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Women’s Health

Ovarian
Cysts Beyond the basics
by Dr Ng Ying Woo

O
varian cysts are closed, sac-like structures within the ovary that Diagnosis
are filled with a liquid or semisolid substance. Ovarian cysts are Ovarian cysts can sometimes
common and develop over time in the course of a woman’s life. be detected during a pelvic
Fortunately, the vast majority of such cysts are harmless (benign) as they are examination, although an imaging
functional cysts. These functional cysts often disappear without treatment test, usually a pelvic ultrasound,
within a few months. is necessary to confirm the
Ovarian cysts occur in women of all ages, although they are more diagnosis. Ultrasound of the pelvis
prevalent during infancy, adolescence and during the childbearing years. can also provide information
Some women with ovarian cysts may have pain or pelvic pressure, while about the cyst’s size, location, and
many others have no symptoms. Occasionally, surgery may be required to other important characteristics
remove cysts larger than 5cm in diameter, especially if there are concerns that may raise suspicions of
of malignancy. cancer. Doppler flow studies are
Ovarian cysts may be classified according to whether they are a variant often coupled with the ultrasound
of the normal menstrual cycle (i.e. functional cysts), or not. Functional cysts examination to improve
include the commonly seen follicular cysts or corpus luteum cysts after sensitivity. Computed tomography
ovulation. Theca lutein cysts are found in early pregnancy due to excessive (CT) scan or magnetic resonance
HCG levels. imaging (MRI) is sometimes used,
but less commonly.
Non-functional Cysts Although ovarian cancer is
• Polycystic ovaries. In polycystic ovary syndrome (PCOS), these follicles not the most common cause of
remain at the surface of the ovary, creating a “many cysts” image on an ovarian cysts, many women who
ultrasound scan. are diagnosed with a cyst are
• Endometriosis. In women with endometriosis, tissue from the lining of concerned that they could have
the uterus grows in other areas of the body such as the ovaries. It can be cancer. Nevertheless, ovarian
very painful and can affect fertility. These women can develop a type of cancer is more likely in those with:
ovarian cyst called an endometrioma, or “chocolate cyst”. • A family history of ovarian
• Cystadenomas (non-cancerous growths). These cysts form out of cells on cancer.
the surface of the ovary. They are often fluid-filled. • Previous personal history of
• Dermoid cysts. This type of cyst contains tissue similar to that in other breast or gastrointestinal cancer.
parts of the body. That includes skin, hair, and teeth. Most dermoid cysts • Complex cysts (cysts with solid
are benign, but rarely, they can be cancerous. areas, nodules on the surface or
multiple fluid-filled areas).
Signs and Symptoms • Fluid collection in the pelvis or
Ovarian cysts often don’t cause any symptoms. However, they can cause abdomen (ascites).
problems if they twist, bleed, or rupture. These events lead to sudden sharp
pain and bloating in the abdomen. Women with torsion (twisting) of an The following additional blood
ovary may feel pain along with nausea and vomiting. tests may be done:
Occasionally, large ovarian cysts may press on the bladder, causing • A “Ca-125 test”, to look for
frequent urination or difficulty in emptying the bladder completely. possible cancer if you have an

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Women’s Health

abnormal ultrasound or during Laparoscopy is now the preferred approach


or after menopause.
• Hormone levels (such for benign ovarian cysts because it is
as LH, FSH, estradiol associated with a smaller scar, faster
and testosterone).
• Pregnancy test (serum HCG).
recovery, lower cost, and lower frequency of
postoperative adhesion formation.
Treatment
In premenopausal women, • Simple ovarian cysts that are larger than 10cm
ovarian cysts often resolve on • Women who are near or past menopause
their own within one to two
months, without treatment. In Surgery
postmenopausal women, ovarian In the last decade, we have seen a paradigm shift from open surgery to
cysts are less likely to resolve. laparoscopic surgery. Laparoscopy is now the preferred approach for
There is no effective medical benign ovarian cysts because it is associated with a smaller scar, faster
treatment for ovarian cysts. recovery, lower cost, and lower frequency of postoperative adhesion
formation. Fortunately, most ovarian surgeries are for benign disease and
Next steps  can be performed laparoscopically. Traditional open method is still safer
Depending on the results of the and more appropriate when there are dense adnexal adhesions, or when
imaging test, age of the patient, there is a high suspicion of malignancy. 
symptoms, results of blood
tests, and family history, we A “Scarless” Way to Make Cysts Disappear
may recommend either watchful SILS, or single incision laparoscopic surgery, is a new laparoscopic
waiting or surgery. treatment for ovarian cysts [Figure 1]. This approach aims to maximise
If a cyst is large, causing the cosmetic benefit of laparoscopy and reduce morbidities for patients.
pain, or appears suspicious The surgery involves a single, small (< 2cm) incision at the umbilicus.
for cancer, treatment usually This incision is well “hidden” within the umbilicus resulting in an excellent
involves surgery to remove cosmetic outcome for our patients. Coupled with the use of chemo-
the cyst or the entire ovary. coagulation agents, the surgery offers an almost “scarless” outcome with
minimal damage to the ovarian tissue. An initial pilot study done at our
Surgery is more likely to be centre showed excellent cosmetic outcome and high patient satisfaction.
needed for:
• Complex ovarian cysts that do Conclusion
not resolve Although ovarian cysts are commonly found in many of our female
• Cysts that are causing patients, a majority of them do not require any intervention. The general
symptoms and do not resolve approach is to reassure and continue the surveillance with a high index
of suspicion for possible malignancy. If
surgery is needed, it is appropriate to
time it with the fertility consideration of
the patient. With the introduction of SILS,
we have raised the bar in the treatment
of ovarian cysts, thereby ensuring high
patient satisfaction.

Dr Ng Ying Woo is a Consultant at


the National University Hospital. He
is also an Assistant Professor at the
National University of Singapore. His
current practice at NUH includes
all areas of general Obstetrics and
Gynaecology, with special interest in
single incision laparoscopic surgery
Figure 1. Single incision laparoscopic surgery (SILS) is a new (SILS). He has performed more than
laparoscopic treatment for ovarian cysts. 200 cases of SILS to date.

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