Strategic Health IT Advanced Research Projects (SHARP)

Research Focus Area: 4. Secondary Use of EHR Data - Project Charter

Project Title/Name: Data Normalization and Evaluation

Project Leads: Dr. Christopher Chute, Dr. Stan Huf
Project Manager Lacey Hart
Date: July 20, 2010 – December 2010
To be completed during Project Approval Process
Portfolio: Program: Project Number:
Mayo Clinic Research - BSI PMO SHARP Area 4 Projects 1 & 6

Brief Project Background & Description: (What will this project do?) (255 characters):
 Data liquidity requires transformation of non-standard patient data into comparable consistent formats
 In practice, clinical data and provider information is unstructured and non-standard
 Overall Aim: Develop an open-source, dynamically configurable services framework to transform health
information into standards-conforming, comparable, and consistent data

Objectives: (Problem or Opportunity Statement / Background of Project Need)

 Build generalizable data normalization pipeline
 Semantic normalization annotators involving LexEVS
 Establish a globally available resource for health terminologies and value sets
 Establish and expand modular library of normalization algorithms
 Consistent and standardized common model to support large-scale vocabulary use and adoption
 Support mapping into canonical value sets
 Normalize the data against CEMs.
 Normalize retrospective data from the EMRs and compare it to normalized data that already exists in our data
warehouses (Mayo Enterprise Data Trust, Intermountain).
 Iteratively test normalization pipelines, including NLP where appropriate, against normalized forms, and tabulate
discordance.
 Use cohort identification algorithms in both EMR data and EDW data.
 Sharing data through NHIN Connect and/or NHIN Direct
 Comparison of data processed through SHARP to data in existing Mayo and Intermountain data trust, EDW, AHR
 Evaluation of NLP outputs and value? Focus on a specific domain: X-rays, operative notes, progress notes, sleep studies?

Project Scope:
IN Scope OUT of Scope
List items/functionality to be accomplished here List all exclusions (out of scope) here
Use case evaluation for data element extraction Scientific use case validation
Data class identification/prioritization New information models
Generalizable data normalization pipeline Disease specific widgets?
Normalization annotators
standardized common model & mapping
Iteratively test normalization pipeline
NHIN connection

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 Strategic Health IT Advanced Research Projects (SHARP)
Research Focus Area: 4. Secondary Use of EHR Data - Project Charter

Preliminary Timeline: (Enter any applicable milestone or deliverable dates)

Milestone or Deliverable Target Completion Date
Charter Approved 7/27/2010
Identify Use Cases 7/27/2010
Seek Common data elements and classes of data 8/11/2010
Prioritize list of classes & desired widgets 8/18/2010
Evaluate normalization tools & models (i.e. Regenstrief) 9/1/2010
Define normalization templates (invoke CEMs, etc) 9/1/2010
PAD& T2D Widgets for HTP Team 10/2010
PE & PNA Widgets for HTP Team 12/2010
Define infrastructure information model framework TBD
Define role of normalized data in NHIN connect TBD

R o l e s a n d R e s p o n s i b i l i t i e s : (Enter the estimated resources needed to initiate the project)

Team Roles / Resource Skill Set Needed Name FTE needed
Lead Christopher Chute 5%
Lead Stan Huf 5%
PM Lacey Hart 5%
IT Arch Tom Johnson 5%
Phenotyping Jyoti Pathak
Cui Tao
Agilex Kyle Marchant
Agilex Les Westberg
MN HIE Mike Ubl
Peter Haug
Tom Oniki

D e p e n d e n c i e s / A s s u m p t i o n s / R i s k s / C o n s t r a i n t s : (Enter any known or anticipated points to

communicate)
 High dependency on NLP, HTP and Infrastructure project resources.
 Dependent upon IRB approval at both Utah and Mayo

Terms:
• AHR: Analytic Health Repository
• CEM: Clinical Element Model
• Decision Support Related:
– CER: Comparative Efectiveness Research (cost excluded)
– HTA: Health Technology Assessment (cost benefit/efectiveness)
– QI: Quality Improvement (health care operations)
– CDS: Clinical Decision Support (bedside)
• ETL: Extract Transform Load

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 Strategic Health IT Advanced Research Projects (SHARP)
Research Focus Area: 4. Secondary Use of EHR Data - Project Charter

• NHIN: Nationwide Health Information Network

Endorsement:

Endorsed Not Endorsed Deferred until ______________________

Comments (Enter endorsement mechanism and any other comments)



Title Signature Date

__________________________ _________
Project Owner(s):

Project Manager: __________________________ __________

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