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JPOR 432 No. of Pages 9

journal of prosthodontic research xxx (2017) xxx–xxx

Contents lists available at ScienceDirect

Journal of Prosthodontic Research


journal homepage: www.elsevier.com/locate/jpor

Original article

Three-dimensional evaluation of marginal and internal fit of


3D-printed interim restorations fabricated on different finish line
designs
Nawal Alharbia,b,* , Saud Alharbic , Vincent M.J.I. Cuijpersd, Reham B. Osmane,f ,
Daniel Wismeijerg
a
Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit
Amsterdam, Gustav Mahlerlaan 3004, 1081LA Amsterdam, Netherlands
b
Department of Prosthetic Dental Science, King Saud University, College of Dentistry, Riyadh, Saudi Arabia
c
Prince Sultan Military Medical City, Riyadh, Saudi Arabia
d
Department of Biomaterials, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
e
Removable Prosthodontics Department, Faculty of Dentistry, Cairo University, Egypt
f
Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije
Universiteit Amsterdam, The Netherlands
g
Department of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije
Universiteit Amsterdam, The Netherlands

A R T I C L E I N F O A B S T R A C T

Article history:
Received 15 February 2017 PurposeTo evaluate the influence of fabrication method and finish line design on marginal and internal fit
Received in revised form 10 July 2017 of full-coverage interim restorations.
Accepted 23 September 2017 MethodsFour typodont models of maxillary central-incisor were prepared for full-coverage
Available online xxx restorations. Four groups were defined; knife-edge (KE), chamfer (C), rounded-shoulder (RS),
rounded-shoulder with bevel (RSB). All preparations were digitally scanned. A total of 80 restorations
Keywords: were fabricated; 20 per group (SLA/3D-printed n = 10, milled n = 10). All restorations were positioned on
3D-SLA printing the master die and scanned using micro-computed tomography. The mean gaps were measured digitally
Finish line design
(ImageJ). The results were compared using MANOVA (a = .05).
Marginal and internal fit
ResultsInternal and marginal gaps were significantly influenced by fabrication method (P = .000) and
Micro-CT
Additive manufacturing finish-line design (P = .000). 3D-Printed restorations showed statistically significant lower mean gap
compared to milled restorations at all points (P = .000). The mean internal gap for 3D-printed restorations
were 66, 149, 130, 95 mm and for milled restorations were 89, 177, 185, 154 mm for KE, C, RS, RSB
respectively. The mean absolute marginal discrepancy in 3D-printed restorations were (30, 41, 30,
28 mm) and in milled restorations were (56, 54, 52, 38 mm) for KE, C, RS, RSB respectively.
ConclusionsThe fabrication methods showed more of an influence on the fit compared to the effect of
the finish-line design in both milled and printed restorations. SLA-printed interim restorations exhibit
lower marginal and internal gap than milled restorations. Nonetheless, for both techniques, all values
were within the reported values for CAD/CAM restorations.
Significance3D-printing can offer an alternative fabrication method comparable to those of milled
restorations.
© 2017 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

1. Introduction

In contemporary prosthodontics, interim restorations are used


as a transitional phase to evaluate the functional and esthetical
* Corresponding author at: Department of Oral Implantology and Prosthetic outcomes [1–4]. The restorations should offer adequate fit to
Dentistry, Academic Centre for Dentistry, Amsterdam (ACTA), University of
ensure mechanical stability and durability of the restoration and
Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan 3004, 1081 LA
Amsterdam, The Netherlands.
thus the health of the surrounding tissues [5,6]. Lack of adequate fit
E-mail address: nawalmurshed@gmail.com (N. Alharbi). can result in plaque accumulation, cement microleakage, marginal

https://doi.org/10.1016/j.jpor.2017.09.002
1883-1958/ © 2017 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
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discoloration, poor esthetics, teeth sensitivity, caries and peri- shoulder finish line designs and found the lowest absolute
odontal diseases [5]. Wide variation in the definition of adequate marginal discrepancy values with knife-edge design (87 mm)
fit and a clinically acceptable marginal gap exists in the literature compared to mini-chamfer (114 mm), chamfer (144 mm) and
and can be attributed to different study designs including different rounded shoulder (114 mm) finish line designs. Euán et al. [15]
restorative materials, examination method, finish line designs and found lower mean marginal gap values for Lava All-Ceramic
fabrication methods [7]. A recent systematic review on the fit of System with round shoulder finish-line design (52 mm) compared
CAD/CAM restorations fabricated from different materials reported to chamfer counterpart (64 mm). In contrast, Tsitrou et al. [16] and
an absolute marginal gap (AMG) of crowns to be in the range from Akbar et al. [17] revealed no significant difference in margnial gap
10–110 mm with the majority of values less than 80 mm. In the of dental restorations with shoulder and chamfer finish line
same context, the internal gap at axial part was 23–154 mm and at designs. The margin gap of CEREC 3 system composite resin crowns
occlusal part was 45–219 mm [8]. was 94 mm in chamfer finish line and 91 mm with shoulder finish
With the ongoing developments in the field of data acquisition line [16].
and manufacturing processes, digital technologies are gaining To the authors’ best knowledge, no previous study has
more acceptances. Additive manufacturing (AM) is being increas- evaluated the internal and marginal adaptation of 3D-printed
ingly applied in the field of prosthodontics. Dental restorations can directly fabricated restorations using the SLA technique with
be fabricated using resin based AM techniques both directly and different finish line designs. Therefore, the aim of this study was to
indirectly; stereolithography and or digital light processing (SLA/ evaluate the influence of fabrication method and finish line design
DLP) [2,4,9–13]. Both techniques use light/laser to cure a on the marginal and internal fit of full coverage interim dental
photosensitive liquid polymer layer by layer, following a specific restorations in two digital workflows (3D-printing versus milling).
path of the designed model. Our null hypothesis is that there is no difference in marginal and
Limited studies have evaluated the marginal and/or internal fit internal fit between 3D-printing and milled restorations in
of AM copings fabricated using SLA/DLP techniques. Kim et al. [10] different finish line designs.
found that the mean marginal gap of Co–Cr crowns was
significantly larger when fabricated indirectly using SLA technique 2. Materials and methods
(96 mm) compared to traditional, lost-wax fabrication method
(67 mm). The authors also reported an axial and an occlusal gap of 2.1. Study design
84 mm and 114 mm respectively for the indirectly manufactured
SLA crowns [10]. In contrast, Park et al. [2] found PMMA DLP- Four typodont models of maxillary central incisors were
fabricated implant restorations to have better marginal fit prepared to receive full coverage dental restorations; each with
compared to milled and conventionally fabricated counterparts a different finish line design. The four finish line designs were;
fabricated from PEEK and PMMA respectively. Nevertheless, the knife-edge (KE), chamfer (C), rounded shoulder (RS), rounded
authors found the fit of the three manufacturing methods to be shoulder with bevel (RSB). In both digital workflows, the prepared
within the clinically acceptable range. models were digitally scanned and then the data was exported as a
Munoz et al. [12] used DLP technique to fabricate wax patterns standard tessellation language (STL) format to a CAD software for
for indirect manufacturing of cast gold crowns and revealed that the design and the fabrication of full coverage restorations (n = 80).
the marginal gap was significantly larger for DLP fabricated For each finish line design, the restorations were fabricated using
patterns compared to the milled or manually fabricated wax 3D-printing (n = 10) and milling (n = 10) techniques. All restora-
patterns. tions were fitted on the master die without cementation and
In the same context, different finish line designs have been scanned using micro-computed tomography (Skyscan 1072,
shown to influence the marginal gap of the dental restorations. Bruker microCT, Kontich) [18]. The marginal and internal gaps
Comlekoglu et al. [14] compared the marginal gap of zirconia were measured using digital imaging processing software (ImageJ
crowns with knife-edge, mini-chamfer, chamfer and rounded 1.51; NIH). The flow of the study design is shown in Fig. 1.

Fig. 1. Flow of study design.

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
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2.2. Crown preparation

The models were prepared following the basic principles of


crown preparation [19]. All models were prepared with 2 mm
incisal reduction. Four finish lines designs were used; KE, 1 mm (C),
1 mm (RS) and 1 mm (RSB) [19]. All teeth were prepared with the
use of silicon index [20], together with the use of magnifying loupe
(30) for better visualization. The preparations were done using
diamond burs kit (LOT:22483; Horico) under continuous water-
cooling. The prepared models were scanned using desktop optical
scanner (Medit Identica BlueTM; Renishaw). The scanner was
calibrated following the manufacturer’s instructions. A thin layer
of anti-reflective powder coating was sprayed at a fixed distance of
20 cm for all the specimens to enhance the scanning procedure
(Helling 3D Scan Spray; Helling GmbH) [21,22]. The digital files
were exported in STL format, which were used for the design of
restorations.

2.3. Restorations design and CAD/CAM fabrication

The restorations were designed using 3-Shape Dental SystemTM


CAD solution version 2015. The design parameters were standard-
ized for all groups. A cement gap of 30 mm was defined [23]. Fig. 3. Slicing protocol for all scanned restorations.
Additional vertical space of 80 mm and a horizontal space of 30 mm
was added as recommended by an experienced dental technician. Bruker micro-CT, Kontich). A custom holder was fabricated to
One trained technician printed the restorations using stereo- standardize the position of the specimens during scanning and to
lithography-based 3D-printer (DW028D, DWS) in a hybrid ensure that the long axis of the tooth was perpendicular to the
composite resin material (Temporis1, shade A2, LOT: 040725; scanning beam. The specimen holder involves a transverse
DWS). The thickness of build layer was .05 mm and the maximum cylindrical hole, which allows the X-ray beam to pass through.
laser speed was 5000 mm/s [24]. The printed specimens were The specimen position was verified on the screen by a visible well
cleaned with 95% ethanol for one minute and post-cured using defined, sharp and clear circle formed when the X-ray beam pass
ultraviolet curing unit (S2; DWS) for 30 min as per the and run parallel to the transverse circular hole within the holder
manufacturer’s instructions [24]. The milled restorations were (Fig. 2). A scan resolution of 11 mm was defined for all specimens
fabricated using 5-axis milling machine (Wissner Ltd.; Germany) where the whole crown and coronal 1/3 of the root were included
in PMMA-based acrylate resin (Polycon1 ae; Straumann; shade A2) in one scan. Scans were recorded at X-ray source set to 100 kV and
with a bur diameter of 1 and 3 mm following manufacturer’s 98 mA, a 180 sample rotation and 10-frames averaging, a rotation
recommendation [25]. All specimens were then stored in a dry, step of .90 , an exposure time of 3.8 s and a 1 mm thick aluminum
lightproof box and tested within ten days of the manufacturing filter to optimize image contrast.
process. After scanning, a cone beam reconstruction was performed to
obtain 11 mm pixels, 2D-images with NRecon v.1.6.9.18 software.
2.4. Micro-CT scanning and analysis The ring artifact correction was set to 20 and beam hardening
correction to 4%. For the analysis, six slices were selected from each
Before scanning, all restorations were visually examined for any specimen; three in mesio-distal (MD) and three in labio-palatal
manufacturing defects, using optical magnification loupe 3.5. (LP) direction. The distance between each of the selected
Each restoration was manually placed on the master die without measuring points was 60 slices in LP and 110 slices in MD
cementation and without any manual adjustment [18]. The direction (Fig. 3). The slicing of the images was performed with
position of each crown was visually checked before scanning; CTanalyzer v.1.14 software. A total of 480 images were transferred
where the crown was stable without any rotation or displacement to Image processing software for analysis.
[18]. One blinded and trained examiner performed the measure-
The specimens were scanned using a commercially available ments of all images (n = 480) by using Image processing software
desktop X-ray micro-tomography system scanner (Skyscan 1072, (ImageJ 1.51; NIH). A second examiner was consulted for any

Fig. 2. Custom-made specimen holder with visible circle indicating that X-rays run parallel to the transverse hollow cylinder.

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
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Fig. 4. Internal and marginal fit measurement points on; (A) labio-palatal (LP) sections, (B) mesio-distal (MD) sections, (C) marginal fit measurement points on both (LP) and
(MD) sections.

difficulty encountered. Prior to each reading, the measurement The mean and standard deviation of the marginal and
tool was calibrated by measuring the pixel size; one pixel was equal internal gap of all specimens are shown in Tables 1 and 2.
to 11 mm. All measurements were taken under the magnification of The result of MANOVA was reported using Pillai’s trace
400. The internal and marginal fit was measured at several defined multivariate test as the assumption of homogeneity of vari-
points on MD and LP sections as shown in Fig. 4. The internal fit ance-covariance matrices was violated (Box’s M test, P = .000)
involves both the incisal gap and mid-axial gap measured at the [26]. The mean internal and marginal gap were significantly
middle of mid-axial wall. Further for better interpretation of the influenced by fabrication method (P = .000) and finish line design
results, the data of the incisal gap and mid-axial gap were reported (P = .000). Yet the influence of fabrication method was more as
separately. The marginal fit was reported by using the vertical gap shown by the Partial Eta squared value of (.96) compared to (.66)
(VG), horizontal gap (HG) and absolute marginal discrepancy (AMD). for finish line design. MANOVA showed statistically significant
Each point was measured three times and the average was used. For interaction effect between fabrication methods and finish line
each tooth, a total of 51 measurements (15 for internal fit and 36 for design, F (18,207) = 8.15, P = .000; Pillai’s trace = 1.245. Step-down
marginal fit) were collected as follows; on each BL slice: (2 mid- univariate analysis showed that the interaction between fabrica-
axial) + (1 incisal) + (2 VG) + (2 HG) + (2 AMD) = 9. Measurement on tion methods and finish line designs was statistically significant at
each MD slice: (2 mid-axial) + (2 VG) + (2 HG) + (2 AMD) = 8. Thus, the incisal, internal, mid-axial, VG and HG. On the contrary, at AMD,
total measurements per tooth: (9  3 slices) + (8  3 slices) = 51. the fabrication method showed similar effect in different finish
line designs (P = .133). The 3D-Printed restorations showed lower
2.5. Examiner calibration estimated mean marginal and internal gap values compared to
milled restorations. The difference was statistically significant at
Examiner calibration was done prior to the study. The blinded all points (P = .000). Amongst all points, the incisal gap was the
examiner (A.S) was calibrated against an experienced examiner (A. largest in both 3D-printed and milled restorations (Tables 1 and 2)
N). A total of 20 2D-images were used for the calibration procedure. (Fig. 5).
The internal and marginal gaps were measured on all 2D-images. MANOVA simple main effect showed that the mean internal
After 10 days, the gaps were re-measured. Intra-examiner and gap, mid-axial and AMD of 3D-printed restorations were
inter-examiner reliability were analyzed using interclass correla- significantly lower than that of milled restorations for all finish
tion (ICC). lines designs (P <.05). The difference at incisal gap was significant
in all finish lines except in KE design (P = .662), whereas for the HG
2.6. Statistical analysis the difference was significant in all finish line designs except in C
design (P = .219). The difference at VG was significant in all finish
The mean and standard deviations of internal and marginal lines except RSB design (P = .142).
gaps were analyzed using descriptive statistics. The data were The results of one-way ANOVA revealed that the mean internal
checked for normality distribution and equivalence of variances. gap and AMD were significantly different between different finish
The results were compared using multivariate analysis of variance line designs (P = .000) in 3D-printed restorations, whereas in
(MANOVA). A follow-up simple main effect test with Bonferroni milled restorations only mean internal gap was significantly
corrections was used to evaluate the difference between the different in different finish lines (Table 3). Tukey post hoc showed
fabrication methods in each finish line design (a = .05). One-way that in 3D-printed restorations the lowest mean internal gap was
ANOVA was used to analyze the influence of finish line design on in KE design, the difference between different finish lines was
the marginal and internal gap of the restorations in each statistically significant (P <.05) (Fig. 6A). Similarly, in milled
fabrication method separately. restorations the lowest mean internal gap was in KE design. The
difference was statistically significant (P = .000) between all
3. Results designs except S and C (P = .249). The lowest AMD for 3D-printed
restorations was with RSB design (Fig. 6B). The difference between
The intra-examiner reliability was .98 and the absolute the groups was not significant except for C design (P <.05).
agreement between the two examiners was .97 and thus Likewise, the lowest mean AMD in milled restorations was with
eliminating any possible measurement or examiner bias. RSB finish line (P >.05) (Fig. 7A and B).

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
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Table 1
Mean and standard deviation (SD) of internal gap (sum of incisal gap + mid-axial gap).

Fabrication methods Finish line Specimens number (N) Mean (mm) Standard deviation (SD)
Incisal gap 3D-printed KE 10 93 14
C 10 213 31
RS 10 210 6
RSB 10 161 15
Total 40 169 52
Milling KE 10 97 17
C 10 271 18
RS 10 259 19
RSB 10 208 11
Total 40 209 71
Total KE 20 95 15
C 20 242 38
RS 20 235 29
RSB 20 184 27
Total 80 189 65

Mid-axial gap 3D-printed KE 10 39 5


C 10 45 3
RS 10 51 4
RSB 10 29 2
Total 40 41 9
Milling KE 10 80 6
C 10 84 7
RS 10 111 9
RSB 10 99 7
Total 40 94 14
Total KE 20 59 22
C 20 64 20
RS 20 81 32
RSB 20 64 36
Total 80 67 29

Internal gap 3D-printed KE 10 66 8


C 10 149 15
RS 10 130 4
RSB 10 95 7
Total 40 110 33
Milling KE 10 89 8
C 10 177 10
RS 10 185 11
RSB 10 154 7
Total 40 151 39
Total KE 20 77 14
C 20 163 19
RS 20 158 29
RSB 20 124 31
Total 80 131 42

Knife edge (KE), chamfer (C), rounded shoulder (RS), rounded shoulder with bevel (RSB).

4. Discussion In the literature, several methods are reported to evaluate the


marginal and internal fit of the restorations [7]. In this study,
This in vitro study evaluated the effect of fabrication methods in micro-CT was used. This approach offers several advantages of
two digital workflows; 3D-printing versus milling and four finish being non-destructive, and allows for quantitative measurements
line designs (KE, C, RS, RSB) on the marginal and internal fit of full in three dimensions [18,28]. However, shortcoming of this method
coverage interim dental restorations. Based on the results, the null is the radiation artifacts resulting from the difference in coefficient
hypothesis that no difference exists in marginal and internal fit of radiation absorption among different materials [28]. A custom-
between 3D-printing and milled restorations in different finish line made holder was fabricated to standardize the position of the
designs was rejected. specimens during the scanning procedures. The maximum
In this study, only a maxillary central incisor model was magnification to visualize the complete crown resulted in pixel
evaluated to eliminate the influence of different tooth geometries size of 11 mm.
[27]. In addition, all restorations were analyzed without During the reslicing, the locations of the 2D-slices were selected
cementation, which is not a true representation of the actual so that the measurement points were widely distributed on the
clinical situation. Nonetheless, it has been shown that the use of tooth without any distortion of the image. (Fig. 3) The measure-
cement may lead to improper seating of the restoration and thus ments of the selected points on the 2D-slices allowed for 3D-
increases the marginal and internal gap [7]. Furthermore, the analysis of the fit of the restorations. Marginal fit was evaluated by
radiopaque nature of the cement may result in radiation artifacts measuring AMD, VG and HG to have an in-depth view of the
during the procedure of micro-CT scanning, an artifact that may marginal misfit of the restorations [29]. The number of measure-
impede the measurements of the internal and marginal gaps ment points for marginal gap was 36, which has been shown to
[18,28]. maintain the precision level of the measurements [7,28–30].

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
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Table 2
Mean and standard deviation (SD) of marginal gap.

Fabrication methods Finish line Specimens number (N) Mean (mm) Standard deviation (SD)
Vertical gap (VG) 3D-printed KE 10 16 10
C 10 25 6
RS 10 21 4
RSB 10 26 10
Total 40 22 8
Milling KE 10 39 21
C 10 40 5
RS 10 34 13
RSB 10 19 4
Total 40 33 15
Total KE 20 27 20
C 20 33 9
RS 20 27 12
RSB 20 23 8
Total 80 28 13

Horizontal gap (HG) 3D-printed KE 10 25 9


C 10 22 4
RS 10 20 3
RSB 10 25 4
Total 40 23 6
Milling KE 10 31 8
C 10 25 3
RS 10 41 8
RSB 10 33 4
Total 40 32 8
Total KE 20 28 9
C 20 23 4
RS 20 30 12
RSB 20 30 6
Total 80 28 8

Absolute marginal discrepancy (AMD) 3D-printed KE 10 30 10


C 10 41 5
RS 10 30 5
RSB 10 28 2
Total 40 32 8
Milling KE 10 56 25
C 10 54 5
RS 10 52 16
RSB 10 38 3
Total 40 50 16
Total KE 20 43 23
C 20 48 8
RS 20 41 5
RSB 20 33 6
Total 80 41 15

Knife edge (KE), chamfer (C), rounded shoulder (RS), rounded shoulder with bevel (RSB).

Internal fit was evaluated by measuring the incisal and mid-axial 1.5 and 1.8 for both the printed and milled restorations
gaps, yet data of the mid-axial and incisal gaps were reported respectively. This finding was different than the results of other
separately to provide details of the internal misfit of the reported studies. Kokubo et al. [34] reported an incisal gap of
restorations. The results were analyzed using MANOVA rather 170 mm, which is 3 to 4 larger than the programmed cement
than multiple two-way ANOVA’s to minimize the inflation of type I space. Other reports revealed an incisal gap and an occlusal gap
error [26,31]. that ranged from 110 to 204 mm, that was 5 to 6 more than the
The results showed that 3D-printed restorations exhibit programmed cement space [2,35–37]. The reason for the increased
significantly lower marginal and internal gap values than their incisal gap and whether it is related to incorporated spaces during
milled counterparts. The inferior marginal and internal fit of milled the design process still merits further investigation.
restorations may be attributed to errors resulting from the Several design parameters including programmed cement gaps
tolerance of milling burs [32,33]. Nevertheless, the mean AMG are proposed based on the required cement thickness and are
marginal gaps of both 3D-printed and milled restorations were mostly recommended based on operators’ and technicians’
within the reported values for the CAD/CAM restorations (10– experience and the available software [9,33,37]. The programmed
110 mm) [8]. cement thickness reported in literature varied from no gap [11], to
Among all measurement points, the largest gap in both 10 mm [3], till 15 mm with an additional vertical space of 65 mm
fabrication methods was found at the incisal part (169 mm for and a horizontal space of 50 mm [38], 30 mm [2,10,23], 50 mm [34],
3D-printing and 209 mm for milling). This finding was in 60 mm [1], till 85 mm [9]. Hoang et al. [9] evaluated the
accordance with previous studies [2,27,34–37]. In the present reproducibility of 25 mm, 45 mm, 65 mm, 85 mm and 105 mm
study, the measured incisal gap was 169 mm and 209 mm which cement gap of DLP 3D-printed resin copings and found that the
were greater than the programmed incisal cement space by 85 mm cement gap was the most reproducible [9]. In the same

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
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Fig. 5. Estimated mean of internal and marginal gap in 3D-printed and milled restorations.

context, the results of the current study revealed that the mid-axial dental restorations with controversial findings [14–17]. This can be
gap in 3D-printed restorations was 41 mm, which is lower than the viewed in the light of different experimental designs, different
programmed cement space (60 mm). Thus, it may be recom- material, fabrication and analysis methods.
mended that the programmed axial gap be increased to enhance The findings of this study revealed that in both fabrication
the marginal fit though this still requires to be confirmed with methods KE design has the least internal gap and RSB design
further studies (Fig. 6A and B). This lack of consistency between showed the least AMD. The difference in AMD between different
measured axial gaps and programed incorporated cement space finish line designs was not significant in milled restorations. In 3D-
may be due to an error occurring during the slicing procedure of printed restorations, the C design showed significantly larger AMD
the STL file. Such an error can minimize the accuracy of the fitting than the other finish line designs. This may be attributed to the
surface of printed restorations compared to the designed model. incremental layer pattern of build process in the 3D printing
On the contrary, the larger mid-axial gap of the milled restorations technology. The curved surface of the axio-gingival line angle in C
was attributed to errors from the tolerance of milling burs [32]. design may cause an increased stair-stepping error during the
Similarly, the incisal gap in KE design was lower than the slicing of the STL file. Therefore, the resultant increase in the values
programmed incisal space in both fabrication methods. Vertical of the AMD recorded with the C design in the printed group.
displacement of the restoration is unlikely to be the reason Although the results revealed that KE design exhibit the least
considering the values of the measured vertical gap (Table 1). internal gap in both fabrication methods, it cannot be recom-
The results of MANOVA showed that the finish line design is less mended for current clinical practice. KE design represents a very
influential on the marginal and internal fit of interim restorations conservative approach, which may limit the choice of restorative
compared to the fabrication method. Several studies evaluated the material. In addition, the visibility of KE finish line on digital or
influence of finish line design on marginal and internal fit of milled analogue model might not be optimal. Gingival bulk has been

Table 3
The influence of finish line designs on internal and AMD (mm) in both fabrication methods using One-way ANOVA.

Fabrication methods Sum of squares df Mean square F Significance


3D-printing Internal gap Between groups .040 3 .013 145 .000
Within groups .003 36 .000
Total .044 39
Absolute marginal discrepancy Between groups .001 3 .000 9.43 .000
Within groups .001 36 .000
Total .003 39

Milling Internal gap Between groups .057 3 .019 209 .000


Within groups .003 36 .000
Total .061 39
Absolute marginal discrepancy Between groups .002 3 .001 2.83 .052
Within groups .008 36 .000
Total .010 39

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
G Model
JPOR 432 No. of Pages 9

8 N. Alharbi et al. / journal of prosthodontic research xxx (2017) xxx–xxx

Fig. 6. Three dimensional reconstructed micro-CT image of the 3D-printed restoration in; (A) KE finish-line, (B) RSB finish-line.

Fig. 7. Influence of finish line design on internal fit and AMD in; (A) 3D-printing, (B) in milling. Different letters indicate statistical significance between different finish line
design.

reported in some cases with KE design due to insufficient room for designing of the restoration are also parameters that still need
the restorative material [14]. On the contrary, RSB design showed to be further assessed.
the lowest AMD values in both fabrication methods, as well as an
internal gap following the KE design (Fig. 6A and B). Improved 5. Conclusion
marginal adaptation associated with reduced AMD values com-
bined with acceptable internal fit values observed may be an Within the limitation of this in vitro study, fabrication methods
indication for recommending RSB design for SLA-3D printed showed more of an influence on the marginal and internal fit of
restorations. dental restorations compared to the effect of the design of the
However, generalizability of the results should be regarded finish line. Restorations fabricated using 3D-printing techniques
with caution. In this study, only one clinically available material exhibited lower marginal and internal gap than restorations
and one system for each fabrication method was applied. Whether fabricated using milling techniques. Nevertheless, in both fabrica-
the interpretation given for the findings of this study can be tion methods, all values were within the reported values for CAD/
applied to different materials and different systems still needs to CAM restorations.
be evaluated especially considering that such an interim restora-
tion would still be followed with a definitive restoration. In
addition, more studies are still needed to evaluate the influence of Acknowledgments
cementation procedure as well as the single versus multi-unit fixed
partial dentures. The optimal cement gap, extra vertical and The authors would like to thank DWS, Italy for supplying the
horizontal space values that should be incorporated during specimens used in this study. Additionally, the authors would like

Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002
G Model
JPOR 432 No. of Pages 9

N. Alharbi et al. / journal of prosthodontic research xxx (2017) xxx–xxx 9

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Please cite this article in press as: N. Alharbi, et al., Three-dimensional evaluation of marginal and internal fit of 3D-printed interim restorations
fabricated on different finish line designs, J Prosthodont Res (2017), https://doi.org/10.1016/j.jpor.2017.09.002

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