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The affective disturbance which commonly occurs tum significantly more severely than in the non-puer-
in the first two weeks following childbirth (“the peral state has been shown by Knight and Thirkettle
blues”) is thought to be a normal transient part of the (71. They also demonstrated that the method of
early puerperium [ 1,2]. There is now increased recog- measuring postnatal mood change is vitally important
nition of, and interest in, the association between this and suggested that this is because the experience is one
mood disturbance and childbirth [3-61. Whether the of overall affective dysphoria rather than a depressive
blues is truly a minor transitory occurrence, or whether syndrome.
it is associated with more severe and clinically sig- The reported incidence of postnatal blues varies
nificant postpartum disorder remains unclear and is the from 34-79% [8,9].This is at least partly explained by
subject of this paper. the general lack of agreement about the definition of
Although mood change after childbirth is accepted the blues. Descriptive studies have yielded prevalence
as common, no clear definition of the blues exists and rates for individual symptoms occurring postpartum;
hence there are no widely accepted rating scales. That tearfulness, depression, anxiety, insomnia, headaches,
negative affective symptoms are experienced postpar- confusion and fatigue have all been commonly
reported [2,10]. However, no clear inclusion criteria
exist at this stage. Emotional lability was thought to be
Department of Psychiatry and Rehavioural Science, University an important component of the blues [ 11-13], but is
of Auckland, Private Bag, Auckland, New Zealand
not part of Pitt [ 2 ] or Stein’s [ 101 rating scales. The
Catherine C Hapgood FRANZCP, Research Fellow
blues are thought to be transient, but temporal limits
Gail S Elkind PhD, Associate Lecturer
remain arbitrarily defined. The expected level of emo-
James J Wright MD, FRACP. MRCPsych, FRANZCP, Associate
Professor and Head of Department.
tional intensity in a minimal case ranges from that of
Yalom who will accept an isolated episode of weep-
300 MATERNITY BLUES AND POST PARTUM DEPRESSION
ing in the postnatal period, to pre-determined scores using instruments similar to, or identical with, those in
on clinical rating scales [2,10]. earlier studies, in a prospective design. A factor
Literature which has addressed the question of analysis of the “blues” VAS was also carried out, to
whether the blues is related to maternal mental state in permit more precise definition of the mental
either pregnancy or postpartum is confounded by the phenomena involved in the concept of “blues”.
use of different instruments and time scales, making
direct comparisons difficult. Yalom et al’s [ I ] study Method
was essentially a descriptive account of mood change
postpartum - 22 of their initial sample of 39 women The sample consisted of women randomly selected
were telephoned at eight months postpartum, and only from six ante-natal clinics at the National Women’s
Aust NZ J Psychiatry Downloaded from informahealthcare.com by University of Auckland on 01/13/15
one reported prolonged mood change since the puer- Hospital, Auckland, and a nearby private obstetric
perium. Davidson [ 141 and subsequent workers practice. This was done to ensure a sample repre-
[ 15,16,10,17] all found an association between sentative of women delivering at the hospital. Ex-
lowered mood in late pregnancy and greater distress in clusion criteria initially applied were an inability to
the early puerperium. In addition, Handley [ 161 and speak English and a planned house move out of the
Stein [ 101 both found an association between depres- area in the next twelve months.
sion in the first 6 months and 3 months respectively The women were approached at 34 weeks of preg-
after childbirth, and antenatal distress with more nancy and asked whether they would take part in the
severe symptoms in the puerperium. In both these study. They were given verbal and written information
studies later depression requiring a visit to the general about the purpose of the study, and assured of con-
practitioner, and in Stein’s [ 101 study the Self Rating fidentiality. Two weeks later the initial research inter-
For personal use only.
Questionnaire used to assess the blues was also used view was conducted. Demographic data were
to measure depression at 3 months postpartum. obtained, followed by a clinical interview. History of
Paykel [ 181 found an association between postnatal psychiatric illness, family psychiatric history, past his-
depression at 6 months postpartum and a history of the tory of postnatal depression, whether the pregnancy
blues, in cases in which there was an absence of un- was planned, past history of abortions (both spon-
desirable life events. The clinical account of the blues taneous and induced) and whether breast feeding was
was gained retrospectively in this study at the time of planned, were recorded.
the single assessment interview. The woman’s attitudes to her mother were assessed
Kendell et al [ 191 used daily visual analogue scales using visual analogue scales for dependency, close-
(VAS) to assess mood change in the first 3 weeks ness, identification with, feelings of fondness for and
postpartum, and then used a standardised psychiatric mixed feelings about mother. These five scales were
interview (Goldberg et al. 1970) between 3 and 5 chosen on the basis of their face validity, in the absence
months postpartum to diagnose depression. Higher of established standard instruments.
depression and lability ratings together with a more Whether or not the woman’s own parents were alive,
pronounced 5 day peak on the daily ratings, were living close by, and any separations from them in
found in those women who were depressed postpar- childhood were also recorded.
tum. This was followed by a standardised psychiatric in-
However, Kumar and Robson [21] used the same terview [20]. The rater (CCH) was a psychiatrically
psychiatric interview [20] at 3 months postpartum in a trained interviewer who had received formal training
prospective design, but failed to show an association in the use of the instrument (as requested by the desig-
between depression post-natally and either General ners). (Control studies for inter-rater reliability have
Health Questionnaire (GHQ) scores at I week postpar- been performed on an independent sample of subjects
tum or a retrospective account of the blues. Their together with a proportion of the main sample and will
sample consisted of middle class primiparous women be reported elsewhere. Ratings obtained by two
of higher social class than those of Kendell et al‘s [ 191 qualified psychiatrist raters were similar.) The
randomly selected sample, and they did not use daily Goldberg interview was then re-administered at 6
rating scales in the immediate postpartum period. weeks 3 months 6 months and 14 months postpartum.
The present study aimed to clarify the association Following delivery, details about the spontaneity of
between “the blues” and post-partum depression by onset of labour and the length of Stage I and Stage I1
CATHERINE C. HAPGOOD, GAIL S. ELKIND & JAMES J. WRIGHT 30 I
were the same VAS as used by Kendell et al [19]. Using the woman’s occupation, the social class dis-
Knight & Thirkettle [7] found VAS ratings to be the tribution was 2 1 % in Classes 1 and 2,41% in 3 and 4,
most sensitive method of measuring puerperal mood 19% in 5 and 6; 19% had never held jobs in the paid
state. The VAS were provided in a booklet for the sub- work force. Using the partner’s occupation, the social
jects. No titles for the scales were given. The women class distribution was: 31% in 1 and 2, 49% in 3 and
were given instructions to fill in their booklet at the 4, and 16% in 5 and 6. Four percent of the partners
same time each day (early evening) and asked to be as were not working. (The Revised SE index distribution
honest as they could in rating how they had felt in for New Zealand male work force is 1 & 2=2 1 c/o, 3 &
general on each scale over the past 24 hours. If they 4=5 1%, 5 & 6=20%). At the time of the initial research
missed a day they were asked to leave the page blank interview 52% of the sample were employed and 48%
For personal use only.
and fill in the next days page. They were asked not to described their normal occupation as household
compare their previous ratings. At the same times as duties.
the VAS ratings they were also asked to rate the quan- The DSM-111 axis I diagnoses made in the postpar-
tity and quality of their sleep the previous night and tum period were major depressive disorder, adjust-
whether the baby had been predominantly restless or ment disorder with depressed mood, and adjustment
settled in the past 24 hours. All women were seen on disorder with mixed emotional features (depression
the 2nd-3rd day postpartum to check that they had and anxiety). There were 2 cases of adjustment disor-
remembered to take the booklet to hospital with them der with anxious mood at 6 weeks postpartum.
and to check again that they fully understood the in- Eighteen women were diagnosed as having major
structions. Ninety five women returned completed depressive disorder at some stage, 10 of whom had no
questionnaires at the 6 weeks postpartum interview. diagnosis in the antenatal period and were therefore
On each occasion when the Goldberg Standardised new cases. The total score on the Goldberg, i.e. the
Psychiatric Interview was administered, a DSM-111 symptom score plus twice the mental state rating,
Axis I diagnosis was made (again by CCH), and therefore essentially represented the severity of affec-
Research Diagnostic Criteria (Spitzer et a1 [ 2 2 ] were tive disorder postpartum.
applied. The verbatim transcripts of a proportion of in-
terviews where a diagnosis had been made were dis- Strategy for Overall Data Analysis
cussed with two other psychiatrists (JMK & JJW) and
agreement on diagnosis was reached with that of CCH 66 subjects completed all of the VAS on all 14 days
in all instances examined.A total Goldberg score was postpartum. Some summarising of the daily data items
also calculated for each interview using Goldberg’s was necessary to make a factor analysis feasible. This
method, i.e. the sum of all the symptom scores, plus was done by adding together the scores over several
twice the mental state rating. A further overall rating days (1-5) (6-9) (10-14) for each mood scale. This
was also made which gave an indication of severity of resulted in minimal distortion of the raw data, in the
disorder on a 5 point scale (0 = No symptoms, 1 = sense that this data smoothing accounted for more of
symptoms of minor significance for which no treat- the total variance after factor analysis than other
ment is necessary 2 = symptoms requiring intervention methods of collapsing the data across time. It also
by a general practitioner, 3 = psychiatric intervention produced the most clinically meaningful factors. The
required. 4 = inpatient psychiatric treatment needed). resulting 18 items were subjected to a principal com-
302 MATERNITY BLUES AND POST PARTUM DEPRESSION
Items Factors
Early Mlddie Late Happiness Lability
Unhapplness Unhappiness Unhapplness
Days 1-5:
-Depression .83
-Tearfulness .a0
Aust NZ J Psychiatry Downloaded from informahealthcare.com by University of Auckland on 01/13/15
-Anxiety .88
-Irritability .68
Days 6-9:
-Depression .76
-Tearfulness .79
-Anxiety .62
-Irritability .87
Days 10-14:
-Depression .83
-Tearfulness .82
-Anxiety .58
-Irritability .75
For personal use only.
Happiness:
-Days 1-5 .71
-Days 6-9 .91
-Days 10-14 .90
Lability:
-Days 1-5 .82
-Days 6-9 .82
-Days 10-14 .87
ponents analysis with varimax rotation. Five factors 2, table 2). Thus, the predictive usefulness of the col-
were identified. These factors were tentatively lective factor scores was measured after controlling for
labelled early unhappiness, middle unhappiness, late the effects of immediate pre-natal state.
unhappiness, happiness and lability. Items were as- Heading 3, table 2, shows the unique predictive value
signed only to the factor on which they had the highest of each factor after the other four factors have been
loading; the lowest of these loadings was .58 (see partialled out first.
Table 1). Five “blues factor scores” subsequently A critical assessment was then applied to the results
created for each subject each consisted of the sum of to exclude alternate logical associations, namely:
the unweighted item scores divided by the numbers of (a) Mann-Whitney U tests were used to compare
items on that factor [24]. primigravidae with multigravidae on each blues fac-
A two-stage general linear modelling procedure was tor. They did not differ significantly on any of the 5
then used to establish predictive relations between factor scores by Mann-Whitney U tests. Prediction of
these “blues” factor scores and outcome measures of T scores from blues factors was repeated using two
depression. First, the outcome measures were separate groups i.e., primiparae vs multiparae and very
predicted from the Goldberg scores at the 36th week little difference was found. Parity did not therefore
of pregnancy (heading 1, table 2). Then the remain- seem to be important.
ing variance in each of the later Goldberg scores was (b) A history of family and personal psychiatric his-
predicted from the five “blues” factor scores (heading tory was added to the linear model to see if the predic-
CATHERINE C. HAPGOOD, GAIL S. ELKIND & JAMES J. WRIGHT 303
Table 2. Prediction of Goldberg scores at 6,13,26 and 60 weeks postpartum from antenatal Goldberg score
and blues factor scores, as measured by F-ratios
tion of later depression was improved. However, these (c) Further tests were undertaken to test for inde-
two new variables accounted for very little of the pendence of “blues” factor scores from demographic
variance. The one exception was history of psychiatric variables. The relationship of maternity blues factor
disorder which by itself was a unique predictor for scores to other variables which might logically or
depression at fourteen months post partum (F = 4.28, theoretically be related to later depression was as-
p<O.OS) even when the S blues factors and family sessed, to check the independence of the factors per
psychiatric history were all co-varied out first. se. General linear models attempting to predict the fac-
tor scores from the following groups of independent
However, when two-way interactions were added to variables were used in this exercise: (1) Labour vari-
the above model then there was some improvement in ables, length of stages I and 11, type of anaesthetic, and
prediction. There were significant interactive effects type of delivery did not predict “blues” factors. (2)
between family psychiatric history, middle unhappiness, Planned pregnancy, previous abortion, pre-menstrual
and Goldberg scores at weeks 6, 13 and 60; between tension (PMT) whether or not breastfeeding at 6 weeks
family psychiatric history, late unhappiness and postnatally, number of feeds in 24 hours at 6 weeks
subsequent Goldberg scores; and between family postnatally and degree of difficulty breastfeeding at 6
psychiatric history, liability and Goldberg scores at weeks postnatally. None of these variables alone or in
weeks 13 and 60. None of these two-way interactions combination predicted “blues” factors with the single
was significant at more than two of the four time periods exception of middle unhappiness which was predicted
tested, however. by PMT alone (F = 4.08, p<O.OS).
304 MATERNITY BLUES AND POST PARTUM DEPRESSION
(3) Subject’s relationship with her own mother, with gested that the phenomena so loosely described as
respect to mother alive, mother in Auckland, “blues” are quite complex. The method used here,
childhood separation from mother, history of (rotation to orthogonality of principle component fac-
childhood physical abuse, closeness to mother, being tors, then naming the factors by their high weighted
like mother, dependence on mother, fondness of VAS components) enables us only approximately to
mother and ambivalent feelings about mother. None describe the independent subjective components, but
of the “blues” factors was predicted by the overall this appears a useful approximation.
model. However, ambivalent feelings about mothers, Firstly, while dysphoria is a necessary aspect of the
for the set of mothers of first babies only, predicted “blues” almost by definition, and has been widely
late unhappiness [F(I , 15)=4.84,p<O.O5] and early un- reported in the puerperium [2,7,10,19] the presence of
happiness [F(I , 15)=5.74, p<O.O5] uniquely, after all
Aust NZ J Psychiatry Downloaded from informahealthcare.com by University of Auckland on 01/13/15
Total scores on the Coldberg semi-structured psychiatric ment of “the blues” in the puerperium in the same way
interview were predicted by maternity blues factor scores as physical state is assessed, since this may be one of
at each time interval postpartum, including 14 months. the few predictors of the most common complication
Emotional lability was the most important predictor of of the postnatal period, postnatal deptession.
later psychiatric symptoms. Middle unhappiness was The results of this study together with those of Ken-
related to depression at 6 weeks post partum. An nerley confirm that the experience of “spirits going up
unexpected finding was a strong relationship between and down” is a critical phenomenon of “the blues”.
late unhappiness and depression at 14 months post Severe lability in the puerperium may be predictive of
partum. depression in later months. It is therefore essential to
The results of the analyses using extrinsic variables use a scale (or clinical evaluation) in which this chang-
ing mood is directly assessed, or the predominant fea-
Aust NZ J Psychiatry Downloaded from informahealthcare.com by University of Auckland on 01/13/15
13. Kennerley H, & Gath D. Maternity blues reassessed. Psychiatric the first three weeks after childbirth. Journal of Affective Disorders
Developments 1986;1: 1-17. I981 ;3:3 17-326.
14. Davidson J. Postpartum mood changes in Jamaican women: A 20. Goldberg D, Cooper B, Eastwood MR, Kedward HB, Shepherd M.
description and discussion of its significance. British Journal of A standardised psychiatric interview for use in community surveys.
Psychiatry 1972;12 1 :659-63. British Journal of Preventive Social Medicine 1970;24:18-23,
15. Nott PN, Franklin M, Armitage C, & Gelder MG. Hormone chan- 21. Kumar R, Robson KM. A prospective study of psychiatric disor-
ges and mood in the puerperium. British Journal of Psychiatry ders i n childbearing women. British Journal of Psychiatry
1976;128:379-83. 1984;144:35-47.
16. Handley SL, Dunn TL, Waldron S, & Baker JM. Tryptophan, cor- 22. Spitzer RL, Endicott J, & Robins E. Research Diagnostic Criteria:
tisol and puerperal mood. British Journal of Psychiatry rationale and reliability. Archives of General Psychiatry
1980;136:498-508. 1978:35:773-82.
17. Harris B. Prospective trial of I-tryptophan in the maternity blues. 23. Johnson R. A revision of socio-economic indices for New Zealand,
British Journal of Psychiatry 1980;137:233-235. Wellington. NZ Council for Educational Research.
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18. Paykel ES, Emms EM, Fletcher J. Rassaby ES. Life events and so- 24. Wainer H. Estimating coefficients in linear models: It don’t make
cial support in puerperal depression. British Journal of Psychiatry no never mind. Psychological Bulletin 1976;83:213- 17.
1980; 136339.346. 25. Hapgood CC. Paper presented to the Annual College Congress of
19. Kendell RE, McGuire RJ, Connor J, & Cox JL. Mood changes in the RANZCP, Auckland, May, 1987.
For personal use only.