Antibiotics:

Inhibits/Mechanism Classification Medication

Penicillinase Sensitive
Natural Penicillins Penicillin G: Na, K, Procainic, Benzathine
(Narrow Spectrum) Penicillin V: VO
Aminopenicillins Ampicillin
(Broad Spectrum) Amoxicillin
Penicillins Penicillinase Resistant (Very Narrow Spectrum) Anti-Staph Penicillins
Methicillin Nafcillin Oxacillin Dicloxacillin
Cell Antipseudomonal (extended spectrum)
Wall Carboxipenicillins Ticarcillin Carbenicillin
Ureidopenicillins Azlocillin Mezlocillin Piperacillin
S
1 Generation
st
Cefazolin Cephalexine Cephapirin
Y Beta
N Lactams Cefadroxil Cephadrine Cephalotin
T 2nd Generation Cefuroxime Cefoxitin Cefotetan
H Cefamandole Cefonicid Cefaclor
E Cefprozil Cefmetazole
S Cephalosporins 3rd Generation Cefoperazone Ceftriaxone Ceftazidime
I Cefpodoxime Ceftizoxime Cefotaxime
S Cefdinir Ceftibuten Cefixime
Cefditoren
4th Generation Cefepime Cefpirome
5th Generation Ceftaroline
Carbapenems Meropenem Ertapenem Doripenem Imipenem-Cilastatin
Monobactams Aztreonam
Beta Lactam/Beta Lactamase Amoxicillin- Ampicillin- Piperacillin- Ceftolozane- Ceftazidime- Meropenem-
Inhibitor Combination Clavulanate Sulbactam Tazobactam Tazobactam Avibactam Vaborbactam
No Lactam Glycopeptides Vancomycin Bacitracin Oritavancin
Dalbavancin Polymyxin B Teicoplanin
Telavancin
Lipopeptide Daptomycin
Aminoglycosides Gentamycin Neomycin Streptomycin
30S Amikacin Tobramycin
Tetracyclines Doxycycline Demeclocycline Minocycline
Tetracycline Tigecycline
Protein Oxazolidonones Linezolid Tedizolid
Synthesis Streptogramins Quinupristin Dalfopristin
50S Miscellaneous Chloramphenicol
Macrolides Erythromycin Azithromycin Clarithromycin Fidaxomicin
Lincosamides Clindamycin Lincomycin
DNA Fluoroquinolones (2nd) Ciprofloxacin (2nd) Norfloxacin (2nd) Ofloxacin (3rd) Levofloxacin
Topoisomerases (Generations) (3 ) Sparfloxacin
rd
(4 ) Moxifloxacin
th
(4 ) Gatifloxacin
th
(4th) Gemifloxacin
Quinolone Nalidixic Acid
Folic Acid Sulfonamides Sulfamethoxazole Ag Sulfadiazine Sulfasalazine Sulfisoxazole
Synthesis DHFR Inhibitors Trimethoprim Pirymethamine
Radicals damage DNA Nitroimidazole Metronidazole
mRNA synthesis, inhibits transcription Rifampin Rifabutin
Inhibits protein, DNA, RNA cell wall synthesis Nitrofurantoin
Antifungals:
Protein Synthesis Flucytosine
Ergosterol Azoles Imidazoles Clotrimazole Ketoconazole Terconazole Terbinafine Micanazole
Synthesis Triazoles Itraconazole Fluconazole Voriconazole Posaconazole
Prodrug Isavuconazonium
Benzylamine Butenafine
Allylamines Terbinafine Naftifine
Ergosterol in cell wall Polyenes Amphotericin B Nystatin Natamycin
causing leakage
Glucan in cell wall Echinocandins Caspofungin Micafungin Anidulafungin
Keratin precursor makes cells resistant to Griseofulvin
invasion
aminoacyl-transfer ribonucleic acid synthetase Tavaborole
Miscellaneous Antifungals Tolnaftate Hydroxystilbamidine K Iodine Sulfonamides Pencillin Undexylenic
Organisms: Gram Positive Gram Negative Anaerobes Atypicals

ESCHAPPM

Myco,Chlam
Bacteriodes

Legionella,
Ps. Aerug.
Klebsiella

Neisseria
Enteroc

Proteus
E. Coli
MRSA

MSSA

C.Diff
H. Inf

Pepto
Strep
Antimicrobials:
Penicillins: Pen G, Pen V Not VRE

Aminopenicillins Amp/Amox
Anti-Staph Meth/Ox/Naf/
Penicillins Dicloxacillin
Beta Lac/Beta Lactamase
Inhibitor Combinations
Unasyn, Augmentin Not VRE

Piperacillin/Tazo (Zosyn) Not VRE

Ceftolozane/Tazo (Zerbaxa)
Ceftazidime/Avibac (Avycaz)
1st Gen Cephalexin,
Ceph’s Cefazolin
2nd Gen Cefot/Cefproz/ cefotetan
cefoxitin
Cephalosporins
Cefurox
3rd Gen Ceftriaxone/
Cephalosporin cefotaxime/
cefpodoxime
Ceftazidime
4th Gen Ceph Cefepime
th
5 Gen Ceph Ceftaroline
Carbapenems Imi/Dori/Mero Not VRE

Ertapenem
nd
2 Gen FQs. Cipro
3rd Levo/Gati/ Moxi
CA
levo Moxi
best
Gen Gemi/Moxi
FQs.
Syn w/ Gent/
AMGs Gent/Tobra/Ami/ vanco strep D
Strepto/Neo
Macrolides Clarith/Azith/
Erythromycin
Fidaxomicin
Lincosamides Clindamycin CA
Sulfonamides TMP/SMX CA legionella
Tetracyclines Doxy/Mino/ CA No
A
Tetra
Tigecycline
Monobactam Aztreonam
PO
Glyco- Vanc/Teicop
peptides Dalba/
Oritavancin
Lipopeptide Daptomycin
Oxazolindiones
Linez/Tediz
Streptogramins Not VRE
Quini/Dalfo Faecium
only
Nitroimidazole Flagyl
Nitrofurantoin
Rifampin
Chloramphenical