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Recap
Action potential with voltage-gated Na+ channels and K+ channels
o All-or-nothing phenomenon
o Does not lose any energy when it runs down the length of axon
Oligodendrocytes create myelin sheath over axons—increases
transmission speed
Many forms of brain recordings with pros and cons
Ways of studying brain
o Past: case studies, brain lesioning, phrenology
o Now: neural imaging techniques (safe)
Exocytosis (anatomy of synapse)
o Dendrites collect IPSPs and EPSPs (inhibitory and excitatory)
MEGs “SQUIDs”
used to determine function of various parts of brain
looks at natural magnetic fields in brain
Learning and memorization
Hebbian Learning:
o When an axon of cell A is near enough to excite cell B and repeatedly takes part
in firing it, some growth occurs so A’s efficiency (as a cell firing B) is increased.
o When 2 neurons fire together they eventually wire together
o Memorization/learning are linked
Eric Kandel’s laboratory
o Showed involvement of Hebbian learning mechanisms at synapses in marine
Aplysia californica
o Induced learning via classical conditioning
Used electrical probe on sea slugs—retracted gills
They retracted gills even when no electricity
Glial cells
Form the myelin sheath
Hold the neurons in place, make up 10x amount of the brain as neurons
o Neurons make up 10% of the brain only
Types
o Oligodendrocytes make up 76% of glial cells
Provide insulation/myelin to neurons
Schwann cells are these but outside of CNS
o Astrocytes make up 17%
Star-shaped cells that provide physical/nutritional support for neurons
o Microglia make up 7%
Digest parts of dead neurons
Neurodegenerative diseases mainly from issues with glial
o Focus on microglia
Einstein had more glial cells and a larger corpus collosum and an enlargement of right
parietal region of brain (numerical and spatial processing)
Pop Psychology myths
We only use 10% of brian
We only use one side of brain (left/right brain)
Organization of the brain
We use contralateral language processing:
o Right hand motor movements left brain
Left visual field projected contralaterally to right, viceversa
Left brain: analytical/language/science math vs. right brain creativity, art/music etc
Split brain patients
o Looking at a point and seeing word on right field allows for identifying word
o Looking at word on left side of visual field cant say
Homunculus brain: face and hands have more sensitive neurons