Angina | Precipitating Factors: 4 E’s ◾E1 | Exertion: physical activity and exercise ◾E2 | Eating ◾E3 | Emotional distress ◾E4 | Extreme temperatures: hot or cold weather Arterial Occlusion: 4 P’s ◾P1 | Pain ◾P2 | Pulselessness or absent pulse ◾P3 | Pallor ◾P4 | Paresthesia Blood Pressure Formula: BP = CO x SVR ◾Blood Pressure ◾Cardiac Output ◾Systemic Vascular Resistance Congestive Heart Failure Treatment: MADD DOG ◾M | Morphine ◾A | Aminophylline ◾D | Digoxin ◾D | Dopamine ◾D | Diuretics ◾O | Oxygen ◾G | Gasses (Arterial blood gasses [ABGs] monitoring) Cor Pulmonale Signs and Symptoms: Please Read His Text ◾P | Peripheral edema ◾R | Raised JVP ◾H | Hepatomegaly ◾T | Tricuspid incompetence Coronary Arteries Location: Right CAMP Left ARC (I have a Right to CAMP if you Left an ARC) ◾Right = Right ◾Coronary ◾Artery ◾Marginal Artery ◾Posterior Interventricular Artery ◾Left = Left ◾Anterior Interventricular Artery ◾Circumflex Artery Endocarditis: FAME ◾Fever ◾Anemia ◾Murmur = think Endocarditis Heart Murmur Causes: SPAMS ◾S | Stenosis of a valve ◾P | Partial obstruction ◾A | Aneurysms ◾M | Mitral regurgitation ◾S | Septal defect Heart Sounds: All People Enjoy the Mall ◾A | Aortic: 2nd right intercostal space ◾P | Pulmonic: 2nd left intercostal space ◾E | Erb’s Point: 3rd left intercostal space ◾T | Tricuspid: 4th left intercostal space ◾M | Mitral or Apex: 5th left intercostal space Hypertension Care: DIURETIC ◾D | Daily weight ◾I | I/Os ◾U | Urine output* ◾R | Response of blood pressure ◾E | Electrolytes ◾T | Take pulse (tachycardia may occur in response to hypotension) ◾I | Ischemic episodes or TIAs ◾C | Complications: CVA, CAD, CHR, CRF *Note: Excessive urination may indicate that diuretics dose are too high and lead to dehydration. Decreased urine output may be associated with impaired renal function. Declined renal function is often the first non-cardiac sign of a cardiac issue. Myocardial Infarction Nursing Management: BOOMAR ◾B | Bed rest ◾O | Oxygen therapy ◾O | Opioids: morphine ◾M | Monitoring: vitals, arterial blood gases, cardiac enzymes, and other blood work ◾A | Anticoagulation therapy ◾R | Reduce clot size Myocardial Infarction Treatment: MONA (or ON AM for the correct order)* ◾M | Morphine ◾O | Oxygen ◾N | Nitroglycerin ◾A | Aspirin *The correct order of MONA interventions is oxygen, nitroglycerin, aspirin, and then morphine. This can be remembered by the mnemonic: ON AM (I am ON fire in the AM as I am a morning person) Shortness of Breath (SOB) Causes: AAAAPPPP ◾A | Airway obstruction ◾A | Angina ◾A | Anxiety ◾A | Asthma ◾P | Pneumonia ◾P | Pneumothorax ◾P | Pulmonary Edema ◾P | Pulmonary Embolus Heparin-Induced Thrombocytopenia (HIT) Probability: The 4 T’s* 1. T | Thrombocytopenia present (low platelet count): >50% fall in platelet levels = Higher probability of it being HIT 2.T | Timing of platelet count fall: Drop occurs during the 5-10 days after heparin use (most common time period for reaction to occur) or drop occurs rapidly (less than 1 day) and heparin exposure occurred within past 30 days = Higher probability of it being HIT 3.T | Thrombosis or other sequelae. Proven thrombosis or presence of skin necrosis, or an acute systemic reaction following administration of a heparin bolus = Higher probability of it being HIT 4.T | Thrombocytopenia, other causes. No other evident = Higher probability of it being HIT *Thrombocytopenia is a low platelet level. There are various etiologies that may be responsible, but one cause is heparin-induced (AKA: HIT), which is an immune mediated reaction following drug exposure. The 4 T’s is used to predict the probability that the thrombocytopenia is associated with heparin use. Tetralogy of Fallot: PROVe ◾P: Pulmonary stenosis (narrowed pulmonary artery) ◾R: Right ventricular hypertrophy (enlarged right ventricle) ◾O: Overriding aorta (malposition of the aorta over both ventricles) ◾V: Ventricular septal defect ◾e* *The lowercase “e” is intentionally left blank as its purpose it to serve as a filler for the mnemonic Ventricular Arrhythmias Drugs: AL ◾A | Amiodorone ◾L | Lidocaine Critical Care Critical Care Acronyms and Mnemonics Advanced Life Support Drugs: LEAN ◾L | Lidocaine ◾E | Epinephrine ◾A | Atropine ◾N | Narcan Compartment Syndrome Signs and Symptoms: 5 P’s 1.P | Pain 2.P | Pallor 3.P | Pulse declined or absent 4.P | Pressure increased 5.P | Paresthesia Emergent Syncope: CRAPS (Like the Vegas Gambling Game) ◾C | Cardiac ◾R | Ruptured AAA (abdominal aortic aneurysm, AKA: “Triple A”) ◾A | Aortic stenosis ◾P | Pulmonary embolism (PE) ◾S | Subarachnoid hemorrhage Shock Characteristics: HYPO-TACHY-TACHY ◾Hypotension ◾Tachycardia (elevated heart rate of 100 bpm or > at rest* in adults) ◾Tachypnea (elevated respiration rate) The Significance of Tachycardia | Tachycardia is an anticipated finding in an individual who is exerting his or herself; for example, the heart rate can easily reach 160 while working out on cardio equipment at the gym. In a clinical setting, tachycardia is typically used to reference an individual with an elevated pulse while at rest, or not exerting his or herself physically. Shock Signs and Symptoms: CHORD ITEM ◾C | Cold, clammy skin ◾H | Hypotension ◾O | Oliguria ◾R | Rapid, shallow breathing ◾D | Drowsiness, confusion ◾I | Irritability ◾T | Tachycardia ◾E | Elevated or reduced central venous pressure ◾M | Multi-organ damage Shock Differential: CHORD ◾C | Cardiac ◾H | Hypovolemia ◾O | Obstructive (tension pneumothorax, tamponade, PE) ◾R | Respiratory/medical (hypoxia, acidosis, hypothermia, hyperkalemia, OD) ◾D | Distributive (spinal shock, anaphylaxis, sepsis) Shock Types: SHRIMP CAN ◾S | Septic ◾H | Hemorrhagic ◾R | Respiratory ◾I | Insulin- hypoglycemia from insulin overdose or extreme hyperglycemia – diabetic ketoacidosis (DKA) ◾M | Metabolic ◾P | Psychogenic ◾C | Cardiogenic ◾A | Anaphylactic ◾N | Neurogenic Shock Types: RN CHAMPS ◾R | Respiratory ◾N | Neurogenic ◾C | Cardiogenic ◾H | Hemorrhagic ◾A | Anaphylactic ◾M | Metabolic ◾P | Psychogenic ◾S | Septic Diabetes Diabetes Acronyms and Mnemonics Diabetic Ketoacidosis (DKA) Treatment: KING UFC ◾K | K+ (potassium) ◾I | Insulin ◾N | Nasogastric tube: if the patient is comatose ◾G | Glucose: once serum levels drop ◾U | Urea: monitoring ◾F | Fluids: crystalloids ◾C | Creatinine: monitor and catheterize Exercise Regimen for Patients with Diabetes: FIT ◾F | Frequency: 3 times a week ◾I | Intervals: 30 minutes a day ◾T | Time Hyperglycemia Versus Hypoglycemia ◾HYPER | Hot N’ dry: Sugar high ◾HYPO | Cold N’ clammy: Need some candy Hypoglycemia Causes and Characteristics: RE-EXPLAIN ◾RE | REnal failure ◾EX | EXogenous ◾P | Pituitary ◾L | Liver failure ◾A | Alcohol ◾I | Infection ◾N | Neoplasm Hypoglycemia Signs: TIRED ◾T | Tachycardia ◾I | Irritability ◾R | Restlessness ◾E | Excessive hunger ◾D | Depression and diaphoresis Mixing 2 Types of Insulin in 1 Syringe: Clear, Cloudy, Cloudy, Clear ◾Clear before cloudy ◾Cloudy before clear Diagnostics/Labs Diagnostic and Lab Value Acronyms and Mnemonics Acid Base: ROME ◾R | Respiratory (acidosis and alkalosis) ◾O | Opposite: pH ↓ & CO2 ↑ = Acidosis; pH ↑ CO2 ↓= Alkalosis ◾M | Metabolic (acidosis and alkalosis) ◾E | Equal: pH ↓ & HCO3 ↓ = Acidosis; pH ↑ & HCO3 ↑= Alkalosis Calcium: 8.5-10 ◾Children’s bones grow strong between ages 8 ½ -10 ◾This is a way to remember the range of normal calcium values in the blood serum CBC (Complete Blood Count) Components: HELPR ◾H | H/H (Hemoglobin/Hematocrit) ◾E | Erythrocytes (RBCs) ◾L | Leukocytes (WBCs) ◾P | Platelets ◾R | R/R* (reticulocytes/RBC indices)# *Unlike H/H (which stands for hemoglobin/hematocrit), R/R is NOT a term typically used to describe reticulocytes/RBC indices…it’s just used for the purpose of this mnemonic. #RBC indices involve components that are used to describe the shape, size, and other characteristics of the RBCs…They’re important for differentiating the type of anemia. Potassium: 3.5 -5 POTS ◾Children age 3½ -5 like to play with POTS (example: making mud pies) ◾This is a way to remember the normal range of potassium values Lab Values from Lowest to Highest: Miss Piggy & Kermit Came Home on Cloud Nine ◾Miss: Magnesium = 1.5-2.5 ◾Piggy: Phosphate = 2.5-4.5 ◾& ◾Kermit: (K) Potassium = 3.5-5.5 ◾Came: Calcium = 8.5-10.5 ◾Home: HCO2 = 22-26 ◾On: Oxygen Saturation = 95-100% ◾Cloud: Chloride = 95-104 ◾Nine: (Na) Sodium = 135-145 Electrolytes Electrolytes Acronyms and Mnemonics Hypernatremia Signs and Symptoms: FRIED SALT ◾F | Flush skin and fever (low-grade) ◾R | Restless, irritable, anxious, confused ◾I | Increased blood pressure and fluid retention ◾E | Edema: peripheral and pitting ◾D | Decreased urine output and dry mouth ◾S | Skin flushed ◾A | Agitation ◾L | Low-grade fever ◾T | Thirst Hypernatremia Causes: MODEL ◾M | Meals (high intake) and medications ◾O | Osmotic diuresis ◾D | Diabetes Insipidus ◾E | Excessive loss of water ◾L | Low intake of water Hypocalcaemia Signs and Symptoms: CATS ◾C | Convulsions ◾A | Arrhythmias ◾T | Tetany ◾A | Stridor and spasms Hyperkalemia (High K+) Causes: MACHINE ◾M | Meds: ACE inhibitors, NSAIDS, Diuretics (potassium sparing) ◾A | Acidosis: Metabolic and respiratory ◾C | Cellular destruction: Burns, traumatic injury ◾H | Hypoaldosteronism and hemolysis ◾I | Intake: Excessive dietary consumption (eg: Salt replacements products that contain potassium) ◾N | Nephrons: Renal failure ◾E | Excretion: Impaired (unable to excrete K+ normally) Hyperkalemia Signs and Symptoms: MURDER ◾M | Muscle cramps that progress to weakness or even paralysis ◾U | Urine abnormalities: Oliguria or anuria (output less than 30 mL/hour or no output) ◾R | Respiratory distress ◾D | Decreased cardiac contractility ◾E | EKG changes ◾R | Reflexes: Hyperreflexia or areflexia (flaccidity) Hyperkalemia Treatment: C BIG K DROP ◾C | Calcium ◾B | Bicarbonate ◾I | Insulin ◾G | Glucose ◾K | Kayexalate ◾D | Diuretics and dialysis Hypokalemia Signs and Symptoms: A SIC WALT ◾A | Alkalosis ◾S | Shallow Respirations ◾I | Irritability ◾C | Confusion and drowsiness ◾W | Weakness and fatigue ◾A | Arrhythmias: tachycardia or bradycardia, irregular rhythm ◾L | Lethargy ◾T | Thready Pulse ◾(Other signs: decreased intestinal mobility, vomiting, and ileus) Hypokalemia Causes and Characteristics: SUCTION ◾S | Skeletal muscle weakness ◾U | U-wave on EKG ◾C | Constipation ◾T | Toxicity to digoxin ◾I | Irregular and weak pulse ◾O | Otostasis ◾N | Numbness paresthesia Hypokalemia Signs and Symptoms: 6 L’s ◾L | Lethargy ◾L | Leg cramps ◾L | Limp muscles ◾L | Low, shallow respirations ◾L | Lethal cardiac dysrhythmias ◾L | Lots of urine (polyuria) Endocrine Endocrine System Acronyms and Mnemonics Adrenal Hormones: SSS | Salt, Sugar, Sex ◾S | Sugar: Glucocorticoids = Glucose control, stress and immunity (Memory Trick: When you’re stressed, you eat too much sugar and you get sick) ◾S | Salt: Mineralocorticoids = Fluid/electrolyte balance and blood pressure regulation (Memory Trick: You drink mineral water in order to stay hydrated and keep your electrolytes and blood pressure balanced) ◾S | Sex: Androgens (testosterone and estrogen) = Sex drive/development (Memory Trick: Androgen + Estrogen = Drives sex, which is how humans are developed) Acute Pancreatitis Etiology: GET SMASH’D ◾G | Gallstones ◾E | Ethanol ◾T | Trauma ◾S | Steroids ◾M | Mumps ◾A | Autoimmune (PAN) ◾A | Scorpion bites ◾H | Hyperlipidemia ◾D | Drugs… such as azathioprine and diuretics Cushing’s Disease (Symptoms/Etiology/Patho): CUSHING ◾C: Central obesity and moon face ◾U: Urinary levels of free cortisol and glucose increased ◾S: Suppressed immunity, skin changes (skin thin, striae) ◾H: Hypercortisolism, hyperglycemia, hypercholesterolemia, hypernatremia, hypertension, hirsutism ◾I: Infections. Iatrogenic cause = Excessive use of corticosteroids ◾N: Non-iatrogenic cause = Neoplasms (benign pituitary or adrenal tumor that secretes cortisol) ◾G: Gynecomastia, glucose intolerance, growth delay, growth of hair Cushing’s Disease Signs/Symptoms: CUSHING ◾C: Central obesity/moon face ◾U: Urine high in cortisol and glucose ◾S: Skin changes ◾H: Hyperglycemia, hypernatremia, hypertension, hirsutism ◾I: Infections ◾N: Neoplasm observed in MRI (on the adrenal or pituitary gland) ◾G: Gynecomastia Antifibrinolytics Antifibrinolytics are used in menorrhagia and bleeding tendency due to various causes. Their application may be beneficial in patients with hyperfibrinolysis because they arrest bleeding rapidly if the other components of the haemostatic system are not severely affected. This may help to avoid the use of blood products such as fresh frozen plasma (FFP) with its associated risks of infections or anaphylactic reactions. These drugs block the binding sites of the enzymes or plasminogen respectively and thus stop plasmin formation. Warfarin Sodium (Coumadin) Coumadin is a prescription medicine used to treat blood clots and to lower the chance of blood clots forming in your body. Blood clots can cause a stroke, heart attack, or other serious conditions if they form in the legs or lungs. To help warfarin (Coumadin) work effectively, it is important to keep your vitamin K intake as consistent as possible. Sudden increases in vitamin K intake may decrease the effect of warfarin (Coumadin). On the other hand, greatly lowering your vitamin K intake could increase the effect of warfarin (Coumadin). Heparin Heparin is an anticoagulant (blood thinner) that prevents the formation of blood clots. Heparin is used to treat and prevent blood clots in the veins, arteries, or lung. Heparin is also used before surgery to reduce the risk of blood clots. Heparin – Coumadin (Responding Lab Tests) Partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) are used to test for the same functions; however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range. The aPTT is considered a more sensitive version of the PTT and is used to monitor the patient’s response to heparin therapy. The reference range of the aPTT is 30-40 seconds. The reference range of the PTT is 60-70 seconds. Critical values that should prompt a clinical alert are as follows: aPTT: More than 70 seconds (signifies spontaneous bleeding) PTT: More than 100 seconds (signifies spontaneous bleeding) Albumin Albumin helps move many small molecules through the blood, including bilirubin, calcium, progesterone, and medications. It plays an important role in keeping the fluid from the blood from leaking out into the tissues. Albumin is used in the treatment of shock, burns or low blood protein to temporarily correct or prevent a blood volume deficiency. Iron Supplements Iron supplements are dietary supplements containing iron that can be prescribed by a doctor for a medical reason, or purchased from a vitamin shop, drug store etc. They are primarily used to treat anemia or other iron deficiencies. The patient may notice that his/her stools become black. This is completely harmless, but patients must be warned about this to avoid unnecessary concern. When iron supplements are given in a liquid form, teeth may reversibly discolor (this can be avoided through the use of a straw). Intramuscular injection can be painful, and brown discoloration may be noticed. Clopidogrel (Plavix) Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). It works by blocking certain blood cells called platelets and prevents them from forming harmful blood clots. This “anti-platelet” effect helps keep blood flowing smoothly in your body. It might take longer than normal to stop bleeding if you cut yourself while taking clopidogrel. Epoetin Alfa (Procrit) Epoetin alfa injection is used to treat anemia (a lower than normal number of red blood cells) in people with chronic kidney failure (condition in which the kidneys slowly and permanently stop working over a period of time). Epoetin alfa injection is also used to treat anemia caused by chemotherapy in people with certain types of cancer or caused by zidovudine (AZT, Retrovir, in Trizivir, in Combivir), a medication used to treat human immunodeficiency virus (HIV). Epoetin alfa injection is also used before and after certain types of surgery to decrease the chance that blood transfusions (transfer of one person’s blood to another person’s body) will be needed because of blood loss during surgery. Epoetin alfa is in a class of medications called erythropoiesis-stimulating agents (ESAs). It works by causing the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells. Thrombolytics Thrombolytic medications are approved for the immediate treatment of stroke and heart attack. The most commonly used drug for thrombolytic therapy is tissue plasminogen activator (tPA), but other drugs can do the same thing. Thrombolytics work by dissolving a major clot quickly. This helps restart blood flow to the heart and helps prevent damage to the heart muscle. Thrombolytics can stop a heart attack that would otherwise be deadly. ACE Inhibitors Angiotensin-converting enzyme (ACE) inhibitors help relax blood vessels. ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance in your body that affects your cardiovascular system by narrowing your blood vessels and releasing hormones that can raise your blood pressure. This narrowing can cause high blood pressure and force your heart to work harder. ACE inhibitors are used for controlling high blood pressure, treating heart failure, preventing strokes, and preventing kidney damage in people with hypertension or diabetes. They also improve survival after heart attacks. ACE Inhibitors 2 ACE inhibitors are used to treat heart disease. These medicines make your heart work less hard by lowering your blood pressure. This keeps some kinds of heart disease from getting worse. Most people who have heart failure take these medicines. They also are used to treat diabetes and kidney problems. This can help keep your kidneys from getting worse. Adrenergic Antagonists (Alpha-Blockers) Alpha-blockers are medicines that are mainly used to treat hypertension (high blood pressure), and problems with passing urine in men who have enlargement of the prostate gland. If you have hypertension – alpha-blockers are usually prescribed after most other medicines have been tried. If you have problems passing urine (because of an enlarged prostate), the decision to start alpha-blockers depends on how much you are bothered by the symptoms. Side-effects are uncommon (slight drowsiness, headaches, and dizziness). They are more likely to occur in the first two weeks of treatment, and usually go away on their own. Although side-effects are uncommon, they occur in some people. Side-effects are more likely to occur in the first two weeks of treatment, and usually go away on their own. The most common side-effects are slight drowsiness, headaches and dizziness. If you are prescribed an alpha-blocker, read the leaflet that comes with the medicine packet for a full list of possible side-effects and cautions. Adrenergic Antagonists (Beta-Blockers) Beta-blockers are medicines that are used to treat various conditions including angina, high blood pressure, some abnormal heart rhythms, heart failure, myocardial infarction (heart attack), anxiety, overactive thyroid symptoms, glaucoma and migraine. Most people who take beta-blockers have no side-effects, or only minor ones. However, because of their action in various parts of the body, some people have unwanted side- effects such as the heart rate can go too slowly, Tiredness, depression, impotence. Antiarrhythmics Antiarrhythmic agents are pharmaceuticals used to combat cardiac arrhythmias. An arrhythmia is an abnormality of the rate or rhythm of the heartbeat, such as atrial fibrillation, atrial flutter, ventricular fibrillation and ventricular tachycardia. These drugs only control abnormal heart rhythms, not cure them. Antihypertensives Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Although beta blockers lower blood pressure, they do not have a positive benefit on endpoints as some other antihypertensives. Antihypertensives 2 There are many classes of antihypertensives, which lower blood pressure by different means; among the most important and most widely used are the thiazide diuretics, the ACE inhibitors, the calcium channel blockers, the beta blockers, and the angiotensin II receptor antagonists or ARBs. Among the most important and most widely used antihypertensive drugs are the thiazide diuretics, the ACE inhibitors, the calcium channel blockers, the beta blockers, and the angiotensin II receptor antagonists or ARBs. Beta-1 and Beta-2 Blockers When referring to beta 1 and beta 2 blockers, It is not the blockers that are 1 and 2, but the receptors they are blocking. There are actually three types of beta receptors. Beta 1 receptors are found in the heart and brain. Beta 2 receptors are found in the gastrointestinal tract, uterus, vascular smooth muscles, lungs, and skeletal muscles. Beta 3 receptors are found in fat cells. Cardioselective beta blockers (beta1- selective blockers) have a clinical advantage in that they mainly affect the heart, which predominantly has beta1 receptors. The effect of broncho-constriction is less with beta1 selective blockers, as the bronchial muscle has more beta2 receptors, however the danger of broncho-constriction cannot be totally ignored, as they are not totally selective. Beta Blockers Beta blockers, also known as beta-adrenergic blocking agents, are a class of drugs that works by blocking the neurotransmitters norepinephrine and epinephrine from binding to receptors. There are three known types of beta receptors, known as beta 1 (β1), beta2 (β2) and beta3 (β3). When the neurotransmitters are prevented from binding to the receptors, it in turn causes the effects of adrenaline (epinephrine) to be blocked. This action allows the heart to relax and beat more slowly thereby reducing the amount of blood that the heart must pump. Over time, this action improves the pumping mechanism of the heart. Calcium Antagonists Calcium antagonist-based regimen is superior to other regimens in preventing stroke, equivalent in preventing ischemic heart disease, and inferior in preventing congestive heart failure. Calcium antagonists are also safe and effective as first-line or add-on therapy in diabetic hypertensive patients. Heart rate-lowering calcium antagonists (verapamil, diltiazem) may have an edge over the dihydropyridines in post-myocardial infarction patients and in diabetic nephropathy. Thus, calcium antagonists may be safely used in the management of hypertension and angina pectoris. In several comparative studies in hypertensive patients, treatment with calcium antagonists was equally effective as treatment with diuretics, beta-blockers, or angiotensin-converting enzyme inhibitors. Cordarone (Amiodarone) Amiodarone belongs to the family of medications known as antiarrhythmics. It is used to treat certain types of abnormal heart rhythms (arrhythmias). It works by changing how electrical impulses affect the heart muscle and by making the heart beat more regularly. The effects of this medication may be noted as early as 3 days after starting treatment, but it is usually 1 to 3 weeks before beneficial effects are seen. Digitalis Digitalis medication works directly on the heart muscle to strengthen and regulate the heartbeat. It is used to treat certain heart conditions. Diarrhea, loss of appetite, drowsiness, headache, muscle weakness, and fatigue may occur as the body adjusts to the medication. Drugs for Bradycardia and Low Blood Pressure Use IDEA to treat bradycardia and hypotension. I – Isoproterenol, D – Dopamine, E – Epinephrine, A – Atropine Emergency Drugs Remember LEAN for emergency drugs. L – Lidocaine, E – Epinephrine, A – Atropine, N – Narcan Lidocaine Toxicity Overdosage with lidocaine can be a result of excessive administration via topical or parenteral routes, accidental oral ingestion of topical preparations by children, accidental intravenous (rather than subcutaneous, intrathecal or paracervical) injection or prolonged use of subcutaneous infiltration anesthesia during cosmetic surgical procedures. These occurrences have often led to severe toxicity or death in both children and adults. Lidocaine easily crosses from the blood to the brain, so, if an overdose has occurred, the following symptoms will probably show up first: headache, tinnitus (ringing in the ears), facial twitches, lightheadedness, a metallic taste, and numbness of the lips and tongue. In higher doses, there may also be seizures, unconsciousness, apnea, and CV collapse. At the highest doses, heart failure occurs. Focinopril (Monopril) Fosinopril is an angiotensin converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphinate-containing ACE inhibitor marketed. It is marketed by Bristol-Myers Squibb under the trade name Monopril. Monopril works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently. Nitroglycerin Nitroglycerin spray and tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). The spray and tablets may also be taken just before activities that may cause episodes of angina in order to prevent the angina from occurring. Nitroglycerin extended-release (long-acting) capsules are used to prevent episodes of angina in people who have coronary artery disease. The extended-release capsules can only be used to prevent angina attacks; they cannot be used to treat an attack once it has begun. Nitroglycerin is in a class of medications called vasodilators. Nitroglycerin works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Spironolactone (Aldactone) Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. This medication is also used to treat or prevent hypokalemia (low potassium levels in the blood). Bumetanide Bumex Bumetanide is a potent diuretic (water pill) that causes a profound increase in urine output (diuresis) by preventing the kidney from retaining fluid. Specifically, it blocks the reabsorption of sodium and fluid from the kidney’s tubules. It is in a class of diuretics called “loop” diuretics which also includes furosemide (Lasix) and torsemide (Demadex). Bumetanide is a very potent medication. Using too much of this drug can lead to serious water and salt/mineral loss. http://www.katzcriticalminds.com/uploads/6/5/6/4/6564433/9516621_orig.jpg
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