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romeshsenewiratne@gmail.com
https://www.facebook.com/HUBForensics
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https://www.facebook.com/HolisticUniversityBrisbane
Charges:
1. Crimes Against Humanity (CAH)
2. Torture (mass)
3. Assault (mass)
4. False Imprisonment (mass)
5. Grievous Bodily Harm (mass)
6. Mass poisoning
7. Suicide Induction
8. Corruption
9. Accessory to Genocide
Mark Taylor
Particulars
1. Mark Taylor trained in the United Kingdom (UK) and is a psychiatrist who is currently
employed by the University of Queensland and Princess Alexandra Hospital.
2. Mark Taylor was previously employed by the Alfred Hospital in Melbourne, where in 2001 he
kept me prisoner and diagnosed me as having “schizophrenia/psychosis” with a previous
personality disorder (which he described as “paranoid” and “narcissistic”) citing my
allegation that the Australian Government and University of Melbourne (Burnet Institute)
were involved in the development and spread of HIV according to a covert racist eugenics
program (White Supremacist). At the time, and since then, he has not sought or read the
evidence I was able to provide at the time, on which my allegations were based.
3. My research and the evidence of the genocide I uncovered was completed as a thesis titled
“Eugenics and Genocide in the Modern World” in 2001, but Taylor refused to read it and I
was placed under other psychiatrists who also refused to read my work.
4. An edited version of the thesis (reduced from the original 600 pages to less than 300) was
published on Scribd as an e-book in 2010:
https://www.scribd.com/doc/71007453/Eugenics-and-Genocide-in-the-Modern-World-the-
cause-of-the-AIDS-epidemic-by-Dr-Romesh-Senewiratne-Alagaratnam-Arya-Chakravarti
5. In January 2016 Mark Taylor allowed me to leave the locked East Wing Ward of the Princess
Alexandra Hospital after I had been locked up for a week under the Nigerian psychiatrist
Jumoke “Jumi” Banjo, who had misdiagnosed me as having “schizophrenia”. He did not
interview me and did not recognise me from 2001. I recognised him instantly.
6. In 2018 I received a phone call from Raghavan Raman (case manager qualified as a
psychiatric nurse at Griffith University in 2009). Raman said that the appointment that I had
been given with the Pakistani psychiatrist Ghazala Watt for the next day had been cancelled
and that I would instead be seeing Mark Taylor.
7. I attended the appointment with Mark Taylor at the Woollongabba Community Health
Centre on Wednesday 9 May 2018.
8. I told Mark Taylor who is now a professor at the University of Queensland, where I
graduated in Medicine in 1983, that the notes the hospital was relying on were factually
inaccurate and could not be relied on. He said “that wouldn’t surprise me”.
9. He then asked me questions and entered my answers while looking at the computer screen
and not me. I answered his questions honestly, but was disturbed by his line of questioning.
The questions he asked were dictated by what information was requested by the computer
program he was using – about my alcohol and drug consumption, family history of mental
illness and previous diagnoses. He claimed not to remember me from 17 years ago and I told
him “You obviously made a greater impression on me than I did on you”.
10. After about half an hour, Taylor said the time for the consultation was up, that he was happy
by how I was going and said he would see me in three months’ time.
11. I asked him if he thought I had schizophrenia.
12. He said “I think you were psychotic in the past but you aren’t now”.
13. I told him that the injection that was being forced on me was stopping me from ejaculating
and he expressed surprise, though this adverse effect is described in the drug companies
literature. I also told him that the drug was causing me to dribble due to hypersalivation,
made me gain a lot of weight and was sedating me and dulling my creativity and musicality,
causing anhedonia (lack of pleasure, a recognised adverse effect of the class of drugs to
which Paliperidone belongs).
14. I also told him that the drugs used to treat schizophrenia shortened patients’ lives, but he
disputed this, saying that studies showed the best survival of diagnosed “schizophrenics”
was when they were treated with Clozapine (Clozaril). I disagreed but didn’t argue with him.
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15. I asked him if he would stop or at least reduce the drug and he said he would think about it.
16. When I phoned him two weeks later and stressed the adverse effects I was having from the
Paliperidone, he told me he would have to check with the case manager (Raghavan Raman)
before reducing the drug.
17. A week later I was contacted by Raghavan Raman saying that the injection would be kept at
the high dose of 100 mg despite the adverse effects I am suffering from.
18. I asked Raman to make an urgent appointment to see Taylor, due to the dribbling and
hypersalivation I am suffering from.
19. The appointment was made for two weeks later but was cancelled again. A new
appointment has been scheduled for a week’s time.
17.7.2018
https://www.youtube.com/HolisticUniversity
20.
https://www.researchgate.net/publication/318799840_A_stitch_in_time_3-monthly_long-
acting_injectable_paliperidone_palmitate_in_schizophrenia
schizophrenia
Correspondence to:
Mark Taylor
University of Queensland,
marktaylor2@nhs.net
UK
editorial2017
Editorial
Table 1. Summary of the pros and cons of LAIs versus oral medications.
232 journals.sagepub.com/home/tpp
Depot antipsychotic medication, often referred to as long-acting injections (LAIs), are an important
treatment option for mental health problems such as schizophrenia and bipolar disorder.1,2
They were designed over 50 years ago to promote adherence to maintenance antipsychotic
medication, but arguably remain stigmatized and underused.3 Table 1 compares oral formulations
with LAIs.
International guidelines recommend LAIs for both patients with demonstrated poor medication
adherence and those who prefer an LAI.1,2 Both an independent long-term comparative trial by
Subotnik et al.4 and a systematic review by Taylor and Ng5 have highlighted the value of earlier use
of LAI preparations in psychosis, reporting decreased relapse rates through improved medication
adherence, which reduces the risk of toxic relapse and possible subsequent rehospitalisation.4–6
This begs the question, would a cardiologist wait till the second or third heart attack before
instituting the most effective treatment?6
Antipsychotic medication development has stagnated over recent years, so the introduction of the
first 3-monthly or quarterly LAI antipsychotic deserves review.
Paliperidone palmitate is a benzisoxazole derivative, and the 3-monthly variant (PP3; also known as
INVEGA TRINZA®) is available in prefilled syringes that require vigorous shaking, unlike many other
LAIs or depots. The transport substrate of PP3 has been modified to increase its elimination half-life,
which allow dosing at 3-monthly intervals. PP3 is the first and only currently available quarterly
injectable, and as such, represents a significant advance in the maintenance treatment of
schizophrenia.
PP3 is available in four strengths (175 mg, 263 mg, 350 mg, and 525 mg), which are equivalent to the
original monthly paliperidone LAI strengths of 50 mg, 75 mg, 100 mg, and 150 mg, respectively.
Formulation of PP3 equivalent to a paliperidone monthly dose of 25 mg is not yet available. There is
a 2-week window for administration of PP3.
Importantly, PP3 is only recommended after stability on monthly paliperidone for a minimum of 4
months, where the last two monthly doses are required to be stable prior to switching. PP3 has an
elimination half-life of approximately 85–95 days (when administered as a deltoid injec-
tion), and 118–139 days (when administered as a gluteal injection). PP3 would likely remain in the
body for a period of 340–695 days, depending on injection site, dose, and individual patient pharma-
cokinetic factors.
The two approval trials for PP3 were both sponsored by the manufacturer. The first trial
demonstrated efficacy compared with placebo for prevention of schizophrenia relapse, and
involved 379 participants who each received a single dose of PP3, with 145 individuals then
receiving placebo and 160 receiving at least one further dose of PP3. The second trial was a
long-term double-blind non-inferiority study, which recruited 1429 participants. All of them
were treated with monthly paliperidone palmitate before 512 people were then randomly
assigned to continue monthly paliperidone, and 504 were randomly assigned to switch to
PP3, with a 48-week continuation phase. Relapse rates over that period were not
significantly different between PP3 (8%) and monthly paliperidone (9%) arms in this study.
No other studies of PP3 are yet in the public domain.
Given that PP3 contains the same active molecule as monthly paliperidone, it has the same
potential adverse effects,7,8 including prolactin elevation; weight gain; and, less frequently,
sedation and extra-pyramidal symptoms. Key differences between PP3 and monthly
paliperidone are the requirement for vigorous shaking of the vial for 15 seconds to ensure
uniform dosing, as well as the increased volume of injection, with the highest PP3 dose (525
mg) being administered over a 2.6 ml injection. Despite the increase in volume of injection,
the non-inferiority study established comparable tolerability between preparations, without
significant increases in local injection site reactions. Dealing with emergent adverse effects
with a 3-monthly preparation could be intrinsically challenging, although stabilization on the
monthly preparation before-hand should reassure clinicians as to the patient’s ability to
tolerate PP3.
Current experience
The authors’ experience (admittedly limited to 12 cases) of switching to PP3 has revealed
that no patients have so far declined to switch, with all indicating a preference for the less
frequent 3-monthly injections. Patients are reassured that the therapeutic molecule is the
same, with a very similar efficacy and tolerability profile, it is simply a ‘slower release’
variant of paliperidone LAI.
There have also been no significant new adverse effects compared with monthly
paliperidone, with a global impression of similar local injection site reactions and pain.
One anticipated concern with it is that the decrease in frequency of injection may result in
decreased patient contact and care. Although the intramuscular administration of PP3 is 3
monthly or ‘seasonal’, that does not mean the frequency of concomitant psychosocial
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A related concern might be that PP3 facilitates transition away from expert mental health
care providers to primary care, where the multidisciplinary holistic therapy may not be
available. As always, clinical needs should be assessed on a case-by-case basis, and not be
dictated by political or financial constraints.
Clinicians administering PP3 have at times commented that it is more difficult to be aware
of when the next LAI dose is due, resulting in medication charts being checked repeatedly.
PP3 does offer a 2-week window for administration, easing this burden and accommodating
weekends and staff time off.
Looking ahead
With current evidence indicating treatment with antipsychotic medication for at least 18
months following a first episode of psychosis,2 and studies demonstrating poor medication
adherence in this specific population,6 the prospect of a slower-release antipsychotic LAI is
a step forward. Use of a 3-monthly depot early in the schizophrenia disease course would,
however, represent a paradigm shift. Nevertheless, it is noted that 3 monthly (and longer-
acting implantable) contraceptives are widely sought after by the general public.
Patient choice and autonomy need to be upheld, but patients also deserve access to
appropriate evidence-based medication from the outset of their diagnosis, including
information on the benefits of antipsychotic medication; the risks of early cessation or poor
adherence with antipsychotic medication; and available preparations including oral and LAI
antipsychotics. There is evidence that some psychiatrists themselves view LAIs or depot as
stigmatizing or too coercive, and perhaps unconsciously filter out this potential therapeutic
option.9 This is despite a national study indicating the same antipsychotic molecule in LAI
journals.sagepub.com/home/tpp 233
formulation reduced relapse rate by 64% compared with the identical oral molecule.6
The unveiling of PP3 serves as a timely reminder that antipsychotic LAIs have a role across
the disease pathway in schizophrenia. Given the evidence noted above, it could be argued
that mental health clinicians should be justifying why they are not using clozapine or an LAI
in established schizophrenia.
Funding
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This research received no specific grant from any funding agency in the public, commercial,
or not-for-profit sectors.
Mark Taylor has accepted fees and hospitality from Janssen, the manufacturer of PP3. HH
has nil to declare.
References
1. Gelletly C, Castle D, Dark F, et al. Royal Australian and New Zealand college of
psychiatrists clinical practice guidelines for the management of schizophrenia and related
disorders. Aust N Z J Psychiatry 2016; 50: 32–36.
3. Patel MX, Taylor M and David AS. Antipsychotic long-acting injections: mind the gap. Br J
Psychiatry. 2009; 195: S1–S4.
4. Subotnik KL, Casaus LR, Ventura J, et al. Long-acting injectable risperidone for relapse
6. Tiihonen J, Haukka J, Taylor M, et al. A nationwide cohort study of oral and depot
603–609.
8. Young SL, Taylor M and Lawrie SM. “First do no harm.” A systematic review of the
prevalence and management of antipsychotic adverse effects. J Psychopharmacol (Oxford,
England). 2015; 29: 353–362.
9. Waddell L and Taylor M. Attitudes of patients and mental health staff to antipsychotic
long-acting injections: systematic review.
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Objectives: The aim of this study is to provide an opinion paper reviewing the role of depot or long-
acting injectable (LAI) antipsychotic medications, with comments on individual newer LAIs such
aripiprazole maintena and paliperidone palmitate. In particular, we share our recent experience of
using paliperidone three-monthly LAI. We also reflect on the associated benefits and potential
harms of LAIs, and when they may be used. Conclusions: LAI antipsychotics are an important and
arguably under-utilised therapeutic option, particularly where medication adherence is a priority,
and where an informed patient opts for this formulation. Paliperidone is the first three-monthly LAI
antipsychotic, and as such represents a significant advance in the range of treatment choices.
(PDF) Going the distance: reviewing.... Available from:
https://www.researchgate.net/publication/323271189_Going_the_distance_reviewing_antipsychoti
c_depot_or_long-acting_injectable_treatments_in_Australasia [accessed Jul 17 2018].
Download – First do no harm. ” A systematic review of the prevalence and management of antipsychotic adverse effects”
Transcript
What is the relationship between treatment adherence and
antipsychotic side effects?
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Sometimes, you have people for example doing well on olanzapine. I’ve
got a few patients at the moment who are doing well on olanzapine but
you worry about the metabolic consequences. So there are clearly some
lifestyle interventions that are crucial here. For example, I always
prescribe a 45- to 60-minute walk a day. I require my patients to go
walking every day.
Another related issue is the diet. The diet is difficult here in the UK. The
best diet as far as I’ve understood is the so-called Mediterranean diet.
Having said that, getting some people with schizophrenia over to a more
healthy diet is a big challenge. We have a colleague in Scotland called
Robin McCravey who switched people over to a healthy diet for six
months. He gave them free vegetables and fruits and what have you for
six months to try and change their dietary habits. They did change with
dietitian advice during that period of the study. But then at the end of the
study when the free food stopped, they just moved back to the fried food
or the junk food.
I would plug off Scottish Guidelines, SIGN 131.
What about the pharmacological management? Do you have any
suggestions?
What I specifically mentioned is use of metformin. I started using that
with clozapine and olanzapine sometimes particularly in younger
individuals. Some clinicians (not me) even use metformin
prophylactically if they feel that clozapine or olanzapine are a good idea.
The dosing is 500 mg or 1 gr of slow-release metformin. Metformin is a
very safe medicine. The diabetologists like it, it improves insulin
sensitivity. It doesn’t send you into a hypo. It’s a very safe medication.
You probably wouldn’t want to take it if you got irritable bowel syndrome.
But aside from that, it’s quite an easy to use medication. So I have been
using metformin a lot more frequently.
The other thing that I’d pass on to your colleagues which they probably
know already is low-dose aripiprazole, 5 mg, possibly 10 mg of going
alongside as a side order to the olanzapine and clozapine. Not really for
its antipsychotic effect but for its corrective metabolic effect.
Those are a couple of medication strategies that I’ve certainly been
using in the last couple of years to go along – don’t get me wrong, to go
alongside the lifestyle and dietary interventions because what we see
from the diabetes world is that if you combine the lifestyle and the
dietary with the medication, that’s when you get the best results.
You are one of the authors of the Glasgow Antipsychotic Side-
effect Scale. What can you tell us about it?
When we looked at it, the default scale in the UK was one called
LUNSERS, Liverpool University Side Effect Rating Scale, which came
out in 1993 which was a long time ago before most of the newer drugs.
The LUNSERS didn’t really have many of the metabolic questions that
we wondered. It was also quite long, three and a bit pages. So we just
thought we could do better than that.
We validated the GASS, the Glasgow Antipsychotic Side-effect Scale. I
think it seems to have taken off partly because it’s quite short and partly
because the language is quite user friendly. We spent a bit of time
converting difficult words like galactorrhea into plain English. And maybe
partly because it’s free, you don’t have to pay anyone, you can use it if
you like it.
The only thing we copyrighted is the intellectual property, Linda and I. So
if you want to use it and distribute it, please feel free to go ahead.
Certainly in the UK and to some extent Australia, it seems to be the
default scale if you’re going to use a scale for side effects.
Are there any final comments you would like to share?
What I would say is let’s try to be evidence based. Let’s think carefully
about what we would like for ourselves and do onto others as we’d have
done to ourselves. But let’s pay attention to the latest literature and the
latest guidelines, the best guidelines. Clearly, over the last decades,
there hasn’t really been a breakthrough in the treatment of schizophrenia
which is a little bit sad. I know the industry is retrenched or retracted in
some ways from these difficult complex mental illnesses but it’s our duty.
These are common problems and it’s our duty to keep working away,
helping people to the best of our ability.
I think most psychiatrists are not just interested in medications. I’m
particularly interested like many other people, but we went into
psychiatry to look at other treatment modalities whether it’s
psychological therapies, whether it’s lifestyle interventions or whether it’s
family interventions. These are all crucial parts of delivering psychiatric
treatment.
I like to emphasize that medications are clearly crucial and important but
it’s one piece of the jigsaw.
Published in: Antipsychotics, Antipsychotics - Featured articles, Second-
generation antipsychotics
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Presence of psychosis
If the main reason for SIDMA is presence of psychosis, how
do these psychotic symptoms affect the individual’s
decision-making ability? Consider this example where the
medical practitioner has stated the presence of delusions for
justifying SIDMA: ‘He adamantly rejects the notion that he
is unwell . . . He is deluded regarding treatment, believing
that I am trying to kill him rather than treat his psychosis’.
In this statement, the medical practitioner has stated that
the patient’s delusions impair his decision-making ability
about treatment as he firmly believes the psychiatrist is
trying to kill him. Hence the patient has poor judgement
about treatment because his delusions mean that he cannot
interact appropriately with the psychiatrist.
Another well-documented statement justifying the
presence of psychosis for SIDMA was:
‘at present displays a significant disordered thought process
with delusional beliefs. . .When trying to talk to her she
appears unable to focus on a subject being quite incoherent in
her thinking and flighty in her thoughts’.
Less well-documented reports included: ‘I have observed
[X’s] behaviour over some months and her thoughts are
impaired’. In this report there is lack of clarity about how
the individual’s impaired thinking has an impact on SIDMA.
Other reasons for SIDMA (severe depressive
symptoms and learning disability)
In the following example, the psychiatrist has described the
patient’s symptoms and how this has an impact on her
decision-making ability with regard to medical treatment.
‘. . . She demonstrated numerous cognitive distortions which
are typically found in severe depressive illness. She views the
future as hopeless and views all interventions as being futile.
As such, she is unable to appraise information provided to her
with respect to the provision of medical treatment’.
The psychiatrist in the following report has stated that it’s
the individual’s learning disability that limits her ability to
understand the assessment and treatments and nothing
ORIGINAL PAPERS
Shek
et al
Understanding ‘significant impaired decision-making ability’
241
more. There are no details of which particular aspects of the
person’s learning disability affects SIDMA:
‘ability to understand the purpose of her assessment and
treatment and make decisions about what is proposed for her
assessment and treatment is limited by her learning disability’.
Implications and recommendat ions
It is necessary for the medical practitioner to justify clearly
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How schizophrenia
impacts people's lives
Schizophrenia is a chronic, serious and often severely disabling
brain disorder that affects approximately 1 in 100 American
adults (about 2.4 million people) in the United States.1 It is
characterized by symptoms such as hallucinations, delusions,
disorganized thinking, lack of emotion and lack of energy, as
well as problems with memory, attention and the ability to plan,
organize and make decisions.2
https://www.youtube.com/watch?v=v7AFtMgs6bU
2SHARE
Chrys Muirhead
SUBSCRIBED 19
Dr Mark Taylor speaking at the Royal College of Psychiatrists in Scotland Winter Meeting on 29
January 2016 in Glasgow. http://www.rcpsych.ac.uk/workinpsychi... Dr Taylor said: "you are either
abstinent or promiscuous when it comes to industry (financial links with pharmaceutical companies).
Well you can see which side I fall on ..." Dr Taylor is Chair of SIGN 131 Guideline: Management of
Schizophrenia: http://www.sign.ac.uk/guidelines/full...
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"Abstinent or promiscuous when it comes to industry (drug companies). You can see which side I
fall". An admission of corruption.
REPLY
REPLY
3. He disparages the concerns of other psychiatrists that LAI's are too coercive and have
unacceptable adverse effects.
4. Rather than stopping the drugs when they cause adverse effects, he has developed a "rating
scale" to measure them and recommends other drugs to counter the known adverse effects of
"antipsychotic" drugs.
7. He routinely judges people to have "impaired decision-making ability" and “lack of insight”
if they disagree with his diagnoses and treatments and has written about this, promoting the
term "SIDMA" among his human rights-abusing, drug-pushing colleagues. SIDMA stands
for "significant impaired decision-making ability".
8. He has promoted and trialled, on his patients, a new 3-monthly Paliperidone depot
injection called "PP3" and has written papers saying how wonderful it is, recommending it
for first episode psychosis.
9. He recommends that people be kept on these drugs for 18 months after a first admission for
"psychosis" and 5 years for subsequent admissions. This is HIGHLY abusive. Drugs should
be used for the least time necessary at the lowest dose that works - attention should always be
paid to adverse effects with a constant evaluation about whether the drug is still necessary.
10. He sees numerous patients every day and charges Medicare for poisoning them with
drugs he is paid by the drug companies to promote.
11. He has co-authored a paper promoting these depot injections with Dr Balaji Motamarri
who is the Director of the MSAHMS (Metro South Addiction and Mental Health Services,
which includes the PA Hospital). Balaji Motamarri has also received "fees and hospitality
from Janssen (and other drug companies)
12. Each of the injections costs the taxpayer between $400 and $600 and they have the effect
of shortening patients' lives and causing a wide range of adverse effects which he is fully
aware of and has developed a "rating scale" to measure (called GASS - Glasgow Adverse-
effect Symptom Scale) for which he claims intellectual copyright.
13. When patients have sexual problems from the drugs (which he says is reported by 50% of
his patients) rather than stopping the drug he recommends that they take Viagra.
14. He recommends that patients on these drugs also take anti-diabetic drugs (hypoglycaemic
agents) to take away the risk of diabetes from these drugs, though there is no evidence that
this works.
Impression:
1. Some people do medicine to heal people; Mark Taylor did medicine to make money.
2. He admits to accepting bribes from the Belgian drug giant Janssen-Cilag and other drug
companies.
3. His co-authors include other drug company stooges.
4. He is cruelly studying the “adverse effects” of drugs that should be banned for shortening
patients’ lives and causing a wide range of distressing symptoms including akathesia,
galactorrhoea, lethargy and somnolence, cardiac arrhythmias and heart attacks, obesity,
diabetes, sexual dysfunction, movement disorders and metabolic disorders – Taylor knows
this and has developed a “rating scale” to “measure” the “adverse effects” (GASS) for which
he has maintained “intellectual copyright”.
5. Rather than stopping the toxic drugs when adverse effects develop he recommends that
additional, expensive drugs be taken in addition (example Viagra for sexual dysfunction) and
hypoglycaemic agents as a “prevention” for diabetes from the drugs he is promoting.
6. He is grossly negligent and dangerous to the public and the medical profession.
7. He is extremely corrupt.
8. He routinely gets people locked up in the public hospital system in Scotland and Australia if
they refuse to take the drugs he orders and refute the poorly considered mental illness
labels he puts on them.
9. He is articulate and actively promoting the schizophrenia label as well as newer jargon like
‘SIDMA’ that can only be understood by people initiated into the British psychiatric system.
10. He is not capable of being a psychiatrist in Scotland and Brisbane at the same time. It is one
reason that he neglects his public patients who are of value to him only as experimental
subjects.
11. He is arrogant in his extremist opinion.
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