Obesity:

http://www.who.int/mediacentre/factsheets/fs311/en/ - WHO fact file on obesity.

https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/613532/ob
es-phys-acti-diet-eng-2017-rep.pdf - UK obesity
https://www.niddk.nih.gov/health-information/health-statistics/overweight-obesity
- US obesity
https://stateofobesity.org/obesity-rates-trends-overview/ - US obesity
https://sencanada.ca/content/sen/committee/421/SOCI/Reports/2016-02-
25_Revised_report_Obesity_in_Canada_e.pdf - Canada obesity
https://www.sciencedirect.com/science/article/pii/S0002934396004561 - reduced fat
and calories = fat
https://ac.els-cdn.com/S0899900715000775/1-s2.0-S0899900715000775-main.pdf?
_tid=8fc6ea52-3336-460e-9890-
b39669fa78fd&acdnat=1521637386_3f081c4a6c61cec2efad427ff9872bfa - weight gain
due to increased carbs, not eating too much fat.

Diabetes:
https://www.indexmundi.com/facts/indicators/SH.STA.DIAB.ZS/rankings -
Diabetes levels globally
https://www.cdc.gov/diabetes/statistics/slides/long_term_trends.pdf -
Diabetes US
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325029/ - patients coming off of
medication after being on a KD
https://www.ncbi.nlm.nih.gov/pubmed/17447017 - long term keto is safe for
diabetics
https://jamanetwork.com/journals/jama/fullarticle/2434682 - 49-52% of the
population estimated to have diabetes or prediabetes
http://diabetes.diabetesjournals.org/content/58/5/1237 - improvements in
cognition in Type 1 diabetes, taking ketones

Weight Loss:
https://www.cambridge.org/core/journals/british-journal-of-
nutrition/article/effects-of-low-carbohydrate-diets-v-low-fat-diets-on-body-weight-
and-cardiovascular-risk-factors-a-meta-analysis-of-randomised-controlled-
trials/B8FBAC51C156D8CAB189CF0B14FB2A46 - LC more weight loss, higher LDL
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139817 - LC
better
https://www.cambridge.org/core/journals/british-journal-of-
nutrition/article/verylowcarbohydrate-ketogenic-diet-v-lowfat-diet-for-longterm-
weight-loss-a-metaanalysis-of-randomised-controlled-
trials/6FD9F975BAFF1D46F84C8BA9CE860783 - LC > LF
https://www.narcis.nl/publication/RecordID/oai%3Acris.maastrichtuniversity.nl
%3Apublications%2F3b82f4d9-158d-440a-b1c7-5bb319f872ba - obesity doesn't impair
weight loss at a cellular level
http://www.mdpi.com/2072-6643/5/12/5205 - targets lost weight and didn't regain
it.
https://www.researchgate.net/publication/51511582_Effects_of_a_moderate_low-
carbohydrate_diet_on_preferential_abdominal_fat_loss_and_cardiovascular_risk_factor
s_in_patients_with_type_2_diabetes - visceral fat loss on LC
http://onlinelibrary.wiley.com/doi/10.1038/oby.2009.460/full - LC lost more
weight, LF reduced calories more but still lost less on average.
https://www.pubfacts.com/detail/20101008/A-randomized-trial-of-a-low-carbohydrate-
diet-vs-orlistat-plus-a-low-fat-diet-for-weight-loss - LC as effective as
LF + weight loss drugs.
https://archive.org/stream/9213277.nlm.nih.gov/9213277#page/n0/mode/2up
- Letter on Corpulance, William Banting
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100652 - No
difference in weight loss on keto (the paper Zoe Harcome rips apart)
https://www.ncbi.nlm.nih.gov/pubmed/17341711 - low-carb most effective diet
https://www.nytimes.com/2016/09/11/opinion/sunday/before-you-spend-26000-on-weight-
loss-surgery-do-this.html - Don't do surgery, do this
https://www.researchgate.net/publication/308338265_Short-
Term_safety_tolerability_and_efficacy_of_a_very_low-calorie-
ketogenic_diet_interventional_weight_loss_program_versus_hypocaloric_diet_in_patien
ts_with_type_2_diabetes_mellitus - keto more effective + glycaemic control
http://www.samj.org.za/index.php/samj/article/view/7302/5506 - serious
weight loss + meds not needed for some people, better weight loss than on iso-
caloric high-carb diet
https://www.hsph.harvard.edu/news/press-releases/low-fat-diet-not-most-effective-
in-long-term-weight-loss/ - low fat not most effective (harvard)
https://www.ncbi.nlm.nih.gov/pubmed/26527511 - high fat = more weight loss
than low
https://www.readbyqxmd.com/read/23155696/metabolic-impact-of-a-ketogenic-diet-
compared-to-a-hypocaloric-diet-in-obese-children-and-adolescents - better than
hypocalorix in children
https://archive.org/details/naturalfoodofman00densrich - weight loss by
cutting out starches, 1890
https://www.reuters.com/article/us-dieting/dieters-put-on-weight-in-the-long-run-
study-idUSN3036700020070402 - dieters put on more weight in the long run.
http://www.normanmarcuspaininstitute.com/wp-content/uploads/2014/09/Effects-of-Low-
Carbohydrate-and-Low-Fat-Diets.pdf - greater weight loss on LC, more muscle
loss from high carb.

Glycaemic Control:
https://academic.oup.com/ajcn/article/97/3/505/4571510 - LC 2nd best after
Medditeranean.
http://diabetes.jmir.org/2017/1/e5/ - LC effective for decreasing TIIDM medication
https://www.ncbi.nlm.nih.gov/pubmed/25828624 - improvements on Paleo diet
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063858/ - LC normalises glucose
https://www.ncbi.nlm.nih.gov/pubmed/24717684 - better improvemenst on LC also
more weight loss.
https://www.jstage.jst.go.jp/article/internalmedicine/53/1/53_53.0861/_article
- LC works as alternative to calorie control for GC.
https://www.sciencedirect.com/science/article/pii/S0899900712000731 - keto more
effective than simple low calorie at lowering GC
http://www.scielo.org.za/scielo.php?pid=S0256-
95742016000800016&script=sci_arttext&tlng=es - Noakes, lifestyle
intervention in Canada
https://www.abqjournal.com/1144853/lowcarb-diet-fights-diabetes.html - low
carb fights diabetes
https://www.ncbi.nlm.nih.gov/pubmed/25287761 - carb restriction as a
diabetes managment approach.
https://www.ncbi.nlm.nih.gov/pubmed/20071648/ - No assosiation between SFA and CVD

Cardiovascular health:
https://www.ncbi.nlm.nih.gov/pubmed/22905670 - LC improved CVD markers
https://www.ncbi.nlm.nih.gov/pubmed/29199027 - long term keto diet shows no
problems in CVH
http://bjsm.bmj.com/content/51/24/1743 - Total Fat and SatFat intake has no
significant effect
http://care.diabetesjournals.org/content/early/2014/07/29/dc14-0845 - LC on
GC and CD risk factors. More effective than HC.
https://www.ncbi.nlm.nih.gov/pubmed/20679559 - favourable results after 2
years on LC
https://www.ncbi.nlm.nih.gov/pubmed/2643423 - Mennesota Coronary Survey, no
effect on heart disease from fat
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475232/ - No increase in stroke
from eating high sat fat.
https://academic.oup.com/ajcn/article/87/3/567/4633410 - high sat fat diet
beneficial effect on risk factors
http://bjsm.bmj.com/content/51/24/1743 - Harcombe, no sig dif in CVD from
fat and sat fat intake. Guidelines are nonsense.
https://academic.oup.com/ajcn/article/106/1/35/4569819 - increase in CVD
from low-fat (WHI, 48k people)
https://www.sciencedirect.com/science/article/pii/0091743579900331?via%3Dihub
- 2-3 times higher rate of stroke in Japanese with low cholesterol
https://www.sciencedirect.com/science/article/pii/S0140673657906141 - Yudkin
CVD and fat not linked
http://www.bmj.com/content/346/bmj.e8539 - increased egg consumption not
linked to CVD

Lipoprotein Breakdown:
http://onlinelibrary.wiley.com/doi/10.1002/jss.400130107/epdf
http://atvb.ahajournals.org/content/atvbaha/21/3/386.full.pdf

Calories:
http://care.diabetesjournals.org/content/16/1/21 - weight gain despite
lower calories
https://academic.oup.com/ajcn/article/104/2/324/4564649 - energy expenditure
slightly higher on a LC diet, despite equal calories.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058172 - LF
diet inhibits energy expenditure.
https://jamanetwork.com/journals/jama/fullarticle/1199154 - highest resting
metabolism on LC
https://www.researchgate.net/publication/6506483_A_high-
fat_ketogenic_diet_induces_a_unique_metabolic_state_in_mice- in mice, LC diet
on same calories out performs as high sucrose and control

Cholesterol:
https://academic.oup.com/ajcn/article/102/3/573/4564305 - higher HDL on cheese
and meat diets, over low fat. Also more fat in poop!
https://www.ncbi.nlm.nih.gov/pubmed/10704609 - Chondroitin sulfate helps bind
oxidised LDL
https://www.sciencedirect.com/science/article/pii/S0026049513002230 -
improvements in blood lipids and inflamation on LCHF.
https://www.sciencedirect.com/science/article/pii/S0140673601055532#fig1 -
Honolulu Heart Program. Low cholesterol people died more
https://academic.oup.com/jn/article/135/6/1339/4663837 - improvements of
lipoprotein profile, independent of weight
https://www.cabdirect.org/cabdirect/abstract/19361403668 - No relation
between blood cholesterol and atherosclerosis
https://www.researchgate.net/publication/15427298_Lack_of_Association_Between_Chole
sterol_and_Coronary_Heart_Disease_Mortality_and_Morbidity_and_All-
Cause_Mortality_in_Persons_Older_Than_70_Years - high cholesterol in old
people is not associated with all cause mortality
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809530/ - inverse association
between cholesterol and infections
https://academic.oup.com/jn/article/138/2/272/4664988 - HDL cholesterol
increases when eating eggs on low-carb diet
https://www.ncbi.nlm.nih.gov/pubmed/3773199 - MRFIT, chart data.
http://circ.ahajournals.org/content/96/8/2520 - fasting triglycerides good
indicator of atherosclerosis risk
https://www.ncbi.nlm.nih.gov/pubmed/4596028 - Maasai, low cholesterol high
dairy and meat
https://academic.oup.com/jn/article-abstract/59/1/39/4722525 - No link between
dietary cholesterol and blood serum cholesterol (Keys paper)
https://www.ncbi.nlm.nih.gov/pubmed/27292972 - LDL is associated with equal
or greater longevity.

Neurological problems:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816269/ - Keto diet helps fight
Chronic Cluster Headache
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649682/ - ketone bodies have neuro-
protective properties as well as anti-cancer.
https://www.ncbi.nlm.nih.gov/pubmed/14769487 - brain produces it's own
ketones
https://www.ncbi.nlm.nih.gov/pubmed/25832906 - Ketones help in Alzheimers.
https://www.ncbi.nlm.nih.gov/pubmed/18625458 - Ketone bodies as a treatment
for Alzheimers.
https://www.sciencedirect.com/science/article/pii/S0197458003000873 - higher
ketones show higher cognitive performance with alzheimers patients.
http://www.pnas.org/content/97/10/5440 - ketone bodies protect
neurons.
http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2008.01852.x/full -
neurotrauma and ketones
http://www.pnas.org/content/101/1/284.long - Alzhimers, show low rates of
cerebral glucose uptake
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/ - Alzhiemers is Type 3
diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC292907/ - ketones replace glucose
as primary fuel source when glucose not available
http://coconutketones.com/wp-
content/uploads/2016/10/KashiyawaVeechBOHBprotectsneurons2000.pdf -
ketones protect neurons in alzhimers and parkinsons patients
https://www.researchgate.net/publication/264977274_Lower_brain_18F-
Fluorodeoxyglucose_uptake_but_normal_11C-Acetoacetate_metabolism_in_mild_Alzheimer
%27s_Disease_dementia - glucose uptake in alzhimers lower than normal,
ketones not
https://www.researchgate.net/publication/290442938_Can_ketones_compensate_for_deter
iorating_brain_glucose_uptake_during_aging_Implications_for_the_risk_and_treatment_
of_Alzheimer%27s_disease - MCT 8-10 at 20-70g a day induces nutritional
ketosis for the brain
https://www.researchgate.net/publication/258254952_Retrospective_cohort_study_of_th
e_efficacy_of_caprylic_triglyceride_in_patients_with_mild-to-
moderate_Alzheimer's_disease - improvements in alzheimers on KB (cohort)
https://www.researchgate.net/publication/264389684_Effects_of_Caprylic_Triglyceride
_on_Cognitive_Performance_and_Cerebral_Glucose_Metabolism_in_Mild_Alzheimer
%27s_Disease_A_Single-Case_Observation - improvements in mild alzheimers on
KB
https://www.sciencedirect.com/science/article/pii/S2214647415000021 - MCT
supplements improved memory in those with cognitive disorders
https://www.jstage.jst.go.jp/article/jos/65/8/65_ess16069/_article - MCT
(lauric acid) appears to directly increase ketone bodie concentration in the brain,
ketones produced in the brain
https://www.sciencedirect.com/science/article/pii/S0197458012006112 -
improvements in mice taking ketone ester
https://www.sciencedirect.com/science/article/pii/S0197458015005916 -
reduced amyloid burden, and reduced oxidative stress. greatly improved
learning and memory ability
http://www.tahomaclinic.com/Private/Articles4/Depression/Hasselbalch%201996%20-
%20cerebral%20blood%20flow%20and%20carbohydrate%20metabolism%20during%20acute
%20hyperketonemia.pdf - high ketone bodies in the brain cause uptake of them
and decrease in glucose even if glucose is present. Increased cerebral blood flow
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181302/ - Dr. Whals "cures" her MS
through dietary means and electo therapy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074854/ - autism
https://www.sciencedirect.com/science/article/pii/S0304394011009013 -
adenosine, diet and autism

Anti-biotics:
https://www.researchgate.net/publication/319663867_Microbes_and_Alzheimer's_disease
- microbes may effect alzheimers
https://www.ncbi.nlm.nih.gov/pubmed/4670656 - C12 and C18:1 exhibit
antimicrobial effects
https://www.ncbi.nlm.nih.gov/pubmed/3032090 - Medium chain fatty acids and
long chain unsaturated are highyl active against enveloped viruses
https://link.springer.com/article/10.1007/s11746-014-2562-7- lauric acid makes up
45-54% of coconut oil. Has anti-biotic properties (soap!)
https://www.ncbi.nlm.nih.gov/pubmed/227969 - various viruses decrease by lipid
anti-viral activity

Laziness, exercise and weight gain:

https://link.springer.com/article/10.1007/s40279-017-0828-6- no link between
sedentary behaviour and any measure of obesity
http://bjsm.bmj.com/content/early/2015/05/07/bjsports-2015-094911 -
Exercise does not promote weight loss. Can't outrun a bad diet
https://www.researchgate.net/publication/15484992_Time_course_for_exercise-
induced_alterations_in_insulin_action_and_glucose_tolerance_in_middle-aged_people
- increased insulin sensitivity after exercise

Inflammation/oxidative stress:
https://www.researchgate.net/publication/261996571_Advice_to_follow_a_low-
carbohydrate_diet_has_a_favourable_impact_on_low-
grade_inflammation_in_type_2_diabetes_compared_with_advice_to_follow_a_low-fat_diet
- lower on LC than LF
https://www.sciencedirect.com/science/article/pii/S1098882311000748 - omega-
3 reduces inflammation and cancer
https://www.researchgate.net/publication/285754494_Ketogenic_diet_decreases_oxidati
ve_stress_and_improves_mitochondrial_respiratory_complex_activity -
ketones decrease oxidative stress
https://www.ncbi.nlm.nih.gov/pubmed/25686106 - ketos lower inflammation

Gut:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402009/ - LCD improves
gastrointestinal microbiota.
http://www.mdpi.com/2072-6643/7/3/1565/htm - Gliaden/gluten increases gut
permeability in everyone
https://genie.weizmann.ac.il/pubs/2014_nature.pdf - Artificial sweetners
alter gut micro
http://jcs.biologists.org/content/joces/113/24/4435.full.pdf - zonulin
https://www.nejm.org/doi/pdf/10.1056/NEJMoa1400697 - gluten and celiacs
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033387 -
microbiome and gluten

Vitamins and Minerals:

https://www.ncbi.nlm.nih.gov/pubmed/2538051 - high phytate intake linked to
much lower iron absorbtion
https://www.nature.com/articles/531S12a?WT.ec_id=NATURE-
20160303&spMailingID=50825784&spUserID=MTgxNDAzNTIyOTgwS0&spJobID=880255771&spRepor
tId=ODgwMjU1NzcxS0 - why we eat meat
https://www.tandfonline.com/doi/abs/10.1080/09637480701553741?journalCode=iijf20
- nutrient levels in seafood
https://academic.oup.com/jn/article/134/11/3100/4688389 - Vitamin K (in meat
and dairy) intake associated with reduced risk of CHD
https://www.cabdirect.org/cabdirect/abstract/19591401253 - Carotene uptake
much higher when fat is added
https://academic.oup.com/ajcn/article/80/2/396/4690323 - carotenoid
bioavailibility much lower without fat. Almost 0 uptake without fat
http://www.direct-ms.org/pdf/EvolutionPaleolithic/Eaton%20Paleo%20Nutri%20Review
%20EJCN.pdf - paleo man consumed much more vitamins than the modern diet.
http://jandonline.org/article/S2212-2672(14)01468-3/abstract?rss=yes -
dietary fat increases Vitamin D uptake.
Clever Eating - low iron levels despite taking supplements.
http://www.nature.com/articles/pr2015248 - lack of pre-natal iron causes
decreased synapse formation.
http://www.bourre.fr/pdf/publications_scientifiques/259.pdf- pt1.
micronutrients and their uses.
http://www.bourre.fr/pdf/publications_scientifiques/260.pdf- pt2. omega acids

Information supression:
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003460 -
sugar industry show sugar damages gut flora and can lead to heart problems.

Statins:
http://psychology.usf.edu/News/ExpertRevClinPharmacol2015StatisticalDeceptionInStat
inResearch.pdf - statistical deception showing statins are safe
https://www.researchgate.net/publication/14394659_Men_treated_with_hyoplidemic_drug
s_complain_more_frequently_of_erectile_dysfunction - increases frequency of
erectile dysfunction
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1691918 -
muscle pain in statin users
https://www.sciencedirect.com/science/article/pii/S0002914915023152 -
increased risk of kidney disease
http://www.eje-online.org/content/173/2/155.full - significantly lower
testosterone in statin users
http://care.diabetesjournals.org/content/32/10/1924 - possible increase in
rates of diabetes on statins
http://www.bmj.com/content/340/bmj.c2197 - increased risk of liver dyfunction,
renal failiure myopathy and cataracts.
http://www.onlinejacc.org/content/50/5/409 - risk of cancer associated
with low LDL-C
https://www.ncbi.nlm.nih.gov/pubmed/25754552/ - decrease in insulin
sensitivity and increased diabetes
http://courses.ahc.umn.edu/pharmacy/5822/Ray_Statins%20and%20all-cause%20mortality
%20in%20high-risk%20primary%20prevention_Arch%20Int%20Med%202010.pdf - all cause
mortality not improved on statins
https://link.springer.com/article/10.2165/00003495-200464002-00005 -
lipitor 36% stat

Kidneys:
http://cjasn.asnjournals.org/content/7/7/1103.long - Low carb, high protein, no
negative effects compared to low-fat
http://www.kidney-international.org/article/S0085-2538(15)30174-5/fulltext -
insulin prevents salt leaving the kidneys

Insulin:
http://care.diabetesjournals.org/content/16/1/21 - patients gain weight
taking insulin for Diabetes.
https://www.ncbi.nlm.nih.gov/pubmed/9742976 - greater weight gain due to
insulin than anything else.
https://www.ncbi.nlm.nih.gov/pubmed/24172304 - insulin resistance is the
best indicator of weight re-gain
http://joe.endocrinology-journals.org/content/early/2017/01/04/JOE-16-0449.full.pdf
 - insulin resistance causes obesity.
https://jci.org/articles/view/96139 - insulin resistance leads to imflammation
http://atvb.ahajournals.org/content/32/8/1754 - Insulin resistance leads to
CVD
https://www.ncbi.nlm.nih.gov/pubmed/27391319/ - long term use of insulin as a
treatment for TIIDM low efficacy. Leads to weight gain and hypoglycaemia
http://www.biochemj.org/content/475/3/561 - Insulin lowers mitochondrial energy
use in brown fat tissue.

Leptin:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281561/ - Leptin resistance, obese
people have higher circulating levels
https://academic.oup.com/ajcn/article/89/3/991S/4596849 - what is leptin?

PCOS:
https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-35
- reduction in symptoms of polysystic ovary syndrome. 2 previously
infertile women became pregnant

Metabolic Syndrome:
https://static1.squarespace.com/static/59ae01e849fc2b19c93fbb46/t/5a1ce89ae2c483f5a
d47b724/1511844041802/Induced+and+Controlled+Dietary+Ketosis - improved markers
for SynX on LC
https://www.nhlbi.nih.gov/health-topics/metabolic-syndrome - What is it?
https://link.springer.com/article/10.1007%2Fs11745-008-3274-2 - more
favourable impact on MetSyn than LF
https://link.springer.com/article/10.1007/s11745-001-0784-7- increase CLA
improves markers as well as promote muscle
https://www.sciencedirect.com/science/article/pii/S0163782708000167 - Keto
diet improves all markers for Metabolic Syndrome
https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-31
- metabolic syndrome is a collection of markers and carb restriction
helps them all.
http://annals.org/aim/article-abstract/718265/effect-low-carbohydrate-diet-
appetite-blood-glucose-levels-insulin-resistance - improvements on subjects
doing low carb, also weight loss
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2530901 -
eating more subsidised foods (corn, soybean, wheat, rice, sorghum) associated
with poor health

Saturated Fat:
https://academic.oup.com/ajcn/article/34/8/1552/4812510 - Tokelau, high
satfat and low CVD
https://www.ncbi.nlm.nih.gov/pubmed/8450295 - Kitava, high fat diet, low
cvd
https://pdfs.semanticscholar.org/66dc/d7aca8e88b2f53aae9db2d7800edaf3df779.pdf
- Litava low CVD, no grains, oils or sugar.
https://jamanetwork.com/journals/jama/article-abstract/1721083?redirect=true -
italian population, high st fat intake low cvd
https://academic.oup.com/ajcn/article-abstract/20/5/462/4787773?cited-
by=yes&legid=ajcn;20/5/462&related-urls=yes&legid=ajcn;20/5/462 - Indians, 10
times higher fat intake, 15 times less heart disease
https://www.ncbi.nlm.nih.gov/pubmed/20071648/ - meta-analysis, no increase in
CVD from saturated fat
http://www.bmj.com/content/351/bmj.h3978/ - not associated with all cause
mortality. Trans fats are.
http://www.bmj.com/content/353/bmj.i1246 - replacing SFA with PUFA does not
increase mortality
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113605 -
 saturated fat does not cause metSyn, increasing carbs does though
http://diabetes.diabetesjournals.org/content/15/10/723.long- rise in ketones
after concuming MCT but not corn oil.
Breast Milk is 10-17% MCT - Mary Newport MD, Medium Chain Triglycerides and
Ketones for Alzheimers and Other Disorders
https://academic.oup.com/jn/article/132/3/329/4687297 - MCT might be more
satiating than LCT
https://nutritionj.biomedcentral.com/articles/10.1186/s12937-017-0254-5 -
META ANALYSIS, replacing SFA with PUFA does NOT increase mortality
https://www.bmj.com/content/353/bmj.i1246 - META ANALYSIS, Minesota Coronary
reanalysis, no benefit from replacing SFA with PUFA, increased mortality
https://openheart.bmj.com/content/2/1/e000196?sid=7f05f28c-917b-462e-ab41-
c1741ddb099c - META ANALYSIS, Harcombe, no improvements with SFA
reduction.

Fat:
https://www.ncbi.nlm.nih.gov/pubmed/21814506 - Fat can convert into sugar,
not just glycerol. Not energy efficient, helps explain increasd weight loss on low-
carb.
http://cristivlad.com/energy-levels-under-ketosis-fats-carbs-and-atp/ -
Calculations behind fat and glucose
https://drive.google.com/file/d/1iezP2O19IlXhK_bI_WIo9DvZxYMBCejF/view -
LC diet appears to mobolise certain fat stores other diets may not.
https://www.researchgate.net/publication/13087386_Lipoprotein_lipase_and_the_dispos
ition_of_dietary_fatty_acids - LPL regulates fat uptake in adipose, appears to
be regulated by things such as insulin and maybe leptin.
https://academic.oup.com/ajcn/article/86/2/276/4633078 - when eating low
carb cause the body to shift to burning fatty acids
https://www.sciencedirect.com/science/article/pii/088915759290037K - CLA
found in ruminant meat and products
https://www.ncbi.nlm.nih.gov/pubmed/10531600 - CLA content of milk from cows
on different diets
http://www.bourre.fr/pdf/publications_scientifiques/254.pdf- adding omega-3 to
animals diets increases levels in their meat
https://www.researchgate.net/publication/230187178_N-
3_fatty_acids_and_conjugated_linoleic_acids_of_longissimus_muscle_in_beef_cattle
- grass fed cattle have more n-3
https://jamanetwork.com/journals/jama/article-abstract/418882?redirect=true -
triglycerides increased on low fat diet.
https://www.ncbi.nlm.nih.gov/pubmed/24723079 - current evidence does not support
hypothesis that PUFA increased, and decreased SatFat is good for CVH
http://circ.ahajournals.org/content/40/1S2/II-1 - Dayton, increase veg oil.
Lower atherosclerosis, higher overall mortality.
https://www.karger.com/Article/Pdf/229002 - total fat not associated with CVD
https://www.researchgate.net/publication/266571664_Rethinking_fat_as_a_fuel_for_end
urance_exercise - ketones as a fuel source for exercise and mental
performance
https://www.researchgate.net/publication/9706857_Carbohydrate-induced_and_fat-
induced_lipemia - blood triglycerides highest on high-carb diet.
https://link.springer.com/article/10.1007/s11010-005-9001-x- ketogenic diet
safe to use long term
http://www.nejm.org/doi/full/10.1056/NEJM199301283280404 - insulin
sensitivity tied to PUFA make up of the cells.
https://jamanetwork.com/journals/jama/article-abstract/321847?redirect=true -
low-cal, low-fat diet usually unsuccessful due to ease carbs are converted
into fat
http://www.dhaomega3.org/Overview/Conversion-Efficiency-of-ALA-to-DHA-in-Humans
- ALA conversion to DHA is poor
http://diabetes.diabetesjournals.org/content/60/1/88 - VLDL secretion increased
in diabetics
https://www.ncbi.nlm.nih.gov/pubmed/24666665 - META ANALYSIS, high fat
lowers TGC, increase HDL, reduce BP
https://www.scribd.com/document/321042656/fat-in-the-diet-and-mortality-from-heart-
disease-yerushalmy-hilleboe - Rebuttle to Keys, 22 countries fat does not
correlate with CVD

Liver:
https://academic.oup.com/jcem/article/101/2/644/2811018 - NAFLD
causative effect on CVD.
https://www.cabdirect.org/cabdirect/abstract/19671404711 - cirrhosis of the liver
possibly due to corn oil

Cancer:
http://www.bmj.com/content/1/3261/1116.2 - No cases of cancer in South
African, Himalayan or South American rural populations
https://archive.org/stream/naturalhistoryof00williala#page/14/mode/2up -
Almost no cases of cancer in rural africa
https://link.springer.com/article/10.1007/s10555-014-9495-3- LC diet synergises
with radiation therapy
https://www.annualreviews.org/doi/pdf/10.1146/annurev.nu.12.070192.002135 -
Low cholesterol correlates with increases in some types of cancer
http://cancerres.aacrjournals.org/content/51/22/6118 - greatly reduced rates of
Breast cancer in rats fed CLA
https://www.researchgate.net/publication/13612377_Opposite_effects_of_linoleic_acid
_and_conjugated_linoleic_acid_on_human_prostatic_cancer_in_SCID_mice - drastic
reduction in metasteses on CLA in mice
https://www.tandfonline.com/doi/abs/10.1207/S15327914NC382_2 - inverse
asociation between CLA and breast cancer in Finish women
http://cancerres.aacrjournals.org/content/canres/52/7_Supplement/2040s.full.pdf
- increases in linoleic acid increased rates of cancer in rats
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994795/ - inflammation and cancer
https://academic.oup.com/ajcn/article/87/5/1405/4650653 - increase in
dairy, showed reduction in prostate cancer (Table 5)
https://www.ncbi.nlm.nih.gov/pubmed/11403817 - eating fatty fish lowers
rates of prostate cancer
http://europepmc.org/articles/PMC2374335 - Omega-3 lowers rates of prostate
cancer
https://www.sciencedirect.com/science/article/pii/S0271531711000030 - high
ratio of n-6 to n-3 leads to prostate cancer
http://gut.bmj.com/content/61/1/135 - n-3 can be used to synergise as a cure
for cancers. - colorectal
https://www.researchgate.net/publication/51504626_Omega-
3_fatty_acids_induce_apoptosis_in_human_breast_cancer_cells_and_mouse_mammary_tissu
e_through_syndecan-1_inhibition_of_the_MEK-Erk_pathway - lower rates of
brast cancer with omega-3
https://uthscsa.influuent.utsystem.edu/en/publications/omega-3-fatty-acid-
inhibition-of-prostate-cancer-progression-to-h - omega-3 helps with prostate
cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941741/ - A lot of cancer is to do
with tumour cell mitochondriaal energy metabolism
https://www.ncbi.nlm.nih.gov/pubmed/22563484/ - Keto diet significantly
increases the effect of radiation
http://pubs.sciepub.com/AJMCR/4/8/8/index.html - treatment for solf palate
cancer, nothing but keto. halted progression, no symptoms no side ffcts.
https://academic.oup.com/jnci/article/101/18/1272/2515675 - increased insulin
levels, significaly linked to prostate cancer
https://www.researchgate.net/publication/302591789_Anti-
Tumor_Effects_of_Ketogenic_Diets_in_Mice_A_Meta-Analysis - reduced tumor
growth in mice on KD
https://www.researchgate.net/publication/269717016_Roles_of_Caloric_Restriction_Ket
ogenic_Diet_and_Intermittent_Fasting_during_Initiation_Progression_and_Metastasis_o
f_Cancer_in_Animal_Models_A_Systematic_Review_and_Meta-Analysis - KD and
caloric restriction effective against cancers in animal studies
http://www.jlr.org/content/early/2014/02/06/jlr.R046797.full.pdf - cancer
tumors have increased reliance on glucose and restriction of carbs helps in animal
models
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-8-122 - gastic
cancer cells grow slower on KD diet supplemented with Ohm3 and MCT
https://www.researchgate.net/publication/273638512_Growth_of_Human_Colon_Cancer_Cel
ls_in_Nude_Mice_is_Delayed_by_Ketogenic_Diet_With_or_Without_Omega-
3_Fatty_Acids_and_Medium-chain_Triglycerides - unrestricted KD works
https://www.researchgate.net/publication/19937567_A_comparison_of_long-
chain_triglycerides_and_medium-
chain_triglycerides_on_weight_loss_and_tumour_size_in_a_cachexia_model - doesn't
work with long chain triglycerides
https://www.researchgate.net/publication/295241299_Long-
term_High_Fat_Ketogenic_Diet_Promotes_Renal_Tumor_Growth_in_a_Rat_Model_of_Tuberous
_Sclerosis - KD makes renal tumor in rats WORSE
http://clincancerres.aacrjournals.org/content/clincanres/19/14/3905.full.pdf -
KD enhances response to chemo in lung cancer
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065522 -
KD enhances response to hyperbaric oxygen therapy
https://bpccancerprotocol.wordpress.com/2013/07/08/effects-of-a-ketogenic-diet-on-
tumor-metabolism-and-nutritional-status-in-pediatric-oncology-patients-two-case-
reports/ - decreased glucose uptake of tumour in brain cancer
https://www.ncbi.nlm.nih.gov/pubmed/18541570 - higher GI diets have
increased risk of colorectal and endometrial cancer
https://www.ncbi.nlm.nih.gov/pubmed/3788845 - lisions in rats on glucose
and ketone bodies

Diseases of Civilisation:
https://archive.org/stream/physiologicalmed00hrdl#page/188/mode/2up - Severe
lack of diseases of civilisation in rural populations
https://www.sciencedaily.com/releases/2001/05/010529071125.htm - Tall
Native Americans
http://www.nytimes.com/2007/06/27/world/middleeast/27mummy.html -
Egyptian mummy, diabetes and obesity
https://en.wikipedia.org/wiki/Hemiunu - Fat Egyptian statue
https://upload.wikimedia.org/wikipedia/commons/a/a3/Limestone_statuette_of_Akhenate
n%2C_Nefertiti%2C_and_a_princess._Reign_of_Akhenaten._From_Amarna
%2C_Egypt._The_Petrie_Museum_of_Egyptian_Archaeology%2C_London.jpg - Fat
Akhenaten
https://www.studyblue.com/notes/note/n/exam-2/deck/1264908 - Full Body Akhenaten
https://upload.wikimedia.org/wikipedia/commons/7/7b/Inside_the_British_Museum
%2C_London_-_DSC04210.JPG - Fat Pharaoh
http://www.worldcat.org/title/migration-and-health-in-a-small-society-the-case-of-
tokelau/oclc/24544582 - Tokelau, poor health after migrating
https://rosemarycottageclinic.files.wordpress.com/2013/02/cereal-
free_diet_and_dental_caries.pdf - Poor tooth health on cereals
https://jamanetwork.com/journals/jama/article-abstract/267994?redirect=true -
Steffansson paper.

Food History:
http://nephicode.blogspot.co.uk/2017/07/does-corn-prove-others-were-in-land-
of_13.html - Teosinte
https://academic.oup.com/jhmas/article/63/2/139/772615 - How Low Fat became a
thing
http://sugarscience.ucsf.edu/hidden-in-plain-sight/#.WqpYiE27Lop - added sugar
http://apps.who.int/iris/bitstream/10665/43281/1/9241593431.pdf?ua=1&ua=1 -
WHO food guidelines (p12)
https://pastebin.com/vRApKZYZ - history of fruit references
https://health.gov/dietaryguidelines/2015-scientific-report/PDFs/11-Part-D-Chapter-
6.pdf 2015 Us dietry guidelines
https://shootingthemessenger.blog/tag/claire-julsing-strydom/ - prosecution
of Tim Noakes
https://nutritionconfidence.wordpress.com/2015/02/19/a-word-from-claire-julsing-
strydom-adsas-president-on-sponsorships/ - Sponsors of the prosecution for
Noakes
https://academic.oup.com/jn/article/133/11/3886S/4818038 - humans evolved to
eat animal products
http://www.pnas.org/content/107/22/10002.full - Hominins eating all sorts of
animals for millions of years.
https://academic.oup.com/ajcn/article/71/3/682/4729121 - hunter-
gatherer analysis. 55-65% of diet is animal based.
https://academic.oup.com/ajcn/article/70/3/560s/4715011 - current diet
has 30:1 ratio Ohm 6 - Ohm 3
https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-
society/article/the-ancestral-human-diet-what-was-it-and-should-it-be-a-paradigm-
for-contemporary-nutrition/36E3866D0207692F8CA1CCA3BD947055- the ancestral diet,
percentages of fats, etc.
https://www.sciencedirect.com/science/article/pii/S0047248404001605 -
evolution of eating meat, explains why we wean early
Your Heart Has Nine Lives: Nine Steps to Heart Health - book issues to doctors,
thanks Wesson Oil
https://www.ncbi.nlm.nih.gov/pubmed/13441073 - rebuttle to Keys, all the
data points, showing no connection (https://www.scribd.com/document/321042656/fat-
in-the-diet-and-mortality-from-heart-disease-yerushalmy-hilleboe)
https://www.sciencedirect.com/science/article/pii/S002561961163262X -
humans used to eat only natural foods, and were healthy

Atherosclerosis:
https://atherosclerosisremedy.wordpress.com/category/atherosclerosis-in-the-united-
states/ - Levels in US
https://thescienceofnutrition.files.wordpress.com/2014/03/a-controlled-clinical-
trial-of-a-diet-high-in-unsaturated-fat-in-preventing-complications-of-
atherosclerosis.pdf - LA, Veterans. Dayton, reduction in atherosclerosis, no
reduction in mortality, increase in cancer.
https://www.slideshare.net/Zahccc/the-los-angeles-veterans-trial-a-negative-
dietary-trial - LA veterns critique
https://thescienceofnutrition.files.wordpress.com/2014/03/atherosclerosis-in-the-
masai.pdf - G.Mann, lack of atherosclerosis deaths in the Massai
https://www.ncbi.nlm.nih.gov/pubmed/26672634/ - NAFLD associated with worse
CVD regarldless of other things
https://academic.oup.com/ajcn/article-abstract/25/8/737/4733245 - Eskimo, low
rates of atherosclerosis

Lecutures/references:
https://oldwayspt.org/programs/oldways-common-ground/finding-common-ground-program-
and-presentations - various on diet
https://www.youtube.com/watch?v=O8TqRyxawkE - Alessio Fasano, How nutrition
can shape got microbiota
https://www.youtube.com/watch?v=Q2UnOryQiIY - Nina Teicholz, Vegetable oil
the unknown story
https://www.youtube.com/watch?v=uJ0WJOQzrgg - Sally Fallon, Mary Enig,
Oiling of America
https://a1b29423df1c76886901-
30f50311cbe25c4d753e0084f1029763.ssl.cf4.rackcdn.com/BigFatSurprise_Notes-
Biblio.pdf - Big Fat Surprise reference list

Resistant Starch:
https://www.hsph.harvard.edu/nutritionsource/2015/11/16/ask-the-expert-legumes-and-
resistant-starch/ - What is resistant starch
https://www.sciencedirect.com/science/article/pii/S0144861703001929 - what it does

Salt:
http://heartfailure.onlinejacc.org/content/4/1/36 - salt may not be a
problem at all
http://europepmc.org/articles/PMC4785822 - sodium not associated with 10-year
mortality. Trends toward at very high rates.
http://www.bmj.com/content/325/7365/628.1 - unclear of any relation, between salt
intake and CVD.
http://care.diabetesjournals.org/content/34/3/703 - salt linked to reduced
insulin sensitivity
http://heartfailure.onlinejacc.org/content/4/1/24 - sodium restriction may
be a negative thing on people with heart failure

Sweeteners:
http://www.nature.com/articles/nature13793 - artificial sweeteners linked
to glucose intolerance in mice

Statins:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890684/ - statin use in the UK
http://www.bmj.com/content/347/bmj.f6123 - statin use in people of low risk is
not helpful
https://www.ncbi.nlm.nih.gov/pubmed/6361299 - cholesterol lowering drug,
did not reduce total death, but did reduce CHD

Other:
https://www.nytimes.com/2014/09/02/health/low-carb-vs-low-fat-diet.html -
low carb vs low fat diet
https://ancestral-nutrition.com/the-plant-based-culture-myth-and-work-of-weston-a-
price/ - Weston Price food and dentistry + meat makes you more dominant
https://www.nytimes.com/2013/02/24/magazine/the-extraordinary-science-of-junk-
food.html?pagewanted=all - bliss point of food
https://www.ncbi.nlm.nih.gov/pubmed/20329590 - the brain is 60% fat and needs
fat to grow
https://idmprogram.com/insulin-causes-weight-gain-hormonal-obesity-iv/ - insulin
obesity, etc.
http://www.dayvillesupply.com/hay-and-horse-feed/calorie-needs.html -
calories in grass
http://www.nejm.org/doi/full/10.1056/NEJMsr043743 - life expectancy no-
longer increasing
https://www.nytimes.com/2016/09/13/well/eat/how-the-sugar-industry-shifted-blame-
to-fat.html - How the sugar industry shifted the blame to fat
https://www.cdc.gov/nchs/healthy_people/hp2000.htm - increase sales of
processed food
https://www.ncbi.nlm.nih.gov/pubmed/14527626 - Fat babies evolved for a
reason
https://www.ncbi.nlm.nih.gov/pubmed/20086073 - All about Fructose
https://www.ncbi.nlm.nih.gov/pubmed?term=A+decade+of+reversal
%3A+an+analysis+of+146+contradicted+medical+practices&TransSchema=title&cmd=details
search - Up to 50% of medical research is wrong.
https://jamanetwork.com/journals/jama/fullarticle/1104821 - Medical research is
often wrong
https://www.virtahealth.com/ - diabetes reversal clinic
TO READ THROUGH

http://www.direct-ms.org/pdf/EvolutionPaleolithic/Eaton%20Paleo%20Nutri%20Review
%20EJCN.pdf - not great

https://www.ncbi.nlm.nih.gov/pubmed/16053240
https://www.tandfonline.com/doi/abs/10.1080/10284150500047161

http://diabetes.diabetesjournals.org/content/60/1/88

https://onlinelibrary.wiley.com/doi/abs/10.1002/oby.21108

The Cholesterol and calorie hypothesis are both dead - it is time to focus on the
real culprit: insulin resistance. pharm-jour

Dietary guidelines and health - is nutrition science up to the task - bmj

(response)

The plant based culture myth and the work of weston A price - ancestral nutrition

A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell
signalling throughout evolution

long chain n-3 polyunsaturated fatty acids in plasma in British mea-eating,

vegetarian, and vegan men

Iron, magensium, vitamind d and zinc deficiences in children presenting with

symptoms of Attention-Deficit/Hyperactivity Disorder

Is it true that lack of iodine really causes brain damage? WHO 2013

Studies on the bioavailability of zinc in man II absorption of zinc from organic

and inorganic sources

Micronutrient status and intake in omnivores, vegetarians and vegans in Switzerland

USDA Agriculture research service national nutrient database for standard

reference. release 28. May 2016

Relationship between Long-chain n-3 polyunsaturated fatty acids and Autism Specturm
Disorder: systematic review and meta-analysis of case-control and randomised
controlled trials.

Nutritional and dietary interventions for autism and spectrum disorder: a

systematic review

Examining the relationship between ADHD and overweight in children and adolescents

The role of nutritional supplements in the treatment of AHDH: what the evidence
says

Diet and ADHD; reviewig the evidence: a systematic review

http://apjcn.nhri.org.tw/server/apjcn/ProcNutSoc/1990-1999/1995/1995%20p1-10.pdf -
no reivew of dietary guidelines Australia

Reduced or modifier dietary far for preventing cardiovascular disease 2011

Meta-analysis of prospective cohort studies evaluating the association of saturated
fat with cardiovascular disease 2010

A systematic review of the evidence supporting a causal link between dietary

factors and coronary heart disease 2009

Intake of saturated and trans unsaturated fatty acids and risk of all cause
mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-
analysis of observational studies 2015

Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data

from Minnesota Coronary Experiment 2016

The effect of replacing saturated fat with mostly n-6 polyunsaturated fat on
coronary heart disease: a meta-analysis of randomised controlled trials. 2017

Low Fat Dietary Pattern and Risk of Cardiovascular Disease: The Women's Health
Initiative Randomized Controlled Dietary Modification Trial (700m$, most expensive
trial ever)

http://bjcardio.co.uk/2015/07/lipids-module-1-lipid-metabolism-and-its-role-in-
atherosclerosis-3/

Pathophysiology of Lipoprotein Oxidation, Lipoproteins - Role in Health and

Disease, Prof. Gerhard Kostner 2012

Association of low-density lipoprotein pattern with mortality after myocardial

infarction: insights from the TRIUMPH study

Dr. Paul Mason - 'Saturated fat is not dangerous' - cholesterol stuff

http://www.dhaomega3.org/Overview/Conversion-Efficiency-of-ALA-to-DHA-in-Humans
- ALA supplementand flax seed oil do NOT raise DHA

Small dense LDL is more susceptible to glycation than more bouyant LDL in Type 2
diabetes - 2013

Lipid advanced glycosylation: pathway for lipid oxidation in vivo

Low-density lipoprotein particles size as an independent predictor of glycated low-

density lipoprotein level - 1999

LDL biochemical modifications: a link between atherosclerosis and aging. - 2015

Inflammatory markers, lipoprotein components and risk of major cardiovasuluar

events in 65,005 men and women in the Apolipoprotein MOrtality RISk study -
increase serum glucose increases risk of infarction when LDL is the same.

Hyperinsulinemia as an independant Risk Factor for Ischemic Heart Disease - 1996 -

increased insulin with high Apop B shows great increase in heart disease

The effect of statins on average survival in randomised trials, an analysis of end

point postponement 2015 - 5.2 days increased life in people with previous heart
disease

Balancing proportions of competing omega-3 and omega-6 highly unsaturated fatty

acids (HUFA) in tissue lipids 2015 - increasing levels of one decreases levels of
the other

Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty
acids and the risk of primary cardiac arrest

Blood levels of long-chain n-3 fatty acids and the risk of sudden death

Omega-3 fatty acid blood levels clinical significance update -- levels of EPA+DHA
in the population

Effects of time on feed on beef nutrient composition - after 196 days eating grain
percent of omega-3 of total fat drops from 3% to 0%