LabX balance

LabX titration
LabX connect
LabX validation

Complete overview, total control

LabX instrument control software
 LabX – METTLER TOLEDO lab instrument control software

Control your measurements

from anywhere in the lab or office

Have you ever experienced laboratory software that was really easy to use? With a user interface that already
looked familiar when you first started it? LabX uses a powerful, lean interface with the same user philosophy you
already know from widely used office software packages. This means you can exploit the full potential of the
software right from the start.
Imagine controlling all your titrators and balances via a network; maintaining your data securely but easily
accessible on a central server; looking at the analysis results directly in your office or using exactly the same
method for all your titrators via the network... With LabX pro this all becomes a reality.

Check all the data from the office

With LabX, you don’t have to go to the lab to check
results. Just start LabX on your office PC and check re-
LabX
sults, change methods and review and sign off docu-
ments electronically.

Labo
Office
Review and approve reports electronically
from any computer in the network
With LabX, you don’t need to print a single
document. The review and approval process LabX
can be done electronically. Just check the
new results and methods on your PC and sign
2 them with your electronic signature.

Simplify your routine tasks

With LabX, you can simplify your tasks in
many ways: for example you can import
your sample data directly from the LIMS,
make templates for things you have to do
every day, create statistics and control charts
automatically and much more.

LabX
 Gain access to LabX directly from a balance
You can work with LabX without even touching a
computer. Balances like the METTLER TOLEDO AX allow
you to log on to LabX directly at the balance. There isn’t
any need to connect the balance to a computer either.
Just plug it directly into your company network via the Company
METTLER TOLEDO e-Link box.
network

Server

Production
LabX
Make sure the right keys
are pressed in production
LabX user management allows
you to precisely define what
particular user groups are
allowed to do and what they
are not. This not only avoids
oratory mistakes but also simplifies
the user interface for users
who just have to press the one
button.

Work in one lab while controlling

an analysis in progress in another
With LabX, everything runs in real-time.
You can see what’s happening on an
instrument from any computer in the net-
work. Start a titration with 20 samples in
one lab and follow its progress while you
perform weighing tasks in another lab.

Manage your installed base efficiently

from anywhere in the lab
LabX gives you the possibility to manage
your instruments and monitor their perfor-
mance. For instance, you can define cen-
trally how you want to calibrate your bal-
ances and set parameters to release or lock
them for job processing.
LabX comes in four different versions: LabX pro balance
and LabX light balance for balances as well as LabX pro
titration and LabX light titration for titrators. The light versions
offer most of the functionality of the pro versions, but without
networking and 21 CFR Part 11 support. For a detailed
description of the functionality of the different versions see the
table on page 11.
 LabX – METTLER TOLEDO lab instrument control software

Weigh faster – Weigh with confidence

LabX balance increases your lab productivity and allows you to achieve
a higher level of quality and regulatory compliance. Move ahead beyond
traditional paper-based weighing processes and into a powerful and secure
networked data system.

Reliable and efficient daily routine

Save time and reduce mistakes
• No manual transcription of data
• No weighing tickets on the printer
• No manual re-transcription into a LIMS-like software.
Rapid Access, just as if there were no computer
Our latest balance generation with its large touch screen
user interface allows you to log on to LabX directly from
the balance touch screen and perform your weighing
tasks without even touching a PC.
Enjoy easy and reliable data capture with the job template
For routine tasks, you can prepare your jobs in advance,
save them as job templates and reuse them as often as needed.
You will find the jobs ready-to-start in each balance job queue.
The job template ensures full traceability of settings and consis-
tency of weighing practices in your lab.
• Identification of sample, product or project
• Customization of user guidance
• Balance suitability check
• Result definition – control limits

1. 2. 3. 4. 5.

4
With the Rapid Access buttons,
select the job you want to
carry out from the job queue.
Log on to LabX from the
balance touch screen.
The balance prompts you for
your user ID and password.
LabX checks the release status Press the Print button to Retrieve data, get a printed
of the balance. You can then transfer data. report or have data automa-
follow the step-by-step guidance tically exported to a LIMS
through the job on the balance with LabX connect.
display.

LabX
Embedding quality in your weighing processes
In almost every lab, a balance is the first precision instrument used in the analysis chain. LabX balance Instrument
Management simply gives your balances the weight they deserve in your quality assurance system. Thanks to this, you
can easily check your instruments and ensure that no incorrect data is generated. And because METTLER TOLEDO manu-
factures instruments, LabX offers you an unsurpassed tool to monitor instrument performance, tailor-made for METTLER
TOLEDO balances, more comprehensive than any third-party software package.

Define your maintenance schedule and rely on LabX balance

LabX scheduler allows you to centrally define your maintenance
schedule. In addition, you can set tolerance levels appropriate to your
industry. For your convenience, METTLER TOLEDO balance tolerances
are made available from a unique built-in tolerance database. Once
these are set, LabX balance remotely controls adjustments and/or
sends reminders. All data created is stored and can be viewed. If a
balance was incorrectly adjusted, you know exactly when this hap-
pened and which samples have to be retested.

LabX scheduler with weight library and tolerance database

Sensitivity adjustment and test history, including automatic

internal adjustment.

The release control releases or locks a balance for job

execution according to user-definable parameters

Make sure that no incorrect data is generated

At the start of the job, the release control checks that
the balance meets the level of security required for
the job.You can define 3 different security levels for
releasing instruments for job processing (adjustments
validity, tests results).
Manage your applications with ease
LabX balance provides you with a set
of default simple weighing, differential
weighing and totalization application
templates so that application assembly is
greatly facilitated.
 LabX – METTLER TOLEDO lab instrument control software

Use your titrators more efficiently

Although METTLER TOLEDO titrators are well known for their simple and
straightforward user interface, LabX titration will give you an even better overview of
everything. Furthermore, it provides additional possibilities for instrument control,
method administration and the analysis of your results. Overall, LabX titration will
help you to perform your titration tasks better and easier than ever.

Prepare and execute your daily titration routines quickly

You can define your sample series in advance. Just choose a titration method and the number of samples,
and then enter your sample data. Titration begins as soon as you drag the Series icon to the desired titrator.
You can of course use the series as a template for titrations you have to perform frequently. To avoid mis-
takes and save time, you can even import the data of the batches directly from a LIMS.

Open the online window of

a titrator by clicking its icon

Double-click a method to edit it

Here you see the currently

Organize your methods in folders measured data points

Organize your daily jobs by

generating sample series templates The online window of
the selected titrator

Here you see the job queue

of this titrator

The «Analysis» tab lets you

control your titrators

Easily create new methods using the built-in database

LabX greatly simplifies method creation: Just choose the
6
«Find...» command from the method creation menu and
Always see what is going on
you can search the entire METTLER TOLEDO application
As soon as you start a titration, the online window of the
database (400+ applications) for a suitable method.
titrator displays the titration curve, its first derivative, a table
LabX will even display a compehensive description of the
of measured values and, when the titration is finished,
method including curve examples etc. The methods in
the results. If you have started multiple jobs on a titrator,
LabX look very familiar – they have the same structure,
the series list will keeps you up-to-date about progress in
functions and parameters as on the titrator. It’s also easy to
the job queue.
manage your method library. You can group your methods
in folders, export them to a file (which can be e-mailed)
or copy them to any titrator that is connected. If you need
an earlier version of the method, that’s no problem either.
Just choose «Method history» and LabX displays all the

LabX
previous versions of the method you created.
Display a well-structured overview of your results
Clicking the «Reports» tab gives you an overview of all your
titration data. Control charts as well as result overviews, raw
data tables and sample information lists are compiled with
just one click of the mouse. The unique hierarchical data
structure makes it easy to navigate quickly to what you are
looking for. In addition, you can create your specific data
filters (which can be saved for later use). The filter menu also
gives you direct access to predefined filters, for example, to
quickly display last week's results. In addition to filtering,
LabX also lets you create your own folder structure to orga-
nize your results.
Get instant statistics for results and calibrations
LabX titration automatically compiles statistical in-
formation and control charts not only for any sample
series, but also for all the data acquired with a method.
For example, if you want to have a quick look at all the
analyses done with a particular method, just double-
click the Statistics icon of that series and the control
chart is immediately displayed. With a suitable filter, you
can quickly narrow down the chart to a certain time in-
terval, e.g. «all results of last week».
LabX can also automatically generate control charts of sensor
calibration and titer determination histories.

Create the data structure you want,

e.g. a folder for every application

Click here to get an instant control

chart of all the results of one application

Click here to get an instant control

chart of all the results in the series
Control chart

Double-click to view
the titration curve

Titration curve

The Reports tab shows all

your results The currently logged in user is
always displayed here

Reevaluate your results with graphical tools

You can reevaluate all your results with 5 differ-
ent graphical methods: Tubbs, tangents, seg-
mented, extrapolation or manual.
The advantage of graphical reevaluation is that
you can later still find missing equivalence points
without having to reanalyze the sample – you see
the result marked directly on the titration curve.

Generate detailed printed or PDF reports

LabX titration allows you to print everything from methods to entire
analysis reports. Just right-click the item you want to print and choose
the Print command in the pop-up menu. Alternatively, you can also
generate a PDF with two simple mouse click. The reports are not
only extremely well formatted, they also automatically include all
the information required by GLP. The report layout editor lets you
adapt the reports to your needs, e.g. by adding a company logo.
 LabX – METTLER TOLEDO lab instrument control software

LabX supports all your regulatory needs

LabX pro balance and LabX pro titration provide you with all the tools needed for data management
and storage according to FDA regulations (21 CFR Part 11). Every user has to log on to the system with
his login and password. The user manager allows user rights to be defined for four different user groups.
Critical manipulations have to be confirmed with the user’s digital signature. Every action is recorded in
the audit trail. Every document you create in LabX can go through electronic review and approval
procedures. If your company does not require this level of security, most of the security features can be
selectively switched off. In addition, METTLER TOLEDO also offers comprehensive documentation and
support to assist you in validating your LabX pro system.

Give each user the possibilities he needs
The user manager allows you to create users and assign them
to different user groups. For each group, you can define de-
tailed user rights. In addition, you can generate profiles. These
define which instruments a user can see or use and which not.
This makes work in the network easier and more secure.
Be confident that your data is secure
All the data created and imported into LabX pro is stored in
an SQL database. It is therefore not possible to delete data
files or to otherwise manipulate data via the PC’s file system.
In a network, your data is stored on one computer only, the
server. This facilitates data backup and ensures that all the
instruments always use the same settings and methods.

Get traceability and flexibility in a multi-user environment

Even if several users are using the same PC, everyone still
has a personal LabX pro session: Simply open LabX several
times, once for each user. This is especially useful if you work
in shifts or an administrator wants to make a quick change
on a system where an analysis is running.

Define your own security policies

LabX pro allows you to define password
policies according to your company’s
guidelines or to regulatory requirements.
The policies dialog allows you to set
password expiration, minimal password

LabX
length, password complexity and more.
Review and approve documents directly within LabX
Each LabX document has a footer with approval and review infor-
mation on the screen as well as on each printout. Documents can
easily be signed with your electronic signature. The user manager
allows you to define who has the right to review or to approve
documents.

Get a quick overview of what happened with the audit trail function
The audit trail records every relevant action taken in the LabX system -
for example a logon, a change of method, or the import of a series.
The audit trail can be viewed on the screen, filtered according to vari-
ous criteria, printed and exported as a text, or as a PDF file.
The audit trail not only logs who did what, it also informs you about
old and new values.

Restore earlier method versions (titration only)

To recover earlier versions of titration methods, you
can use the method history function. This gives you
access to all the versions of a method you have
previously created or edited with LabX pro titration. Of
course, all the changes made to a method are also
recorded in the audit trail.

Get comprehensive validation support

In regulated environments, software systems have to be validated. METTLER TOLEDO offers you all
the support you need: You can use our comprehensive, two-volume validation documentation and do
it yourself or you can ask our validation specialists to do it for you.

Validation Manuals I and II

METTLER TOLEDO has created two specialized validation
manuals for LabX: Manual I contains all the necessary
information you need for vendor qualification according to
GAMP. Volume II is designed to make the whole IQ/OQ/PQ
process as standardized and rapid as possible. It contains
all the necessary forms and guides you through the testing
process. And since it’s all contained in a binder, you can
add revalidations, etc. at any time. If you want to update to a
later version of LabX, METTLER TOLEDO will provide written
revalidation guidelines as well as the necessary addendums
to the validation manuals.
 LabX – METTLER TOLEDO lab instrument control software

LabX is ready to be integrated

into your existing systems
LabX is well prepared to exchange data with most data management
systems such as Laboratory Information Management Systems (LIMS),
Laboratory Data Management Systems (LDMS), Statistical Quality Con-
trol Systems (SQC), and Enterprise Resource Planning Systems (ERP).
LabX can also exchange data with other instrument control packages
such as chromatography data systems (CDS). Of course, data can also
simply be exported or copied into spreadsheets like Microsoft Excel.

Manual and automatic export with LabX pro

LabX pro offers many possibilities for the import and export of data.
You can specify which parts of the reports you want to export. During
export, LabX pro generates an Excel-compatible ASCII file. Export can be
automated by sending the export file automatically to a local or network
directory.

Fully customized import/export with LabX connect

LabX connect, which is available as an option, allows a high degree of
customization of the automatic export functionality. Furthermore it also
offers automatic import of series and method data. For more information
on LabX connect, please ask for the LabX connect datasheet.

LabX technical information

SQL server compatibility
LabX is delivered standard with the Microsoft MSDE (Microsoft Database Engine). However, LabX can also be
used with a full installation of Microsoft SQL Server 7.0 or Microsoft SQL Server 2000. The installation program
detects an existing version of the SQL server and automatically integrates LabX into it.

Networking
LabX pro is composed of 6 installation components that can be independently installed on different computers.
The components are:
• Client component (multiple possible)
• DeviceServer component (multiple possible)
• Broker component (only one per networked system)
10
• Database component (only one per networked system)
• DBMaintenance (to be installed on the same system as the database)
• Audit Trail (multiple possible)

The Client component includes the files that make up the user interface. It is typically installed on every PC on which you
want to use LabX pro.
The DeviceServer component includes the files that are responsible for communication with the instrument. It can be in-
stalled more than once in a system, typically on all systems that have instruments attached.
The Broker component includes the files that make up the business logic. This component must not be installed more than
once on a system. Typically it is installed on the server.
The Database component includes the database files. This component is installed on the network server.
DBMaintenance serves as a backup and database maintenance tool. It offers automatic and manual backup, restore and
other database related tasks.
The Audit Trail is an independent application for viewing, searching and exporting the audit trail. It can be started from
within LabX or independently.
 Overview of Features LabX LabX LabX LabX
pro light pro light
balance balance titration titration
Instruments supported
Control of METTLER TOLEDO AX, MX, UMX, AG, XS, XP, PR, SR, PG-S, SG, AT, MT, UMT balances • •
Control of METTLER TOLEDO DL50 Graphix/Rondolino, DL53, DL55, DL58, DL70ES, DL77, • •
DL31, DL32, DL38, DL39 titrators
Job management
LabX b alanc e

User guidance on the balance display • •

Rapid Access (AX, XP balances only) - Log on directly from the balance •
Online view • •
Job template editor • •
Weighing, differential weighing and totalization applications • •
Job queue • •
Balance settings management • •
Instrument management
Instrument release control • •
Sensitivity adjustments and performance tests scheduler and controller • •
Sensitivity adjustments and performance tests histories, incl. FACT and ProFACT • •
Tolerances management with built-in tolerance database • •
Weights library • •
MinWeigh incident history • •
Calibration certificate explorer • •
Instrument control
LabX titr ation

Unlimited number of titrators per PC (recommended 1-3, LabX light can only control one titrator) •
Online titration curves with derivatives, table of measured values, job queue status • •
Electrode calibration and titer statistcs • •
Remote control of manual titrator/sample changer functions such as stir, dispense, etc. • •
Method editor with integrated database of 400+ methods including full description • •
Sample/batch editor • •
Graphical reevaluation of results (Tubbs , tangents, segmented, extrapolation and manual) • •
Instrument management
Editing of instrument resources such as titrants, sensors etc. • •
Instrument documentation management and DataX support •
Full instrument resource/settings backup and transfer • •
Import and export of methods (can be automated with the optional LabX connect) • •
User defineable report data structure and user defineable data (e.g. results of manual titrations) •
Data management
LabX c ommon f eatur e s

Results stored in SQL database • • • •

Powerful database search/filter function • • • •
Control charts • •
Flexible statistical evaluation • • • •
Report generator for automatic GLP-compliant reports • • • •
Manual export to EXCEL or LIMS • • • •
Automatic export to EXCEL or LIMS • •
Bidirectional, fully configurable and automated communication with LIMS available as an • •
option (LabX connect)
Copy / paste of tables, lists and pictures into Microsoft Word, Excel or other similar software • • • •
packages supporting OLE
Database tool for manual/automated backup and maintenance • • • •
21 CFR Part 11 compliance
User manager • •
Password management functions • •
Electronic signature and approval/sign-off of documents • •
Audit trail with full search and export functionality • •
System
Full network capability, instruments directly connectable via Ethernet • •
Client/server architecture: all data can be put on a central database server • •
Integrated help system • • • •
Mettler-Toledo GmbH, Quality certificate. Development,
Analytical, production and testing according to
CH-8603 Schwerzenbach, Switzerland ISO9001. Environmental manage-
Phone +41-44-806 77 11, Fax +41-44-806 73 50 ment system according to ISO14001.
Internet: http://www.mt.com
Worldwide service. Our extensive
AT Mettler-Toledo Ges.m.b.H., A-1100 Wien service network is among the best
Tel. +43-1-604 19 80, Fax +43-1-604 28 80 in the world and ensures maximum
AU Mettler-Toledo Ltd., Port Melbourne, 3207 Victoria availability and service life of your
Tel. +61-1300 659 791, Fax +61-3-9645 3935 product.
BE N.V. Mettler-Toledo S.A., B-1932 Zaventem
Tel. +32-2-334 02 11, Fax +32-2-334 03 34 European conformity. The CE con-
CA Mettler-Toledo, Inc., Mississauga, Ontario L4V 1J2 formity mark provides you with the
Tel. +1-800-638 8537, Fax +1-905 612 8094 assurance that our products comply
CH Mettler-Toledo (Schweiz) AG, CH-8606 Greifensee with the most recent EU directives.
Tel. +41-44-944 45 45, Fax +41-44-944 45 10
CN Mettler-Toledo (Shanghai) Ltd., Shanghai 200233
On the Internet. You will quickly find
Tel. +86-21-6485 0435, Fax +86-21-6485 3351
lots of essential information about
CZ Mettler-Toledo, s.r.o., CZ-10000 Praha 10
our products, our services, and our
Tel. +420-2-72 123 150, Fax +420-2-72 123 170
company at http://www.mt.com
DE Mettler-Toledo GmbH, D-35353 Giessen 11
Tel. +49-6-41 50 70, Fax +49-6-41 507 319
This brochure is printed on environ-
DK Mettler-Toledo A/S, DK-2600 Glostrup
Tel. +45-4327 0800, Fax +45-4327 0828
mentally friendly paper.
ES Mettler-Toledo S.A.E., E-08908 L´Hospitalet del Llobregat
Tel. +34-93-223 76 00, Fax +34-93-223 76 01
FR Mettler-Toledo s.a., F-78222 Viroflay Cedex
Tel. +33-1-3097 1717, Fax +33-1-3097 1773
HK Mettler-Toledo HK Ltd., Cheun Sha Won Kowloon
Tel. +852-2744 1221, Fax +852-2744 6878
HR Mettler-Toledo, d.o.o., HR-10000 Zagreb
Tel. +385-1-292 06 33, Fax +385-1-295 81 40
HU Mettler-Toledo, Kft, H-1139 Budapest
Tel. +36-1-288 40 40, Fax +36-1-288 40 50
IN Mettler-Toledo India Pvt. Ltd, 400 072 Mumbai
Tel. +41-1-944 45 45, Fax +41-1-944 45 10
IT Mettler-Toledo S.p.A., I-20026 Novate Milanese
Tel. +39-2-333 321, Fax +39-2-356 29 73
JP Mettler-Toledo K.K., Ohta-ku Tokyo 143-0006
Tel. +81-3-5762-0606, Fax +81-3-5762-0756
KR Mettler-Toledo (Korea) Ltd., Seoul 137-130
Tel. +82-2-3498 3500, Fax +82-2-3498 3555
KZ Mettler-Toledo C.A, 480009 Almaty
Tel. +7-3272-980 834, Fax +7-3272-980 835
MY Mettler-Toledo (M) Sdn. Bhd. 40150 Shah Alam
Tel. +60-3-7845 5773, Fax +60-3-7845 8773
MX Mettler-Toledo S.A. de C.V., México C.P. 06430
Tel. +52-55-554 75700, Fax +52-55 554 12366
NL Mettler-Toledo B.V., NL-4004 HA Tiel
Tel. +31-344 63 8363, Fax +31-344 63 8390
PL Mettler-Toledo, Sp. z o.o., PL-02-924 Warszawa
Tel. +48-22-651 92 32, Fax +48-22-651 71 72
RU Mettler-Toledo C.I.S., 101000 Moscow
Tel. +7-095-921 92 11, Fax +7-095-921 63 53
SE Mettler-Toledo AB, S-12008 Stockholm
Tel. +46-8-702 50 00, Fax +46-8-642 45 62
SG Mettler-Toledo (S) Pte. Ltd., 139959 Singapore
Tel. +65-689 000 11, Fax +65-689 000 12
SK Mettler-Toledo s.r.o, SK-82 104 Bratislava
Tel. +421-43 42 74 96, Fax +421-43 33 7 190
SI Mettler-Toledo, d.o.o., SI-1236 Trzin
Tel. +386-1-562 18 01, Fax +386-1-562 17 89
TH Mettler-Toledo (Thailand), Huy Kwang Bangkok 10310
Tel. +66-2-723 0300, Fax +66-2-719 6479
TW Mettler-Toledo Pac Rim AG, Taipei
Tel. +886-2-2579 5955, Fax +886-2-2579 5977
UK Mettler-Toledo Ltd., Leicester, LE4 1AW
Tel. +44-116-235 70 70, Fax +44-116-236 63 99
US Mettler-Toledo, Inc., Columbus, OH 43240-2020
Tel. +1-614-438 4511, Fax +1-614-438 4900
L.A. Mettler-Toledo, Latin America, Miami, FL 33122-1528
Tel. +1-305-351 2442, Fax +1-305-351 2425

For all other countries:

Mettler-Toledo GmbH
PO Box VI-400, CH-8606 Greifensee
Phone +41-44-944 22 11, Fax +41-44-944 31 70

Subject to technical changes.

© 09/2004 Mettler-Toledo GmbH
Printed in Switzerland 51724345C