6-Gingerol & Arecoline

Ester

Arecoline Alkene

Physical Property

Molecular formula : C8H13NO2

Molecular weight : 155.197 g/mol
Boiling point : 209 °C
Melting point : <25°C
Format: Oily liquid Amine
Solubility : water solubility - 1000000 mg/L at 25°C
pKa : 7.1611
Background info & Application

- Arecoline is an alkaloid obtained from the betel nut, fruit of a palm tree or
found in nut.
- It is used to form varous salts as a ganglionic stimulant, a
parasympathomimetic and a vermifuge.
- Soluble in water, alcohol, and ether.
- It has been used as a euphiriant in the pacific island.
- Alzheimer’s disease is cognitive decline and arecoline was suggested as a
treatment. It shows modest verbal and spatial memory improvement in
alzheimer’s patients.
- Can be used to treat cocaine abusers and maintain them on treatment
programs of slow withdrawing from the drug
6-Gingerol Ketone Alcohol
Benzene
Physical Property

Molecular Formular: C17H26O4

Molecular Weight: 294.391 g/mol
Boiling point: 453 °C
Melting point: 30.32 °C
Format: Pungent yellow oil Ether
Solubility: Soluble in methanol and ethanol
pKa: 10.02
Background Information & Application

- Gingerol is a compound separated from the root of the ginger.

- Lower Blood Sugar
- It has the anti-emetic properties due to its ability to inhibit the anti-serotonin 3
receptor function.
- It’s also has a great anti-inflammatory which reduces pain and soreness, and
antioxidant effect which prevents the producing of free radical which damage
cells (Leech, 2017).
- It is considered as worldwide herbal medicine, which reduces the risk of many
diseases, such as cancer.
Bibliography:
Compound Summary for CID 2230. (n.d.). Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/arecoline

Craig, P., Gasser, R., Parada, L., Cabrera, P., Parietti, S., Borgues, C., Acuttis, A., Agulla, J., Snowden, K. and Paolillo,
E. (2018). Diagnosis of canine echinococcosis: comparison of coproantigen and serum antibody tests with arecoline
purgation in Uruguay.

Leech, J. (2017). 11 Proven Health Benefits of Ginger. Retrieved from

https://www.healthline.com/nutrition/11-proven-benefits-of-ginger

Shih YT, e. (2018). Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative
stress and suppression of the antioxidant prote... - PubMed - NCBI. [online] Ncbi.nlm.nih.gov. Retrieved from
https://www.ncbi.nlm.nih.gov/pubmed/20691257
Bibliography:

Showing Compound (S)-[6]-Gingerol (FDB001108). (n.d.). Retrieved from http://foodb.ca/compounds/FDB001108

Young, H., Luo, Y., Cheng, H., Hsieh, W., Liao, J. and Peng, W. (2018). Analgesic and anti-inflammatory activities of
[6]-gingerol.

6-Gingerol. (n.d.). Retrieved from https://www.kerafast.com/product/1194/6-gingerol

6-Gingerol(23513-14-6). (n.d.). Retrieved from https://www.chemicalbook.com/ProductMSDSDetailCB4328683_EN.htm