Blood pressure control in patients with

hypertension: a retrospective cohort study.

Aydogan, Umit 1 ; Doganer, Yusuf C; Atik, Asl; Rohrer, James E; Engin Gok, Deniz; Cirpan, Ebru; Yilmaz,
Mahmut I; Saglam, Kenan 1 Department of Family Medicine, Gulhane Military Medical Faculty, Ankara,
Turkey. . Journal of evaluation in clinical practice 21.2 (April 2015): 313-319.

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ABSTRACT
RATIONALE, AIMS AND OBJECTIVES
Hypertension (HT) is prevalent in Turkey and even with pharmacological interventions HT control rates do not
meet guideline recommendations. We aimed to estimate the proportion of hypertensive patients who achieved
target blood pressure (BP) and seek to determine the predictors responsible for failure of to reach goals.

METHODS
We conducted a retrospective cohort study involving patients with HT. A total of 437 patients were identified with
a current diagnosis of HT at baseline. All available predictors for BP improvements were included in the
multivariate linear regression model.

RESULTS
Follow-up data on HT goal achievements was available for 276 (63.1%) participants. Only 18.1% of the patients at
the baseline visit, and 48.6% at the follow-up visit achieved the overall SBP/DBP targets specified by the JNC-8
guideline. Significant differences were determined by baseline and 1st visit measurements of mean SBP/DBP
levels (P <0.001, P <0.001, respectively). DM and baseline SBP were positively associated with SBP improvement ( 
= 8.410, P = 0.003;  = 0.692, P <0.001, respectively), whereas being prescribing more HT medications and being
older were negatively associated with improvement ( = -7.968, P = 0.005;  = -5.707, P = 0.037; respectively). DM,
baseline DBP and HT duration were positively associated with DBP improvement ( = 4.539, P = 0.012;  = 0.702, P 
<0.001;  = 0.023, P = 0.012; respectively), whereas additional HT medications and GFR values were negatively
associated with improvement ( = -5.682, P = 0.002;  = -0.098, P = 0.005; respectively).

CONCLUSIONS
Although the progress in achieving in BP targets was encouraging, only half of patients had reached the HT goals.
Adequate pharmacological approaches and comprehensive management strategies should be implemented in
hypertensive patients.

DETAILS

Journal classification: Index Medicus

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MeSH subject: Adult; Age Factors; Aged; Aged, 80 and over; Blood Pressure; Body Mass Index;
Cardiovascular Diseases -- epidemiology; Comorbidity; Diabetes Mellitus --
epidemiology; Drug Therapy, Combination; Female; Humans; Male; Middle Aged;
Renal Insufficiency, Chronic -- epidemiology; Retrospective Studies; Risk Factors;
Sex Factors; Smoking -- epidemiology; Turkey; Antihypertensive Agents -- therapeutic
use (major); Hypertension -- drug therapy (major)

Substance: Substance: Antihypertensive Agents; CAS: 0

Identifier (keyword): blood pressure targets, guidelines, hypertension, improvement

Correspondence author: Aydogan, Umit  

Publication title: Journal of evaluation in clinical practice

Journal abbreviation: J Eval Clin Pract

Volume: 21

Issue: 2

Pages: 313-319

Number of pages: 7

Publication year: 2015

eISSN: 1365-2753

Source type: Scholarly Journals

Peer reviewed: Yes

Format availability: Internet

Language of publication: English

Record type: Journal Article

Publication history :

   Accepted date: 13 Jan 2016

      Revised date: 26 Mar 2015

   First submitted date: 26 Mar 2015

DOI: http://dx.doi.org/10.1111/jep.12318

Update: 2017-02-17

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Medline document status: MEDLINE

Electronic publication date: 2015-02-06

PubMed ID: 25659424

ProQuest document ID: 1667351134

Document URL: https://search.proquest.com/docview/1667351134?accountid=48290

Last updated: 2017-02-23

Database: Biological Science Database

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 Bibliography
Citation style: APA 6th - American Psychological Association, 6th Edition

Aydogan, U., Doganer, Y. C., Atik, A., Rohrer, J. E., Engin Gok, D., Cirpan, E., . . . Saglam, K. (2015). Blood pressure
control in patients with hypertension: A retrospective cohort study. Journal of Evaluation in Clinical Practice, 21(2),
313-319. doi:http://dx.doi.org/10.1111/jep.12318

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