Title (English) Antibacterial activity of kakawate [Gliricidia sepium (Jacq.) Walp.

] leaves
against wound pathogens
Personal authors Gacusan, L.G.
Corporate authors Central Luzon State University
Publisher Central Luzon State UniversityScience City of Muñoz, Nueva Ecija
(Philippines)
Date of publication c2007
AGRIS Categories Plant structure
AGROVOC English terms Drug plants; Gliricidia sepium; Antimicrobial properties
AGROVOC French terms Plante medicinale; Gliricidia sepium; Propriete
antimicrobienne
AGROVOC Spanish terms Plantas medicinales; Gliricidia sepium; Propiedades
antimicrobianas
Language English
Notes Thesis (M.S. in Biology)
Abstract (English) The use of herbal medicine in the Philippine setting has been a part of
its rich culture and tradition. Even during the early times, Filipinos prepare medicines to
treat some illnesses out of the plants available in their backyards. An example of these
plants is Gliricidia sepiumH. B. Kakawate as it is commonly known has many folkloric
uses in the Philippines such as wound healing, skin itching or dermatitis. The
antibacterial activity of the ethanol extracts of Gliricidia sepium (Jacq.) Walp. was
evaluated against four bacterial wound pathogens (Staphylococcus aureus, Straptococci B
hemolytic, Pseudomonas aeruginosa, and Escherichia coli). This study was conducted so
as to test te antibacterial activity of kakawate leaf to bacteria that cause wound infection.
Specifically, this study aimed to determined the antibacterial activity of kakawate leaves
against the wound pathogens; compare the effectivity of kakawate leaf extract to gram
positive and gram negative bacteria that cause wound infection; and compare the
effectivity of kakawate leaf extract to commercially available antibacterial agent. Mature
kakawate leaves were collected in Gerona, Tarlac. The kakawate ethanol extract was
obtained by standard method. The antibacterial activity was found by using modified disc
diffusion method. The bacteria were obtained from the Nueva Ecija Doctors' Hospital and
Central Luzon Doctors' Hospital. Chloramphenicol (30 µg) was used as positive control
and distilled water as negative control. The ethanol extract of Gliricidia sepium (Jacq.)
Walp. was active against Staphylococcus aureus and Streptococci B hemolytic and did
not show antibacterial activity against Pseudomonas aeruginosa and Escherichia coli. The
antimicrobial activity of the kakawate extract is not comparable with that of the
antimicrobial activity of the chloramhenicol. This in vitro study substantiated the
antimicrobial activity of kakawate plants used in folkloric medicine. The plant extract
was effective against the two grain positive bacteria. However, they were ineffective
against Escherichia coli and Pseudomonas aeruginosa. Their medicinal use in infections
associated with these two species is not recommended. The antibacterial activity of the
plant extract is not as good as that of the positive control. This study also showed that
Gliricidia sepium (Jacq.) Walp. could be potential sources of new antimicrobial agents.
Type Thesis or Dissertation
http://agris.fao.org/agris-search/search/display.do?f=2008%2FPH%2FPH0810.xml
%3BPH2008C00039

Title (English) Antibacterial activity of kakawate [Gliricidia sepium (Jacq.) Walp.] leaves
against wound pathogens
Personal authors Gacusan, L.G.
Corporate authors Central Luzon State University
Publisher Central Luzon State UniversityScience City of Muñoz, Nueva Ecija
(Philippines)
Date of publication c2007
AGRIS Categories Plant structure
AGROVOC English terms Drug plants; Gliricidia sepium; Antimicrobial properties
AGROVOC French terms Plante medicinale; Gliricidia sepium; Propriete
antimicrobienne
AGROVOC Spanish terms Plantas medicinales; Gliricidia sepium; Propiedades
antimicrobianas
Language English
Notes Thesis (M.S. in Biology)
Abstract (English) The use of herbal medicine in the Philippine setting has been a part of
its rich culture and tradition. Even during the early times, Filipinos prepare medicines to
treat some illnesses out of the plants available in their backyards. An example of these
plants is Gliricidia sepiumH. B. Kakawate as it is commonly known has many folkloric
uses in the Philippines such as wound healing, skin itching or dermatitis. The
antibacterial activity of the ethanol extracts of Gliricidia sepium (Jacq.) Walp. was
evaluated against four bacterial wound pathogens (Staphylococcus aureus, Straptococci B
hemolytic, Pseudomonas aeruginosa, and Escherichia coli). This study was conducted so
as to test te antibacterial activity of kakawate leaf to bacteria that cause wound infection.
Specifically, this study aimed to determined the antibacterial activity of kakawate leaves
against the wound pathogens; compare the effectivity of kakawate leaf extract to gram
positive and gram negative bacteria that cause wound infection; and compare the
effectivity of kakawate leaf extract to commercially available antibacterial agent. Mature
kakawate leaves were collected in Gerona, Tarlac. The kakawate ethanol extract was
obtained by standard method. The antibacterial activity was found by using modified disc
diffusion method. The bacteria were obtained from the Nueva Ecija Doctors' Hospital and
Central Luzon Doctors' Hospital. Chloramphenicol (30 µg) was used as positive control
and distilled water as negative control. The ethanol extract of Gliricidia sepium (Jacq.)
Walp. was active against Staphylococcus aureus and Streptococci B hemolytic and did
not show antibacterial activity against Pseudomonas aeruginosa and Escherichia coli. The
antimicrobial activity of the kakawate extract is not comparable with that of the
antimicrobial activity of the chloramhenicol. This in vitro study substantiated the
antimicrobial activity of kakawate plants used in folkloric medicine. The plant extract
was effective against the two grain positive bacteria. However, they were ineffective
against Escherichia coli and Pseudomonas aeruginosa. Their medicinal use in infections
associated with these two species is not recommended. The antibacterial activity of the
plant extract is not as good as that of the positive control. This study also showed that
Gliricidia sepium (Jacq.) Walp. could be potential sources of new antimicrobial agents.
Type Thesis or Dissertation

http://agris.fao.org/agris-search/search/display.do?f=2008%2FPH%2FPH0810.xml
%3BPH2008C00039

Studies

Eczema Natural Cure Using Herbal Decoctions

1. Pandakaki-puti hot fot bath ( english name: )

o Boil 3 cups of chopped leaves in one gallon of water for 10 minutes. Add
2 gallons of hot water.
 Use this decoction for hot foot bath.
2. Kulitis hot compress ( english: Amaranth)
o Boil 3 cups of chopped fresh leaves in 5 glasses of water for 15 minutes.
Soak a small face towel in this decoction.
 Use compress directly on the eczema for 30 minutes.
3. Takip-kuhol poultice ( english: Indian hydocotyle)
o Chopped 10 leaves.
 Apply as poultice to affected area after the hot compress or hot
foot bath. Leave it on overnight.
4. Cacao or Kakaw seeds poultice ( english: Cocoa plant)
o Roast 10 seeds and pound.
 Apply as poultice to affected area after hot foot bath or hot
compress.

Copyright © 2009 Herbal-Med. All Rights Reserved.

http://herbal-med.co.cc/?cat=4&paged=3

CLINICAL FEATURES

• Scabies occurs in all populations. It is particularly prevalent in the developing

countries.
• Children younger than 15 years of age have the highest prevalence.
• After an incubation period of about 4 weeks the disease manifests itself with its
most characteristic symptom: severe itching with nocturnal exacerbation.
• The patient may present with extensive pyoderma or infective eczema.
• The pathognomonic lesion of scabies is the burrow: short, straight or curved,
slightly elevated lesion which often has a vesicle at its end .Burrows are typically
found on the finger webs, front of the wrists, axillae and genitalia.
 • Intensely itchy papular and vesicular lesions soon develop due to hypersensitivity
and these lesions may be generalized with predilections for the nipple and areola
in females, umbilical regions, buttocks, groins and thighs.
• The scalp, face and the palms and soles are usually spared sites in the usual
cases.
• The lesions are readily infected with bacteria and impetigo, folliculitis, oozing
and crusting are very commonly seen as also localized or extensive infective
eczema.

ATYPICAL FORMS

• Norwegian or crusted scabies: this is an unsually severe and extensive variety of

scabies that occurs in immunocompromised individuals ( HIV infection, steroid
therapy, malignancies), mentally retarded persons ( particularly Down’s
syndrome) , and in old debilitated persons unable to respond to the infestation by
scratching. Crusted scabies is characterized by thick scaling and crusted lesions
on the sites of preference of the mites. In contrast to the more usual variety of the
disease, the palms and soles may be affected and the nails may be thickened and
dystrophic. Facial involvement may also occur. The condition may give rise to a
generalized erythroderma. Thousand, even millions of mites may be present in a
patient.

• Nodular scabies: genital scabies in males may give rise to persistent papules and
nodules with lingers despite successful treatment of the infestation.
Histologically, the nodules may mimic a lymphoma.

• Bullous scabies: bullae may occur in infants and immunocompromised people.

• Animal scabies: is characterized by absence of burrows since the animal mites

cannot adapt themselves to human skin.

• Scabies in infants and in the very old: infantile scabies shows involvement of
palms and soles as well as the face and scalp. In the very old, the trunk may be
more severely infested.

• Scabies incognito: inadvertent application of topical steroid may modify the

clinical picture of scabies.

• Scabies in very clean individuals may show few lesions, thus confusion may
arise as to the true nature of the itch.

http://dermind.tripod.com/scabies.htm
 Posted in Ailments, Treatments | Tags: Ailments, Eczema, Home Remedy | No
Comments »

Diarrhea Natural Home Remedies – Herbal Treatment

for Diarrhea