (-268.8°C) using liquid helium, and antenna into the receiver of Dicke, Peebles, Roll and Wilkinson at
Penzias devised a ‘cold load’, cooled by was at least 2K hotter Princeton University, that they were looking
liquid helium to about 5K, which was used than they could explain. at the afterglow radiation of the Big Bang.
PHOTO: GETTY X3, CORBIS, SCIENCE PHOTO LIBRARY, NASA

Robert Wilson (left) and Arno Penzias (right) in front of the antenna that fortuitously picked up the heat signature of the Cosmic Microwave Background

94 / FOCUS / JUNE 2014


How do we know?

This discovery – which really


ought to be known as Lemaître’s Law
– was published in a paper whose CAST OF It was Lemaître’s initial brilliance that enabled
title translates as ‘A Homogeneous CHARACTERS others to prove the Big Bang theory
Universe of Constant Mass and
Increasing Radius Accounting for the
Radial Velocities of Extra-Galactic Georges Lemaître
Nebulae’. He also worked out the (1894-1966) was a
relationship between redshift and Belgian astronomer, and
distance, coming up with a figure of also an ordained priest,
575km per second per Megaparsec who worked at Louvain
for what is now known as Hubble’s University. He was the
constant (for reasons that will become first person to suggest
clear). So a galaxy 1Mpc away is that the Universe
receding at 575km/s; a galaxy at started from a hot,
a distance of 2Mpc is receding at George Gamow superdense state, which
1,150km/s, and so on. But Lemaître’s (1904-1968) was a he called the ‘primeval
1927 paper was published in an Russian-born American atom’. He discovered
obscure Belgian journal, and nobody astronomer, based in the rule now known as
noticed it – even though he sent a copy Washington, who ‘Hubble’s law’ two years
to the leading British astronomer of developed Lemaître’s before Hubble.
the day, Arthur Eddington. idea and promoted it in
the 1940s and 1950s.
His students Ralph
HUBBLE IN A HURRY Alpher and Robert
Meanwhile, Hubble had been busy. Herman calculated that
He recruited a more junior astronomer the radiation from the
(but the best observer in the world), primeval fireball should Arno Penzias (1933- )
Milton Humason, to measure redshifts fill the Universe at is a German-born
of galaxies, while Hubble measured a temperature of a American astronomer
distances by a variety of techniques. In few Kelvin, but who worked at Bell
1929, Hubble and Humason published the prediction Laboratories. Most
a paper based on a study of 24 galaxies, was forgotten. of his work dealt
20 of which had redshifts measured by with developing
Slipher, and four with ‘new’ redshifts instrumentation for
obtained by Humason. radio astronomy and
This was enough for Hubble to satellite communication
publish the now-famous discovery but in 1964, working
of the redshift-distance relationship. with Robert Wilson, he
It showed that the distance of a galaxy accidentally discovered
from us is directly proportional to the the background radiation
velocity implied by its redshift. This – Robert Wilson that Gamow’s team had
exactly what Lemaître had published (1936- ) predicted more than a
two years earlier – became known is another American decade earlier.
as ‘Hubble’s Law’. The value of the radio astronomer
Hubble constant in the Hubble and who worked at Bell
Humason paper was 500km/s per Laboratories. As
Mpc, suspiciously close to Lemaître’s a student he was David Wilkinson
value. There was no mention in that strongly influenced (1935-2002)
paper, though, of either Slipher or by Fred Hoyle, and was an American
Lemaître. Hubble, a notoriously became a supporter astrophysicist who
vain and unpleasant self-publicist, of the Steady State devoted his career
did everything he could to take all model of the Universe. largely to the
the credit and glory, and to a large Ironically, he shared investigation of the
extent succeeded. the Nobel Prize with cosmic microwave
This time, the news spread like Penzias in 1978 for background radiation
wildfire. Lemaître, understandably making the discovery after its discovery.
miffed, wrote to Eddington reminding that killed o� the Nobody made a greater
him of the 1927 paper, and Eddington Steady State model. contribution to the field
did everything he could to spread the over the next 30 years,
news of Lemaître’s priority, including and the Wilkinson
getting a translation of the paper Microwave Anisotropy
published in English. Lemaître Probe satellite (WMAP)
did eventually get the credit he was named in his honour.

JUNE 2014 / FOCUS / 95


How do we know?

deserved. But it was Hubble who


got the law named after him.
It could be the biggest question of all: how did the
TIMELINE Universe begin? It took decades of discovery to answer
Lemaître, though, wasn’t finished.
Hubble was only interested in using
redshifts to measure distances,
and never tried to fit them to any
cosmological model. Most relativists
Edwin Hubble discovers simply regarded the equations
that the distance of a as something to play with, of no
galaxy from us is directly relevance to the real world. Lemaître,
proportional to the
velocity implied by its
though, took them at face value and
redshift. Lemaître had
published this in 1927, but
nobody had noticed.
1929 used them to attempt a description of
how the Universe began. In 1931, he
speculated that the Universe might
have begun violently (in ‘fireworks’)
in a very dense state, which expanded
Lemaître writes in dramatically to become the world as
Nature: ‘We could we see it today. He developed these
conceive the beginning
ideas in a book published in 1946,
1931 of the Universe in the
form of a unique atom,
the atomic weight of
and referred to the origin of the
Universe either as the ‘primeval atom’
which is the total mass or the ‘cosmic egg’. This inspired
of the Universe.’ the Russian-born American George
Gamow to take up the idea and
develop it further, with the aid of
his colleagues Ralph Alpher and
Alpher (pictured) and
Herman calculate
Robert Herman.
that the leftover
radiation from the 1948 Ralph Alpher realised that the
heat from Lemaître’s ‘fireworks’
primeval fireball should have filled the Universe with
should still fill the electromagnetic radiation, which
Universe today, with a would still exist today in the form of
temperature of about
5K. This was also
cold radio waves. In 1948, he published
a paper in Nature concluding that
1964 published in Nature.
‘the temperature in the Universe at
the present time is found to be about
5 Kelvin [–268°C].’ Gamow promoted
Penzias and Wilson discover a weak hiss of the idea for a time (and now often
radio noise coming from all directions in space. incorrectly gets the credit for it),
The following year this is explained as the but in those days nobody thought
leftover radiation from the Big Bang.
that such cosmic background radiation
could be detected, and the idea
was soon forgotten.

BIG BANG QUANDARIES


But there was a problem with the
1989 Big Bang idea, as it was being called
by the 1950s. The speed with which
Launch of the Cosmic Background Explorer galaxies are moving apart today
satellite (COBE), which detected tiny irregularities
(ripples) in the background radiation, confirming
tells us how long it has been since
the accuracy of the Big Bang model. they were all squeezed together in
PHOTO: GETTY, SCIENCE PHOTO LIBRARY, NASA X3

Lemaître’s cosmic egg. This ‘age of


the Universe’ is related to Hubble’s
constant – the bigger the constant, the
Launch of the Wilkinson faster the galaxies are separating and
Microwave Anisotropy
Probe (WMAP), which
the younger the Universe. For a value
makes precision of 500km/s per Mpc, the Universe

2001 measurements of the


background radiation,
pinning the age of the
would only be about a billion years
old – far younger than the known ages
of the Sun and stars. This encouraged
Universe down as 13.8 the rival Steady State model of the
billion years.
Universe, which says that the Universe
has always existed and always expands

96 / FOCUS / JUNE 2014


How do we know?

JARGON BUSTER
The cosmic terms you’ll need to
understand the Big Bang

COSMOLOGICAL REDSHIFT
A stretching of light, or other electromagnetic
radiation, caused by the stretching of
space between the galaxies as a result of
the expansion of the Universe. This is not a
Doppler e�ect, because it does not involve
motion through space, but is measured in
units of velocity. The cosmic background
radiation is light from the Big Bang with a
redshift of 1,000.

HUBBLE’S LAW
Actually first discovered by Lemaître, the
law says that the redshift ‘velocity’ of a
galaxy is proportional to its distance. So a
galaxy twice as far away is receding twice
as fast, and so on. This does not mean we
are at the centre of the Universe, however.
The law works the same way whichever
galaxy you observe from.

MICROWAVES
The light from Pandora’s Cluster – a group of galaxies in the deepest realms of the observable Universe – has been
Microwaves are radio waves with shifted to the red end of the spectrum due to the expansion of the Universe
wavelengths in the range from 1-30cm.
In astronomy they’re used to study instruments no matter which part of with ‘A Measurement of Excess Antenna
the background radiation left over the sky they pointed the telescope to. Temperature at 4,080 Mc/s’, making
from the Big Bang, and in the study of They were utterly baffled. Then, in no mention of the possible significance
interstellar molecules. On Earth they’re December 1964, Penzias happened of the discovery except for the sentence
used in microwave ovens, radar and to mention the problem to another ‘A possible explanation for the observed
telecommunications. The Universe is radio astronomer, Bernard Burke, excess noise temperature is the one
a microwave oven with a temperature who said that he knew of a team at given by Dicke, Peebles, Roll and
of -270.3°C. Princeton University (a 30-minute Wilkinson in a companion letter in this
drive away) who might shed some issue.’ It was the proof that there really
light on the problem. was a Big Bang.
but that new atoms pop into existence That team was headed by Jim In the following decades, three key
as space stretches to make new Peebles and Robert Dicke, with two satellites probed details of the Big
galaxies which fill the gaps. junior colleagues, Peter Roll and David Bang. The first was COBE, launched
The Big Bang idea gradually became Wilkinson. Dicke had independently in 1989, which detected ripples in the
more respectable as better telescopes come up with the same idea as Ralph background radiation produced by the
and improved observations showed Alpher, but had gone one step further seeds on which galaxies grew. The Big
that the Hubble constant is much by initiating a project to build a Bang theory had triumphed. �
smaller than Lemaître and Hubble telescope to look for the predicted
had estimated – less than 100km/s per radiation. The telescope was nearly
Mpc. Then came the decisive moment. complete when Penzias and Wilson JOHN GRIBBIN is a visiting fellow in
In 1964, Arno Penzias and Robert got in touch. The two teams put their astronomy at the University of Sussex,
Wilson were adapting a radio telescope heads together, and quickly established and author of Science: A History
built to test satellite communications that what Penzias and Wilson had
for radio astronomy. The telescope, at found could indeed be the ‘echo of the Find out more
Crawford Hill in New Jersey, belonged Big Bang’. They produced a pair of Listen to ‘The Age Of The
to the Bell telephone company. Before papers in the July 1965 issue of the Universe’, an episode of In
it could be used for astronomy, it had Astrophysical Journal. Dicke, Peebles, Our Time, in which Melvyn
to be calibrated. Penzias and Wilson Roll and Wilkinson came first, setting Bragg discusses how we came to discover
found that it was plagued by what out the theory of leftover radiation the Big Bang with Astronomer Royal Martin
seemed to be interference. A weak from a hot early Universe. That paper Rees. http://bbc.in/LNnjG0
hiss of radio noise showed up in the was followed by Penzias and Wilson

JUNE 2014 / FOCUS / 97


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FOC114S

FOC114IT

FOC114
To Do List

TO DO LIST
WATCH
LISTEN
TOUCH
VISIT
PLAN YOUR MONTH AHEAD WITH OUR EXPERT GUIDE READ
PICK OF THE MONTH DON’T MISS!
From the works of Buckminster Fuller (left)
through to the Space Age and the discovery
of the Higgs boson (right), Horizon has
covered a remarkable 50 years of science

Inside The
Wildfire
Kate Humble travels Down
Under to discover how
bush fires start. p100

Horizon’s 50th anniversary


IF SOMEONE FROM 1964 was catapulted into launch a grand scientific challenge. Coming 300 Cheltenham
the present day, they’d be in for a shock. In
the past half-century, we’ve landed people on the
years after the Longitude Prize – a reward offered
by the Government to whoever could come up with
Science Festival
Moon, sequenced the human genome, discovered a way to determine a ship’s longitude – the prize will With talks from the likes of
the Higgs boson and learnt how to share novelty cat see Horizon viewers being asked to choose from a Kevin Fong, Alice Roberts
videos using a globe-straddling network of bleeping, list of six of science’s biggest problems – details of and Richard Dawkins, it’s
blooping gadgets. which are still under wraps at the time of writing. set to be a great week of
How would you go about explaining the myriad The search for a solution will be launched in science events. p103
transformations that have revolutionised our world May on BBC Two by presenter Alice Roberts. The
since 1964? Well, you could do worse then asking winner will bag a whopping £10 million to help them
them to watch the entire back catalogue of Horizon – achieve their dream – so if you fancy yourself as
the BBC’s flagship science series which this month the next Elon Musk or Richard Branson, now might
celebrates its 50th birthday. be your moment.
Since its very first episode in May 1964 exploring In the meantime, Horizon will return to our
the world of inventor and entrepreneur Buckminster television screens later this year for its 51st series.
Fuller, Horizon has been on hand to guide us through Here’s to another 50 years!
science’s most captivating stories, revealing some JAMES LLOYD
PHOTO: ALAMY, NASA, CERN

of the personalities behind the theories. Few will


forget Andrew Wiles’s teary-eyed recollection, in Do No Harm
an award-winning 1996 episode, of the moment he Acclaimed neurosurgeon
Horizon’s £10 million
realised he’d solved one of the world’s most difficult Henry Marsh recounts
challenge will launch on
maths puzzles: Fermat’s Last Theorem. what it’s like to operate on
BBC Two in mid-May
Today, Horizon is still going strong, and to the most complex organ:
celebrate its 50th, it’s teaming up with Nesta to the human brain. p104

JUNE 2014 / FOCUS / 99


To Do List

WATCH
TV, DVD, BLU-RAY & ONLINE
WITH TIMANDRA HARKNESS

MAY EDITOR'S
CHOICE

Mythbusters
Discovery, May TBC

ADAM SAVAGE AND Jamie Hyneman


are back with their intrepid team
and another batch of myths, both
urban and Hollywood, to bust. Can
true love withstand any obstacle?
Did the world emerge from a giant
goose egg? Nah, only kidding – it’s
just the usual stu� with motorbikes,
explosions and throwing crash test
dummies o� tall buildings.

FROM 3 MAY

The Numbers Game 2


National Geographic, 7pm

DATA SCIENTIST JAKE Porway


returns with more stats-based fun.
What are the statistics of luck, and
how superstitious are you? Are
you a hero or a bystander? Jake No Kate Humbles
PHOTO: DISCOVERY NETWORKS X2, UKTV X2, NATIONAL GEOGRAPHIC CHANNEL, THINKSTOCK, PRESS ASSOCIATION, BBC

stages some social experiments to were harmed in the


making of this image
investigate the di�erence between
the one in five of us who will perform
an act of heroism in our lifetime, and 1 JUNE
the other 80 per cent who won’t.

5 MAY
Inside The Wildfire
BBC Two, time TBC

Tomorrow’s World BUSH FIRES ARE a constant 10m-high flames to scare Kate
Eden, 7pm menace in Australia. They’re Humble, though. For this two-
part of the continent’s part special she went Down
LIZ BONNIN MEETS the inventors, ecosystem – but they’re not Under to find out how these
engineers and dreamers who could very compatible with human fires start, how they spread
shape our high-tech future in this settlement. Hundreds of people and how to fight them.
one-o� film. Do we have the right have died, and thousands more As well as courage and
economic and scientific environment dispossessed, as the flames community spirit, the locals
to nurture a new industrial devoured their homes. have science on their side. Kate
revolution? Nanotechnology and the The summer of 2013-14 was speaks to experts from around
entrepreneurial race into space are predicted to be particularly the world, finds out about the
just two of the promising fields in bad for fires. Heatwaves and new ‘Richter scale’ for fire,
which our imagination takes root. lightning storms provide the and visits the pyrotron - not
perfect conditions for deadly an evil robot that likes to set
blazes on a scale so vast that a things alight, but a fireproof
TIMANDRA HARKNESS is a stand-up comedian and a presenter on fire can create its own weather wind tunnel used to study the
BBC Worldwide’s YouTube channel Head Squeeze system. It takes more than mechanics of how fires spread.

100 / FOCUS / JUNE 2014


To Do List

18 MAY
DVD & BLU-RAY
The Cave
Discovery, 10pm Natural History Museum Alive
Go Entertain, £12.50, DVD
WE’VE HAD VICTORIAN farms and
Tudor kitchens, and in 1978 the DAVID ATTENBOROUGH GETS his own night in
BBC’s Living In The Past sent 13 London’s famous museum, with expert input from
volunteers back to the Iron Age for a curators and resident scientists, and CGI to bring
whole year. Now, 10 volunteers are the long-dead beasts to life.
being sent back to the Stone Age to
live like our most distant ancestors.
If you feel vulnerable without your
smartphone, imagine life with no
Monkey Planet
Spirit Entertainment, £19.99, DVD
metal tools, no books and no beer.
DR GEORGE MCGAVIN is our guide on this three-
19 MAY hour journey into the lives of primates. From
lemurs to our closest cousins, the great apes,
Ice Age Giants meet our extended family from Africa to Japan.
Eden, 5pm

STEP BACK IN time to an era 40,000 ONLINE


years ago, when thick ice covered
the Earth, mammoths roamed the YOUTUBE
snowy tundra and pretty much
everything was woolly – even The Mathematics Of Love
the rhinos, as Prof Alice Roberts youtube.com/watch?v=N37x4GgDVBM
reveals. Archaeology and dramatic DR HANNAH FRY, a
visualisations take us back to the mathematician and
time of the sabre-toothed cat, the complexity scientist at UCL,
ground sloth and the Glyptodont. breaks down the maths of
finding a perfect partner in
this TEDx Binghampton talk.
25 MAY
Are your odds of success
really just 1 in 285,000?
Curiosity: What Destroyed The Hindenburg?
Discovery, 10pm
YOUTUBE
What caused the
notorious Hindenburg Amazing Bead Chain Experiment
disaster of 1937? youtube.com/watch?v=6ukMId5fIi0
PHYSICIST AND COMEDIAN
Steve Mould and his
apparently gravity-defying
bead chain are shown in
slow motion and explained
by science – though they
invite discussion of other
theories in the Comments.

YOUTUBE

The Science Of Gender And Science


THE CATASTROPHIC CRASH of the Hindenburg airship youtube.com/watch?v=9bTKRkmwtGY
in 1937 probably changed the course of aviation
history. Only now are lighter-than-air aircraft being seriously IN THIS TWO-HOUR debate,
considered as rivals to aeroplanes. But what caused the psychology professors
disaster? To find out, aeronautical engineers build 50-foot Steven Pinker and Elizabeth
replicas of the Hindenburg to test the leading theories in a Spelke discuss the reasons
spectacular series of experiments. But will this reassure you why the sexes tend to
that such a conflagration can never happen again, or have perform di�erently in maths
you running for cover every time a blimp appears overhead? and science. Can science
explain the disparity?

JUNE 2014 / FOCUS / 101


To Do List

LISTEN
BBC RADIO PROGRAMMES
TOUCH
SMARTPHONE & TABLET APPS
WITH TIMANDRA HARKNESS WITH CHRISTOPHER BRENNAN

FROM 27 MAY MAY


Element Bank: Periodic Table
Android 2.1 or later, AppByte, £0.99
The Life Scientific Inside Science
BBC Radio 4, 9am BBC Radio 4, Thursdays, 4.30pm AS YOU CAN probably guess from
the name, this app shows o� the
THE RETURN OF Jim Al-Khalili’s A ROSTER OF hosts including periodic table. With the table shown
conversational series. Each Adam Rutherford, Lucie Green, full screen you simply tap to see the
week he chats with a fellow Alice Roberts and Tracey Logan pertinent details. Atomic number,
scientist about their life, their delve into the science stories melting point, boiling point and
work and what makes them that are breaking or about to atomic weight are just a few of the details on o�er. Included with
tick. One day he must run out of break each week – as well as each description is an image of the element or the person who
engaging people whose work looking at some of the stories discovered it. A sweet final touch is the inclusion of a recording of
has shaped our world, but it behind the headlines that you The Element Song by Tom Lehrer, complete with lyrics.
hasn’t happened yet. don’t usually hear.
MAY
MAY
DIY Sun Science
Infinite Monkey Cage iPhone, iPad, iPod touch, iOS 6.0 or later
BBC Radio 4, dates/times TBC Living World Lawrence Hall of Science, free
BBC Radio 4, Sundays, 6.30am
THIS FANTASTIC APP lets you
INTRIGUING, INTIMATE RADIO learn all about the Sun without
portraits of British wildlife. The putting your eyesight at risk.
challenge of making snakes and Chock full of images and video
plants into engaging radio has from a variety of sources, you’ll
surprisingly proved no obstacle see our star in a whole new light.
to this series. We are most For example, one video charts
looking forward to the snail changes from 1996 through to the
shell-nesting bees on 18 May. present day using images from
Brian Cox (infinite monkeys not shown) the SOHO Satellite. The app allows
you to observe the Sun ‘live’ on-screen through a variety of filters.
BRIAN COX AND Robin Ince There are also some built-in activities to help you and your children
return with another series of the learn more about how the Sun a�ects life here on Earth.
show that locks science and
comedy in a room with a live
studio audience to discover
what emerges. It’s not Meet Science: Magnetism And Electricity
technically set in a cage, and iPad, iOS 6.0 or later, NCSOFT, £2.49
there are no actual monkeys,
but it hasn’t ended yet so that’s Wool carder bees are prone to making PERFORM HOMEMADE
one out of three... their homes in discarded snail shells experiments to learn about
magnetism and electricity with
this cool iPad app. With a series
PHOTO: BBC, ALAMY, THINKSTOCK, BRITISH MUSEUM

ONLINE: IPLAYER of work-through information


screens and quizzes, you learn as
you go, testing your knowledge at
A Brief History Of Mathematics the end. The experiments can all
bbc.co.uk/programmes/b00srz5b/episodes/player be done with items you can find
around the home or get hold of easily, and range from the relatively
RECENTLY REPEATED ON BBC Radio 4, simple ‘bending water with static electricity’ to building your own
PHOTO: NASA/WMAP

each of Prof Marcus du Sautoy’s forays speaker. Naturally, this app is fun for kids, but the adults aren’t left
into the history of maths lasts 15 minutes and out either. A great family-based learning tool.
features mathematicians, their ideas and their
legacy – from philosophy to space travel.
CHRISTOPHER BRENNAN is a technology journalist and app expert

102 / FOCUS / JUNE 2014


To Do List

VISIT
EVENTS & EXHIBITIONS
WITH JHENI OSMAN

8 MAY

How To Rebuild The World From Scratch


Royal Institution, London, 7pm, £12/£8, www.rigb.org

ASTEROID HIT OVER, nuclear war done, astrobiologist Lewis Dartnell


reveals how survivors could kick-start civilisation once more.

EDITOR'S
19 MAY CHOICE
3-8 JUNE
Does Learning Maths Change The Way We Think? Cheltenham Science Festival
Royal Society, London, 6.30pm, free, royalsociety.org
Cheltenham Town Hall and Imperial Gardens; for advance tickets call
DOES STUDYING MATHS develop generic ‘thinking skills’ that are 0844 880 8094 or visit cheltenhamfestivals.com/science
useful for life in general? Find out at this talk with Dr Matthew Inglis.
PROMISING TO BE yet another brain-bamboozling
festival, get inspired by scientists, thinkers, comedians
28 MAY and writers at thought-provoking talks and debates. Here are
just a few selected highlights…
How To Think Like A Freak
Royal Geographical Society, London, 7pm, intelligencesquared.com
Richard Dawkins: An Appetite For Wonder
IN THEIR BEST-SELLERS Freakonomics and SuperFreakonomics,
EVOLUTIONARY BIOLOGIST AND staunch atheist Dawkins
Steven D Levitt and Stephen J Dubner used data to challenge
became world famous for writing The God Delusion.
conventional wisdom. In this talk, they discuss their latest book.
Comedian and Radio 4 The Infinite Monkey Cage presenter
Robin Ince chats to the scientist about his life and works.
UNTIL 3 AUGUST

Open For Business Is Intelligence Heritable?


MOSI, Manchester, free, www.mosi.org.uk NATURE VERSUS NURTURE is an age-old debate. Renowned
scientist and TV presenter Lord Robert Winston talks to Prof
FROM WIG MAKING to graphene creation, this photographic exhibition Robert Plomin about his recent research into whether exam
takes you behind closed doors at factories and research institutes. results are more influenced by genetics or teaching.

UNTIL 7 SEPTEMBER How Will Our Footballers Cope In The Amazon?


Mammoths: Ice Age Giants SILKY SKILLS ON a cold, windy pitch in Manchester don’t
necessarily translate to success in the humid heat of Brazil.
Natural History Museum, London, £10/£6, Prof Alice Roberts, Dr Kevin Fong (both pictured) and Greg
www.nhm.ac.uk/mammoths
Whyte investigate whether our players will be able to cut it in
LIVE LIFE AS a woolly mammoth for a day, discover vast fossils and this year’s World Cup finals.
life-size models, and try your hand at tusk jousting!

UNTIL 30 NOVEMBER UNTIL 18 DECEMBER

Ancient Lives: New Discoveries Being Caroline


British Museum, London, £10, www.britishmuseum.org Herschel Museum, Bath, free, herschelmuseum.org.uk

ORDINARY ANCIENT EGYPTIANS were much like us, with bad diets, DISFIGURED BY SMALLPOX as a child, Caroline Herschel battled
toothache and tattoos. We know this thanks to CT scans of the societal norms to become one of the greatest astronomers of all
eight mummies in this exhibition, one of which is 5,500 years old. time. This exhibition reveals both her work and her personal life.

JUNE 2014 / FOCUS / 103


To Do List

READ
THE LATEST SCIENCE BOOKS REVIEWED Hardback Paperback

Do No Harm MEET THE AUTHOR


Stories Of Life, Death And
Brain Surgery EDITOR'S
CHOICE
Henry Marsh Henry
Weidenfeld & Nicolson £16.99
Marsh
Why did you write the book?

T
HIS IS A deeply compassionate
account of a professional life There’s a great myth about brain surgery
spent on the edge, a job which that it’s terribly di�cult – actually it’s not
has huge highs and appalling lows. if you know what you’re doing. But it is
As Henry Marsh writes in the preface: di�cult in the sense that it’s very
“A brain surgeon’s life is never boring dangerous and the problems it presents
and can be profoundly rewarding, but to both surgeon and patient are very
it comes at a price. You will inevitably real. I wanted to write about that. Another
make mistakes and you must learn to live reason for writing the book is that,
with the occasionally awful consequences.” although life as a brain surgeon is often
A few years ago I made a television harrowing, it is also often very wonderful.
series on the history of surgery, which As I’ve got older I’ve been filled with an
included a programme about neurosurgery. increasing sense of awe at the fact that
It began with me chatting to a young description of an operation to remove an everything we think and feel is the
woman lying on an operating table while aneurysm – a weakened artery – from deep electrochemical chatter of our brain cells.
a neurosurgeon removed a tumour from within the brain of a 32-year-old woman.
her brain. They had to operate while He thinks an operation is too dangerous, Is it nerve-racking to cut into
she was fully conscious to reduce the risk but she wants it removed. Towards the end someone’s brain?
that, along with the tumour, the surgeon of the operation, when he is ready to clip When operating, you know that if you
would accidentally remove normal, healthy the artery, the instrument he’s using to do cause damage you’ll have a damaged
brain tissue. so fails. It is a heart-stopping moment. patient at the end, so you’re always
This is the dilemma that all neurosurgeons Henry Marsh knows that he has to do anxious. It’s exciting, but it’s never
face. They are operating on a part of the something, but he doesn’t know what: “I exhilarating until the patient’s woken up
body (if you can describe the brain that cannot move my hand for fear of tearing and is all right. I remember once being in
way) where there is no scope for error; the minute, fragile aneurysm… and causing a casino watching people gambling, and
where even the slightest mistake can have a catastrophic haemorrhage. I sit there the absolute intensity with which they
profound repercussions. The human brain motionless, with my hand frozen in space.” watched that roulette ball reminds me of
is unbelievably complex, but that also He knows that the slightest mistake the intensity you have when operating.
makes it extremely vulnerable. will lead to this young, healthy woman
Henry Marsh is a world-class su�ering a major stroke and permanent Are some operations more
neurosurgeon but he is also a great brain damage. He has to act but how? The challenging than others?
storyteller. Take, for example, his situation is unbearably tense, and makes They’re all dangerous, but there are
for a page-turner. degrees of danger. Technically, the most
Fortunately, in this case all ends well, di�cult are some of the big, slow-
“The slightest but how many of us would want to face growing benign tumours that grow
underneath the brain o� the skull. The
mistake will lead those dilemmas on a regular basis as part
of our daily lives? I once thought I would like operation that led me to become a
neurosurgeon was aneurysm surgery,
to this young, to be a neurosurgeon; now I am glad that I
took a di�erent path. where you’re dealing with blowouts on
healthy woman This is an extraordinary book by an blood vessels to the brain. It’s bomb
disposal work for cowards – the surgeon’s
extraordinary man.
suffering a QQQQQ life isn’t at risk, but the patient’s is.

major stroke” DR MICHAEL MOSLEY is a journalist and


MORE ON THE PODCAST
Listen to the full interview with Henry Marsh
at sciencefocus.com/podcasts
presenter who returns to BBC TV in
Trust Me I’m A Doctor, coming soon

104 / FOCUS / JUNE 2014


To Do List

The Extreme Life Of The Sea Inheritance Island On Fire


Stephen R Palumbi and Anthony R Palumbi How Our Genes Change Our Lives And Our The Extraordinary Story Of Laki, The Volcano
Princeton University Press £19.95 Lives Change Our Genes That Turned Eighteenth-Century Europe Dark
Sharon Moalem Alexandra Witze and Je� Kanipe
ONE OF THE snags of ‘accessible’ science Sceptre £18.99 Profile Books £12.99
books is that they can be anything but.
The dazzling intellect of Dawkins and IF YOU WERE to raise a chimpanzee as a THE LAST TIME clouds of ash from an
Gould can intimidate even when stripped human you would still get a chimpanzee, Icelandic eruption paid us a visit, the
down for mere mortals like us, so it was and this tells us that the genes we inherit result was mayhem: the cancellation of
with some trepidation that I opened The from our parents really do matter. But more than 100,000 flights wrecking the
Extreme Life Of The Sea. the scientific study of epigenetics is travel plans of 10 million people. It could,
Such reservations were swiftly showing that our genetic destiny is not however, have been far worse. In 1783, a
quashed. It’s a book full of big, juicy, fixed at conception: how we are brought vast outpouring of lava from the island’s
well-I-never facts, written in a highly up, what we eat or even how our parents Laki volcano loaded the atmosphere
entertaining style that will appeal to all. were brought up and what they ate, can with noxious sulphur gases, which the
Did you know that swordfish heat their a�ect our genes. Rats fed spinach are weather then launched towards Europe.
eyeballs to improve their vision? Me resistant to some cancers, because As the authors observe in this
neither. That such a thing as an immortal compounds in the spinach modify genes fascinating account of the blast, the
jellyfish exists? And - my personal that help to fight these cancers. Female result was a smog-ridden summer,
favourite - that certain viruses infect mice given vitamins can benefit their swiftly followed by a bitter winter, as the
winkles specifically so they commit o�spring by modifying their genes to gaseous shroud blocked out the Sun.
suicide by losing their fear of heights? make them less susceptible to diabetes. One-fifth of Iceland’s inhabitants died
This is a terrific book, a celebration Sharon Moalem’s breezy Inheritance during the resulting famine, while across
of the extraordinary adaptations of recounts the latest in a rapidly growing Europe, the young, old and infirm
marine life, a eulogy to the complexity of list of ways that environmental factors succumbed to the smog and weather;
the ecosystems of the sea, as well as a can alter genes, and how those alterations around 20,000 extra deaths occurred in
lament about the potential fate that awaits can influence health. We don’t yet know England alone. Signs of this cull may be
the oceans if man’s destructive activities how these e�ects will translate to humans, gleaned by a visit to a graveyard. I went
continue unfettered. but the era of the designer gene is being over to one nearby and the first two
It’s a book for anyone who has peered ushered in, and insurance companies and gravestones I encountered both recorded
into a rock pool and marvelled at its your doctor will want to get in on the act. deaths in late 1783. Coincidence?
contents, and a perfect gateway - open You can stay one step ahead by reading Probably, but as the authors warn, the
to all - into the wonderful world of Moalem’s account of this fascinating, and impact of the next Icelandic blast may
marine science. sometimes alarming, new field. ruin far more than a few package holidays.
QQQQQ QQQQQ QQQQQ

MONTY HALLS is a marine biologist and MARK PAGEL is head of the Evolutionary GILES SPARROW is a science writer
BBC TV presenter Biology Group at the University of Reading and the author of Physics In Minutes

IT IS 55 years since the great American take us through the importance of self
physicist Richard Feynman speculated assembly, learning from nature’s ability
on the potential to build objects a few to make complex structures from simple
atoms across. Since then, it might seem instructions, then go on to discuss graphene
that nanotechnology has gone nowhere. and the possibilities for nanomedicine.
We’ve heard more about fictional nanobots However, the images, while striking, are
rebelling as all-consuming ‘grey goo’ than poorly laid out and the flow of a good
wondrous new tech. But Nanoscience popular science book is missing. Instead
demonstrates that there have been many you are bombarded with facts and artistic
remarkable developments. interpretations. Nanoscience has great
Nanoscience The early prophets of nanotechnology
assumed it would involve tiny but traditional
content, but is let down by the presentation.
QQQQQ
Giants Of The Infinitesimal feats of engineering. However, on the
Peter Forbes and Tom Grimsey scale of cells and large molecules, BRIAN CLEGG is the author of Dice World:
Papadakis £24.99 di�erent forces apply. Forbes and Grimsey Science And Life In A Random Universe

JUNE 2014 / FOCUS / 105


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Mindgames

MINDGAMES
Test your knowledge with our Big Quiz set by James Lloyd

Complete the recent headline: “Nose This Apollo 11 emblem, carried


Don’t miss Only Connect, a
brain-bending quiz hosted
by Victoria Coren on BBC
Four - see radiotimes.com for details

Which bird is the most regular visitor


1 can detect one ________ odours”? 5 10 to British gardens, according to this
aboard the spaceflight that landed
the first humans on the Moon, year’s Big Garden Birdwatch?
a) Million
recently fetched how much at
b) Billion a) House sparrow
auction?
c) Trillion b) Blue tit
a) $12,500 c) Starling
(£7,464)
According to recent research, b) $62,500
2 (£37,322)
why might the giant bluestones of According to research published
11
Stonehenge have been chosen? c) $112,500 in March, the planet Mercury has
(£67,180) shrunk by around how much over its
a) For the sound they make when struck
4.6-billion-year history?
b) For their ability to absorb the Sun’s
heat a) 3km
c) For the way they cleave when struck, b) 5km
making them easy to shape c) 7km
A McVitie’s-commissioned study
6
has found that which biscuit is best
for dunking?
The Cassini spacecraft has A recent study by University College
3 a) Rich tea 12 London researchers recommends
confirmed the existence of a
subsurface ocean on which b) Ginger nut eating how many portions of fruit
of Saturn’s moons? c) Malted milk and vegetables per day?
a) Titan a) Five
b) Enceladus b) Six
c) Mimas According to Canadian researchers, c) Seven
7
what’s one way that peacocks
attract females’ attention?

a) By offering their vomit as a present


4 How have scientists nicknamed the b) By making fake sex sounds 13 This adorable little critter was a
Anzu wyliei, a recently discovered recent arrival at Denver Zoo. What
dinosaur species? c) By moving their necks in a figure-of- kind of animal is it?
eight motion
a) The lizard with no gizzard a) Cheetah
b) The clawed cannibal b) Clouded leopard
c) The chicken from Hell c) Fishing cat
8 Complete the recent headline:
“Did ________ ________ help kill off the
dinosaurs?”
PHOTO: BONHAMS, DENVER ZOO, CARNEGIE MUSEUM OF NATURAL HISTORY

a) Dark matter
b) Tiny arms
c) Poisoned ferns

9 What’s the name of the project that


has detected the first gravitational
waves from the Big Bang?

a) DRICEP2
b) TRICEP2
c) BICEP2

The Anzu wyliei stood 3m (9.8ft) tall and had feathers Ahh - what a cute ________

JUNE 2014 / FOCUS / 111


Mindgames

1c, 2a, 3b, 4c, 5b, 6a, 7b, 8a, 9c, 10a, 11c, 12c, 13b
QUIZ ANSWERS
HOW DID YOU SCORE? 0-4 DOPEY DODO 5-9 PRETTY PARROT 10-13 PREENING PEACOCK

41 Removal includes certain cells (3)

FOCUS CROSSWORD No 164 ACROSS 42 Song about soldier returning to


personal connection (8)

10
Harold accepted stupid moron was
chemically affected (8)
Question a UN agency (3)
DOWN
11 A little bit in favour of weight (6) 1 Borrow name reinvented for connective
12 Crime is solved with time – it’s not tissue (4,6)
Imperial (6) 2 The ruler in the mirror (4)
13 Old ship’s kitchen appliance (7) 3 Article by a prisoner has attorney as a
14 Origin of a Wimbledon favourite (4) reptile (8)
15 Crank bison, wild in the forest, say (6,4) 4 Impressionable student in history in
17 Inuit mat made out of metal (8) charge (7)
18 I managed to get a Scotsman and an 5 Mention call about carbon, say (11)
Arab (7) 6 Mettle shown by the French politician
19 Superlatives about computer provides illumination (6,4)
language (4) 7 Pressure soon developed to include one
21 Feline knocks top off part of flower (6) toxin (6)
24 Wren set off with half a mind to see 8 Spy solved clue in part of compound (8)
part of the world (7,10) 10 Wife and husband had moose with
27 Romance a fellow finds reasonable (6) seafood (5)
29 Former spouse takes morning test (4) 16 Ridge is returning to a plant (7)
30 Usual problem getting married to new 20 Point out mean, intrusive procedure (5)
graduate (7) 22 At last, recluse finds welding gear (7)
33 Entertainer to deceive someone in 23 Combining a bit of calculus (11)
court (8) 25 Pure matter sent as aid (3,7)
35 Financial instrument is hardly original (10) 26 Match having the same set of solutions (10)
36 Part of the house that’s covered in 28 I will get a loft conversion started on
feathers (4) some ships (8)
37 Musicians’ group volunteers 31 Trainee always has time for influence (8
information that causes change (7) 32 Scrap new union in large upheaval (7)
38 Our leg cooked at a certain 34 A jug used by artist is tipped up by cat (6)
temperature (6 35 Follow mother’s blind faith (5)
40 Paraffin may talk a neighbour round (6) 39 Willing bird (4)

SOLUTION TO CROSSWORD No 161 YOUR DETAILS


Philip Cooper, Susan Wilton, Alan Pyatt, Graham NAME
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MUSEUM ALIVE
The first five correct solutions
drawn will each win a copy of
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112 / FOCUS / JUNE 2014


Artificial
intelligence in
TRANSCENDENCE
RECENTLY I SUFFERED the humiliation of
my six-year-old son having to show me
how to use our new smart TV. Technology
and, more annoyingly six-year-olds, are
becoming increasingly intelligent. It won’t
be long till my boy outwits me, but how long
before computers become cleverer than
humans, and what happens when they do?
I thought technology was becoming
sophisticated when I bought an intelligent
vacuum cleaner and it told me to stop living
like a slob. But it’s about to get a whole
lot smarter. In Wally Pfister’s latest film,
AI researcher Will Caster (Johnny Depp)
creates a computer with greater-than-
human intelligence by uploading himself
to it. Depp (cue dramatic music) calls it
Transcendence.
The idea, says AI researcher Stuart
Armstrong from Oxford University’s Future
of Humanity Institute, isn’t far-fetched.
In fact, scientists believe there will be a
point at which machines will become more
intelligent than humans, known as the
‘singularity’. Much like my six-year-old, and
in line with Moore’s law, computers are
doubling in power every two years - so the

“He creates a computer


with greater-than-
human intelligence”
hardware isn’t a problem. Generating the software to run it, however, is. manipulate the world economy; so skilled socially, it can manipulate and
One option, says Armstrong, is to upload a brain into a computer. Encoded win over human minds. It would rise inexorably to global power.
into processing language, it would be cheaper to run and more reliable I could live with that too, as long as it’s programmed to keep me safe. But
than its fallible biological counterpart. Complicated skills, like becoming a therein lies the rub. What’s to stop it from locking me in a bunker and putting
lawyer, could be learned in a fraction of the time. Added to that, the me into a coma to protect me from the world at large? Very little, apparently.
ILLUSTRATOR: TRACIE CHING

program could clone itself millions of times. Human lawyers will be “To be safe, an AI will need to be given an extremely precise definition of
heading to the job centre only to find the staff there have been replaced proper behaviour,” says Armstrong. “But that is very hard to do.”
by know-it-all automatons (not that they’d notice the difference). “At the Like it or not, Armstrong estimates that, barring a global catastrophe,
minimum, you’ve just unemployed everyone on the planet,” says Armstrong. ‘transcendence’ is inevitable, some time in the next five to 100 years. On
So far, so good; I could learn to love a life of leisure. But there’s reason to the plus side, I might finally end up with predictive text that actually works.
believe these computers will do more than take our jobs. “If AI becomes It’ll make my six-year-old
particularly powerful, you’d expect it to take control of the world, for better happier next time we go to HELEN PILCHER is a science writer and
or for worse,” says Armstrong. Imagine AI so powerful it can predict and visit Satan’s grotto. � comedian. She tweets from @helenpilcher1

114 / FOCUS / JUNE 2014


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