Oogenesis

Dr Navneet Kumar
Professor (Anatomy)
K.G.M.U
Dr NavneetKumar Professor
Anatomy KGMU Lko
 Oogenesis
• Development of ovum (oogenesis)
• Maturation of follicle
• Fate of ovum and follicle

Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
 Oogenesis

• Site – ovary
• Duration – 7th week of embryo –primordial germ cells
• -3rd month of fetus –oogonium
• - two million primary oocyte
• -7th month of fetus primary oocyte +primary follicle
• - at birth primary oocyte with prophase of
• 1st meiotic division
• - 40 thousand primary oocyte in adult ovary
• - 500 primary oocyte attain maturity
• - oogenesis completed after fertilization

Dr Navneet Kumar
Dr NavneetKumar Professor Professor (Anatomy)
Anatomy KGMU Lko K.G.M.U
 Development of ovum
Oogonium(44XX)
-In fetal ovary
Primary oocyte (44XX)
arrest till puberty in
prophase of 1st phase
meiotic division
Secondary oocyte(22X)+Polar
body(22X)
1st phase meiotic division
completed at ovulation
&enter in 2nd phase
Ovum(22X)+polarbody(22X)
After fertilization

Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
 Dr Navneet Kumar
Dr Professor
NavneetKumar Professor
(Anatomy)
K.G.M.U
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Maturation of follicle

Dr NavneetKumar Professor
Anatomy KGMU Lko
 Maturation of follicle
Primordial follicle
-Follicular cells
Primary follicle
-Zona pallucida
-Granulosa cells
Secondary follicle
Antrum developed
Ovarian /Graafian follicle
- Theca interna &externa
-Membrana granulosa
-Antrial cavity
-Discus proligerus
-Cumulus oophoricus

Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Ovulation

Dr NavneetKumar Professor
Anatomy KGMU Lko
 Structure of ovum
• Secondary oocyte
• Vitellus
• Nucleus
-phase of 2ed meiotic division
• Vitelline membrane
• Previtelline space
1st polor body
• Zona pellucida
• Corona radiata

Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
 Fate of ovarian follicle

Formation of Corpus
luteum
• After ovulation ovarian
follicle Ruptured and
folded
Corpus luteum
• Follicular
cells/granulosa cells
-Cells of membrana
granulosa
-lutien pigment
• Luteal cells
• Theacal cells

Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
 Corpus luteum

• Corpus luteum of pregnancy

• Corpus luteum of menstruation

Dr NavneetKumar Professor
Anatomy KGMU Lko
Fate of follicle

Dr NavneetKumar Professor
Anatomy KGMU Lko
 Fate of follicle

• Corpus luteum
-Corpus albicans
• Corpora atretica
-interstitial gland

Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
Dr NavneetKumar Professor
Anatomy KGMU Lko
 M.C.Q .1.
Oogenesis starts
(a) at puberty
(b) after birth
(c) at early fetal life
(d) during ovulation

Dr NavneetKumar Professor
Anatomy KGMU Lko
 M.C.Q .2.
Secondary oocyte are formed
(a) after fertilization
(b) at birth
(c) at early fetal life
(d) after ovulation

Dr NavneetKumar Professor
Anatomy KGMU Lko
 M.C.Q .3.
Unovulated ovarian follicle coverts as
(a) corpus luteum
(b) interstitial gland
(c) luteal gland
(d) tertiary follicle

Dr NavneetKumar Professor
Anatomy KGMU Lko
 M.C.Q .4.
After fertilization , corpus luteum may persist up to
(a) 14 days
(b) 28 days
(c) 3 months
(d) 9 months

Dr NavneetKumar Professor
Anatomy KGMU Lko
 M.C.Q .5.
Zona pallucida is present around
(a) ovum
(b) theca interna
(c) membrama granulosa
(d) corpus luteum

Dr NavneetKumar Professor
Anatomy KGMU Lko